Search clinical trials for: Diabetic Macular Edema (DME)

Total 8774 results

Ain Shams University

Recruiting

Comparative Study Between IVI of Ranibizumab With and Without Prior ACP in Patients With DME Using OCT-A

Diabetic Macular Edema

Egypt
Astellas Pharma Europe B.V.

Completed

A Study to Evaluate ASP8232 in Reducing Central Retinal Thickness in Subjects With Diabetic Macular Edema (DME) (VIDI)

Diabetes Mellitus | Diabetic Macular Edema

United States
Regeneron Pharmaceuticals
Bayer

Completed

Study of Intravitreal Aflibercept Injection (IAI; EYLEA®; BAY86-5321) in Patients With Diabetic Macular Edema (VISTA DME)

Diabetic Macular Edema

United States
Universidade Federal de Goias

Completed

Comparison of Single Intravitreal Injection of Triamcinolone or Bevacizumab for the Treatment of Diabetic Macular Edema (Tribeva-DME)

Diabetic Macular Edema
Retina Macula Specialists of Miami, LLC
Allergan

Unknown

Increase in Capillary Plexus Density Level Following the Use of Ozurdex for the Treatment of DME (ICOD)

Diabetic Retinopathy | Diabetic Macular Edema | Retinal Ischemia

United States
Allergan

Completed

Study of OZURDEX® in the Treatment of Diabetic Macular Oedema (DME) in Australia - The AUSSIEDEX Study

Diabetic Macular Oedema

Australia
Hyewon Chung
Bayer

Completed

Changes in Inflammatory Biomarkers Including Soluble CD14 and Hyperreflective Foci in DME Patients Treated With Aflibercept (FORESIGHT) (FORESIGHT)

Diabetic Macular Edema

Korea, Republic of
KalVista Pharmaceuticals, Ltd.
Juvenile Diabetes Research Foundation

Completed

A Phase I Single Ascending Dose Study of the Intravitreal Plasma Kallikrein Inhibitor KVD001 in Subjects With DME

Diabetic Macular Edema

United States
Novartis Pharmaceuticals

Completed

A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamic Activity of Intravitreal LKA651 in Patients With Macular Edema

Diabetic Macular Edema | Macular Edema | Neovascular Age-related Macular Degeneration | Retinal Vein Occlusions

Puerto Rico, United States
University of Chicago
Northwestern University; Ann & Robert H Lurie Children's Hospital of Chicago; Howard Brown Health Center and other collaborators

Recruiting

PrEP Optimization Among Women to Enhance Retention and Uptake (POWER Up)

PrEP Uptake

United States
Asan Medical Center

Withdrawn

Efficacy and Safety of Precut-EMR for Resecting of Colonic Polyp

Colonic Polyps

Korea, Republic of
Singapore National Eye Centre
Santen Pharmaceutical Co., Ltd.; Singapore Eye Research Institute

Unknown

Diabetic Macular Edema Asian Response (DEAR) Study: Biomarkers for Response to Aflibercept in Asian Patients With Center Involving DME

Diabetic Macular Edema

Singapore
Technical University of Munich

Unknown

Endoscopic Full-thickness REsection of Residual Colorectal Lesions - The FiRE Study (FiRE)

Adenoma

Germany
Taipei Veterans General Hospital, Taiwan
National Taiwan University Hospital; Chang Gung Memorial Hospital; Kaohsiung...

Completed

Efficacy and Safety of Aflibercept as Mono-therapy in Treat and Extend Regimen for DME Patients in Taiwan

Center-involved Diabetic Macular Edema
Istituto Clinico Humanitas

Not yet recruiting

Efficacy, Safety and Recurrence After Cold-EMR Plus APC for Large Colonic Lesions (EMR+APC)

Colonic Disease

Italy
Regeneron Pharmaceuticals
Bayer

Completed

DME And VEGF Trap-Eye [Intravitreal Aflibercept Injection (IAI;EYLEA®;BAY86-5321)] INvestigation of Clinical Impact (DA VINCI)

Diabetic Macular Edema

United States, Austria, Canada
Sanofi
Regeneron Pharmaceuticals

Completed

Study of Dupilumab for the Treatment of Patients With Prurigo Nodularis, Inadequately Controlled on Topical Prescription Therapies or When Those Therapies Are Not Advisable (LIBERTY-PN PRIME)

Neurodermatitis

France, United States, Argentina, China, Japan, Korea, Republic of, Mexico, Russian Federation
Novartis Pharmaceuticals

