Search clinical trials for: Clinical ethics

Total 59508 results

BioNTech SE

Not yet recruiting

A First-in-human Safety Trial of BNT331 Administered as Single Ascending Doses in Healthy Women and as Multiple Ascending Doses in Women Diagnosed With Bacterial Vaginosis

Bacterial Vaginosis

United States
Kors van der Ent
European Union

Recruiting

Clinical Trial to Evaluate the Efficacy and Safety of Dirocaftor/Posenacaftor/Nesolicaftor in Adults With CF (CHOICES)

Cystic Fibrosis

Netherlands, Spain, France, Germany, Italy, United Kingdom, Portugal, Belgium, Sweden
Xin-Hua Xu

Recruiting

A Prospective, Open-label, Single-center, Single-arm Phase II Clinical Study of Cadonilimab (AK104) Combined With Monotherapy Chemotherapy in Patients With Advanced Non-small Cell Lung Cancer With Negative Driver Genes and Failed Immunotherapy

Non-small Cell Lung Cancer

China
Alcon Research

Not yet recruiting

Clinical Performance of Two Frequent Replacement Silicone Hydrogel Multifocal Contact Lenses

Presbyopia

United States
Shanghai Simnova Biotechnology Co.,Ltd.

Not yet recruiting

F01 in the Treatment of Moderate-to-severe Refractory Systemic Lupus Erythematosus

Lupus Erythematosis

China
Changhai Hospital
Rui Therapeutics

Not yet recruiting

An Exploratory Clinical Study of Anti-CD19 CAR NK Cell (KN5501) in the Treatment of Relapsed/Refractory Immune Nephropathy

Nephropathy
First Affiliated Hospital of Xinjiang Medical University

Not yet recruiting

Clinical Efficacy of Self-adhesive Silicone Gel Waterproof Dressings Versus Conventional Dressings in the Healing of Incisions After Total Joint Arthroplasty (Yes)

Total Joint Arthroplasty | Self-adhesive Silicone Gel Waterproof Dressing | Gauze Dressing
Regeneron Pharmaceuticals

Not yet recruiting

A Study to Learn if 27T51, a Mucin-16 (MUC16) Protein Targeting Immune Cell Therapy, Administered Alone or in Combination is Safe and How Well it Works for Adult Participants With Recurrent or Treatment Resistant Ovarian Cancers

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Primary Peritoneal Carcinoma

United States
Shikai Wu

Recruiting

Development and Application Study of ePRO Software for Managing Cancer Patients Throughout the Treatment Period

Solid Tumor, Adult

China
Ascidian Therapeutics, Inc

Recruiting

Study to Evaluate ACDN-01 in ABCA4-related Retinopathy (STELLAR) (STELLAR)

Stargardt Disease | Stargardt Disease 1 | Juvenile Macular Degeneration | Cone Rod Dystrophy

United States
Shanghai Zhongshan Hospital

Not yet recruiting

Appendicoliths in Acute Complicated Appendicitis Patients With Abscess

Acute Complicated Appendicitis With Abscess
Anhui Provincial Cancer Hospital

Recruiting

An Exploratory Clinical Study of Statins for Improving Chemotherapy and Maintenance in Patients With Ovarian Cancer

Ovarian Cancer

China
University of Alcala

Recruiting

Radiofrequency and Myofascial Pain Syndrome in Postpartum Pelvic Pain (RASDOP)

To be Approved by the Ethics Committee

Spain
Region Skane
Horselvarden Region Ostergotland

Recruiting

Follow Up of an Online Hearing Support for First-time Hearing Aid Users

Hearing Loss | Hearing Disorders | Hearing Impairment

Sweden
Luye Pharma Group Ltd.

