Search clinical trials for: Single Center

Total 127881 results

James P. Rathmell, MD
New York University; National Institute of Neurological Disorders and Stroke... and other collaborators

Recruiting

EPPIC-Net: Novaremed Painful Diabetic Peripheral Neuropathy ISA (EN21-01)

Painful Diabetic Neuropathy

United States
Vertex Pharmaceuticals Incorporated
CRISPR Therapeutics

Recruiting

Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease

Hematologic Diseases | Genetic Diseases, Inborn | Sickle Cell Disease | Hemoglobinopathies | Sickle Cell Anemia | Thalassemia | Beta-Thalassemia

United States, Italy, Germany, Saudi Arabia
James P. Rathmell, MD
New York University; National Institute of Neurological Disorders and Stroke... and other collaborators

Recruiting

EPPIC-Net: Platform Protocol to Assess Treatments for Painful Diabetic Peripheral Neuropathy

Painful Diabetic Neuropathy

United States
Technische Universität Dresden
Roche Pharma AG

Recruiting

A Single-arm Trial of Atezolizumab/Platinum/Etoposide for the Treatment of Advanced Large-cell Neuroendocrine Cancer of the Lung (LCNEC-ALPINE)

Large Cell Neuroendocrine Carcinoma of the Lung

Germany
Florida International University

Recruiting

Single and Combined Effects of Behavioral, Academic, and Medication Treatments for ADHD in the Classroom

ADHD

United States
The First Hospital of Jilin University

Recruiting

A Prospective, Single Center Clinical Study of Toripalimab Combined With FLOT Regimen for Perioperative Treatment of PD-L1 Positive Locally Advanced Resectable Gastric Cancer or Gastroesophageal Junction Adenocarcinoma (GEJ)

PD-L1 Positive Locally Advanced Patients With Resectable Gastric Cancer

China
Peking Union Medical College

Recruiting

Efficacy and Safety of Furmonertinib in Patients With EGFR Mutations in Advanced NSCLC With Brain Metastases: A Single-center, Open-label, Phase II Trial（iFORCE）

NSCLC | Brain Metastases | Furmonertinib | EGFR-mutation

China
Renmin Hospital of Wuhan University

Recruiting

Validation of an AI-based Biliopancreatic EUS Navigation System for Real-time Quality Improvement: A Prospective, Single-center, Randomized Controlled Trial

Artificial Intelligence | Bile Duct Diseases | Pancreatic Disease | Endoscopic Ultrasonography

China
AstraZeneca
Parexel

Recruiting

AZD7798 Safety, Tolerability, and Pharmacokinetics After a Single Ascending and Repeat Dose Administrations to Healthy Subjects, and Patients With Crohn's Disease

Healthy Subjects | Crohns Disease

United Kingdom
Harvard University

Recruiting

Digital Single Session Intervention for Youth Mental Health

Depression | Stress | Anxiety | Conduct Disorder

United States
ImmunoGen, Inc.
GOG Foundation

Recruiting

Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Ovarian, Fallopian Tube, or Peritoneal Cancer (GLORIOSA)

Ovarian Cancer | Fallopian Tube Cancer | Peritoneal Cancer

United States, Korea, Republic of, Spain, Australia, Canada, United Kingdom, Italy, Czechia, Philippines, Israel, Belgium
Johns Hopkins University
National Institute of Mental Health (NIMH)

Recruiting

Virtual Group Psychoeducational Discussions With Spanish-Speaking Mothers of Infants in Pediatric Primary Care

Postpartum Depression | Postpartum Anxiety

United States
Jiangsu Alphamab Biopharmaceuticals Co., Ltd

Recruiting

Study of KN046 in Subjects With Advanced Non-Small Cell Lung Cancer

Advanced Non-small Cell Lung Cancer

China
Children's Hospital Medical Center, Cincinnati
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

Evaluating the Neurophysiologic and Clinical Effects of Single Dose Drug Challenge

Fragile X Syndrome

United States
Amgen

Recruiting

Single and Multiple Ascending Dose Study to Evaluate AMG 786 in Healthy Participants and Participants With Obesity

Obesity

United States
Sun Yat-sen University

Recruiting

Envafolimab Plus Chemoradiotherapy for Locally Advanced NPC, a Prospective, Single Armed Phase II Trial.

Induction Chemotherapy | Locally Advanced Nasopharyngeal Carcinoma | PD-L1 | Envafolimab

China
Eli Lilly and Company

Recruiting

A Single-Ascending and Repeated Dose Study of LY3849891 in Participants With Nonalcoholic Fatty Liver Disease

Non-Alcoholic Fatty Liver Disease

United States, Japan
UroGen Pharma Ltd.

