Search clinical trials for: dose reduction

Total 25158 results

Shenzhen Ausa Pharmed Co.,Ltd
Peking University First Hospital; China Medical University, China; Fudan University and other collaborators

Unknown

Efficacy of Amlodipine-folic Acid Tablets on Reduction of Blood Pressure and Plasma Homocysteine

Essential Hypertension

China
University Hospital, Limoges

Completed

Reduction in the Risk of Rejection by Mycophenolate Mofetil Dose Adjustment in Liver Transplant Patients With Side Effects Caused by the Calcineurine Inhibitors (MONOCEPT)

Liver Transplantation

France
Central South University

Unknown

Atorvastatin for Reduction of Myocardial Damage During Angiography and Its Mechanism Associated With IMR (ARMYDA-IMR)

Stable Angina | Unstable Angina | Acute Non-ST-segment Elevation Myocardial Infarction

China
Weill Medical College of Cornell University
Schering-Plough

Terminated

Treatment of Anemia and Neutropenia in HIV/HCV Coinfected Patients Treated With Pegylated Interferon and Ribavirin

HIV Infections | Anemia | Neutropenia | Hepatitis C Virus

United States
Capstone Therapeutics

Completed

A Study to Evaluate the Safety and Efficacy of Additional Doses of AZX100 Drug Product Following Excision of Keloid Scars

Scar Prevention | Scar Reduction

United States
University of Michigan Rogel Cancer Center
Aventis Pharmaceuticals; Rhone-Poulenc Rorer

Completed

Phase II Study of Tailored-Dose Docetaxel in Metastatic Breast Cancer

Metastatic Breast Cancer

United States
Rennes University Hospital
Ministry of Health, France

Terminated

Reduction of Tacrolimus Dose in Association With Mycophenolate Mofetil After Liver Transplantation (MMF-FK)

Evidence of Liver Transplantation

France
Hamilton Health Sciences Corporation

Unknown

Investigation of High Resolution Nuclear Breast Imaging Camera (MBI) in Patients Administered Tc-99m Sestamibi (ROSE) (ROSE)

Breast Lesions

Canada
University Hospital, Geneva

Unknown

Safety of Reduced Dose Zidovudine (AZT) Compared With Standard Dose AZT in Antiretroviral-naïve HIV-infected Patients (AZTlowdose)

HIV | Zidovudine Adverse Reaction

Cameroon
University Hospital, Rouen

Completed

Renal Function Evaluation After Reduction of Cyclosporine A Dose in Renal Transplant Patients (DICAM)

Kidney Transplantation | Primary Prevention | Kidney Failure
Universitaire Ziekenhuizen KU Leuven

Completed

Reasons for Mycophenolate Mofetil Dose Reduction and Impact on Graft Outcome in Renal Transplant Recipients

Acute Rejection of Renal Transplant | Renal Graft Loss

Belgium
Aeris Therapeutics

Completed

A Dose Ranging Study of the Aeris Polymeric Lung Volume Reduction (PLVR) System in Patients With Advanced Upper Lobe Predominant Emphysema

Advanced Emphysema

Germany
Helios Research Center

Completed

Ultrasound-guided Axillary Plexus Block - Dose Reduction of Prilocaine

Other Surgical Procedures
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Comparing Cyclosporine Dose Reduction vs. Cyclosporine Elimination in Kidney Transplant Recipients Taking Sirolimus

Graft vs Host Disease | Kidney Failure

Brazil, Mexico
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Cyclosporine Dose Reduction and Cyclosporine Elimination in Chinese Kidney Transplants

Kidney Transplant
Kindai University

Completed

Study of Sorafenib In Combination With Low-dose 5-fluorouracil/Cisplatin (FP) Intraarterial Infusion Chemotherapy (SILIUS)

Hepatocellular Carcinoma

Japan
Daiichi Sankyo, Inc.

