Search clinical trials for: Tissue Plasminogen Activator

Total 62003 results

Cerevast Therapeutics, Inc.

Terminated

Phase 3, Randomized, Placebo-Controlled, Double-Blinded Trial of the Combined Lysis of Thrombus With Ultrasound and Systemic Tissue Plasminogen Activator (tPA) for Emergent Revascularization in Acute Ischemic Stroke (CLOTBUST-ER)

Acute Ischemic Stroke

United States
Johns Hopkins University

Completed

Intraventricular Rt-PA in Patients With Intraventricular Hemorrhage

Cerebral Hemorrhage

United States
University of Virginia
National Institute of Neurological Disorders and Stroke (NINDS)

Terminated

Study of Tenecteplase (TNK) in Acute Ischemic Stroke (TNK-S2B)

Stroke

United States
Kaiser Permanente
Genentech, Inc.

Completed

Alteplase for Percutaneous Treatment of Loculated Abdominopelvic Abscesses

Abdominal Abscess | Pelvic Abscess

United States
Children's Mercy Hospital Kansas City

Completed

Treatment of Abdominal Abscesses With or Without Fibrinolysis

Abdominal Abscess | Tissue Plasminogen Activator

United States
The Second Artillery General Hospital
Hunan Rui Kang Tong technology development co., LTD

Unknown

Mechanical Opening Device Implantation Following Intravenous r-tPA for Recanalization in Acute Ischemic Stroke

Ischemic Cerebrovascular Accident
Rigshospitalet, Denmark

Completed

Evaluation of a New Radiotracer (64Cu-DOTA-AE105) for Diagnosing Aggressive Cancer With Positron Emission Tomography

Breast Cancer | Prostate Cancer | Urinary Bladder Cancer

Denmark
Wuhan General Hospital of Guangzhou Military Command

Unknown

Outcome of Intravenous Thrombolysis for Stroke Patients in the 3-4.5 Hour Time Window

Stroke
Rabin Medical Center

Unknown

Perfusion Computer Tomography: Imaging and Clinical Validation Following Reperfusion Therapy in Acute Ischaemic Stroke

Ischemic Stroke

Israel
The University of Texas Health Science Center,...
Genentech, Inc.

Completed

Safety of Intravenous Thrombolysis for Wake-up Stroke (Wake-Up Stroke)

Ischemic Stroke

United States
Richard Chang, M.D.
National Institutes of Health Clinical Center (CC)

Completed

Low-Dose Alteplase to Treat Blood Clots in Deep Leg Veins

Acute Deep Venous Thrombosis of the Lower Extremity

United States
Boehringer Ingelheim

Terminated

A Study of Pre-hospital Treatment of Acute Myocardial Infarction Based on Diagnosis by Interpretation of Remotely Acquired ECG and Thrombolysis With Accelerated Alteplase ( Actilyse®) (PHARAOH)

Myocardial Infarction
Boehringer Ingelheim

Completed

An International Observational Study of the Safety and Efficacy of Thrombolysis in Stroke

Stroke
Boehringer Ingelheim

Terminated

Protocol for Post Marketing Surveillance of Actilyse Vial

Stroke
Boehringer Ingelheim

Completed

Safe Implementation of Thrombolysis in Stroke - Monitoring Study

Stroke
Centocor, Inc.
Eli Lilly and Company

Completed

A Study of Abciximab and Reteplase When Administered Prior to Catherization After a Myocardial Infarction (Finesse)

Myocardial Infarction

United States, France, United Kingdom, Belgium, Germany, Spain, Poland, Bulgaria, Romania, Israel, Sweden, Canada, Czech Republic, Argentina, Austria, Denmark, Netherlands, South Africa, Switzerland
Boehringer Ingelheim

Completed

Full Dose Tenecteplase (TNK-tPA) Together With Heparin Sodium, Full Dose Tenecteplase With Enoxaparin, Half Dose Tenecteplase Together With Abciximab and Heparin Sodium in Patients With Acute Myocardial Infarction (AMI) (ASSENT 3)

