Search clinical trials for: respiratory exacerbation

Total 63855 results

Laval University

Recruiting

FreeDom: Innovative Strategy for the Management of COPD Exacerbations

Oxygen Deficiency | COPD Exacerbation

Canada
Ain Shams University
Trudell Medical International

Recruiting

Oscillating Positive Expiratory Pressure Devices and Acute Exacerbation of Chronic Obstructive Pulmonary Disease (SIMPLE)

Pulmonary Disease, Chronic Obstructive

Egypt
University of Alabama at Birmingham
National Heart, Lung, and Blood Institute (NHLBI); University of Pittsburgh; Brigham... and other collaborators

Recruiting

Autoantibody Reduction for Acute Exacerbations of Idiopathic Pulmonary Fibrosis (STRIVE-IPF)

Idiopathic Pulmonary Fibrosis, Acute Fatal Form

United States
Vanderbilt University Medical Center

Not yet recruiting

Pragmatic RCT of High-dose Oral Montelukast for Moderate and Severe Pediatric Acute Asthma Exacerbations

Asthma in Children | Asthma Attack | Asthma Acute | Acute Asthma Exacerbation | Asthma; Status

United States
Guangzhou Institute of Respiratory Disease
Guangdong Provincial Hospital of Traditional Chinese Medicine

Not yet recruiting

Lung Dispersing, Turbid Descending and Gut Clearing Decoction for Bronchiectasis (LUNG-CLEAR)

Quality of Life | Bronchiectasis Adult | Traditional Chinese Medicine | Exacerbation
Unity Health Toronto

Recruiting

High Flow Nasal Cannula Versus Non-Invasive Ventilation in Exacerbations of Chronic Obstructive Pulmonary Disease (HiFOLD)

Acute Hypercapnic Respiratory Failure | Acute Respiratory Distress | Exacerbation Copd

Canada
Imperial College London

Recruiting

The London COPD Exacerbation Cohort (EXCEL_Cohort)

Pulmonary Disease, Chronic Obstructive

United Kingdom
University Hospital, Lille

Recruiting

Study of the Involvement of IL-17 / IL-22 Pathway in Bacterial Exacerbations of COPD (COPD1722)

Pulmonary Disease, Chronic Obstructive | Bacterial Infections

France
Hamad Medical Corporation

Recruiting

Two Doses of the Intravenous Magnesium Sulfate Versus the Standard Single Dose ,With/ Without the Nebulized Budesonide For the Management of the Severe Asthma Exacerbation in the Emergency Room; A Randomized Controlled Trial.

Bronchial Asthma

Qatar
Prof. Dr. Jörg Leuppi
Kantonsspital Baselland Bruderholz; Institut für Hausarztmedizin Basel

Recruiting

Reduction of Corticosteroid Use in Outpatient Treatment of Exacerbated COPD (RECUT)

Pulmonary Disease, Chronic Obstructive | Disease Exacerbation | Adverse Effect of Glucocorticoids and Synthetic Analogues

Switzerland
Guangzhou Institute of Respiratory Disease

Recruiting

Sputum Microbiota and the Association With Clinical Parameters in Steady-state, Acute Exacerbation and Convalescence of Bronchiectasis (BISER-2)

Bronchiectasis

China
Rabin Medical Center

Recruiting

Dexamethasone Versus Prednisone in Heart Failure Patients, Hospitalized With Exacerbation of Chronic Obstructive Pulmonary Disease.

Heart Failure | Chronic Obstructive Pulmonary Disease

Israel
Prof. Dr. Jörg Leuppi

Recruiting

Swiss Chronic Obstructive Pulmonary Disease (COPD) Management Cohort

Chronic Obstructive Pulmonary Disease | COPD Exacerbation

Switzerland
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Longitudinal Observational Study of Severe Asthma

Asthma

United States
Guangzhou Institute of Respiratory Disease

Recruiting

Bacteriology and Inflammation in Bronchiectasis (BISER)

Bronchiectasis

China
Gelb, Arthur F., M.D.