Completed

18 Week Study Evaluating Safety and Efficacy of Olmesartan, Amlodipine, and Hydrochlorothiazide, in Type 2 Diabetics

Hypertension | Type 2 Diabetes

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Comparing Cyclosporin Dose Reduction With Cyclosporin Elimination in Kidney Transplant Recipients Taking Sirolimus

Kidney Disease
General Hospital of Chinese Armed Police Forces
Ningxia Medical University; 181 Central Hospital of the Chinese PLA

Unknown

Clinical Values of Dose Reduction Techniques in Computed Tomography (CT) Coronary Artery Imaging With 64-row Multi-Slice Helical CT

Coronary Artery Disease

China
innoVactiv Inc.

Completed

Safety and Efficacy of a Single Dose of a Polyphenol-enriched Brown Seaweed Powder in Human (ICAST)

Glycemic Index

Canada
Sunnybrook Health Sciences Centre
General Electric

Unknown

Evaluation of Exposure Reduction Using Region-of-Interest Fluoroscopy (X-ray Fovea Imaging) in Cardiac Interventions

Cardiovascular Diseases

Canada
Hannover Medical School
Hoffmann-La Roche

Completed

Exchange of Azathioprine by Mycophenolatmofetile and Cyclosporine A Dose Reduction After Heart Transplantation

Heart Transplantation

Germany
Hannover Medical School
Hoffmann-La Roche

Completed

Withdrawal of Steroids, Cyclosporine A Dose Reduction and Switch to Mycophenolatmofetile After Heart Transplantation

Heart Transplantation

Germany
Marigot Ltd.

Completed

Effects of Aquamin F on NSAID Dose Reduction in Osteoarthritis of the Knee

Osteoarthritis of the Knee

United States
Tata Memorial Hospital

Unknown

Study of 3-Dimensional Conformal Radiotherapy (3D-CRT) Versus Intensity Modulated Radiotherapy (IMRT) for Head and Neck Squamous Cell Carcinoma (HNSCC)

Squamous Cell Carcinoma of the Head and Neck

India
AstraZeneca

Completed

High Doses of Candesartan Cilexetil on the Reduction of Proteinuria

Proteinuria

Canada
University Health Network, Toronto

Completed

Dose Reduction in Thoracic CT

Lymphoma

Canada
Hospital Clinic of Barcelona

Completed

Study Comparing Reducing the Dose of Stavudine Versus Switching to Tenofovir in HIV-Infected Patients Receiving Antiretroviral Therapy

HIV Infections | Lipoatrophy
Gustave Roussy, Cancer Campus, Grand Paris

Unknown

Randomized Trial Of Platelet Transfusion Policies After Blood Stem Cells Transplantation In Young Children: Reduction Of Number Of Single Platelet Concentrate Donors Per Child

Children Treated With High-Dose Chemotherapy (HDC) Followed by Haematopoietic Stem Cell Transplantation (HSCT)

France
Peking University People's Hospital

Recruiting

Antibiotic Exposure During Pregnancy Affects Infant Gut Microbiota

Antibiotics Affecting Newborn Gut Microbiota

China
University of New Mexico

Not yet recruiting

Cognitive Strategies for Optimizing Brain Health And Managing Transgenerational Vascular Risk Factors Post-Stroke (CHAMPS-TR)

Stroke, Ischemic
Chiesi Farmaceutici S.p.A.

Not yet recruiting

Real-World Effectiveness of a Triple Combination BDP/FF/GB in a Single Pressurised Metered Dose Inhaler in COPD Patients (TRIPHY) (TRIPHY)

Chronic Obstructive Pulmonary Disease
Teva Branded Pharmaceutical Products R&D, Inc.