Recruiting

A Phase 1 Dose-escalation Study of UGN-301 in Patients With Recurrent Non-muscle Invasive Bladder Cancer (NMIBC)

Bladder Cancer | Non-muscle Invasive Bladder Cancer | Urothelial Carcinoma Bladder | NMIBC | Urothelial Carcinoma Recurrent | Carcinoma in Situ of Bladder

United States, Italy, Spain
China National Center for Cardiovascular Diseases

Recruiting

Antithrombotic Strategy Based on Clinical Events and 4D-CT for Patients After TAVR

Transcatheter Aortic Valve Replacement | Antithrombotic Therapy | Bioprosthetic Valve Thrombosis

China
First Hospital of China Medical University

Recruiting

Reference Range for Tissue Motion Tracking of Mitral Annulus Displacement in Chinese Han Singleton Pregnancies

Pregnancy

China
Neurotronic, Inc.
Libra Medical

Recruiting

Ablation of Arteries for the Treatment of Type 2 Diabetes Mellitus and Its Comorbidities (NECTAR IV)

Hypertension | Diabetes Mellitus, Type 2

Georgia
Wex Pharmaceuticals Inc.

Recruiting

A Randomized, Double-Blind, Placebo Controlled, Multicenter, Efficacy and Safety Trial of Single Cycle Tetrodotoxin in the Treatment of Chemotherapy Induced Neuropathic Pain

Chemotherapy-induced Peripheral Neuropathy | Chemotherapy-induced Neuropathic Pain

United States
ReFlow Medical, Inc.

Recruiting

A Prospective Single-Arm Multicenter StuDy of the BarE TEmporary SPur StEnt System foR the tREatment of Vascular Lesions Located in the infrapoplitEal Arteries beLow the Knee (DEEPER REVEAL) (DEEPER REVEAL)

Peripheral Arterial Disease | Critical Limb Ischemia

United States
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Recruiting

Performances on Cognitive Functions and Brain Function and Follow-up After Different Treatments in Patients With Autonomous Cortisol Secretion: a Single-center, Prospective, Observational Study

Adrenal Incidentaloma | Autonomous Cortisol Secretion | Non-functioning Adrenal Adenomas

China
Beyond Air Inc.

Recruiting

A Study to Assess the Safety and Efficacy of Nitric Oxide Injection Into Unresectable Solid Primary or Metastatic Tumors

Cancer

Israel
Ankit Sarin
Yale University; University of California, San Francisco; University of Massachusetts... and other collaborators

Recruiting

Evaluation of SINGLE PORT (SP) Robotic Technology in Colorectal Surgery

Colorectal Disorders | Colo-rectal Cancer | Colostomy Stoma | Rectal Prolapse

United States
Cochlear
NAMSA

Recruiting

Investigation to Evaluate the Safety and Effectiveness of Cochlear Implantation in Children and Adults With Unilateral Hearing Loss/Single-sided Deafness (PAS-SSD)

Hearing Loss, Unilateral | Deafness, Unilateral

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not yet recruiting

Effect of Albumin-bound Paclitaxel Plus Carboplatin Compared With Paclitaxel Plus Carboplatin in Patients Receiving Neoadjuvant Chemotherapy for Advanced Ovarian, Fallopian Tube or Peritoneal Cancer: A Phase 2 Single Center Clinical Trial

Ovarian Cancer
National Taiwan University Hospital

Recruiting

A Single Center, Randomized, Open Label, Parallel Group, Phase 3 Study to Evaluate the Efficacy of Dapagliflozin in Subjects With Nonalcoholic Fatty Liver Disease

Fatty Liver

Taiwan
Johns Hopkins University

Recruiting

Effects of Psilocybin on Electrophysiology and the Dynamic Content of Thought

Healthy

United States
Hoffmann-La Roche

Recruiting

A Study to Evaluate the Efficacy and Safety of Giredestrant in Combination With Phesgo (Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf) Versus Phesgo in Participants With Locally Advanced or Metastatic Breast Cancer (heredERA Breast Cancer)

Locally Advanced or Metastatic Breast Cancer

France, Belgium, United States, Korea, Republic of, Taiwan, Brazil, China, Italy, Argentina, Jordan, Mexico, Germany, Portugal, Spain, Thailand, Turkey, United Kingdom, Kenya, Hungary, Poland, Colombia, India, Oman, Uganda, United Arab... and more
Physicians Laser and Dermatology Institute

Recruiting

A Prospective, Single Center, Single-Arm Clinical Study of 20 Participants to Reduce the Appearance of the Peri-orbital Wrinkles. Participants Will Receive up to Four Treatments With Tixel Every 4 Weeks. Follow-up Will Occur 1 Month and 3 Months Following Last Treatment.