Recruiting

Mechanism(s) of Airflow Limitation During Exacerbation of Asthma

Asthma

United States
University of Massachusetts, Worcester
UMass Memorial Health

Active, not recruiting

Healthy at Home Pilot

COPD | COPD Exacerbation | Emphysema or COPD

United States
Columbia University
Alpha-1 Foundation

Terminated

COPD Exacerbation Blood and Urine Biomarkers Study

Chronic Obstructive Pulmonary Disease | Acute Exacerbation Copd | Alpha-1 Anti-trypsin Deficiency

United States
McGill University Health Centre/Research Institute...

Completed

Wearable Devices in the Recovery Phase of Acute Exacerbations of COPD (AECOPDs)

Chronic Obstructive Pulmonary Disease | Chronic Obstructive Pulmonary Disease Exacerbation

Canada
Professor Francine Ducharme
Canadian Institutes of Health Research (CIHR); EURO-PHARM International Canada...

Active, not recruiting

Vitamin D In the Prevention of Viral-induced Asthma in Preschoolers (DIVA)

Asthma

Canada
Institut d'Investigacions Biomèdiques August Pi...
Hospital Clinic of Barcelona

Enrolling by invitation

K-HEALTH in AIR - Barcelona Pilot - Cohort

COPD | Severe Asthma

Spain
Tel-Aviv Sourasky Medical Center
AstraZeneca

Enrolling by invitation

The Effect of Asthma Flare-up Clinic After Exacerbation

Asthma | Asthma Attack

Israel
University Hospital, Grenoble
AGIR à Dom

Completed

Early Supported Discharge and Enhanced Homecare After Emergency Department Admission for Acute Exacerbation of COPD (EXADOM)

COPD

France
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Examining Changes in Nasal IL-1 During Acute Asthma Exacerbation in Adolescents (Attack Asthma)

Asthma

United States
University of Alberta

Active, not recruiting

Vascular Implications of a Naturally Occurring Asthma Exacerbation

Inflammation | Asthma | Cardiovascular Risk Factor

Canada
Vertex Pharmaceuticals Incorporated

Completed

A Study Evaluating the Long-term Safety and Efficacy of Elexacaftor/Tezacaftor/Ivacaftor in Cystic Fibrosis (CF) Particpants 6 Years and Older and F/MF Genotypes

Cystic Fibrosis

Canada, France, United Kingdom, Israel, Australia, Spain, Germany, Netherlands, Denmark, Switzerland
AstraZeneca

Active, not recruiting

Efficacy and Safety of Benralizumab in Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) With a History of Frequent Exacerbations (RESOLUTE)

Chronic Obstructive Pulmonary Disease

United States, Austria, Canada, Denmark, Germany, Italy, Spain, United Kingdom, Belgium, Vietnam, Brazil, Hungary, Philippines, China, Korea, Republic of, Argentina, Australia, Poland, Turkey, Japan, Greece, Netherlands, Czechia, Mexico, Bulgar... and more
Vertex Pharmaceuticals Incorporated

Completed

A Study Evaluating the Long-term Safety and Efficacy of VX-445 Combination Therapy

Cystic Fibrosis

United States, Belgium, Netherlands, United Kingdom, Canada, Australia, France, Germany, Italy, Czechia, Austria, Sweden, Greece
GlaxoSmithKline
Iqvia Pty Ltd

Completed

Placebo-controlled Efficacy and Safety Study of GSK3511294 (Depemokimab) in Participants With Severe Asthma With an Eosinophilic Phenotype (SWIFT-1)

Asthma

United States, France, Germany, Poland, Spain, Italy, United Kingdom, China, Canada, Czechia, Russian Federation, Ireland
Assistance Publique - Hôpitaux de Paris
Xenios AG

Completed

Effects of Blood Pulsatility on Von Willebrand Factor During ECCO2R (FLOW-ECCO2R)

Acute Respiratory Distress Syndrome | Pulmonary Disease | Extracorporeal CO2 Removal | Chronic Obstructive Pulmonary Disease Exacerbation

France
Schön Klinik Berchtesgadener Land
GlaxoSmithKline GmbH & Co. KG (Munich, Germany); Coordinating Center for Clinical... and other collaborators

Active, not recruiting

Predictors of Acute Exacerbation in Patients With COPD - an Observational Study (PACE)

Chronic Obstructive Pulmonary Disease | COPD | COPD Exacerbation | COPD Exacerbation Acute

Germany
Areteia Therapeutics

Enrolling by invitation

Phase III Long-Term Extension Study With Dexpramipexole (EXHALE-5)

