Search clinical trials for: Repurposed drugs

Total 257985 results

Pfizer

Completed

Six Month Clinical Trial Assessing Efficacy And Safety Of Inhaled Insulin In Type 1 Diabetes Mellitus.

Diabetes Mellitus, Type 1

United States, Canada
Cubist Pharmaceuticals LLC

Terminated

HepeX-B in Post Hepatic Allografts for Treatment of End Stage Liver Disease Due to Hepatitis B Infection

Liver Transplantation | Hepatitis B

New Zealand, United States, Israel, United Kingdom, France, Germany, Spain
Pfizer
Sanofi; Nektar Therapeutics

Completed

Effect on Glycemic Control of Inhaled Insulin Alone or Added to Dual Oral Therapy After Failure of Dual Oral Therapy.

Diabetes Mellitus, Type 2

United States, Canada
Pfizer

Completed

Six Month Clinical Trial Assessing Efficacy And Safety Of Inhaled Insulin In Type 2 Diabetes

Diabetes Mellitus, Type 2

United States, Canada
Innovative Medical

Completed

Efficacy of Topical Cyclosporine 0.05% in the Prevention of Ocular Surface Inflammation Secondary to Pterygia

Pterygia

United States
Laserklinik Karlsruhe

Completed

Comparative Study of the Effect of Dysport and Botox

Aging

Germany
Pfizer

Completed

Six Month Clinical Trial Assessing Efficacy and Safety of Inhaled Insulin in Type 1 Diabetes

Diabetes Mellitus, Type 1

United States, Canada
Eli Lilly and Company

Completed

Comparison of LY686017 With a Marketed Drug in the Treatment of Social Anxiety Disorder

Social Phobia

United States
Heidelberg University
Dietmar Hopp Stiftung; Prof. Wolfgang Stremmel

Completed

Dose Finding Study for Retarded Phosphatidylcholine in Pancolitis

Ulcerative Colitis

Germany
Medical University of Vienna

Completed

Effects of Topical Clonidine vs. Brimonidine on Choroidal Blood Flow and Intraocular Pressure During Isometric Exercise

Ocular Physiology | Regional Blood Flow

Austria
Medical University of Vienna

Completed

Effects of Indomethacin on Retinal and Choroidal Blood Flow in Healthy Volunteers

Ocular Physiology | Regional Blood Flow

Austria
POZEN

Completed

To Evaluate the Safety and Efficacy of Trexima in the Acute Treatment of Migraine Headaches

Migraine Headaches

United States
Abant Izzet Baysal University

Unknown

A Study Evaluating the Effects of Lipid Lowering Treatment on Steroid Synthesis

Diabetes Mellitus | Hypercholesterolemia | Coronary Heart Disease | Non-Coronary Atherosclerotic Disease

Turkey
POZEN

Completed

To Evaluate the Safety and Efficacy of Trexima in the Acute Treatment of Migrane Headaches

Migraine Headaches

United States
University of Calgary
Canadian Institutes of Health Research (CIHR); LEO Pharma; Dupont Applied Biosciences

Completed

Trial of the Effect of Low-Molecular-Weight Heparin (LMWH) Versus Warfarin on Mortality in the Long-Term Treatment of Proximal Deep Vein Thrombosis (DVT) (Main LITE Study)

Thrombosis | Venous Thrombosis | Thromboembolism

Canada
AstraZeneca

Completed

SAKK - a Trial to Evaluate Antitumor Efficacy of Faslodex® After Aromatase Inhibitor Failure in Advanced Breast Cancer

Breast Neoplasms

Belgium, Switzerland
Aga Khan University

Completed

Efficacy of L-Ornithine-L-Aspartate in Cirrhotics With Hepatic Encephalopathy

Hepatic Encephalopathy

Pakistan
University of Calgary
Canadian Institutes of Health Research (CIHR); LEO Pharma; Dupont Applied Biosciences

Completed

Assessment of Long-Term Out-of-Hospital Treatment of Patients With Proximal Deep Vein Thrombosis (DVT) Using Low-Molecular-Weight Heparin (LMWH) Versus LMWH Followed by Warfarin

Thrombosis | Venous Thrombosis | Thromboembolism

Canada
Semmelweis University

Unknown

Autoimmunity in Retinitis Pigmentosa

Retinitis Pigmentosa

Hungary
Innovative Medical

Completed

Bimatoprost Monotherapy vs. Dual Therapy With Travoprost and Timolol in Patients With Glaucoma and Ocular Hypertension

Glaucoma

United States
The New England Center for Headache, P.C.
Ortho-McNeil Neurologics, Inc.

Unknown

Detoxification and Treatment of Subjects With Medication Overuse Headache

Analgesic Rebound Headache

United States
Charite University, Berlin, Germany
Hoffmann-La Roche

Unknown

Open Label Clinical Trial With Rituximab (MabThera ®) in Ankylosing Spondylitis

Ankylosing Spondylitis

Germany
National Center for Complementary and Integrative...

Completed

Herb-Opioid Interactions

Pain

United States
Abbott

Completed

The Safety and Efficacy of Divalproex Sodium Extended-Release Tablets in Migraine Prophylaxis: A Study in Adolescents

Migraine

United States
University Medical Center Groningen

Unknown

Dry Powder Inhalation of Cyclosporine A in Lung Transplant Patients With Bronchiolitis Obliterans Syndrome

Bronchiolitis Obliterans | Lung Transplantation

Netherlands
Critical Therapeutics

Unknown

Study of Oral Zileuton in the Treatment of Moderate to Severe Facial Acne Vulgaris

Acne Vulgaris

United States
Tata Memorial Hospital

Completed

Does Tranexamic Acid Administration Reduce Blood Loss During Head and Neck Surgery?