Recruiting

Phase II Clinical Trial to Evaluate the Efficacy and Safety of LPM3480392 Injection for Moderate to Severe Pain After Orthopedic Surgery

Pain, Postoperative

China
Dana-Farber Cancer Institute
National Cancer Institute (NCI); American Society of Clinical Oncology

Not yet recruiting

Driving Inclusivity, Validity, and Equity in Research Through Strategic Engagement (DIVERSE) (DIVERSE)

Leukemia | Blood Cancer

United States
AstraZeneca

Recruiting

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of AZD5148 in Healthy Adults

Healthy Participants

United States
AstraZeneca
ICON plc

Not yet recruiting

Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis (MaesTTRo)

Transthyretin Amyloidosis | ATTR-CM | ATTRv-PN | ATTR | ATTR-Mixed | hATTR
Shanghai Zhongshan Hospital

Not yet recruiting

Clinical Significance of Appendicoliths in Elderly Patients Over 80 Years Old Undergoing Emergency Appendectomy

Appendicoliths in Elderly Patients
University of Nottingham
Wellcome Trust

Not yet recruiting

Measuring and Mapping Cognitive Decline After Brain Radiosurgery (CoDeB-Rad)

Quality of Life | Cognitive Decline | Brain Metastases | SRS | Meningiomas | Stereotactic Radiosurgery

United Kingdom
Quiropraxia y Equilibrio

Not yet recruiting

High-intensity Laser Therapy and Stretching Exercises for Chronic Non-specific Neck Pain

Chronic Non-specific Neck Pain

Chile
Claude Bernard University

Not yet recruiting

Influence of Relaxing Breathing Before Each Station of an Objective Structured Clinical Examination (ZENECOS)

Stress | Coping Skills | Performance Anxiety
The First Affiliated Hospital of Zhejiang Chinese...

Recruiting

Effect and Mechanism of Auricular Point Stimulation on Functional Dyspepsia With Sleep Disorder

Functional Dyspepsia | Sleep Disorder

China
University of Bern

Not yet recruiting

Variations of Anonymity, Transparency, and Efficacy in Digital Health Applications (PRIVATE)

Social Anxiety

Switzerland
Institut de Recherches Internationales Servier
Servier Bio-Innovation LLC

Not yet recruiting

Ivosidenib (IVO) Monotherapy and Azacitidine (AZA) Monotherapy in Patients With Hypomethylating Agent (HMA) Naive Myelodysplastic Syndromes (MDS) With an IDH1 Mutation (PyramIDH)

Myelodysplastic Syndromes (MDS) | Hypomethylating Agent (HMA) Naive Myelodysplastic Syndromes (MDS)
Genexine, Inc.
PT Kalbe Genexine Biologics

Recruiting

A Phase 3 Study of Efepoetin Alfa for Treatment of Anemia in Patients With Chronic Kidney Disease on Dialysis

Anemia of Chronic Kidney Disease

Korea, Republic of, Georgia
Ferring Pharmaceuticals

Recruiting

An Exploratory Study to Investigate the Effect of FE 999302 When Given Together With Follitropin Delta During Controlled Ovarian Stimulation (Celestial-1)

Fertility

Czechia, Belgium, Spain
University of Chile
Centro FONDAP de Gerociencia, Salud mental y Metabolismo (GERO); Center for...

Recruiting

Nicotinamide Supplementation Improves Physical Performance in Older Adults at Risk of Falls (NICE-FIT)

Frailty | Fall | Frailty Syndrome | Falls

Chile
Philips Healthcare (Suzhou) Co., Ltd.

Not yet recruiting

Clinical Study of CT 5400 RT for System Validation

Performance and Safety
Mansoura University

Recruiting

Investigate"Clinically" the Effectiveness of Boswellia Based Intracanal Medication Compared to Calcium Hydroxide Ca(OH)2 and Ledermix on the Levels of Bacteria and Inflammatory Cytokines in Root Canals and Periradicular Tissues of Teeth With Apical Periodontitis

Microbial Colonization

Egypt
Castilla-La Mancha Health Service

Not yet recruiting

Clinical Utility of Tight Objectives of Advanced Hybrid Closed-loop Systems Among Type 1 Diabetes Patients (TightT1AHCL) (TightT1AHCL)

Type 1 Diabetes

Spain
Oxford Health NHS Foundation Trust

Recruiting

Self-compassion and Quality of Life After Dementia Diagnosis

Dementia

United Kingdom
Regeneron Pharmaceuticals

Not yet recruiting

A Study of Cemiplimab Plus Chemotherapy Versus Cemiplimab Plus Chemotherapy Plus Other Cancer Treatments for Adult Patients With Operable Non-Small Cell Lung Cancer (NSCLC)

Non-Small Cell Lung Cancer
UK Innovations GP LTD
Lindus Health; Advarra

Recruiting

Using a Novel Skin Tag Removal Device

Achrochordon

United States
AstraZeneca

Recruiting

STEP: Phase IIIb Study of Benralizumab to Step-down Maintenance Therapy in Patients With Severe Eosinophilic Asthma (STEP)

Severe Eosinophilic Asthma

China
Institute of Hematology & Blood Diseases Hospital...