Wrinkle

United States
University Hospitals Cleveland Medical Center
Case Western Reserve University; LEO Foundation

Recruiting

Development of Predictive Psoriasis Response Endotypes Using Single Cell Transcriptomics

Psoriasis

United States
Centre of Postgraduate Medical Education
Pomeranian Medical University Szczecin; Nicolaus Copernicus University; Medical... and other collaborators

Recruiting

Cervical Occlusion Double-level Stitch Application (COSA)

Cervical Incompetence

Poland
Virogin Biotech Canada Ltd

Recruiting

Phase I Study VG2025 as a Single Agent and in Combination Therapy With Nivolumab in Subjects With Advanced Malignant Solid Tumors

Solid Tumor

United States
Shanghai Zhongshan Hospital

Recruiting

A Single Center Study of Donafenib Combined With PD-1 + TACE in the First-line Treatment of aHCC

Donafenib

China
Sun Yat-sen University

Recruiting

Retro-Auricular Single-Site Endoscopic to Papillary Thyroid Carcinoma

Papillary Thyroid Carcinoma

China
Loxo Oncology, Inc.
Eli Lilly and Company

Recruiting

A Study of Pirtobrutinib (LOXO-305) Versus Ibrutinib in Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL) (BRUIN-CLL-314)

Chronic Lymphocytic Leukemia | Leukemia, B-cell | Small Lymphocytic Lymphoma | Leukemia, Lymphocytic

United States, Spain, Canada, Korea, Republic of, Taiwan, Australia, Japan, New Zealand, Italy, Czechia, China, Hungary, Israel, Belgium, France, Poland, Germany, Argentina, United Kingdom, Brazil, Turkey, Chile, Austria
HiFiBiO Therapeutics

Recruiting

A Study of HFB200301 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid Tumors

Melanoma | Sarcoma | Renal Cell Carcinoma | Cervical Cancer | Testicular Germ Cell Tumor | Gastric Cancer | Non Small Cell Lung Cancer | Mesothelioma | Head and Neck Squamous Cell Carcinoma

United States, Spain
Sanofi

Recruiting

Single Ascending Dose Study of SAR439459 in Adults With Osteogenesis Imperfecta (OI)

Osteogenesis Imperfecta

United States, Australia, Canada, France
Antonios Likourezos

Recruiting

Single Dose Amikacin for Uncomplicated Cystitis in the ED: A Feasibility Study

Urinary Tract Infections

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Trevarx Biomedical, Inc

Recruiting

A Radiotracer ([18F]FluorThanatrace) by PET/CT for the Imaging of Breast Cancer

Breast Carcinoma

United States
Maisonneuve-Rosemont Hospital
McGill University Health Centre/Research Institute of the McGill University...

Recruiting

Single Pre-Operative Radiation Therapy - With Delayed or No Surgery (SPORT-DNS) (SPORT-DNS)

Breast Cancer

Canada
Relay Therapeutics, Inc.

Recruiting

First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Advanced Solid Tumor Patients and in Combination With Fulvestrant in Patients With Advanced Breast Cancer

Breast Cancer | Advanced Breast Cancer | Metastatic Breast Cancer | Solid Tumor, Adult | HER2-negative Breast Cancer | Unresectable Solid Tumor | PIK3CA Mutation

United States, Spain, France, Italy
Salzburger Landeskliniken

Recruiting

Safety and Efficiency of Electrocautery-enhanced Lumen-apposing Stents - a Single Center Experience

Complication

Austria
Bispebjerg Hospital
The Novo Nordisk Foundation Center for Basic Metabolic Research

Recruiting

Mapping the Human Appendix Using Single Cell Sequencing (APPATA)

Diabetes | Inflammatory Bowel Diseases | Appendicitis

Denmark
Center for Eye Research Australia
AlphaRET Pty Ltd.

Recruiting

Subthreshold Laser Treatment in Intermediate Age-related Macular Degeneration With Nascent Geographic Atrophy Study (LIANA)

Age-Related Macular Degeneration

Australia
IntraGel Therapeutics

Not yet recruiting

A Single Arm, Prospective, Open Label, Multi Center, Phase Ib Study to Evaluate the Safety, Tolerability and Initial Efficacy of a Single Intra-tumoral Injection of IntraGel's Polymer-based Cisplatin-loaded Gel (TumoCure) in Subjects With Progressive or Radio-resistant Primary Head and Neck Tumor

Head and Neck Cancer

Israel
Wuhan Union Hospital, China

Recruiting

A Single-Arm Phase II Exploratory Clinical Study of Pemigatinib in the Treatment of Advanced Gastric and Colorectal Cancer Patients With FGFR Alterations Who Have Failed Standard Therapy

Gastric and Colorectal Cancer

China
Shanghai Zhongshan Hospital

Recruiting

A Single Center Real-world Study of Donafenib in the Treatment of Hepatocellular Carcinoma in Routine Clinical Practice

Hepatocellular Carcinoma | Donafenib

China

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