Search clinical trials for: Second line chemotherapy

Total 32853 results

National Cancer Institute, Naples

Terminated

The DISTAL-2 Study: Docetaxel Alone or in Combination in Second-line Treatment of Advanced Non Small-Cell Lung Cancer (DISTAL-2)

Advanced Non-Small Cell Lung Cancer

Italy
National Cancer Institute, Naples

Completed

MITO-6: Capecitabine in Platinum Resistant Ovarian Cancer

Ovarian Cancer

Italy
National Cancer Institute, Naples

Completed

BREAST-10: Three-weekly Versus Weekly First-line Chemotherapy for Metastatic or Locally Advanced Breast Cancer (BREAST-10)

Breast Cancer

Italy
Bristol-Myers Squibb

Completed

Ph II Trial of a Novel Anti-angiogenic Agent in Combination With Chemotherapy for the Second-line Treatment of Metastatic Colorectal Cancer

Colorectal Cancer (CRC)

United States, Argentina, Italy
Centro Nacional de Investigaciones Oncologicas...
Apices Soluciones S.L.; Hospital Universitario de Fuenlabrada; Grupo Hospital...

Completed

Study of Individualized Therapies Selection for Patients With Metastatic Colorectal Carcinoma According to the Therapeutic

Metastatic Disease | Adenocarcinoma of Rectum | Adenocarcinoma of Colon

Spain
Pfizer

Completed

A Randomized Trial Of PF-00299804 Taken Orally Versus Erlotinib Taken Orally For Treatment Of Advanced Non-Small Cell Lung Cancer That Has Progressed After One Or Two Prior Chemotherapy Regimen

Non-small Cell Lung Cancer

United States, Taiwan, Korea, Republic of, Australia, Brazil, Spain, United Kingdom, Singapore, Canada, Hong Kong, Poland, Puerto Rico
Peking University

Completed

Trial of ABI-007 Plus S-1 as Second-line Chemotherapy in Advanced Gastric Cancer Patients

Gastric Adenocarcinoma

China
Betta Pharmaceuticals Co., Ltd.

Unknown

Sequential Icotinib Plus Chemotherapy Versus Icotinib Alone as First-line Treatment in Stage IIIB/IV Lung Adenocarcinoma

Adenocarcinoma | EGFR Positive Non-small Cell Lung Cancer

China
Gruppo Oncologico del Nord-Ovest

Terminated

Second-Line Combination Chemotherapy With or Without Bevacizumab in Treating Patients With Metastatic Colorectal Cancer Who Have Received First-Line Chemotherapy and Bevacizumab (BEBYP)

Colorectal Cancer

Italy
European Lung Cancer Working Party

Completed

A Phase II Study of Doxorubicin, Cyclophosphamide and Vindesine With Valproic Acid in Patients With Refractory or Relapsing Small Cell Lung Cancer After Platinum Derivatives and Etoposide

Small Cell Lung Carcinoma

Belgium
UNICANCER
GlaxoSmithKline

Completed

Evaluating Lapatinib + Capecitabine in Patients Aged 70 and Over With HER2 Metastatic Breast Cancer. (GERICO09)

Metastatic Breast Cancer | 70 Years Old Patients and Over | After One Line of Chemotherapy With Trastuzumab

France
Mebiopharm Co., Ltd

Unknown

Study of MBP-426 in Patients With Second Line Gastric, Gastroesophageal, or Esophageal Adenocarcinoma

Gastric Adenocarcinoma | Esophageal Adenocarcinoma | Gastroesophageal Junction Adenocarcinoma

United States, Georgia
Hoffmann-La Roche

Completed

THOR Study: A Study of Continued Herceptin (Trastuzumab) in Combination With Second Line Chemotherapy in Patients With HER2 Positive Metastatic Breast Cancer.

Breast Cancer

Italy
Si-Yu Wang

Completed

Erlotinib Versus Pemetrexed as Second-Line Therapy in Treating Patients With Advanced Lung Adenocarcinoma

Lung Cancer

China
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Plus Dexrazoxane in Treating Patients With Newly Diagnosed Nonmetastatic Osteosarcoma

Sarcoma | Cardiac Toxicity

United States, Canada, Netherlands, Puerto Rico, Switzerland, Australia
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome

Leukemia

United States, Australia, Canada
Pharmacyclics LLC.