Head and Neck Neoplasms

India
Radboud University Medical Center
Netherlands Brain Foundation; Netherlands Alzheimer Foundation; American Health...

Completed

Effect of Indomethacin on the Progression of Alzheimer's Disease

Alzheimer Disease

Netherlands
Psychiatric Hospital, Hillerod
Amager Hospital; Psychiatric Center Ballerup; Psychogeriatric Unit, CU Hospital... and other collaborators

Terminated

Treatment of Depression in the Elderly

Depression

Denmark
Medical University of Vienna

Completed

Effect of Elevated Plasma-Free-Fatty-Acids on Renal Hemodynamic Parameters

Glomerular Filtration Rate | Fatty Acids, Nonesterified | Renal Circulation | Renal Plasma Flow

Austria
University Hospital Muenster
Hoffmann-La Roche

Completed

Azathioprine or Mycophenolate Mofetil for Bullous Pemphigoid

Bullous Pemphigoid

Germany
Jacobus Pharmaceutical

Terminated

Efficacy of Dapsone as a Steroid Sparing Agent in Pemphigus Vulgaris

Pemphigus Vulgaris

United States
Medical University of Vienna

Completed

Mechanisms of Choroidal Blood Flow Changes During Dark/Light Transitions

Ocular Physiology | Regional Blood Flow

Austria
Ludwig-Maximilians - University of Munich

Unknown

Niacin As Secondary Prevention Of Coronary Artery Disease (NASPOCAD)

Coronary Artery Disease

Germany
Henogen

Completed

Evaluation of Safety, Immune-Response and Efficacy of GSK Biologicals' EBV (Epstein Barr Virus) Vaccine (268664).

Epstein Barr Virus (EBV) Infection

Belgium
Charles University, Czech Republic
AstraZeneca

Unknown

CHANCE - Candesartan in Hypertrophic Cardiomyopathy

Hypertrophic Cardiomyopathy

Czech Republic
Postgraduate Institute of Medical Education and...

Unknown

A Comparative Study of the Safety and Efficacy of Face Talc Slurry and Iodopovidone for Pleurodesis

Primary Spontaneous Pneumothorax | Malignant Pleural Effusions | Recurrent Pleural Effusions | Secondary Spontaneous Pneumothorax

India
Barwon Health
National Health and Medical Research Council, Australia; University of Melbourne

Completed

Thyroid-Associated Ophthalmopathy Subtypes and Orbital Antibodies

Graves' Ophthalmopathy

Australia
University of Cambridge
British Heart Foundation

Unknown

Double Blind Crossover Comparison of Diuretics in the Young

Low-Renin Hypertension

United Kingdom
Hospital de Clinicas de Porto Alegre

Completed

Effect of Nutritional Intervention on the Lipid Profile of HIV-Positive Patients Who Start HAART: a Randomized Trial

HIV Infections

Brazil
Icahn School of Medicine at Mount Sinai
Allergan

Completed

BOTOX® Versus Zanaflex® for the Treatment of Post-Stroke or Traumatic Brain Injury Upper Limb Spasticity

Upper Limb Spasticity
Hadassah Medical Organization

Unknown

Assessment of Asymptomatic Heart Disease in Children With HIV

HIV Infections

Israel
Robert Bosch Gesellschaft für Medizinische Forschung...

Terminated

Improved Estimation of GFR by Cystatin C in Preventing Contrast Induced Nephropathy by NAC or Zn

Chronic Kidney Failure

Germany
Hospital Mutua de Terrassa
Fondo de Investigacion Sanitaria

Terminated

Ceftriaxone Vs Levofloxacin on Cytokine Expression in Pneumococcal Pneumonia

Pneumonia, Pneumococcal

Spain
Cambridge University Hospitals NHS Foundation Trust

Completed

Pulse Versus Continuous Cyclophosphamide for Induction of Remission in ANCA-Associated Vasculitides

Wegener's Granulomatosis | Microscopic Polyangiitis | ANCA Associated Systemic Vasculitis
University of New Mexico
GlaxoSmithKline

Completed

A RCT of Ondansetron and Promethazine in the Treatment of Nausea and Vomiting in the Emergency Department

Nausea | Vomiting

United States
Instituto Nacional de Cancerologia de Mexico

Unknown

Treatment of Good Prognosis, BCL-6 Negative Diffuse Large Cell Lymphoma With CHOP-R in Patients < 61 Years Old.

Non-Hodgkin Lymphoma

Mexico
Astellas Pharma Inc

Completed

Phase 3 Study of Tacrolimus (FK506) for Lupus Nephritis: A Placebo Controlled, Double-Blind Multicenter, Comparative Study

Lupus Nephritis

Japan
Hadassah Medical Organization

Unknown

Effect Of Nicotine on Neurocognitive Performance of Cigarette Smokers

Smoking | Tobacco Use Disorder | Nicotine Dependence | Nicotine Use Disorder

Israel
The Cleveland Clinic
Sanofi

Completed

Assessment of Cardioversion Using Transesophageal Echocardiography II (ACUTE II)

Atrial Fibrillation

United States

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