Search clinical trials for: sustained deep molecular response

Total 110935 results

Pfizer

Recruiting

A Study to Learn About the Study Medicine Called PF-07220060 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment

Advanced or Metastatic Breast Cancer

United States, Taiwan, Canada, Japan, China, Korea, Republic of, Israel, Argentina, Mexico, Australia, Brazil, United Kingdom, India
Assiut University

Recruiting

Effect of DM on Outcomes and Response Rate in Patients With Advanced NSCLC on ICI (NSCLC)

Diabetes Mellitus | Non Small Cell Lung Cancer Metastatic

Egypt
University of Oulu

Recruiting

Video Assisted Study of Salbutamol Response in Viral Wheezing (ViVi)

Wheezing

Finland
Takeda

Recruiting

A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)

Ulcerative Colitis

United States, Canada
Assiut University

Not yet recruiting

Magnesium Sulfate in Surgical Stress Attenuation Postoperative Sore Throat and Stress Response Induced Tracheal Intubation (Magnesium)

Anesthesia Intubation Complication | Anesthesia Complication
Xu Li
LanZhou University; The Affiliated Nanjing Drum Tower Hospital of Nanjing University... and other collaborators

Not yet recruiting

Nafamostat Mesilate in the Treatment of Severe Infection-associated Coagulopathy (NMSICRCT)

Sepsis | Sepsis-induced Coagulopathy | Nafamostat Mesilate
Merck Sharp & Dohme LLC

Recruiting

A Study of Bomedemstat (IMG-7289/MK-3543) Compared to Best Available Therapy (BAT) in Participants With Essential Thrombocythemia and an Inadequate Response or Intolerance of Hydroxyurea (MK-3543-006)

Essential Thrombocythemia

Poland, Israel, Australia, Hong Kong, Japan, New Zealand, Taiwan, Korea, Republic of, United States, Spain, Italy, Netherlands, Germany
Algemeen Ziekenhuis Maria Middelares

Recruiting

Goal-directed Fluid Therapy During Deep Inferior Epigastric Perforator (DIEP) Free Flap Breast Reconstruction (GDFT DIEP-flap)

Hypotension During Surgery

Belgium
HonorHealth Research Institute
University of Arizona; Agenus Inc.; Translational Genomics Research Institute

Not yet recruiting

The Seven Trial: Exploiting the Unfolded Protein Response

Pancreatic Cancer Metastatic | Pancreatic Adenocarcinoma Metastatic

United States
Shandong University
Shandong Provincial Hospital

Recruiting

Population Pharmacokinetic of Piperacillin/Tazobactam in Maternal and Neonatal Populations

Early-Onset Neonatal Sepsis

China
National Taiwan University Hospital

Recruiting

Metabolic Mechanisms of the Electrophysiological Biomarkers for Response to Methylphenidate Treatment in Children With ADHD

Metabolomics | Methylphenidate

Taiwan
Alta Bates Summit Medical Center

Recruiting

Ketamine for MS Fatigue

Multiple Sclerosis

United States
University of Florida

Recruiting

Methylphenidate and Response to Alcohol Cues

Attention Deficit Hyperactivity Disorder | Alcohol Use Disorder

United States
Ankara City Hospital Bilkent

Recruiting

Comparison of the Efficacy of Paracetamol and Ibuprofen in the Management of Fever in Sepsis Patients

Sepsis | Fever | Acetaminophen | Ibuprofen

Turkey
CymaBay Therapeutics, Inc.

Recruiting

IDEAL: Intended to Determine the Effects of Seladelpar on Normalization of Alkaline Phosphatase Levels in Subjects With Primary Biliary Cholangitis (PBC) and an Incomplete Response or Intolerance to Ursodeoxycholic Acid (UDCA) (IDEAL)

Primary Biliary Cholangitis

United States
University of Rochester

Not yet recruiting

Efficacy of Methylene Blue Photodynamic Therapy for Treatment of Deep Tissue Abscesses

Abscess

United States
Celgene
Bristol-Myers Squibb

Recruiting

A Study to Compare the Efficacy and Safety of Idecabtagene Vicleucel With Lenalidomide Maintenance Therapy Versus Lenalidomide Maintenance Therapy Alone in Adult Participants With Newly Diagnosed Multiple Myeloma Who Have Suboptimal Response After Autologous Stem Cell Transplantation (KarMMa-9)

Multiple Myeloma

Austria, Denmark, United States, Spain, Australia, Japan, France, Korea, Republic of, Israel, Italy, Canada, Greece, Belgium, Norway, Romania, United Kingdom, Czechia, Germany, Poland
University of Texas Southwestern Medical Center
Telix International Pty Ltd; Once Upon a Time Foundation

Recruiting

PSMA PET Response Guided SabR in High Risk Pca

Prostate Adenocarcinoma

United States
University of California, Davis

Recruiting

Investigation of Locus Coeruleus Function in Sustained Attention (LC)

Attention - no Condition is Being Assessed - Healthy Adults

United States
Instituto do Cancer do Estado de São Paulo
Libbs Farmacêutica LTDA

Recruiting

Bortezomib-based Regimen for Refractory or Relapsed Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia, in Relapse | Acute Lymphoblastic Leukemia With Failed Remission

Brazil
Shanghai East Hospital

Not yet recruiting

Droplet Digital PCR Combines With Transcriptome Analysis in Early Warning of Sepsis in the Emergency Department

Sepsis | Emergent Infections, Treatment
Assiut University

Recruiting

Intravenous Anesthesia by Targeted Controlled Infusion Versus Inhalational Anesthesia on the Surgical Stress Response

Total Intravenous Anesthesia | Inhalational Anesthesia | Surgical Stress Response | Target-controlled Infusion

Egypt
Emory University

Recruiting

Systems Biological Assessment of Statin Effect on Vaccine Responses

Vaccine Response

United States
General University Hospital, Prague

Recruiting

Molecular Markes of Fibrosis of Endometriosis and Their Use in Predicting Disease Severity (MMF)

Molecular Markers of Fibrosis of Single Types of Endometriosis and Their Use in Predicting Disease Severity

Czechia
Hangzhou Highlightll Pharmaceutical Co., Ltd

Recruiting

A Phase 3 Study Comparing TLL-018 to Tofacitinib in RA Subjects With Inadequate Response or Intolerance to bDMARDs (TARA)

Rheumatoid Arthritis

China
Jip Groen
InBiome

Recruiting

Molecular Culture for the Diagnosis of Pediatric Sepsis (CHAMPIONS)

Sepsis | Microbial Colonization | Infection, Bacterial | Antibiotic Side Effect | Sepsis Bacterial | Sepsis, Neonatal

Netherlands
Odense University Hospital
Novo Nordisk A/S; Odense Patient Data Explorative Network

Recruiting

Senolytics to Improve Osteoporosis Therapy (SENIOR)

Osteopenia, Osteoporosis

Denmark
Alexion Pharmaceuticals, Inc.

Not yet recruiting

Mitigate Immune-Mediated Loss of Therapeutic Response to Asfotase Alfa (STRENSIQ®) for Hypophosphatasia (RESTORE)

Hypophosphatasia
David Escobar
The Cleveland Clinic

Recruiting

Personalized Real-Time DBS and PD Mechanisms

Parkinson Disease

United States
Roswell Park Cancer Institute

Recruiting

EGF-Depleting Therapy CIMAvax-EGF in Combination With Standard Therapy for RAS- and BRAF Wild-Type Metastatic Colorectal Cancer

Colo-rectal Cancer

United States
National Cancer Institute, Egypt

Recruiting

Low Dose Versus High Dose Methylene Blue in Septic Patients

Septic Shock

Egypt
Wuhan Union Hospital, China

Recruiting

68Ga-FAPI-04 PET Imaging in Early Response Evaluation of Rectal Cancer Patients Treated With Immunotherapy

Rectal Cancer

China
Chinese Medical Association

Recruiting

Elevated Initial APRI Value Was Associated With SALD

Liver Dysfunction | Sepsis-associated Liver Dysfunction

China
Cees Tack

Not yet recruiting

Role of Adrenaline in in the Inflammatory Response in Diabetes (RAID)

