Search clinical trials for: Abiraterone acetate

Total 3566 results

University of California, San Francisco
Johnson & Johnson; Cougar Biotechnology, Inc.

Completed

Abiraterone Post Ketoconazole for Prostate Cancer

Prostate Cancer

United States
Sidney Kimmel Cancer Center at Thomas Jefferson...
Millennium: The Takeda Oncology Company

Completed

Alisertib, Abiraterone Acetate and Prednisone in Treating Patients With Hormone-Resistant Prostate Cancer

Recurrent Prostate Cancer | Hormone-resistant Prostate Cancer | Adenocarcinoma of the Prostate | Stage IV Prostate Cancer

United States
West China Hospital

Unknown

Docetaxel Versus Abiraterone as First-line Treatment in mCRPC Patients With Intraductal Carcinoma of the Prostate

Prostate Cancer | Castration-resistant Prostate Cancer | Drug
Janssen Pharmaceutical K.K.

Completed

Phase 1 Study of Abiraterone Acetate in Castration-resistant Prostate Cancer

Prostatic Neoplasms

Japan
Janssen Research & Development, LLC

Completed

A Phase 2 Study to Evaluate Safety and Efficacy of Abiraterone in Participants With Prostate Cancer

Prostate Cancer

Japan
University of Southern California
National Cancer Institute (NCI)

Unknown

Abiraterone Acetate and Prednisone With or Without Dasatinib in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer

Recurrent Prostate Cancer | Hormone-resistant Prostate Cancer | Stage IV Prostate Cancer

United States
University of Washington
National Cancer Institute (NCI)

Completed

Abiraterone Prednisone and Hormonal Therapy Before and During Radiation Therapy in Localized Prostate Cancer (RAD1)

Stage II Prostate Cancer | Stage III Prostate Cancer | Adenocarcinoma of the Prostate | Stage IV Prostate Cancer

United States
Icahn School of Medicine at Mount Sinai

Terminated

Abiraterone Acetate Trial in African American Prostate Cancer Patients

Prostate Cancer

United States
Azienda Socio Sanitaria Territoriale degli Spedali...
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano; Niguarda Hospital; San... and other collaborators

Unknown

Activity of Abiraterone Acetate in the Management of Cushing's Syndrome in Patients With Adrenocortical Carcinoma (ABACUS)

Cushing Syndrome | Adrenocortical Carcinoma

Italy
Rutgers, The State University of New Jersey
National Cancer Institute (NCI); AbbVie; Rutgers Cancer Institute of New Jersey

Terminated

Navitoclax and Abiraterone Acetate With or Without Hydroxychloroquine in Treating Patients With Progressive Metastatic Castrate Refractory Prostate Cancer

Prostate Cancer

United States
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Terminated

Dietary Fat Levels and Abiraterone Acetate Uptake in Patients With Metastatic Hormone-Resistant Prostate Cancer

Recurrent Prostate Cancer | Hormone-resistant Prostate Cancer | Adenocarcinoma of the Prostate | Stage IV Prostate Cancer

United States
Johnson & Johnson Pharmaceutical Research & Development...

Approved for marketing

Study of Abiraterone Acetate in Patients With Advanced Prostate Cancer

Urogenital Neoplasms | Genital Neoplasms, Male | Prostate Neoplasms | Genital Diseases, Male

United States, Australia, Hong Kong, Spain, Colombia, Mexico, Poland, Malaysia, Romania, Canada, Greece, Taiwan, Korea, Republic of, New Zealand, Singapore, Brazil, Russian Federation, Czech Republic, Puerto Rico, Thailand, Hungary and more
Aurelius Omlin
University Hospital, Basel, Switzerland; Cantonal Hospital of St. Gallen

Terminated

Abiraterone-Rechallenge Study for CRPC Patients (ABI-RE)

Prostate Cancer

Switzerland
Janssen Scientific Affairs, LLC

Completed

Real-World Study of Enzalutamide and Abiraterone Acetate (With Prednisone) Tolerability (REAAcT)

Prostate Cancer

United States
Centro Nacional de Investigaciones Oncologicas...
Fundación de investigación HM; Institute of Cancer Research, United Kingdom; University... and other collaborators

Completed

SWITCH: Study of the Prednisone to Dexamethasone Change in mCRPC Patients Treated With Abiraterone

Prostate Cancer

Spain
Cancer Research UK

Completed

Abiraterone Acetate in Treating Postmenopausal Women With Advanced or Metastatic Breast Cancer

Breast Cancer

United Kingdom
Astex Pharmaceuticals, Inc.

Completed

A Study of HSP90 Inhibitor AT13387 Alone or in Combination With Abiraterone Acetate

Prostate Cancer

United States, United Kingdom, Spain, Canada
Sanofi

Completed

Cabazitaxel and Abiraterone Acetate in Patients With Metastatic Castrate-Resistant Prostate Cancer

Prostate Cancer

France, United Kingdom, United States
University Hospital, Grenoble

Terminated

F-choline PET in Early Response Assessment for Castration Resistant Prostatic Cancer (PRECHOL)

Castration-resistant Prostate Cancer

France
Janssen Research & Development, LLC

Completed

Bioequivalence Study of Abiraterone Acetate Coated and Uncoated Tablet Formulations in Healthy Male Participants

Healthy

United States
Janssen Pharmaceutica

Withdrawn

Post-marketing Surveillance Study on the Safety and Effectiveness of Abiraterone Acetate Among Adult Filipino Male Patients With Advanced Metastatic Castration Resistant Prostate Cancer

Prostate Neoplasms
Janssen Research & Development, LLC

Completed

A Phase 2 Study to Evaluate Safety and Efficacy of Abiraterone in Participants With Prostate Cancer Who Have Received Docetaxel

Prostate Cancer

Japan
University Health Network, Toronto

Completed

A Correlative Study of Biomarkers of Resistance in Patients With Castrate Resistant Prostate Cancer Treated With Abiraterone

Prostate Cancer (Adenocarcinoma)

Canada
Exelixis

Terminated

Study of Cabozantinib in Combination With Abiraterone in Chemotherapy-Naïve Subjects With Bone-Metastatic Castration-Resistant Prostate Cancer

Prostatic Neoplasms | Prostate Cancer | Castration Resistant Prostate Cancer

United States
Kenneth Pienta, MD
Prostate Cancer Foundation Norway

Withdrawn

A Phase II Neoadjuvant Study of Enzalutamide, Abiraterone Acetate, Dutasteride and Degarelix in Men With Localized Prostate Cancer Pre-prostatectomy

Prostate Cancer | Localized Prostate Cancer

United States
Janssen Research & Development, LLC

Completed

A Study to Assess the Relative Bioavailability of 4 New Abiraterone Acetate Tablet Formulations With Respect to the Current Commercial Abiraterone Acetate Tablet Under Fasted Conditions in Healthy Male Participants

Healthy Volunteers

United States
Janssen-Ortho Inc., Canada

Completed

A Study to Determine the Short-Term Safety of Continuous Dosing of Abiraterone Acetate and Prednisone in Modified Fasting and Fed States to Patients With Metastatic Castration-Resistant Prostate Cancer

Prostate Cancer | Prostate Neoplasms

Canada
Janssen Research & Development, LLC

Completed

An Observational Study of Continuous Oral Dosing of Abiraterone Acetate in Castration-Resistant Prostate Cancer Patients Evaluating Androgens and Steroid Metabolites in Bone Marrow Plasma

Prostate Neoplasms

United States
Janssen Research & Development, LLC

Completed

A Pharmacokinetic Study of Abiraterone Acetate in Patients With Severe Hepatic Impairment Compared to Patients With Normal Hepatic Function

Hepatic Impairment

United States
Cougar Biotechnology, Inc.

Completed

Neo-adjuvant Abiraterone + Luteinizing Hormone-Releasing Hormone (LHRH) Versus LHRH in Prostate Cancer

Prostate Cancer

United States
Cougar Biotechnology, Inc.

Completed

An Safety and Efficacy Study of Abiraterone Acetate in Participants With Advanced Prostate Cancer Who Failed Androgen Deprivation and Docetaxel-Based Chemotherapy

Prostate Neoplasms

United States, United Kingdom
Cougar Biotechnology, Inc.

