Search clinical trials for: N-MYC Amplification

Total 282 results

Clovis Oncology, Inc.

Terminated

A Study to Assess the Efficacy and Safety of the VEGFR-FGFR Inhibitor, Lucitanib, Given to Patients With Advanced/Metastatic Lung Cancer and FGF, VEGF, or PDGF Related Genetic Alterations

Small Cell Lung Cancer | Non-Small Cell Lung Cancer | NSCLC | Lung Cancer | Metastatic Lung Cancer | SCLC | Stage IV Lung Cancer | Advanced Lung Cancer | Squamous Non-Small Cell Lung Cancer

United States, Italy, Germany, France, Spain
Novartis Pharmaceuticals

Completed

LEE011 for Patients With CDK4/6 Pathway Activated Tumors (SIGNATURE) (SIGNATURE)

Tumors With CDK4/6 Pathway Activation

United States
Institute of Hematology & Blood Diseases Hospital

Unknown

a Clinical Trial of Efficacy and Safety of the Holistic Treatment of Young High-risk Multiple Myeloma Patients

Multiple Myeloma | Plasma Cell Leukemia | Extramedullary Plasmacytoma | Loss of Chromosome 17p | t(14;16) | t(4;14) | Complex Karyotype | T(14;20) | 1Q21 Amplification

China
Novartis Pharmaceuticals

Terminated

BGJ398 for Patients With Tumors With FGFR Genetic Alterations (CBGJ398XUS04)

Solid Tumor | Hematologic Malignancies

United States
Peking University

Unknown

Afatinib in Previously Treated ESCC With EGFR Overexpression or EGFR Amplification (ESCC-A01)

Esophageal Squamous Cell Carcinoma

China
University Hospital, Brest

Unknown

Evaluation of Pertuzumab-Trastuzumab and Taxane in the Standard Treatment of Metastatic Breast Cancer (EPTTCSM)

Breast Neoplasms | HER-2 Gene Amplification

France
Samsung Medical Center

Completed

Single-arm Study of Selumetinib in Combination With Docetaxel, in Advanced Gastric Adenocarcinoma Patients With Low/High MEK Signature, RAS Mutation or RAS Amplification as a Second-line Chemotherapy

Gastric Adenocarcinoma

Korea, Republic of
Duke University
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Performance of Nucleic Acid Amplification Tests for the Detection of NG and CT (pNAAT)

Sexually Transmitted Infections | Chlamydia Trachomatis Infection | Neisseria Gonorrhoeae Infection

United States
University of Chicago
Novartis

Terminated

BGJ398 in Treating Patients With FGFR Positive Recurrent Head and Neck Cancer

Head and Neck Squamous Cell Carcinoma | Recurrent Head and Neck Carcinoma | Human Papillomavirus Infection | Recurrent Oropharyngeal Squamous Cell Carcinoma | FGFR Gene Amplification | FGFR1 Gene Amplification | FGFR2 Gene Amplification | FGFR2 Gene Mutation | FGFR3 Gene Mutation | Recurrent Nasopharynx...

United States
University of Cagliari

Unknown

Evaluation of Accuracy of One-Step Nucleic Acid Amplification (OSNA) in Diagnosis of Lymph Node Metastases of Papillary Thyroid Carcinoma

Papillary Thyroid Cancer | Lymph Node Metastases

Italy
Children's Hearing Evaluation and Amplification...

Unknown

An 'Off-the-shelf' Assistive Listening Device: Normal-hearing Children.

Auditory Processing Disorder

United Kingdom
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Withdrawn

Biomarkers in Tissue Samples From Patients Who Have Undergone Neck Dissection for Oral Cancer

Head and Neck Cancer

United States
Duke University
Argos Therapeutics

Terminated

RNA Extraction and Amplification From Biopsy Specimens in Subjects With Metastatic Renal Cell Carcinoma (AGS-NTS-017)

Metastatic Renal Cell Carcinoma | Genitourinary Cancer (Bladder, Prostate or Testicular)

United States
Shanghai Mental Health Center

Unknown

Transcranial Alternating Current Stimulation (tACS) for Cognitive Impairments in Patients With Schizophrenia

Schizophrenia

China
Fondazione del Piemonte per l'Oncologia

Unknown

Study of Trastuzumab-emtansine in Patients With HER2-positive Metastatic Colorectal Cancer Progressing After Trastuzumab and Lapatinib. (RESCUE)