Hypoglycemia | Diabetes type1 | Inflammatory Response

Netherlands
Jun Guo

Not yet recruiting

Fluzoparib in Combination With Camrelizumab and Temozolomide in Advanced Melanoma

Melanoma
Shandong University
Shandong Provincial Hospital; Qianfoshan Hospital; Jining Medical University; Yantai... and other collaborators

Recruiting

Model-based Dose Versus Empirical Dose of Piperacillin/Tazobactam in Preterm Neonates With Late-onset Sepsis. (PIP/TAZO)

Late-Onset Neonatal Sepsis

China
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Recruiting

Efficacy, Safety, and PK of M5717 in Combination With Pyronaridine as Chemoprevention in Adults and Adolescents With Asymptomatic Plasmodium Falciparum Infection (CAPTURE-2)

Malaria Infection

Kenya, Burkina Faso, Gambia, Zambia
University Hospital, Basel, Switzerland

Recruiting

Effect of Ketanserin, Olanzapine, and Lorazepam After LSD Administration on the Acute Response to LSD in Healthy Subjects (LBL)

Healthy

Switzerland
University of Wisconsin, Madison
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

HYPEROXIA Responses and ROS

Cerebrovascular Disorders

United States
Fondazione Policlinico Universitario Agostino Gemelli...
Fundacion Clinic per a la Recerca Biomédica; Newcastle University; University...

Recruiting

Dissecting the Cellular and Molecular Atlas of Rheumatoid Arthritis in Sustained Remission to Identify Pathways Maintaining Remission and Triggering Flares (FLARE-RA)

Rheumatoid Arthritis

Italy, Spain, United Kingdom
Hasten Biopharmaceutical Co., Ltd.

Recruiting

Efficacy and Safety of Mexartan Potassium Tablets (AZL-M) and Calcium Channel Blockers (CCB) in the Treatment of Adults With Essential Hypertension in Chinese Population: a National Multicenter, Prospective, Observational Study

Essential Hypertension

China
Minia University

Recruiting

Effect of Atorvastatin as a Renal Protection in Patients With Systemic Inflammatory Response Syndrome Using Renal Arterial Resistive Index

Renal Protection

Egypt
Harvard Medical School (HMS and HSDM)
Sangath; National Institute of Mental Health (NIMH); Massachusetts General Hospital and other collaborators

Recruiting

Improving Outcomes in Depression in Primary Care in a Low Resource Setting (OptimizeD)

Depressive Disorder | Depression

India
Indonesia University

Recruiting

Comparison of Plasma Neutrophil Gelatinase-Associated Lipocalin (pNGAL) Level in De-resuscitation With Furosemide Group and Control Group

Acute Kidney Injury Due to Sepsis

Indonesia
Menoufia University

Recruiting

Hemodynamic Responses of Dexmedetomidine, Lidocaine or Propofol Infusions During Laparoscopic Cholecystectomy

Dexmedetomidine | Laparoscopic Cholecystectomy | Propofol | Lidocaine | Hemodynamic Responses

Egypt
Chinese PLA General Hospital

Recruiting

Efficiency and Safety of Paxlovid for COVID-19 Patients With Severe Chronic Kidney Disease (ESPTCSCKD)

COVID-19 | Renal Insufficiency, Chronic

China
Federico II University

Recruiting

Evaluation of Main Determinants of Postprandial Glucose Response in Type 1 Diabetes (IN-DEEP)

Type 1 Diabetes

Italy
Rambam Health Care Campus

Recruiting

Evaluating Bronchodilator Response in Patients With Bronchiectasis

Bronchiectasis | Cystic Fibrosis | Bronchiolitis Obliterans | Primary Ciliary Dyskinesia | Primary Immune Deficiency

Israel
National Institute of Allergy and Infectious Diseases...

Recruiting

Effect of Bismuth Subsalicylate on the Gut Microbiome and Host Response in Healthy Adults

Healthy Adults

United States
Odense University Hospital

Recruiting

Early Initiated Vasopressor Therapy in the Emergency Department (VASOSHOCK)

Shock | Shock, Septic | Hypotension | Hypovolemia | Hypotension and Shock | Hypovolemic Shock | Hypotension Symptomatic | Hypovolemic

Denmark

Search clinical trials for: sustained deep molecular response

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