Myocardial Infarction
Boehringer Ingelheim

Completed

A Study to Investigate the Procoagulant Effect of Tenecteplase (TNK-tPA), Alteplase (Rt-PA) and Streptokinase (SK) Administered to Patients With Acute Myocardial Infarction (AMI)

Myocardial Infarction
Niguarda Hospital

Completed

Intra-arterial Versus Systemic Thrombolysis for Acute Ischemic Stroke (SYNTHESIS EXP)

Stroke | Cerebrovascular Accident

Italy
SOS Attaque Cérébrale

Terminated

Thrombectomy Under Reopro Versus Alteplase to Treat Stoke (TURANDOT)

Infarction, Middle Cerebral Artery

France
Kyorin University

Completed

Submacular Hemorrhage Associated With Retinal Arterial Macro Aneurysm

Submacular Hemorrhage | Ruptured Retinal Arterial Macro Aneurysms

Japan
University of Cincinnati
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Study of the Combination Therapy of Rt-PA and Eptifibatide to Treat Acute Ischemic Stroke (CLEAR-ER)

Stroke | Ischemic Stroke | Brain Infarction

United States
Genentech, Inc.

Completed

Cathflo Activase Pediatric Study

Dysfunctional Central Venous Access Devices (CVADS)
Georgetown University
Johns Hopkins University; University of Alabama at Birmingham; University of... and other collaborators

Completed

Acute Stroke Program of Interventions Addressing Racial and Ethnic Disparities (ASPIRE)

Stroke

United States
University Health Network, Toronto

Terminated

Safety and Effectiveness of tPA in Intra-abdominal Abscesses

Abscess

Canada
Ahi Evren Chest and Cardiovascular Surgery Education...

Unknown

Low Dose Prolonged Infusion of Tissue Type Plasminogen Activator Therapy in Massive Pulmonary Embolism

Pulmonary Embolism

Turkey
Joseph Broderick
Medical University of South Carolina; National Institute of Neurological Disorders... and other collaborators

Terminated

Interventional Management of Stroke (IMS) III Trial (IMSIII)

Stroke

Canada, United States, Switzerland, Germany, Spain, Netherlands, Australia, France
Ataturk University

Unknown

Comparison of Low-Molecular-Weight Heparin (LMWH) and Unfractionated Heparin (UFH) in Combination With Thrombolytic Treatment of Acute Massive Pulmonary Thromboembolism

This Study Will Provide Data Comparing Safety of LMWH Versus UFH in the Treatment of Acute PE Cases Who Require Thrombolytic Treatment.

Turkey
University of California, San Diego
National Institute of Neurological Disorders and Stroke (NINDS); Scripps Health

Withdrawn

Study for the Use of Alteplase in Patients Who Awaken With Stroke (AWOKE)

Ischemic Stroke

United States
Melbourne Health
Boehringer Ingelheim

Completed

Echoplanar Imaging Thrombolysis Evaluation Trial (EPITHET)

Stroke

Australia, New Zealand, Belgium, United Kingdom
Mayo Clinic

Completed

Early Mobilization of Ischemic Stroke Patients Within 24-hours After Intravenous-Tissue Plasminogen Activator (IV-tPA) (EMISTPA)

Ischemic Stroke

United States
University of Michigan
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Increasing Stroke Treatment Through Interventional Change Tactics Study (INSTINCT)

Stroke

United States
Vanderbilt University
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health... and other collaborators

Completed

Renin-Angiotensin Aldosterone System and Fibrinolysis Interaction in Humans-Specific Aim 3

Obesity

United States
National Institute of Neurological Disorders and...

