Clinical Trials Sponsored by The Children's Trust, United Kingdom

Total 504 results

Northumbria Healthcare NHS Foundation Trust
Newcastle-upon-Tyne Hospitals NHS Trust; National Institute for Health Research... and other collaborators

Completed

Mortality and Symptom Burden Post Hospitalisation With COPD (MoSHCOPD)

Pulmonary Disease, Chronic Obstructive | Emphysema | Chronic Bronchitis | Pulmonary Disease, Obstructive | Chronic Bronchitis With Airways Obstruction | Chronic Bronchitis With Acute Exacerbation

United Kingdom
University of Miami
ConnectFamilias; The Children's Trust, Miami FL

Recruiting

Natural Helpers and PCIT

Parenting | Child Behavior

United States
University of Manchester
Northern Care Alliance NHS Foundation Trust; National Institute for Health... and other collaborators

Active, not recruiting

SC IL-1Ra in SAH - Phase III Trial (SCIL) (SCIL)

Subarachnoid Hemorrhage

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; National Institute for Health Research, United Kingdom

Recruiting

SDF for the Management of Dental Caries in Children in Primary Dental Care: Protocol for a Feasibility Study

Dental Caries in Children

United Kingdom
Imperial College London
Royal Brompton & Harefield NHS Foundation Trust; National Institute for Health...

Completed

Intelligent Oxygen Therapy During Activities of Daily Living

Hypoxia | COPD | Hyperoxia

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
University of Oxford; National Institute for Health Research, United Kingdom

Completed

The POSA Trial - Positional Therapy for Positional OSA (POSA)

Sleep Apnea, Obstructive | Positional Sleep Apnea

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; National Institute for Health Research, United Kingdom

Completed

Selenium for Musculoskeletal Health

Osteoporosis

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
University of Bristol; National Institute for Health Research, United Kingdom

Unknown

Mesothelioma and Radical Surgery 2 (MARS2)

Mesothelioma

United Kingdom
Royal Devon and Exeter NHS Foundation Trust
Novartis Pharmaceuticals; National Institute for Health Research, United Kingdom

Completed

The Vascular Effects of Vildagliptin in Insulin Resistant Individuals

Insulin Resistance | Microvascular Disease

United Kingdom
Jane Barnes
National Institute for Health Research, United Kingdom

Completed

Antiglucocorticoid Augmentation of antiDepressants in Depression (ADD)

Depression

United Kingdom
Oxford University Clinical Research Unit, Vietnam
Medical Research Council; University of Oxford; Wellcome Trust; Department for...

Recruiting

The Azithromycin and Cefixime Treatment of Typhoid in South Asia Trial (ACT-South Asia Trial) (ACT-South Asia)

Typhoid Fever

Nepal
King's College London
Boston Children's Hospital; Massachusetts Institute of Technology; Guy's and... and other collaborators

Recruiting

Prediction of Adverse Outcome Using Fetal MRI in Pregnancies at Risk of Preterm Birth

Preterm Birth Complication

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
Medical Research Council; National Institute for Health Research, United Kingdom

Recruiting

Gaucherite - A Study to Stratify Gaucher Disease (Gaucherite)

Gaucher Disease, Type III | Gaucher Disease, Type I

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
National Institute for Health Research, United Kingdom; Alexion Pharmaceuticals...

Completed

Characterisation of Adult-Onset Hypophosphatasia

Hypophosphatasia

United Kingdom
University Hospital Southampton NHS Foundation...
Medical Research Council; National Institute for Health Research, United Kingdom

Completed

The Southampton Mealtime Assistance Roll-out Trial (SMART)

Volunteer Mealtime Assistants

United Kingdom
Royal Marsden NHS Foundation Trust
Merck Sharp & Dohme LLC; National Institute for Health Research, United Kingdom

Terminated

A Study of Pembrolizumab And Platinum With Radiotherapy in Cervix Cancer (PAPAYA)

Cervix Cancer

United Kingdom
Anna Griffiths, MRC
Medical Research Council; Wellcome Trust; Department for International Development... and other collaborators

Completed

Reduction of EArly mortaLITY in HIV-infected Adults and Children Starting Antiretroviral Therapy (REALITY)

Human Immunodeficiency Virus

Malawi, Zimbabwe, Kenya, Uganda
University of Cambridge
National Institute for Health Research, United Kingdom; Cambridgeshire and...

Completed

Technology-enhanced Therapy: the SilverCloud Study

Depression

United Kingdom
Hull University Teaching Hospitals NHS Trust
National Institute for Health Research, United Kingdom; University of York; South... and other collaborators

Completed

Feasibility Study of Early Review and Early Cardiac Rehabilitation After Coronary Artery Bypass (FARSTER-I)

Coronary Artery Disease | Quality of Life

United Kingdom
NYU Langone Health
The New York Community Trust; United Hospital Fund

Completed

Intervening With and Improving Care for Patients at Risk for Frequent Hospital Admissions

Hospitalization | Patient Readmission

United States
Manchester University NHS Foundation Trust
Northern Care Alliance NHS Foundation Trust; National Institute for Health... and other collaborators

Completed

Comparing Gamification With Remote Monitoring Against Standard Rehabilitation, for Patients After Arthroscopic Subacromial Decompression Surgery (GAME)

Subacromial Impingement Syndrome | Shoulder Impingement Syndrome

United Kingdom
University of Cambridge
Imperial College London; Cambridge University Hospitals NHS Foundation Trust; Wellcome Trust and other collaborators

Active, not recruiting

PET Imaging of Giant Cell and Takayasu Arteritis (PITA)

Giant Cell Arteritis | Takayasu Arteritis

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
University of Oxford; National Institute for Health Research, United Kingdom; Oxford University Hospitals NHS Trust

Completed

Continuous vs Intermittent Dabrafenib Plus Trametinib in BRAFV600 Mutant Stage 3 Unresectable or Metastatic Melanoma (INTERIM)

Melanoma

United Kingdom
University of Oxford
National Institute for Health Research, United Kingdom; European Commission; Oxford... and other collaborators

Terminated

A Eurosarc Study of Mifamurtide in Advanced Osteosarcoma (MEMOS) (MEMOS)

Osteosarcoma

United Kingdom, Germany, Italy, Netherlands, Norway
Royal Brompton & Harefield NHS Foundation Trust
Liverpool Heart and Chest Hospital NHS Foundation Trust; National Institute...

Unknown

Catheter Ablation Versus Thoracoscopic Surgical Ablation in Long Standing Persistent Atrial Fibrillation (CASA-AF) (CASA-AF)

Persistent Atrial Fibrillation

United Kingdom
Newcastle University
Bristol-Myers Squibb; Institute of Cancer Research, United Kingdom; Newcastle-upon-Tyne... and other collaborators

Completed

Comparison of Imatinib Versus Dasatinib in Patients With Newly-diagnosed Chronic Phase Chronic Myeloid Leukaemia (SPIRIT2)

Myeloid Leukemia, Chronic, Chronic Phase

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
GlaxoSmithKline; University of Cambridge; Royal Brompton & Harefield NHS Foundation... and other collaborators

Completed

Losmapimod in Chronic Obstructive Pulmonary Disease Patients Stratified by Fibrinogen. (EVOLUTION)

Chronic Obstructive Pulmonary Disease

United Kingdom
Yale University
The Hospital for Sick Children; United States Department of Defense; Connecticut...

Completed

Innovation in the Treatment of Persistent Pain in Adults With NF1: Implementation of the iCanCope Mobile Application- Clinical Trial

Chronic Pain | Neurofibromatosis 1

United States
University of Manchester
National Institute for Health Research, United Kingdom; Greater Manchester...

Completed

Youth Metacognitive Therapy Feasibility Trial (YoMETA)

Depression | Anxiety Disorders | Child Mental Disorder

United Kingdom
King's College London
National Institute for Health Research, United Kingdom; South London and Maudsley...

Completed

Electronic Clinical Decision Support for Diabetes and Dysglycaemia in Secondary Mental Healthcare

Diabetes Mellitus | Dysglycemia | Severe Mental Disorder | Staff Attitude

United Kingdom
University of Birmingham
East Kent Hospitals University NHS Foundation Trust; National Institute for...

Active, not recruiting

Accuracy of Glomerular Filtration Rate (GFR) Estimation Using Creatinine and Cystatin C and Albuminuria (eGFR-C)

Chronic Kidney Diseases

United Kingdom
Imperial College London
Cambridge University Hospitals NHS Foundation Trust; University of Manchester; Food Standards Agency, United Kingdom

Completed

Mechanisms Underlying Peanut Allergic Reactions in TRACE Peanut Study Participants: Extension Study (TRACEextension)

Food Hypersensitivity | Peanut Hypersensitivity
Cambridge University Hospitals NHS Foundation Trust
National Institute for Health Research, United Kingdom; Wolfson Brain Imaging...

Recruiting

Quantiative MRI and Myelin-PET for the Assessment of Degenerative Cervical Myelopathy (IMAGE-DCM)

Cervical Spondylosis With Myelopathy | Degenerative Cervical Myelopathy

United Kingdom
King's College London
National Institute for Health Research, United Kingdom; South London and Maudsley...

Completed

High Intensity Interval Training in Severe Mental Illness

Schizophrenia | Bipolar Disorder | Major Depressive Disorder

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College London; National Institute for Health Research, United Kingdom

Completed

Role of Anti-IgE in Severe Childhood Eczema (ADAPT)

Child | Atopic Dermatitis | Atopic Eczema

United Kingdom
Royal Devon and Exeter NHS Foundation Trust
National Institute for Health Research, United Kingdom; University of Exeter

Completed

Predicting Response to Incretin Based Agents in Type 2 Diabetes (PRIBA)

Type2 Diabetes

United Kingdom
East and North Hertfordshire NHS Trust
National Institute for Health Research, United Kingdom; Manuka Doctor UK Ltd

Recruiting

HONEY for the Treatment of POst-Tonsillectomy Pain (HONEY-POT)

Analgesia | Post Surgical Pain

United Kingdom
King's College London
National Institute for Health Research, United Kingdom; South London and Maudsley...

Completed

Group Training for Social Skills in Psychosis (GRASP)

Psychotic Disorders

United Kingdom
Norfolk and Norwich University Hospitals NHS Foundation...
University of East Anglia; Ministry of Defence, United Kingdom

Completed

Pharmacokinetic and PHarmacodynamic Analysis and Evaluation of Teriparatide (PTH 1-34) Between Sexes (PHAB)

Stress Fracture

United Kingdom
Royal Marsden NHS Foundation Trust
Imperial College London; Royal Brompton & Harefield NHS Foundation Trust; Institute... and other collaborators

Recruiting

AI & Radiomics for Stratification of Lung Nodules After Radically Treated Cancer (AI-SONAR)

Lung Cancer | Lung Metastases | Indeterminate Pulmonary Nodules | Second Primary Cancer

United Kingdom
King's College London
King's College Hospital NHS Trust; Guy's and St Thomas' NHS Foundation Trust; National Institute for Health Research, United Kingdom

Suspended

A Psychoeducational Intervention Supporting Patients With an Inherited Cardiac Condition (PISICC)

Cardiomyopathies | Inherited Cardiac Conduction Disorder

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
University of East Anglia; Manchester University NHS Foundation Trust; National...

Not yet recruiting

Co-designing and Evaluating a Real-world Implementation Model for Remote Consultation With Vision Self-testing. (ReVise)

Ophthalmic Disorders
Cambridge University Hospitals NHS Foundation Trust
Juvenile Diabetes Research Foundation; Wellcome Trust; University of Cambridge; National Institute for Health Research, United Kingdom

Completed

Regulatory T Cells in Type 1 Diabetes Patients Treated With IL-2 (DILT1D)

Type 1 Diabetes

United Kingdom
University of the West of England
Royal United Hospital Bath NHS Trust

Completed

Self Soft Tissue Therapy for Fibromyalgia Syndrome

Fibromyalgia Syndrome

United Kingdom
University College, London
University of Cambridge; National Institute for Health Research, United Kingdom and other collaborators

Unknown

Development of an Optimal Antibiotic Regime for Long-term Therapy in Stable Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease (COPD).

United Kingdom
University of Oxford
National Institute for Health Research, United Kingdom; The PATH Malaria Vaccine...

Completed

A Safety and Efficacy Study of Concomitant Administration of ChAd63/MVA ME-TRAP + RTS,S

Plasmodium Falciparum Malaria

United Kingdom
University of Oxford
National Institute for Health Research, United Kingdom; The PATH Malaria Vaccine...

Completed

A Phase I/IIa Study of the Safety, Immunogenicity and Efficacy of FMP2.1/AS01B, an Asexual Blood-Stage Vaccine for Plasmodium Falciparum Malaria

Plasmodium Falciparum Malaria

United Kingdom
Royal Marsden NHS Foundation Trust
Merck Sharp & Dohme LLC; Astex Pharmaceuticals, Inc.; Institute of Cancer Research...

Recruiting

Combination Study of Guadecitabine/ASTX727 and Pembrolizumab (HyPeR)

Non Small Cell Lung Cancer | Castration-Resistant Prostatic Cancer

United Kingdom
University of Southampton
BlueWind Medical; University Hospital Southampton NHS Foundation Trust; National...

Withdrawn

Urinary Catheter 'Fill and Flush' Valve: Safety, Effectiveness, Acceptability and Feasibility Trial

Indwelling Urinary Catheter Users

United Kingdom
University Hospital Southampton NHS Foundation...
Bristol-Myers Squibb; Cancer Research UK; Institute of Cancer Research, United...

Completed

The Addition of Ipilimumab to Carboplatin and Etoposide Chemotherapy for Extensive Stage Small Cell Lung Cancer (ICE)

Extensive Stage Small Cell Lung Cancer

United Kingdom

Clinical Trials Sponsored by The Children's Trust, United Kingdom

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