Metastatic Colorectal Cancer

Italy
Centers for Disease Control and Prevention
Evandro Chagas Institute of Clinical Research

Completed

Validation of RealAmp Method for the Diagnosis of Malaria in Endemic Areas of Brazil

Malaria Diagnosis

Brazil
Samsung Medical Center

Terminated

Phase II, Single-arm Study of AZD1775 Monotherapy in Relapsed Small Cell Lung Cancer Patients With MYC Family Amplification or CDKN2A Mutation Combined With TP53 Mutation

Small Cell Lung Cancer

Korea, Republic of
Samsung Medical Center
AstraZeneca

Terminated

Vistusertib (AZD2014) Monotherapy in Relapsed Small Cell Lung Cancer Patients Harboring RICTOR Amplification ([SUKSES-D])

Small Cell Lung Cancer

Korea, Republic of
Rennes University Hospital

Completed

One-step Nucleic Acid Amplification for Detecting Lymph Node Metastasis of Head and Neck Squamous Cell Carcinoma (OSNA-ORL)

cN0 Oral Squamous Cell Carcinomas

France
University of Sao Paulo General Hospital

Unknown

Hearing Aid Impact on Chronic Tinnitus Patients Evaluated by Resting State PET.

Chronic Tinnitus

Brazil
Novartis Pharmaceuticals

Withdrawn

Study of Oral cMET Inhibitor INC280 in Chinese Patients With EGFR Wild-type Advanced Non-small Cell Lung Cancer (NSCLC)

Carcinoma | Non-Small-Cell Lung Cancer
Daping Hospital and the Research Institute of Surgery...

Completed

Combination of Metformin With Gefitinib to Treat NSCLC (CGMT)

NSCLC | Advanced Cancer | EGFR Gene Amplification | Stage IV NSCLC | Stage IIIB NSCLC

China
Tariq Yehia

Completed

Efficiency of Triple Antibiotic Paste, Ciprofloxacin/Propolis, Ciprofloxacin/Metronidazole, Propolis/Metronidazole Combinations on Revascularization Process of Immature Necrotic Maxillary Incisors of Patients 8-18 Years Old.

Dental Pulp Necrosis | Root Canal Infection | Periapical Abscess
Joanne Jeter
National Cancer Institute (NCI); Merck Ltd.

Withdrawn

Pembrolizumab and Imatinib in Patients With Locally Advanced/Metastatic Melanoma With c-KIT Mutation/Amplification

Stage IV Skin Melanoma | Stage IIIB Skin Melanoma | Stage IIIC Skin Melanoma | Stage IIIA Skin Melanoma
First People's Hospital of Hangzhou

Completed

T790M Mutation on ctDNA in Patients With NSCLC After EGFR-TKI Failure

Non-small Cell Lung Cancer Stage III | Non-Small-Cell Lung Cancer Metastatic

China
University of Michigan

Completed

Impact of Physical Activity for Chronic Pelvic Pain (IPA-CPP)

Pelvic Pain

United States
First People's Hospital of Hangzhou

Completed

EGFR Mutations on ctDNA in Patients With Advanced NSCLC

Non-small Cell Lung Cancer Stage III | Non-Small-Cell Lung Cancer Metastatic

China
Samsung Medical Center

Completed

The Pilot Study Evaluate the Safety and Efficacy of Sirolimus in Patients With PIK3CA Mutation and/or PIK3CA Amplification Refractory Solid Tumors

Solid Tumor

Korea, Republic of
Johns Hopkins University
Boston Medical Center

Completed

Evaluation of Non-Inferiority of Two Fast Follower Nucleic Acid Amplification Tests (FIND)

Tuberculosis

United States
Peking University People's Hospital

Unknown

Assessment of LTP-like Pain Amplification in Chronic Low Back Pain Patients

Low Back Pain
AbbVie (prior sponsor, Abbott)

Completed

Study of ABT-700 in Subjects With Advanced Solid Tumors

Advanced Solid Tumors
Massachusetts General Hospital

Completed

A Novel Approach to Methicillin-resistant Staphylococcus Aureus (MRSA) Screening of Colonized Patients

MRSA Colonization

United States
Fondazione Ricerca Traslazionale

Unknown

Crizotinib in Pretreated Metastatic Non-small-cell Lung Cancer With MET Amplification or ROS1 Translocation (METROS) (METROS)

Carcinoma, Non-Small-Cell Lung

Italy
ArQule, Inc. (a wholly owned subsidiary of Merck...