Not yet recruiting

An Open-label Dose Escalation/Expansion Trial to Evaluate the Safety and Anti-tumor Activity of TEV-56278 Alone or in Combination With Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors

Advanced Solid Tumors
Mondelēz International, Inc.
INQUIS Clinical Research

Not yet recruiting

Evaluating the Impact of Incremental Doses of a Sugar Replacer Blend on Gastrointestinal Tolerance in Chocolate

Gastrointestinal Tolerance | Healthy Population

Canada
University of Oxford

Recruiting

COV-CHIM02: SARS-CoV-2 Omicron BA.5 Subvariant Dose Finding Infection Study

SARS-CoV-2 Infection

United Kingdom
Sichuan University

Recruiting

Phase 1b/2 Study of LDRT in Combination With AK104 Plus Chemotherapy as First-line Treatment for ES-SCLC

SCLC, Extensive Stage

China
Enterprise Therapeutics Ltd

Recruiting

A Two-Part Study to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of Repeat Doses of Inhaled ETD001 in People With Cystic Fibrosis

Cystic Fibrosis

Germany, France, United Kingdom
Duke University
United States Department of Defense; Owlstone Ltd; Darwin Biosciences

Not yet recruiting

Single Dose Texas 2017 (H3N2) Challenge Study

Influenza Viral Infections
Vertanical GmbH

Not yet recruiting

Dose-Response Characterization of VER-01 in the Treatment of Patients With Chronic Non-specific Low Back Pain (RESPONSE)

Chronic Non-specific Low Back Pain
UNICANCER

Not yet recruiting

Dose Individualization of Chemotherapy in Patients With Gastrointestinal Cancers Lacking a Specific Liver Enzyme (FUDOSE)

Colorectal Cancer | Digestive Cancer
Bristol-Myers Squibb

Not yet recruiting

A Study to Evaluate the Safety, Tolerability, and Efficacy of Escalating Doses of BMS-986463 in Participants With Select Advanced Malignant Tumors.

Non-small Cell Lung Cancer (NSCLC) | High-grade Serous Ovarian Carcinoma (HGSOC) | Uterine Serous Carcinoma (USC)

United States, Canada
ARCAGY/ GINECO GROUP
Horizon 2020 - European Commission

Not yet recruiting

Utility of Adjusting Chemotherapy Dose & Dosing Schedule With the SALVage Weekly Dose-dense Regimen in Patients With Poor Prognostic OVARian Cancers Based on the Tumor Unfavorable Primary Chemosensitivity and Incomplete Debulking Surgery (SALVOVAR)

Ovarian Cancer

France
Bristol-Myers Squibb

Not yet recruiting

A Study to Evaluate the Safety, Tolerability, Drug Levels, and Drug Effects of Single Doses of BMS-986435 (MYK-224) in Healthy Chinese Participants

Healthy Volunteers

China
M.D. Anderson Cancer Center

Not yet recruiting

A Phase I Study Investigating the Combination of Cladribine, Low Dose Cytarabine and Sorafenib Alternating With Decitabine in Pediatric Relapsed and Refractory Acute Leukemias

Refractory Acute Leukemia | Relapsed Acute Leukemia

United States
CHU de Reims

Not yet recruiting

Comparison of Serum Myokine Dosages and Imaging Methods in the Evaluation of Sarcopenia in Patients With Hepatocellular Carcinoma (Myomachia)

Hepatocellular Carcinoma | Sarcopenia

France
Guard Therapeutics AB

Not yet recruiting

A Phase 2b Dose Finding Study of RMC-035 in Participants Undergoing Open-chest Cardiac Surgery (POINTER)

Kidney Injury Following Open-Chest Cardiac Surgery

Spain, Germany, Canada, Czechia
Massachusetts General Hospital
Dana-Farber Cancer Institute; University of Massachusetts, Boston

Not yet recruiting

Assessing E-Cigarettes for Tobacco Harm Reduction in the Context of Lung Cancer Screening

Electronic Cigarette Use | Nicotine Dependence | Smoking, Cigarette

United States
Sunway University
Universiti Putra Malaysia

Not yet recruiting

Reducing Salt and Sugar in Campus Foods: A Malaysian Study

Cardiovascular Diseases
Pfizer

Not yet recruiting

A Study to Assess Safety, Tolerability and Immunogenicity of RSVpreF From Multidose Vials in Healthy Female Adults. (Amélie)

Respiratory Syncytial Virus (RSV)

United States
Jemincare

Not yet recruiting

To Assess the Effects of Single Dose of JMKX001899 on QTc Interval in Healthy Subjects

Solid Tumor, Adult

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