Completed

Ranibizumab "Treat and Extend" in Diabetic Macular Edma (OPTIMAL)

Diabetic Macular Edema

Norway
Ministry of Health and Population, Egypt

Unknown

Vitrectomy With Planned Foveal Detachment for Refractory DME With or Without Vitreo-macular Interface Abnormality

Chronic Edema of the Macula
ThromboGenics

Completed

A Study to Evaluate the Safety and Efficacy of THR-317 for the Treatment of Diabetic Macular Oedema (DME)

Diabetic Retinopathy | Macular Edema

Czechia, Slovakia, Hungary
Quark Pharmaceuticals

Completed

PF-04523655 Dose Escalation Study, and Evaluation of PF-04523655 With/Without Ranibizumab in Diabetic Macular Edema (DME) (MATISSE)

Diabetic Retinopathy | Diabetic Macular Edema | Choroidal Neovascularization

United States, Israel, United Kingdom, Belgium, Germany, Poland, Czech Republic
Regeneron Pharmaceuticals
Bayer

Active, not recruiting

Study of a High-Dose Aflibercept in Participants With Diabetic Eye Disease (PHOTON)

Type 2 Diabetes Mellitus | Diabetic Macular Edema | Type 1 Diabetes Mellitus

United States, Puerto Rico, Japan, United Kingdom, Canada, Czechia, Germany, Hungary
Second Affiliated Hospital, School of Medicine,...

Recruiting

Comparison of Restoration in Vitreous Hemorrhage Patients With DME After or Not Removing Inner Limiting Membrane

Vitreous Hemorrhage | Macular Edema Due to Diabetes Mellitus

China
Khyber Teaching Hospital

Recruiting

Comparison of Nebulizers vs Metered-Dose Inhalers With Spacer Device For Treatment Of Childhood Wheeze

Childhood Asthma With Acute Exacerbation

Pakistan
The University of Hong Kong
National University Hospital, Singapore; Korea University; Kyungpook National... and other collaborators

Unknown

To Compare Anti-VEGF Monotherapy With Anti-VEGF and EPM Grid Laser Combination Therapy for Diabetic Macular Edema (END-DME)

Diabetic Macula Edema

China
Pfizer

Withdrawn

A Phase 2 Study Exploring The Safety And Efficacy Of Novel Drug Treatment In Subjects With Diabetic Macular Edema (DME)

Diabetes Mellitus | Diabetic Retinopathy
Radboud University Medical Center
Catharina Ziekenhuis Eindhoven; Maasstad Hospital; Evangelisches Krankenhaus... and other collaborators

Recruiting

Recurrences After Standard EMR vs Plus Thermal Ablation EMR (RESPECT)

Polyps of Colon | Recurrence, Local Neoplasm

Netherlands
Khyber Medical College, Peshawar

Not yet recruiting

Effects OF Acute Aerobic Exercise On Higher Cerebral Functions

Exercise
Novartis Pharmaceuticals

Completed

Observation of Treatment Patterns With Lucentis in Approved Indications (OCEAN)

Neovascular AMD, Visual Impairment Due to DME, Visual Impairment Due to Macular Oedema Secondary to Branch or Central RVO, Visual Impairment Due to CNV

Germany
Bayer
Regeneron Pharmaceuticals

Completed

Study for Collection of Aflibercept Data in Routine Practice (CODEX)

Eye Diseases

France
Baylor College of Medicine

Active, not recruiting

Monopolar Current Cutting Knife vs Bipolar RFA Knife

Gastrointestinal Neoplasms

United States
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of Brolucizumab vs. Aflibercept in Patients With Visual Impairment Due to Diabetic Macular Edema (KESTREL)

Diabetic Macular Edema

United States, Austria, Japan, Australia, Spain, Canada, Israel, Netherlands, Italy, United Kingdom, Portugal, Colombia, Puerto Rico, Argentina
IRCCS Multimedica
AbbVie

Recruiting

OCT and OCT-Angiography Biomarkers of Treatment Response to Dexamethasone Implant in Macular Edema Due to Retinal Vascular Diseases - DME and RVO

Diabetic Macular Edema | Retinal Vein Occlusion | Macular Edema Due to Diabetes Mellitus

Italy
Bayer

Completed

Investigation of the Change of Vision-related Quality of Life in Subjects Treated With Aflibercept According to EU Label for DME. (AQUA)