Recruiting

A Prospective Clinical Study of CD3-CD20 Bisspecific Antibody Based Therapy Combined With CD19-CAR T Cells in the Treatment of Relapsed Refractory B-cell Non-Hodgkin Lymphoma

B-cell Non-Hodgkin Lymphoma

China
Dow University of Health Sciences

Recruiting

A Clinical Trial to Compare Lasotronix Alone or in Combination With CPP-ACP to Treat DH

Hypersensitivity | Dentin Sensitivity | Cervical Lesion

Pakistan
Medical University of Vienna

Not yet recruiting

Personalized Shared Eye-care Identification of Age-related Macular Degeneration Using Artificial Intelligence and Telemedicine by Matching Optometrist Office-based Sites With Clinical Supervision (PYRENEES)

Age-Related Macular Degeneration
Henan Cancer Hospital

Not yet recruiting

Clinical Study of SHR-A1921 or SHR-A2009 in Previously Treated Advanced NSCLC

NSCLC

China
French Cardiology Society
Lifetech Scientific (Shenzhen) Co., Ltd.

Recruiting

Post-marketing Clinical Study of the LAMBRE System for Left Auricle Closure (ESCALLE)

Atrial Fibrillation

France
University of Sao Paulo
University of Campinas, Brazil; Faculdade de Medicina do ABC

Recruiting

Use of Botulinum Toxin A in Direct Eyebrow Lift Scar

Skin Scarring | Eyebrow Ptosis

Brazil
Yantai LNC Biotechnology Singapore PTE. LTD.

Not yet recruiting

Clinical Study of 68Ga-LNC1007 Injection PET/CT

Healthy Volunteers | Cancer Patients

Singapore
Zhejiang Provincial People's Hospital
Zhejiang University; Hangzhou RonGu Biotechnology Limited Company

Not yet recruiting

Clinical Study of Cord Blood-Derived CAR-NK Cells in Gastric Cancer and Pancreatic Cancer

Gastric Cancer | Pancreas Adenocarcinoma

China
Merck Sharp & Dohme LLC

Not yet recruiting

A Clinical Study of Efinopegdutide in People With Compensated Cirrhosis Due to Steatohepatitis (MK-6024-017)

Non-alcoholic Fatty Liver Disease | NAFLD | Nonalcoholic Steatohepatitis | Metabolic Dysfunction-associated Steatotic Liver Disease | Metabolic Dysfunction-associated Steatohepatitis
Changhai Hospital
Rui Therapeutics

Not yet recruiting

An Exploratory Clinical Study of CD19 CAR NK Cell Injection for the Treatment of Relapsed/Refractory Autoimmune Diseases

Autoimmune Diseases
Wuhan Union Hospital, China
Wuhan Hamilton Biotechnology Co., Ltd; Guangzhou Hamilton Biotechnology Co....

Recruiting

Phase I Clinical Trial of UC-MSCs in the Treatment of Knee Osteoarthritis

Knee Osteoarthritis

China
Genentech, Inc.

Recruiting

A Study to Evaluate the Effect of Injection Site on PK of Astegolimab in Healthy Subjects

Healthy Volunteers

United States
SpinChip Diagnostics ASA
CTC Clinical Trial Consultants AB; Scandinavian Contract Research Organization

Recruiting

SpinChip Hs-cTnI Determination of the 99th Percentile URL (HEAT-3)

Acute Myocardial Infarction

Sweden
Laure Pittet, MD-PhD

Recruiting

Registry of Vaccine Responses in Immune Compromised Patients (REVAPI)

Immunosuppression

Switzerland
Hong Daqing

Recruiting

Clinical Validation of the Management Process for Renal Anemia in Maintenance Hemodialysis Patients

Anemia of Chronic Kidney Disease

China

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