Search clinical trials for: molecular profile

Total 99380 results

Pfizer

Completed

A Study Of Oral PF-02341066, A C-Met/Hepatocyte Growth Factor Tyrosine Kinase Inhibitor, In Patients With Advanced Cancer (PROFILE 1001)

Systemic Anaplastic Large-Cell Lymphoma | Non-Small Cell Lung Cancer ALK-positive | Non-Small Cell Lung Cancer c-Met Dependent | Non-Small Cell Lung Cancer ROS Marker Positive | Advanced Malignancies Except Leukemia

United States, Korea, Republic of, Australia, Japan
Rush University Medical Center
John H. Stroger Hospital

Completed

Attenuation of the Side Effect Profile of Regadenoson: Study With Aminophylline in Patients With Severe Kidney Disease Undergoing Myocardial Perfusion Imaging (ASSUAGE-CKD)

Patients With Severe Chronic Kidney Disease Being Evaluated With Nuclear Stress Testing of the Heart Using the Stress Agent Regadenoson

United States
Institut Curie

Completed

Biomarker Evaluation in Advanced Stage Cervical Cancer by an International Working Group. Tumor Stages (1B1 - 4) (BIO-RAIDs)

Cervical Cancer

France, Germany, Netherlands, Romania, Serbia
Memorial Sloan Kettering Cancer Center

Completed

Intensity-Modulated Radiation Therapy (IMRT) in the Treatment of Non-Anaplastic Non-Medullary Thyroid Cancer

Thyroid Cancer

United States
Centre Hospitalier Universitaire de Saint Etienne
Ministry of Health, France

Completed

Evaluation of the Efficacy of Serotoninergic Antidepressants in Bulimia Nervosa, According to Brain Serotonin Profile Determined by Positron Emission Tomography With [18F] MPPF.

Bulimia Nervosa

France
Factors Group of Nutritional Companies Inc.

Completed

Pharmacological Profile of Different Quercetin Formulations

Pharmacokinetics

Canada
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Tumor-Specific Clonotype, Metabolic Profile, and PET/CT in Predicting Chemotherapy Response in Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma

Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma

United States
NeuroSense Therapeutics Ltd.

Completed

A Pilot Study to Evaluate the PK Profile of PrimeC-ER Tablets in Healthy Adult Subjects

Pharmacokinetics

United States
Hellenic Cooperative Oncology Group
NIPD Genetics

Completed

Tumor Molecular Profiling in Patients With Prostate Cancer

Prostate Cancer | Metastatic Prostate Adenocarcinoma

Greece
Christoph P Hornik, MD MPH
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Pharmacokinetics and Safety Profile of Digoxin in Infants With Single Ventricle Congenital Heart Disease (DGX01)

Congenital Heart Disease

United States
Millennium Pharmaceuticals, Inc.

Completed

An Efficacy and Safety Study of Pevonedistat Plus Azacitidine Versus Single-Agent Azacitidine in Participants With Higher-Risk Myelodysplastic Syndromes (HR MDS), Chronic Myelomonocytic Leukemia (CMML) and Low-Blast Acute Myelogenous Leukemia (AML)

Myelodysplastic Syndromes | Leukemia, Myeloid, Acute | Leukemia, Myelomonocytic, Chronic

United States, Israel, Spain, France, Ireland, Canada, Germany, Czechia, Italy, Netherlands, Belgium, Bulgaria
Universiti Sains Malaysia

Completed

Impact of CYP2C19 Genotype-guided Clopidogrel and Ticagrelor Treatment on Platelet Function Test and Metabolomics Profile

Coronary Artery Disease (CAD)

Malaysia
NYU Langone Health

Completed

Identify Predictors That Distinguish Between Tofacitinib Responders and Non-responders Based on Genotype and Cellular and Molecular Profiles From Pinch Biopsies, Blood and Stool Samples

Ulcerative Colitis

United States
Hellenic Cooperative Oncology Group

Completed

Molecular Characterization of Gliomas Using a Broad Next Generation Sequencing (NGS)Panel

Malignant Glioma
Fondazione Policlinico Universitario Agostino Gemelli...