Macular Edema

Spain, Canada, Switzerland, Portugal, Austria, Poland, Slovakia, United Kingdom, France, Czechia, Germany, Hungary, Italy, Lithuania
Kodiak Sciences Inc

Terminated

A Study to Evaluate the Efficacy, Durability, and Safety of KSI-301 Compared to Aflibercept in Participants With Diabetic Macular Edema (DME) (GLIMMER)

Diabetic Macular Edema

United States, Israel, France, Italy, Hungary, Poland, Puerto Rico, Czechia
Case Western Reserve University
National Institute of Dental and Craniofacial Research (NIDCR)

Completed

Providers Against Cavities in Children's Teeth (PACT)

Dental Caries

United States
Tioga Pharmaceuticals
RTI Health Solutions

Terminated

Asimadoline for the Treatment of Post-Operative Ileus

Post-Operative Ileus

United States
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Brolucizumab vs Aflibercept in Patients With Visual Impairment Due to Diabetic Macular Edema (KINGFISHER)

Diabetic Macular Edema

United States, Hungary, Israel, Slovakia, Puerto Rico
Novartis Pharmaceuticals

Completed

Multiple Dose Safety and Efficacy of LKA651 in Patients With Diabetic Macular Edema

Diabetic Macular Edema

Germany, Turkey, United States, Spain, Puerto Rico
Novartis Pharmaceuticals

Withdrawn

Systemic VEGF Protein Dynamics Following Intravitreal Injections of Ranibizumab Versus Aflibercept in Patients With Visual Impairment Due to Diabetic Macular Edema (TIDE DME)

Visual Impairment Due to Diabetic Macular Edema

Germany
Notal Vision Inc.

Completed

Single In-Clinic Encounter With the Notal Vision Home OCT by DME Patients

Diabetic Retinopathy

Israel
Shanghai BDgene Co., Ltd.
Eye & ENT Hospital of Fudan University

Recruiting

VEGFA-targeting Gene Therapy to Treat Retinal and Choroidal Neovascularization Diseases

Diabetic Macular Edema | Retinal Vein Occlusion | Neovascular Age-related Macular Degeneration

China
AbbVie
AbbVie

Recruiting

RGX-314 Gene Therapy Administered in the Suprachoroidal Space for Participants With Diabetic Retinopathy (DR) Without Center Involved-Diabetic Macular Edema (CI-DME) (ALTITUDE)

Diabetic Retinopathy (DR)

United States
Palmetto Retina Center, LLC

Completed

A Safety and Efficacy Trial of a Treat and Extend Protocol Using Ranibizumab With and Without Laser Photocoagulation for Diabetic Macular Edema (TREX-DME)

Diabetic Macular Edema

United States
Western Sydney Local Health District

Recruiting

ESD for Colorectal LSL Using a Selective Strategy - a Prospective Cohort Study (COVERT)

Colorectal Neoplasm | Endoscopic Mucosal Resection

Australia
Kodiak Sciences Inc

Terminated

A Trial to Evaluate the Efficacy, Durability, and Safety of KSI-301 Compared to Aflibercept in Participants With Diabetic Macular Edema (DME) (GLEAM)

Diabetic Macular Edema

United States, Latvia, Spain, Germany, Italy, Slovakia, Hungary, Puerto Rico
Military University Hospital, Prague
University Hospital Olomouc; Masaryk University

Recruiting

Endoscopic Full Thickness Resection Versus Standard Therapy of the Colorectal Neoplasia

Polyps | Colon Cancer

Czechia
Western Sydney Local Health District

Completed

Cold Snare Polypectomy Versus Endoscopic Mucosal Resection for Colonic Sessile Serrated Polyps (CSP-EMR)

Colorectal Cancer | Adenoma

Australia
Western Sydney Local Health District

Recruiting

Conventional Endoscopic Mucosal Resection Versus Cold Snare Endoscopic Mucosal Resection of Colonic Lateral Spreading Lesions - A Randomised Controlled Trial

Colon Cancer | Colon Adenoma | Adenoma Colon

Australia
McMaster University
Hoffmann-La Roche

Recruiting

Treat & Extend Versus Fixed Dosing With Faricimab for Management of Diabetic Macular Edema: A Pragmatic, Multi-center, Open-label, Randomized, Controlled Trial (INSITE-DME)

Diabetic Macular Edema

United States, Australia, Canada, United Kingdom

Search clinical trials for: Diabetic Macular Edema (DME)

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Liberia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations