Search clinical trials for: severe eosinophilic asthma, late-onset, fixed obstruction

Total 12679 results

Örebro County Council

Completed

Severe Aortic Valve Stenosis and Concomitant Coronary Artery Disease in Patients Undergoing TAVI

Coronary Artery Disease | Aortic Valve Stenosis

Sweden
AstraZeneca

Completed

Study to Characterise Patients Receiving Benralizumab in the Framework of an Individualized Access Program in Spain (ORBE)

Severe Eosinophilic Asthma

Spain
NeuroRx, Inc.
Massachusetts General Hospital; Target Health Inc.

Completed

Sequential Therapy for the Treatment of Severe Bipolar Depression. (STABIL-B)

Suicidal Ideation | Suicide, Attempted | Bipolar Depression | Suicidal Ideas

United States
Edwards Lifesciences

Completed

PARTNER II Trial: Placement of AoRTic TraNscathetER Valves II - High Risk and Nested Registry 7 (PII S3HR/NR7)

Symptomatic Severe Aortic Stenosis

United States, Canada
HLT Inc.

Completed

HLT transfemOral Replacement of aortIc Valve Via transcatherteriZatiON (HORIZON)

Aortic Valve Stenosis | Severe Aortic Stenosis

Germany
Menarini Group

Completed

Tramadol Hydrochloride and Dexketoprofen Trometamol for the Oral Treatment of Moderate to Severe Acute Pain Following Removal of Impacted Lower Third Molar (DAVID)

Acute Pain

Italy, Hungary, Spain, Poland, United Kingdom
RedHill Biopharma Limited

Completed

Open Label Efficacy and Safety of Anti-MAP (Mycobacterium Avium Ssp. Paratuberculosis) Therapy in Adult Crohn's Disease (MAPUS2)

Crohn Disease

United States, Canada, Czechia, Israel, New Zealand, Poland, Serbia
The Cleveland Clinic

Completed

Conduction Abnormalities With Severe Aortic Stenosis Before and After Transcatheter Aortic Valve Replacement

Bradycardia

United States
Johns Hopkins University

Completed

Benralizumab Effect on Severe Chronic Rhinosinusitis With Eosinophilic Polyposis

Chronic Rhinosinusitis (Diagnosis) | Nasal Polyps | Eosinophilia

United States
AstraZeneca

Completed

Prevalence of the Eosinophilic Phenotype Among Severe Asthma Patients (PREPARE)

Severe Asthma

Mexico, Argentina, Chile, Saudi Arabia, Colombia, Costa Rica
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Unknown

Safety, Tolerability and Pharmacokinetic of Recombinant Anti-IL-5 Humanized Monoclonal Antibody Injection

add-on Maintenance Treatment of Patients With Severe Eosinophilic Asthma

China
Queen Mary University of London

Unknown

Identification of Autoantigens in EGPA and Severe Eosinophilic Asthma (IDEA)

Eosinophilic Esophagitis | Churg-Strauss Syndrome | Eosinophilic Asthma | Eosinophilic Pneumonia

United Kingdom
University Medical Centre Ljubljana

Completed

Improved HRV, Inflammation Markers and Endothelial Function After TAVI (bTAVI)

TAVI | Severe Aortic Stenosis

Slovenia
Università degli Studi di Ferrara

Completed

Effects of Anti-IL5 Biological Treatments on Blood IgE Levels in Severe Asthmatic Patients (BIONIGE)

Asthma | Asthma; Eosinophilic

Italy
University of Newcastle, Australia
GlaxoSmithKline

Unknown

Comparing Treatment Efficacy With Mepolizumab and Omalizumab in Severe Asthma - "Choosebetweenamab".

Asthma | Eosinophilic Asthma

Australia
University Hospital, Clermont-Ferrand
Merck Sharp & Dohme LLC

Completed

Study to Investigate the Efficacy of Elbasvir/Grazoprevir Fixed-Dose Combination for 8 Weeks in Treatment-Naïve, HCV GT1b-Infected Patients, With Non-severe Fibrosis (STREAGER)

Chronic HCV Infection

France
Clinica San Camilo, Argentina

Unknown

Nebulized Heparin in Severe Acute Respiratory Syndrome COVID-19 (NEBUHEPA)

Pneumonia | Covid19

Argentina
Edwards Lifesciences

Completed

SOURCE XT REGISTRY

Severe Aortic Stenosis

Spain, Italy, Canada, Belgium, Greece, Germany, Austria, United Kingdom, Finland, Denmark, France, Switzerland, Israel, Poland, South Africa, Czechia, Netherlands, Norway
Assiut University
Manchester University NHS Foundation Trust

Unknown

Early Outcomes of Concomitant Transcatheter Aortic Valve Implantation and Off-pump Coronary Artery Bypass Grafting in Management of Severe Symptomatic Aortic Stenosis and Coronary Artery Disease

Coronary Artery Disease | Aortic Valve Disease

Egypt
AstraZeneca
Medical Writer: Dr. Rodrigo Athanazio; CRO: CTI-Eurotrials

Completed

BRazilian Asthmatics Patients EOSinophilic Profile (BRAEOS) (BRAEOS)

Severe Asthma

Brazil
Case Comprehensive Cancer Center

Completed

Combination Chemotherapy Followed By Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer or Severe Aplastic Anemia

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Diseases

United States
Klinik für Kardiologie, Pneumologie und Angiologie

Completed

Virtual Reality Assisted Conscious Sedation During TAVI (TAVI_VR)

Pain | Anxiety | Severe Aortic Valve Stenosis

Germany
University of Pennsylvania

Completed

Targeting Pulsatile Load to Increase Exercise Capacity and Quality of Life After Aortic Valve Replacement for Severe Aortic Stenosis (PULSE AS) (PULSE-AS)

Aortic Valve Stenosis

United States
Irmandade Santa Casa de Misericórdia de Porto Alegre
Federal University of Health Science of Porto Alegre

Unknown

Cardiovascular Rehabilitation in Patients With Severe Aortic Stenosis Submitted to Valvar Correction (CARE-AS-MOTION)

Aortic Valve Stenosis

Brazil
University Hospital, Rouen

Completed

Evaluation of Length of Stay After TF-TAVI (FAST-TAVI)

Severe Symptomatic Aortic Stenosis

France
Symetis SA

Completed

ACURATE Neo™ Aortic Bioprosthesis for Implantation Using the ACURATE TA™ LP Transapical Delivery System in Patients With Severe Aortic Stenosis (TALP-FIM)

Aortic Stenosis

Germany
University Hospital, Montpellier

Completed

Long-term Clinical and Echographic Follow-up (More Than 4 Years) After TAVI.

Severe and Symptomatic Aortic Stenosis

France
University Hospital, Montpellier

Completed

Vascular Complications and Bleeding After Transfemoral TAVI

Severe and Symptomatic Aortic Stenosis | Undergoing TAVI

France
NHS Greater Glasgow and Clyde
Queen's University, Belfast

Completed

Inflammation Following Mepolizumab and Oral Corticosteroids in Asthma (MAPLE)

Asthma

United Kingdom
GlaxoSmithKline

Completed

Cessation Versus Continuation of Long-term Mepolizumab in Severe Eosinophilic Asthma Patients

Asthma

United States, Argentina, Australia, Canada, France, Germany, Japan, Korea, Republic of, Netherlands, Poland, Romania, Russian Federation, Spain, Ukraine
University of Sao Paulo General Hospital

Unknown

A Pragmatic Study to Investigate the Efficacy and Safety of Mepolizumab in Severe Uncontrolled Asthma in Brazil

Eosinophilic Asthma

Brazil
GlaxoSmithKline

Completed

A Phase 3a, Repeat Dose, Open-label, Long-term Safety Study of Mepolizumab in Asthmatic Subjects

Asthma

United States, Argentina, Australia, Canada, France, Germany, Japan, Netherlands, Poland, Russian Federation, Spain, Ukraine, Belgium, Chile, Korea, Republic of, Czechia, Italy, United Kingdom
AstraZeneca

Completed

A Study to Evaluate the Onset of Effect and Time Course of Change in Lung Function With Benralizumab in Severe, Uncontrolled Asthma Patients With Eosinophilic Inflammation (SOLANA)

Asthma

United States, Germany, Korea, Republic of, Philippines, Hungary, Chile
University Hospital, Saarland

Unknown

Infranodal Conduction Time During TAVR as Predictor of HAVB (HOM-TAVI)

Left Bundle-Branch Block | Severe Aortic Valve Stenosis | High-degree AV Block

Germany
Medtronic Cardiovascular

Completed

Clinical Evaluation of MDT-2111 in Subjects With Small Aortic Annuli and Symptomatic Severe Aortic Stenosis

Aortic Valve Stenosis

Japan
National Heart, Lung, and Blood Institute (NHLBI)
Medstar Washington Hospital Center

Withdrawn

Use of Cardiac-MRI to Predict Results for People With Severe Aortic Stenosis

Aortic Valve Stenosis
Attikon Hospital

Unknown

Mepolizumab: Real World Evidence Study for the Treatment of Severe Eosinophilic Asthma in Greece

Severe Eosinophilic Asthma
Chiesi Farmaceutici S.p.A.
Atopix Therapeutics, Ltd.

Completed

Effect of OC000459 on Eosinophilic Airway Inflammation in Severe Asthma

Severe Eosinophilic Asthma

United Kingdom
GlaxoSmithKline

Completed

Omalizumab to Mepolizumab Switch Study in Severe Eosinophilic Asthma Patients

Asthma

United States, Argentina, France, Germany, Spain, Canada, Sweden, Netherlands, Belgium
Segeberger Kliniken GmbH

Completed

A Comparison of Transcatheter Heart Valves in High Risk Patients With Severe Aortic Stenosis: The CHOICE Trial (CHOICE)

Aortic Stenosis

Germany
University Hospital, Montpellier

Completed

Post TAVI Coronary REVASCularisation Guided by Myocardial Perfusion Imaging: a Prospective Open Label Pilot Study: The REVASC-TAVI Study (REVASC-TAVI)

Stable Coronary Disease | Severe and Symptomatic Aortic Stenosis

France
AstraZeneca

Completed

Pharmacokinetics, Safety and Tolerability of Twice-Daily Aclidinium Bromide/Formoterol Fumarate Fixed Dose Combination in Chinese Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease

Pulmonary Disease, Chronic Obstructive

China
TC Erciyes University

Completed

Identifying Serum Cytokine Profiles of Distinct Inflammatory Phenotypes in Severe Asthma

Chronic Rhinosinusitis (Diagnosis) | Eosinophilic Asthma | Asthma, Allergic | Asthma Persistent

Turkey
AstraZeneca
Parexel International Ltd; Cognizant Technology Solution; Center for Information... and other collaborators

Completed

Efficacy and Safety of Glycopyrronium/Formoterol Fumarate Fixed-dose Combination Relative to Umeclidinium/Vilanterol Fixed-dose Combination Over 24 Weeks in Patients With Moderate to Very Severe Chronic Obstructive Pulmonary Disease (AERISTO)

Chronic Obstructive Pulmonary Disease COPD

United States, Canada, France, Russian Federation, Ukraine, Hungary, Bulgaria
Edwards Lifesciences
Pacific Clinical Research Group

Completed

The SOLACE-AU Clinical Trial (SOLACE-AU)

Severe, Symptomatic Aortic Stenosis

Australia
Rabin Medical Center

Completed

Outcomes of Transcatheter Aortic Valve Implantation in Oncology Patients With Severe Aortic Stenosis (TOP-AS)

Aortic Valve Stenosis | Malignancy

Israel
Chulalongkorn University
Mahidol University; Chiang Mai University; Phramongkutklao College of Medicine... and other collaborators

Unknown

Severe Cutaneous Adverse Reactions in Thailand (ThaiSCAR)

Drug Reaction With Eosinophilia and Systemic Symptoms | Toxic Epidermal Necrolysis | Acute Generalized Exanthematous Pustulosis | Steven-Johnson Syndrome | Generalized Bullous Fixed Drug Eruption

Thailand
Medtronic Cardiovascular

Completed

Clinical Evaluation of MDT-2111 in Subjects With Symptomatic Severe Aortic Stenosis

Aortic Valve Stenosis

Japan
Abbott Medical Devices

Withdrawn

Assessment of St Jude Medical Portico Re-sheathable Transapical Aortic Valve System (Portico TA EU)

Severe Symptomatic Aortic Stenosis

United Kingdom
Daiichi Sankyo, Inc.
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company

Completed

Combination of Olmesartan and Hydrochlorothiazide in Essential Hypertension

Essential Hypertension

Belgium, Germany, Netherlands, Slovakia

Search clinical trials for: severe eosinophilic asthma, late-onset, fixed obstruction

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