Eosinophilic Asthma

United States
Vertex Pharmaceuticals Incorporated

Active, not recruiting

Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA in Cystic Fibrosis (CF) Participants 2 Years and Older

Cystic Fibrosis

United States, United Kingdom, Canada, Australia, Germany
NHS Greater Glasgow and Clyde
AstraZeneca; Queen's University, Belfast; University of Plymouth; University of... and other collaborators

Completed

Benralizumab Exacerbation Study (BenRex)

Asthma

United Kingdom
Parc de Salut Mar

Active, not recruiting

Asthma Research in Children and Adolescents (ARCA)

Asthma in Children | Persistent Asthma | Asthma Exacerbation

Spain
Respiratory Effectiveness Group
Boehringer Ingelheim

Completed

Assessing the Utility of Peak Inspiratory Flow as a Predictor for COPD Exacerbations

Chronic Obstructive Pulmonary Disease

Korea, Republic of, Singapore, Malta, Italy, Slovenia, Spain
The Hospital for Sick Children
Canadian Cystic Fibrosis Foundation

Completed

Prednisone in Cystic Fibrosis Pulmonary Exacerbations (PIPE)

Cystic Fibrosis Pulmonary Exacerbation

Canada
Boehringer Ingelheim

Completed

Exacerbation Risk in Asthma

Asthma

United States
NanoVation

Completed

A Feasibility Study of Wearable Device in Assessing Respiratory Condition Change of Patients With Exacerbation of COPD

COPD Exacerbation

Israel, Germany
New York Presbyterian Brooklyn Methodist Hospital

Completed

Vibratory PEP Device and Hospital Length of Stay for Acute Exacerbation of COPD

Chronic Obstructive Pulmonary Disease

United States
Karl Landsteiner Institute for Lung Research and...
Klinik Ottakring; University of Vienna; Klinik Floridsdorf; Therme Wien Med (Ambulant...

Completed

Mindfulness-based Interventions in COPD Patients (SPIROMIND)

Chronic Obstructive Pulmonary Disease Exacerbation

Austria
ModernaTX, Inc.

Completed

Post-Marketing Safety Study in Japan in Participants With High Risk of Severe Exacerbation of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) mRNA-1273 COVID-19 Vaccine

SARS-CoV-2

Japan
Zhujiang Hospital

Completed

The Effect of EDP on Diaphragmatic Function and Neural Respiratory Drive in Patient With AECOPD

Acute Exacerbation of Chronic Obstructive Pulmonary Disease

China
University of Washington, the Collaborative Health...
Cystic Fibrosis Foundation

Completed

Streamlined Treatment of Pulmonary Exacerbations in Pediatrics (STOP-PEDS)

Cystic Fibrosis

United States
University of Wisconsin, Madison
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Respiratory Exacerbation Plans for Action and Care Transitions for Children With Severe CP (RE-PACT)

Cerebral Palsy

United States
ResApp Health Limited

Completed

A Study Evaluating the Use of ResAppDx v2.0 as an Aid to Diagnose Respiratory Disease in Adolescent and Adult Patients in an Emergency Department

Pneumonia | Asthma Exacerbation | COPD Exacerbation | Lower Respiratory Disease

United Kingdom
Ludocare SAS
Clinact

Active, not recruiting

Evaluation of Efficacy and Tolerance of JOE on 4 to 11 Years Old Asthmatic Patients of GINA 2,3,4 and 5 Grades (JoeCare)

Asthma in Children

France
EpiEndo Pharmaceuticals
CTC Clinical Trial Consultants AB

Completed

Clinical Trial to Assess Effect of Verapamil on Systemic Exposure of EP395 and Effect of EP395 on Systemic Exposure of Midazolam and Digoxin

COPD | Chronic Obstructive Pulmonary Disease Exacerbation

Sweden
GlaxoSmithKline

Completed

Etiology of Acute Exacerbations of Chronic Obstructive Pulmonary Disease (AECOPD) in Japan

Pulmonary Disease, Chronic Obstructive

Japan
AstraZeneca
Amgen

Completed

Tezepelumab COPD Exacerbation Study (COURSE)

Chronic Obstructive Pulmonary Disease (COPD)

United States, Canada, Denmark, France, United Kingdom, Korea, Republic of, Germany, Israel, Spain, Netherlands

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