Terminated

Study of the Effect on Non-small Cell Lung Cancer of the Investigational Drug Motexafin Gadolinium When Used in Combination With Docetaxel (Taxotere)

Lung Cancer

United States, Canada, Russian Federation, Serbia
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Terminated

High-Dose Cholecalciferol in Treating Patients Receiving Combination Chemotherapy and Bevacizumab as First-Line Therapy For Metastatic Colorectal Cancer

Stage IV Colon Cancer | Stage IV Rectal Cancer

United States
National Cancer Institute (NCI)

Terminated

Rebeccamycin Analog as Second-Line Therapy in Treating Patients With Limited-Stage or Extensive-Stage Small Cell Lung Cancer That Relapsed After Previous First-Line Chemotherapy

Extensive Stage Small Cell Lung Cancer | Recurrent Small Cell Lung Cancer | Limited Stage Small Cell Lung Cancer

United States
China Association of Osteosarcoma Chemotherapy

Unknown

A Clinical Trial on Efficacy and Safety for Lobaplatin and Gemcitabine in Combination With Docetaxel in the Second-line Treatments on Advanced Osteosarcoma

Lobaplatin and Gemcitabine in Combination, Second-line Treatments on Advanced Osteosarcoma
ArQule, Inc. (a wholly owned subsidiary of Merck...

Withdrawn

A Study of ARQ 197 Versus Investigator's Choice of Second-Line Chemotherapy in Patients With Locally Advanced or Metastatic Gastric Cancer Who Have Progressive Neoplastic Disease Following Treatment With One Prior Chemotherapy Regimen

Gastric Cancer
Facet Biotech
National Cancer Institute (NCI)

Unknown

Combination Chemotherapy With or Without Monoclonal Antibody Therapy in Treating Patients With Refractory or Relapsed Acute Myelogenous Leukemia

Leukemia

United States, Canada, Netherlands, Belgium, Germany, United Kingdom, France
Velindre NHS Trust

Unknown

Combination Chemotherapy With or Without Cetuximab as First-Line Therapy in Treating Patients With Metastatic Colorectal Cancer

Colorectal Cancer

United Kingdom, Ireland
Children's Oncology Group
National Cancer Institute (NCI); Children's Cancer Group

Completed

Chemotherapy Followed by Radiation Therapy in Treating Young Patients With Newly Diagnosed Hodgkin's Disease

Lymphoma | Cardiac Toxicity

United States, Australia, Canada
Sun Yat-sen University
Eli Lilly and Company; Hoffmann-La Roche

Unknown

Avastin+ GemAOD As First-Line Treatment in NK/T Cell Lymphoma

Extranodal NK/T-cell Lymphoma, Nasal Type

China
Istituto Scientifico H. San Raffaele

Unknown

Study of Blood and Tissue Samples in Predicting Response to Second-Line Therapy Using Erlotinib Hydrochloride or Chemotherapy in Patients With Advanced Non-Small Cell Lung Cancer

Lung Cancer

Italy
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Chemotherapy in Treating Children With Down Syndrome and Myeloproliferative Disorder, Acute Myelogenous Leukemia, or Myelodysplastic Syndrome

Myelodysplastic Syndromes | Leukemia | Myelodysplastic/Myeloproliferative Neoplasms

United States, Canada, Puerto Rico, Australia, Netherlands, New Zealand, Switzerland
Samsung Medical Center

Unknown

Trial of XELIRI/FOLFIRI + Simvastatin Followed by Simvastatin Maintenance in Metastatic Colorectal Cancer

Colorectal Cancer

Korea, Republic of
Armando Santoro, MD

Terminated

Study of Oral Vorinostat in Combination With Topotecan in Patients With Chemosensitive Recurrent SCLC

Small Cell Lung Cancer

Italy
Washington University School of Medicine
National Cancer Institute (NCI)

Completed

Amifostine, Chemotherapy, and Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer

Lung Cancer | Radiation Toxicity | Drug/Agent Toxicity by Tissue/Organ

United States
Hebei Tumor Hospital

Unknown

A Study of Raltitrexed Plus Docetaxel Versus Docetaxel as Second-line Chemotherapy in Subjects With Gastric Cancer

Gastric Cancer

China
Samsung Medical Center

Completed

Sunitinib + Docetaxel as Second-line Treatment in Gastric Cancer

Advanced Gastric Cancer

Korea, Republic of
Pfizer

Terminated

Sunitinib Plus Prednisone In Patients With Metastatic Castration-Resistant Prostate Cancer After Failure Of Docetaxel Chemotherapy (SUN 1120)

Prostatic Neoplasms

United States, Canada, Spain, Belgium, Finland, Italy, Korea, Republic of, Poland, Portugal, Slovakia, Sweden, Denmark, Taiwan, China, Australia, Germany, Israel, United Kingdom, Brazil, France, Czech Republic, Peru
AIO-Studien-gGmbH
iOMEDICO AG