Completed

Phase 1 Dose Escalation Study of ARQ 092 in Adult Subjects With Advanced Solid Tumors and Recurrent Malignant Lymphoma

Solid Tumor | Tumor | Malignant Lymphoma

United States
National Cancer Institute (NCI)

Completed

Amplification of Merkel Cell Polyomavirus From Skin Swabs

Polyomavirus

United States
EarLens Corporation

Completed

The EarLens Contact Hearing Device (CHD) Spectrum Study (Spectrum)

Hearing Loss, Sensorineural

United States
Merrimack Pharmaceuticals

Terminated

A Study of MM-111 and Paclitaxel With Trastuzumab in Patients HER2 Positive Carcinomas of the Distal Esophagus, Gastroesophageal (GE) Junction and Stomach

Stomach Cancer | Gastroesophageal Junction Cancer | HER-2 Gene Amplification | Esophagus Cancer

United States
University of North Carolina, Chapel Hill
Foundation of Hope, North Carolina

Completed

Study of Lurasidone in Treating Antipsychotic Naive or Quasi-Naive Children and Adolescents

Schizophrenia | Schizoaffective Disorder | Schizophreniform Disorder | Autistic Disorder | Child Development Disorders, Pervasive | Psychosis NOS | Bipolar I Disorder | Asperger Syndrome | Bipolar II Disorder | Severe Major Depression With Psychotic Features | Mood Disorder NOS | Single Episode Major Depression... and other conditions

United States
University Hospital, Strasbourg, France

Unknown

Feasibility Study of Preimplantation Genetic Diagnosis for Single-gene Disorders

Preimplantation Diagnosis

France
University Hospital Tuebingen
University Hospital of Cologne

Completed

Amplification and Selection of Antimicrobial Resistance in the Intestine (ASARI)

Acute Leukaemia

Germany
University of Pennsylvania

Completed

Benzocaine Versus Placebo Spray for Pain Relief at Hysterosalpingogram

Analgesia | Pain Relief

United States
Federal University of São Paulo
Federal University of Minas Gerais

Completed

Effectiveness of Two Therapeutic Approaches in Female Teachers With Voice Disorders

Voice Disorders

Brazil
Novartis Pharmaceuticals

Completed

Dovitinib for Patients With Tumor Pathway Activations Inhibited by Dovitinib (SIGNATURE)

Tumor Pathway Activations Inhibited by Dovitinib

United States
AstraZeneca

Terminated

Efficacy and Safety of AZD4547 Versus Paclitaxel in Patients With Advanced Gastric or Gastro-oesophageal Cancer (SHINE)

Gastric Cancer | Gastro-oesophageal Junction Cancer

Bulgaria, Czech Republic, Italy, Korea, Republic of, Spain, United Kingdom, Hungary, Romania, Ukraine, Belgium, Canada, Germany, Taiwan, India, Japan, France
Samsung Medical Center

Completed

Study to Evaluate the Safety and Efficacy of Everolimus, in Subjects With PIK3CA Amplification, PTEN Loss and PIK3CA Mutation Refractory Solid Tumors

Solid Tumor

Korea, Republic of
Alexandru Eniu
Iuliu Hatieganu University of Medicine and Pharmacy

Completed

BRCA1 and BRCA2 Mutation in Romanian Population: a Study of Genotype - Phenotype Correlation at Diagnosis With Prospective Disease Outcome and Survival

To Determine the Prevalence, Penetrance of BRCA1 and BRCA2 Mutations in Romanian Womens With Breast or Ovarian Cancer

Romania
Sun Yat-sen University
307 Hospital of PLA; Fudan University; West China Hospital; Tongji Hospital; Second... and other collaborators

Completed

Trastuzumab Plus Docetaxel and Capecitabine For First Line Treatment of Her2-Positive Advanced Gastric Cancer

Stomach Neoplasms | ERBB2 Gene Amplification | Neoplasms Metastasis

China
University of Regensburg

Completed

Hearing Aids With "Notched Amplification" for the Treatment of Chronic Tinnitus (NoA-Tin)

Tinnitus

Germany
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Studying Biomarkers in Samples From Younger Patients With Wilms Tumor

Kidney Cancer
George Washington University

Completed

Validation of a Simple and Cost-Effective Nucleic Acid Test for HIV Detection

HIV Infections | HIV

United States

Search clinical trials for: N-MYC Amplification

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