Completed

Abiraterone Acetate in Castration-Resistant Prostate Cancer Previously Treated With Docetaxel-Based Chemotherapy

Prostatic Neoplasms

United States, Australia, France, United Kingdom, Belgium, Germany, Spain, Canada, Austria, Netherlands, Ireland, Hungary
Janssen Research & Development, LLC

Completed

Abiraterone Acetate Dose-Escalation Study in Hormone Refractory Prostate Cancer

Prostate Neoplasms

United States
Janssen Research & Development, LLC

Completed

A Study to Assess the Effect of Abiraterone (JNJ-589485) on the Pharmacokinetics of Pioglitazone Following Administration of Abiraterone Acetate (JNJ-212082) and Pioglitazone HCl Tablets in Healthy Male Participants

Healthy Volunteers

Belgium
Cougar Biotechnology, Inc.

Completed

A Safety and Efficacy Study of Abiraterone Acetate in Participants With Prostate Cancer Who Have Failed Hormone Therapy

Prostatic Neoplasms

United Kingdom
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study Examining Doses of Abiraterone Acetate in Adult Women With 21-Hydroxylase Deficiency

21-hydroxylase Deficiency

United States
Janssen Research & Development, LLC

Completed

A Study to Assess the Effect of Timing of Food Intake on the Pharmacokinetics of Abiraterone Following Single-Dose Administration of Abiraterone Acetate Tablets in Healthy Caucasian and Japanese Men

Pharmacology

United States
British Columbia Cancer Agency
Janssen Research & Development, LLC

Withdrawn

Anti-Proliferative Effects and Genomic Alterations of Abiraterone Acetate Compared to an Aromatase Inhibitor in Post-menopausal HR+ Operable Breast Cancer

Post-menopausal ER+ Stage I-IIIA Primary Operable Breast Cancer

Canada
Cougar Biotechnology, Inc.

Completed

A Study to Assess the Effect of Abiraterone Acetate in Male Participants With Mild or Moderate Hepatic Impairment Compared to Matched Control Participants With Normal Hepatic Function

Prostate Cancer

United States
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Pharmacokinetics of Abiraterone in Healthy Chinese Male Participants

Healthy

China
Cougar Biotechnology, Inc.

Completed

An Efficacy and Safety Study of Abiraterone Acetate and Prednisone in Participants With Prostate Cancer Who Failed Androgen Deprivation and Docetaxel-Based Chemotherapy

Prostatic Neoplasms | Prostate Cancer

United States, United Kingdom
Janssen Research & Development, LLC

Completed

An Expanded Access Study of Abiraterone Acetate in Patients With Advanced Prostate Cancer Who Have Completed Clinical Study COU-AA-001

Prostate Neoplasms

United Kingdom
Janssen Research & Development, LLC

Completed

A Phase 2 Study to Evaluate Safety and Efficacy of Abiraterone Acetate in Male Participants With Prostate Cancer

Prostate Cancer

United States
Cougar Biotechnology, Inc.

Completed

A Pharmacokinetics Study to Assess Abiraterone Acetate Capsule and Tablet Formulations in Patients With Prostate Cancer

Prostate Neoplasms

United Kingdom, United States
Janssen Research & Development, LLC

Completed

A Drug-Drug Interaction Study of Abiraterone Acetate Plus Prednisone With Dextromethorphan and Theophylline in Patients With Metastatic Castration-Resistant Prostate Cancer

Prostate Neoplasms

United States, Canada
Janssen Research & Development, LLC

Completed

A QT/QTc and Multi-Dose Pharmacokinetic Study of Abiraterone Acetate Plus Prednisone in Patients With Metastatic Castration-Resistant Prostate Cancer

Prostate Neoplasms

United States, Canada
Janssen Research & Development, LLC

Completed

A Comparative Study of Bioavailability of 3 New Abiraterone Acetate Tablets With Current Commercial Tablet

Healthy Participants

United States
Cougar Biotechnology, Inc.

Completed

A Study to Determine the Effect of Food on the Pharmacokinetics of Abiraterone Acetate in Healthy Male Patients

Healthy Volunteers
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effect of Rifampicin on the Pharmacokinetics of Abiraterone in Healthy Male Participants

Healthy

Belgium
Janssen Research & Development, LLC

Completed

A Study to Assess the Effect of Ketoconazole on the Pharmacokinetics of Abiraterone Following Administration of Abiraterone Acetate Tablets in Healthy Adult Men

Healthy Volunteers

Belgium

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