Terminated

Study to Evaluate the Effects of Panitumumab if Combined With Chemotherapy for 2nd Treatment of Colorectal Cancer (VOXEL)

Colorectal Neoplasms

Germany
AIO-Studien-gGmbH

Terminated

Study to Evaluate the Effects of Sorafenib if Combined With Chemotherapy (FOLFOX6 or FOLFIRI) in the Second-Line Treatment of Colorectal Cancer (FOSCO)

Colorectal Neoplasms

Germany
Technical University of Munich

Terminated

Everolimus in Treating Older Patients With Mantle Cell Lymphoma Previously Treated With First-Line or Second-Line Chemotherapy

Lymphoma

Germany
Chinese University of Hong Kong

Completed

Intermittent Versus Continuous Tarceva Study

Metastatic Colorectal Cancer

Hong Kong
Taiho Pharmaceutical Co., Ltd.
Daiichi Sankyo Co., Ltd.

Completed

Phase II/III Trial of CPT-11/5-FU/l-LV Versus CPT-11/TS-1 as Second Line Chemotherapy of Unresectable Colorectal Cancer

Colorectal Cancer

Japan
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Individualized Exercise Programs for Patients Receiving Chemotherapy for Newly Diagnosed Acute or Relapsed Myeloid Leukemia or Lymphoblastic Leukemia

Depression | Leukemia | Fatigue | Psychosocial Effects of Cancer and Its Treatment | Musculoskeletal Complications

United States
Gruppo Italiano per lo studio dei Carcinomi dell...
Hospira, now a wholly owned subsidiary of Pfizer

Completed

Second Line Chemotherapy for Advanced Pancreatic Cancer (SLAP)

Pancreatic Adenocarcinoma

Italy
Samsung Medical Center

Completed

Second-line Therapy Versus Supportive Care for Pretreated Advanced Gastric Cancer

Advanced Gastric Cancer

Korea, Republic of
Peking University

Unknown

mFOLFIRI Combine With Nimotuzumab Second Line Chemotherapy for Squamous-cell Carcinoma of the Esophagus

Advanced Esophageal Carcinoma

China
Korean South West Oncology Group

Unknown

A Phase II Clinical Trial of Docetaxel, Oxaliplatin Combination Chemotherapy in Patients With Stage IIIB/IV Non-adenocarcinoma, Non-small Cell Lung Cancer (NSCLC) as Second-line Treatment

Carcinoma, Non-Small-Cell Lung | Carcinoma, Large Cell | Carcinoma, Squamous

Korea, Republic of
Japan Clinical Cancer Research Organization
Taiho Pharmaceutical Co., Ltd.

Completed

Second Line Chemotherapy for S-1 Refractory Advanced Gastric Cancer

Gastric Cancer

Japan
Oncozyme Pharma Inc.

Completed

A Safety Study of Pentamidine in Patients With Metastatic Colon Cancer Undergoing Standard Chemotherapy as Second-line and/or Third-line Treatment

Colorectal Cancer

Canada
Hellenic Oncology Research Group
University Hospital of Crete

Completed

Irinotecan Plus Cisplatin vs Pemetrexed Plus Cisplatin as 2nd Line in NSCLC Stage IIIB/IV

Non Small Cell Lung Cancer

Greece
Roswell Park Cancer Institute

Completed

Chemotherapy, Radiation Therapy, and Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Neuroblastoma | Graft Versus Host Disease

United States
Associacio catalana per a la recerca oncologica...
Amgen

Unknown

A Clinical Trial of Panitumumab in Combination With FOLFIRI Chemotherapy as Second Line Treatment in Subjects With Metastatic Colorectal Cancer Expressing Wild-type KRAS and Who Had Progressed ≥ 6 Months After the Last Dose of the First Line Chemotherapy (ACTIVE)

Metastatic Colorectal Cancer

Spain
Fudan University

Unknown

Gemcitabine,Vincristine and Cisplatin as Second Line Combination Therapy in Patients With Sarcoma (GVPS)

Sarcoma | Chemotherapy

China
AGO Study Group
Essex Pharma GmbH; MedServ. GmbH, Wiesbaden

Completed

Combination Chemotherapy Consisting of Pegylated Liposomal Doxorubicin and Carboplatin in Malignant Gynecologic Tumours

Cervical Cancers | Cancer of the Ovary Treated as 2nd Line Therapy | Muellerian Mixed Tumours | Tumours of the Uterus | Non-Epithelial Ovarian Tumours

Germany

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