Completed

Combination Anti-Platelet and Anti-Coagulation Treatment After Lysis of Ischemic Stroke Trial (CATALIST) (CATALIST)

Ischemic Stroke

United States
Niguarda Hospital

Completed

Local Versus Systemic Thrombolysis for Acute Ischemic Stroke (SYNTHESIS)

Stroke | Cerebrovascular Accident

Italy
Centre Hospitalier du Centre du Valais

Unknown

Prolonged Hemodialysis Catheter Survival With Copolymer Coating and Rt-PA (PROCOPrt-PA)

Thrombosis | Malfunction; Catheter | Mechanical Complication of Hemodialysis Catheter

Switzerland
University of Cincinnati
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Interventional Management of Stroke (IMS) II Study

Stroke

United States
Northwestern University
National Cancer Institute (NCI)

Completed

In Vivo Angiostatin Generation Using Tissue Plasminogen Activator and Captopril in Treating Patients With Progressive Metastatic Cancer

Unspecified Adult Solid Tumor, Protocol Specific

United States
Midwest Pulmonary and Critical Care
Genentech, Inc.

Completed

Efficacy and Safety of Activase (Ateplase) vs Placebo in Complicated Pleural Effusions (CPE)/Empyemas (CPE)

Pleural Effusion Associated With Pulmonary Infection | Bacterial Pleural Effusion Other Than Tuberculosis

United States
Jacobs Neurological Institute
Genentech, Inc.; University at Buffalo Neurosurgery

Unknown

Wake up Symptomatic Stroke - Benefit of Intravenous Clot Busters or Endovascular Intervention (WASSABI)

Stroke

United States
Mitsubishi Tanabe Pharma Corporation
Kyowa Hakko Kogyo Co., Ltd.

Completed

Japan Alteplase Clinical Trial (J-ACT): Efficacy and Safety Study of Tissue Plasminogen Activator (Alteplase) for Ischemic Stroke

Brain Ischemia | Cerebral Infarction

Japan
Beijing Chao Yang Hospital
Ministry of Science and Technology of the People´s Republic of China

Unknown

Low Dose Rt-PA for Acute Normotensive Pulmonary Embolism With RVD

Pulmonary Embolism | Pulmonary Thromboembolisms

China
Bastyr University
University of Washington

Completed

Feeding the Rainbow to Investigate Endothelial Dysfunction (FRIED)

Cardiovascular Disease | Dietary Modification

United States
David Hess, MD
National Institute of Neurological Disorders and Stroke (NINDS); Oregon Health... and other collaborators

Completed

Study of a Neuroprotective Drug to Limit the Extent of Damage From an Ischemic Stroke (MINOS)

Stroke, Acute

United States
University of North Carolina, Chapel Hill
Genentech, Inc.

Completed

IV vs. IA tPA (Activase) in Acute Ischemic Stroke With CTA Evidence of Major Vessel Occlusion

Ischemic Stroke

United States
Kartal Kosuyolu Yuksek Ihtisas Education and Research...

Completed

Comparison of Different TRansesophageal Echocardiography Guided thrOmbolytic Regimens for prosthetIc vAlve Thrombosis (TROIA)

Prosthetic Valve Thrombosis

Turkey
Hospital Universitari Vall d'Hebron Research Institute

Completed

Efficacy and Security of Intrapleurally Alteplase vs Urokinase for the Treatment of Complicated Parapneumonic Effusion and Empyema

Pleural Diseases | Pleural Effusion | Empyema, Pleural

Spain
Aarhus University Hospital
TRYG Foundation; Danish National Research Foundation; Aase and Ejnar Danielsens...

Completed

New Acute Treatment for Stroke - The Effect of Remote PERconditioning

Acute Stroke

Denmark
University of California, San Diego
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Intravenous Thrombolysis Plus Hypothermia for Acute Treatment of Ischemic Stroke

Stroke

United States
Thrombotech Ltd.

Unknown

Study to Assess the Safety and Efficacy of THR-18 When Administered to Patients Suffering Acute Ischemic Stroke and Treated With Tissue Plasminogen Activator (tPA)

Acute Ischemic Stroke

Israel

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