Search clinical trials for: Drug toxicity

Total 261199 results

Tobinick, Edward Lewis, M.D.

Completed

TNF-Alpha Inhibition for Treatment of Alzheimer's Disease

Alzheimer's Disease

United States
Center for Epidemiology and Health Research, Germany

Completed

Case-Control Study on Analgesics and Nephropathy (SAN)

Kidney Failure, Chronic

Germany
University of Edinburgh
Pfizer

Completed

Effect of Regular Sildenafil on Blood Pressure and Arterial Function in Hypertension

Hypertension

United Kingdom
National Institute on Deafness and Other Communication...

Terminated

Autoimmunity in Inner Ear Disease

Hearing Loss, Sensorineural

United States
Bichat Hospital

Completed

Cough Reflex and Obstructive Sleep Apnea Syndrome

Sleep Apnea Syndrome

France
Bavarian Nordic

Completed

Take Rate, Immunogenicity and Safety of Elstree-BN Smallpox Vaccine in Healthy Vaccinia-Naive Subjects

Smallpox

Germany
Hokkaido Gastrointestinal Cancer Study Group

Terminated

Feasibility Study of mFOLFOX6 in Patients With Advanced Colorectal Cancer

Colorectal Cancer

Japan
Hokkaido Gastrointestinal Cancer Study Group

Completed

Phase I/II Study of Oral S-1 Plus Irinotecan in Patients With Advanced Gastric Cancer

Gastric Cancer
Purdue Pharma LP

Completed

Safety of the Buprenorphine Transdermal Delivery System in Subjects With Mod-to-Sev Pain Following Orthopedic Surgery.

Postoperative Pain

United States
Harras Pharma Curarina GmbH

Completed

Long-Term Effects of Sucontral(TM) on Mild and Moderate Cases of Diabetes Mellitus (Type 2)

Diabetes Mellitus, Type 2

Slovakia
Zivena

Unknown

Inhaled Doxorubicin Plus IV Docetaxel and Cisplatin in Patients With Non-Small-Cell Lung Carcinoma (NSCLC)

NSCLC

United States
Radboud University Medical Center
Netherlands Heart Foundation

Completed

VITRO-Trial. B Vitamins and the Secondary Prevention of Venous Thrombosis

Pulmonary Embolism | Deep-Vein Thrombosis

Netherlands
Otsuka Pharmaceutical Development & Commercialization...

Completed

Aripiprazole Pharmacokinetics (PK) and Tolerability Study in Children and Adolescents

Schizophrenia | Mania
University Hospital, Bonn

Unknown

Risperidone-Induced Hyperprolactinemia Treated With Bromocriptine

Schizophrenia | Hyperprolactinemia

Germany
Assistance Publique - Hôpitaux de Paris
European Georges Pompidou Hospital; Clinical Research Unit; Direction Régionale...

Completed

KETOR: Effects of Peri Operative Administration of Ketamine on Long Term Post Thoracotomy Pain

Pain | Neuralgia | Thoracotomy | Ketamine | Chronic Post Thoracotomy Pain

France
The Kennedy Institute-National Eye Clinic
Sygekassernes Helsefond

Completed

Study of BH4, a New and Simple Treatment of Mild PKU

Phenylketonuria

Denmark
Bukwang Pharmaceutical

Terminated

Safety and Antiviral Activity of Clevudine in Patients Infected With Hepatitis B Virus

Hepatitis B

Korea, Republic of
Celgene Corporation
Prologue Research International

Terminated

Phase I/II Open-Label, Dose Escalation Study To Determine The Maximum Tolerated Dose And To Evaluate The Safety Profile of Lenalidomide (Revlimid® CC-5013) With Liposomal Doxorubicin In Subjects With Advanced Ovarian and Primary Peritoneal Carcinoma

Ovarian Cancer

United States
Université de Sherbrooke
Canadian International Development Agency

Completed

Study of the Management of Vaginal Discharge in West African Using Single Dose Treatments

Candidiasis | Vaginitis | Bacterial Vaginosis

Ghana, Guinea, Togo
North Eastern German Society of Gynaecological...

Completed

Topotecan Vs. Topotecan + Etoposide Vs.Topotecan + Gemcitabine in Ovarian Cancer Therapy

Ovarian Cancer

Germany
Assistance Publique - Hôpitaux de Paris

Terminated

IMPROVE: Mycophenolate Mofetil Versus Azathioprine for Maintenance Therapy in ANCA Associated Systemic Vasculitis

ANCA Associated Systemic Vasculitis Including Wegener's | Granulomatosis and Microscopic Polyangiitis and | Renal Limited Vasculitis

France, United Kingdom
Veterans Affairs Medical Center, Miami
Abbott

Unknown

Compare Tolerability of an Overnight Switch to Gradual Switch Between Two Different Forms of Depakote

Epilepsy | Behavioral Disturbance

United States
NHS Greater Glasgow and Clyde

Completed

Effects of Eplerenone on Left Ventricular Remodelling Following Heart Attack

Myocardial Infarction

United Kingdom
Medical University of Vienna

Completed

Effect of High-Dose Prednisolone (Solu Dacortin®) Treatment on Choroidal and Optic Nerve Head Blood Flow in Humans

Regional Blood Flow | Optic Disk

Austria
Maisonneuve-Rosemont Hospital
Hippocrate Research & Development

Unknown

Gleevec Administered Preoperatively to Reduce Gastrointestinal Stromal Tumor (GIST)

Gastrointestinal Stromal Tumors

Canada
Steno Diabetes Center Copenhagen
Bayer

Completed

Renoprotective Effect of Nisoldipine and Lisinopril in Type 1 Diabetic Nephropathy

Diabetic Nephropathy

Denmark
Swedish Heart Lung Foundation
The Council for Medical Health Care Research in South Sweden; The Malmö University... and other collaborators

Completed

Trial of an Interactive CD-Program on 6 Months Readmission Rate in Patients With Heart Failure

Heart Failure

Sweden
University Hospital, Gentofte, Copenhagen

Unknown

Melatonin Treatment and Inflammation, Oxidative Stress and Autonomic Function in Connection With Surgery

Oxidative Stress | Myocardial Ischaemia | Inflammatory Stress

Denmark
University of Wuerzburg

Unknown

VELCADE as Maintenance Treatment in Patients With Multiple Myeloma Following Autologous Peripheral Blood Stem Cell Transplantation (PBSCT)

Multiple Myeloma

Austria, Germany, Italy
The Netherlands Asthma Foundation

Completed

Asthma, a Disease Due to a Lack of Bacterial Infections in Childhood.

Asthma | Rhinitis | Atopic Dermatitis | Food Allergy

Netherlands
Chinese University of Hong Kong

Unknown

Effect of Growth Hormone in Metabolic Syndrome

Metabolic Syndrome

China
Bamrasnaradura Infectious Diseases Institute

Completed

Nevirapine Levels and Fluconazole

Adverse Event | Nevirapine | Fluconazole
Austrian Breast & Colorectal Cancer Study Group

Terminated

Randomized Study on Neoadjuvant Radio-Chemotherapy in Rectal Carcinoma Dukes B and C

Rectal Cancer Dukes B, Dukes C

Austria
Assistance Publique - Hôpitaux de Paris

Unknown

Local Anesthesia and Tuberculin Skin Test in Infants and Children

Tuberculosis

France
University Health Network, Toronto

Completed

Intravenous Immune Globulin Treatment Compared to Placebo in Patients With Myasthenia Gravis

Myasthenia Gravis

Canada
Austrian Breast & Colorectal Cancer Study Group

Completed

Randomized Trial on Adjuvant Chemotherapy in Colon Carcinoma Dukes B

Colon Cancer Stage II

Austria
Samaritan Pharmaceuticals, Inc

Completed

A Dose Response and Safety Study of Procaine HCl in HIV-Infected Patients

HIV Infections

United States
Massachusetts General Hospital

Completed

Study of Sildenafil in Patient With Heart Failure.

Congestive Heart Failure

United States
Astellas Pharma Inc
Astellas Pharma US, Inc.

Completed

A Study to Evaluate the Effects of YM872 on Brain Function and Disability When Administered in Combination With Alteplase (Tissue Plasminogen Activator)

Acute Ischemic Stroke

Canada, United States, Germany, Belgium, Austria
Austrian Breast & Colorectal Cancer Study Group

Completed

Randomized Study on Adjuvant Chemotherapy and Adjuvant Chemo-Immunotherapy in Colon Carcinoma Dukes C

Colon Cancer Stage III

Austria
PICS, Inc.
National Heart, Lung, and Blood Institute (NHLBI)

Unknown

A Treatment Study Comparing Two Non-Drug, Self-Help Treatment of Chronic Insomnia.

Insomnia

United States
Eunice Kennedy Shriver National Institute of Child...

Unknown

The Effect of Thyroid Hormone Levels in Pregnant Women on the Intelligence Quotient (IQ) of Their Children

Pregnancy | Subclinical Hypothyroidism | Child Development Disorders

United States
Taichung Veterans General Hospital

Unknown

Tranexamic Acid and Head and Neck Surgery Patients

Head and Neck Neoplasms

Taiwan
National Taiwan University Hospital

Unknown

Pancreatic Islet Function, Insulin Sensitivity, and Chronic Complications in Pre-Diabetes

Obesity | Prediabetic State | Metabolic Syndrome X

Taiwan
Hamamatsu University
Maruyama Memorial General Hospital; Seirei Hamamatsu General Hospital; Iwata... and other collaborators

Completed

Study of the Relationship Between rHuEPO Dose, Serum ADPN, and Mortality in Patients Beginning Hemodialysis (HD)

Renal Dialysis
National Taiwan University Hospital

Unknown

The Role of Lymphangiogenesis in Head and Neck Cancer Metastasis

Laryngeal Cancer | Hypopharyngeal Cancer | Oral Cancer

Taiwan
Nathan Kline Institute for Psychiatric Research
Research Foundation for Mental Hygiene, Inc.; Janssen, LP

Completed

Risperidone Alone Vs. Risperidone Plus Valproate in the Treatment of Patients With Schizophrenia and Hostility

Schizophrenia

United States
Nutrition 21, Inc.

Completed

A 30 Day Acute Efficacy and Safety Study of Chromium Picolinate + Biotin on Glycemic Control in Overweight or Obese Subjects With T2DM

Diabetes Mellitus, Type 2

United States
National Taiwan University Hospital

Unknown

The Roles of Cytokines in the Mechanism of Insulin Resistance and Energy Balance

Insulin Resistance | Cachexia | Metabolic Syndrome X

Taiwan
University of Shizuoka

Completed

The Effect of CoQ10 Administration on Hemodialysis Patients

Hemodialysis | Chronic Renal Failure

Japan

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