Completed

US NAB With ROSE Versus US FNAB With no ROSE

Lung Cancer

Italy
Ayub Teaching Hospital
Khyber Medical University Peshawar

Completed

Effect of Amlodipine on the Lipid Profile of Newly Diagnosed Hypertensive Patients

Hypertension | Hypercholesterolemia | Cholesterol Deposition
Samsung Medical Center

Completed

The Screening Protocol for The VIKTORY Trial

Stomach Neoplasms

Korea, Republic of
Fred Hutchinson Cancer Center
GlaxoSmithKline

Completed

Molecular Profile of Breast Cancer in Ugandan Patients With Stage IIB-III Breast Cancer

Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC v8 | Anatomic Stage IIIC Breast Cancer AJCC v8 | Prognostic Stage IIB Breast Cancer AJCC v8 | Prognostic Stage III Breast Cancer... and other conditions

Uganda
University Hospitals Cleveland Medical Center

Withdrawn

Endocrinology Profile in Patients Undergoing Clomiphene, Letrozole, and Combination Clomiphene and Letrozole Cycles

Infertility

United States
Centre Leon Berard
Roche Pharma AG

Completed

Evaluation of the Added Value of a Large Molecular Profiling Panel Versus a Limited Molecular Profiling Panel in Advanced Solid Tumors. (PROFILER 02)

Advanced Solid Tumor

France
AET Laboratories Private Limited

Completed

The Study Aims to Show Bioequivalence of the Test Product and the Reference Reference Product in a Crossover Design Study Healthy Volunteers. Additionally, the Safety Profile of Test Product Compared to Reference Product Will be Assessed.

To Determine Bioequivalence Under Fed Conditions
Universitätsklinikum Hamburg-Eppendorf
Deutsche Kinderkrebsstiftung

Active, not recruiting

International Society of Paediatric Oncology (SIOP) PNET 5 Medulloblastoma

Brain Tumors

Germany, Denmark, United Kingdom, Belgium, Poland, Ireland, Austria, Italy, Czechia, France, Netherlands, Norway, Portugal, Spain, Sweden, Switzerland
Overseas Pharmaceuticals, Ltd.

Completed

To Evaluate the Food Effect and the Absorption Profile of Ibuprofen Modified-Release Tablets 800 mg

Chronic Pain

China
AET Laboratories Private Limited

Completed

The Study Intends to Show Bioequivalence of the Test Product and the Reference Reference Product in a Crossover Design Study Healthy Volunteers. Additionally, the Safety Profile of Test Product Compared to Reference Product Will be Evaluated.

To Determine Bioequivalence Under Fed Conditions
AET Laboratories Private Limited

Completed

The Study Aims to Show Bioequivalence of the Test Product and the Reference Reference Product in a Crossover Design Study Healthy Volunteers. Additionally, the Safeyt Profile of Test Product Compared to Reference Product Will be Assessed.

Diabetes Mellitus
University Health Network, Toronto
Princess Margaret Hospital, Canada

Completed

Prospective Comprehensive Molecular Profiling In Neuroendocrine Tumors (NET-SEQ)

Neuroendocrine Tumors | Pancreatic Neuroendocrine Tumors

Canada
Elevar Therapeutics

Terminated

A Study to Evaluate Safety, Tolerability, and Efficacy Profile of Rivoceranib With Paclitaxel in Advanced Gastric or Gastroesophageal Junction Cancer

Gastric Cancer | Gastroesophageal Junction Adenocarcinoma

Korea, Republic of
Shanghai Zhongshan Hospital
Wuxi People's Hospital; Shanghai Minhang Central Hospital

Completed

Translational Study of Molecular Classification of Relapsed/Refractory Diffuse Large B-cell Lymphoma

Lymphoma, Large B-Cell, Diffuse | Gene Expression Profiling

China
Overseas Pharmaceuticals, Ltd.
Virginia Contract Research Organization Co., Ltd.

Terminated

To Evaluate the Food Effect and the Absorption Profile of Ibuprofen Controlled-Release Tablets 600 mg in Comparison to the Reference Standard Ibuprofen Tablets in Normal Healthy Volunteers

Pain Control

Taiwan
Hellenic Cooperative Oncology Group

Active, not recruiting

Melanoma: Genomic Profiles, Molecular Markers and Therapeutic Implications

Melanoma

Greece
Pfizer

Completed

A Phase 2b Study To Evaluate The Efficacy And Safety Profile Of PF-06651600 And PF-06700841 In Active Non-segmental Vitiligo Subjects

Active Non-segmental Vitiligo

Spain, United States, Korea, Republic of, Taiwan, Canada, Australia, Germany, Japan, Belgium, Italy
PepsiCo Global R&D

Completed

Pilot Study Characterizing the Pharmacokinetic Profile of a Novel Encapsulated Caffeine Beverage in the Fed and Fasted States

Pharmacokinetics

United States
D'Or Institute for Research and Education

Enrolling by invitation

Phenotypic Profile and Molecular Mechanism of Resistance in Carbapenemase-producing Enterobacterales and Pseudomonas Aeruginosa Isolates From Brazilian Hospitals: Implications for the Introduction of IMIPENEM-RELEBACTAM

Bacterial Infections | Antibiotic Resistant Infection

Brazil
Addpharma Inc.

Completed

A Study to Compare Pharmacokinetic Parameters and Safety Profiles Between AD-109 and AD-1091

Embolism and Thrombosis

Korea, Republic of
Inventage Lab., Inc.

Completed

A Clinical Trial to Assess Pharmacokinetic/Pharmacodynamic Profiles and Safety of IVL3001

Androgenetic Alopecia

Australia
Zambon SpA

Completed

Clinical Study to Evaluate Z7200 Pharmacokinetics Profile

Asthma

United Kingdom
Zambon SpA

Completed

A Clinical Study to Evaluate Z7200 (Budesonide/Formoterol) Pharmacokinetics Profile in Healthy Volunteers

Asthma

United Kingdom
M.D. Anderson Cancer Center
European Commission

Completed

Rational Therapeutics Based on Matched Tumor and Normal Tissue

Advanced Cancers

United States, Spain, France, Israel
University of California, San Diego

Terminated

An Open Label Navigational Investigation of Molecular Profile-Related Evidence Determining Individualized Cancer Therapy for Patients With Incurable Hematologic Malignancies (I-PREDICT Heme) (I-PREDICT Heme)

Hematologic Cancer

United States
University Hospital, Bordeaux

Completed

Safety Profile Evaluation of TICagrelor Alone Compared to a Combination of Lysine Acetylsalicylate-Clopidogrel in the Context of Transcatheter Aortic Valve Implantation (TAVI) (TICTAVI)

Aortic Valve Stenosis

France
Dexa Medica Group

Completed

DLBS1442 for The Treatment of Pain in Patients Suspected Endometriosis

Endometrioma | Visual Analogue Pain Scale: Moderate or Severe Pain

Indonesia
Skane University Hospital

Completed

Drug Eluting Balloon (DEB) vs Plain Old Balloon Angioplasty (POBA) in the Treatment of Failing Dialysis Access

Vascular Diseases | Kidney Diseases
Gruppo Italiano Malattie EMatologiche dell'Adulto

Active, not recruiting

Activity and Risk Profile of Ponatinib in Chronic Phase Patients With Chronic Myeloid Leukemia Resistant to Imatinib

Chronic Myeloid Leukemia | Adults | Chronic Phase

Italy
Eisai Inc.
Merck Sharp & Dohme LLC

Completed

A Trial of Lenvatinib (E7080) in Subjects With Iodine-131 Refractory Differentiated Thyroid Cancer to Evaluate Whether an Oral Starting Dose of 18 Milligram (mg) Daily Will Provide Comparable Efficacy to a 24 mg Starting Dose, But Have a Better Safety Profile

Thyroid Cancer

United States, Canada, Germany, Korea, Republic of, Spain, France, Australia, Belgium, Denmark, Israel, Italy, Poland, Romania, Russian Federation, Sweden, United Kingdom
Gilead Sciences

Completed

Safety Profile of Idelalisib in Patients With Refractory Follicular Lymphoma (ZEUS)

Follicular Non-Hodgkin's Lymphoma Refractory

Spain, France, Ireland, Italy, Greece, Germany, United Kingdom, Sweden, Belgium, Portugal
TFF Pharmaceuticals, Inc.

Completed

Pharmacokinetic Profile of Voriconazole Inhalation Powder in Adult Subjects With Asthma

Asthma

Australia
Yarmouk University

Completed

Antibiotic Profile of Pathogenic Bacteria Isolated in Public Hospitals in Northern Jordan

Bacterial Infections | Surgical Site Infection | Antibiotic Resistant Infection

Jordan
Shiraz University of Medical Sciences

Completed

Effect of Red Yeast Rice Beside Statin on Lipid Profile

Hyperlipidemias

Iran, Islamic Republic of
Fondazione IRCCS Istituto Nazionale dei Tumori,...

Completed

Molecular Profile of Metastatic Sporadic Medullary Thyroid Cancer Patients and Correlation With Vandetanib

Metastatic Sporadic Medullary Thyroid Cancer

Italy
Nanjing First Hospital, Nanjing Medical University

Completed

Comparison of the FGM Profiles in Patients of Type 2 Diabetes Treated With Sitagliptin and Acarbose

Type 2 Diabetes

China

3

Subscribe