Search clinical trials for: Investigational drug

Total 263061 results

Eunice Kennedy Shriver National Institute of Child...
Children's National Research Institute

Terminated

Phase I Pilot Study of Liver-Directed Gene Therapy for Partial Ornithine Transcarbamylase Deficiency

Ornithine Transcarbamylase Deficiency Disease
National Center for Research Resources (NCRR)
Scripps Clinic

Completed

Phase II Pilot Study of Cladribine (2-Chlorodeoxyadenosine; 2-CdA) for Early Stage Primary Sclerosing Cholangitis

Cholangitis, Sclerosing
Hoffmann-La Roche

Completed

Treatment of Psoriasis Using Acitretin in HIV-Positive Patients

HIV Infections | Psoriasis

United States
XOMA (US) LLC

Completed

Safety and Efficacy of a Monoclonal Antibody for Treatment of Rheumatoid Arthritis.

Rheumatoid Arthritis

United States
Merck Sharp & Dohme LLC

Unknown

Safety and Effectiveness of Giving Indinavir, Ritonavir, Stavudine, and Lamivudine to HIV-Infected Patients Who Have Never Received Anti-HIV Drugs

HIV Infections

United States
National Center for Research Resources (NCRR)
Baylor College of Medicine

Unknown

Gluconeogenesis in Very Low Birth Weight Infants Who Are Receiving Nutrition By Intravenous Infusion

Hyperglycemia | Infant, Low Birth Weight

United States
Shaman Pharmaceuticals

Completed

SP-303T Applied to the Skin of Patients With Herpes Simplex Virus (HSV) Infection and AIDS Who Have Not Had Success With Acyclovir

HIV Infections | Herpes Simplex

United States
Schering-Plough

Completed

Safety and Effectiveness of Fluconazole Versus SCH 56592 to Treat Thrush in HIV-Positive Patients

HIV Infections | Candidiasis, Oral

United States, Barbados
Liposome

Completed

Safety and Efficacy of Amphotericin B Lipid Complex in the Treatment of Cryptococcal Meningitis in Patients With the Acquired Immunodeficiency Syndrome

HIV Infections | Meningitis, Cryptococcal

United States
Novartis

Completed

Safety and Effectiveness of Giving Lamisil to HIV-Positive Subjects With Thrush Who Have Not Responded to Fluconazole Treatment

HIV Infections | Candidiasis, Oral

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Phase I Safety and Immunogenicity Trial of UBI SynVac (HIV-1 MN Octameric V3 Peptide Vaccine)

HIV Infections

United States
Jacobus Pharmaceutical

Completed

A Comparison of Dapsone and Trimethoprim-Sulfamethoxazole in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
Boehringer Ingelheim

Completed

A Multi-Center, Placebo-Controlled, Double-Blind, Randomized Trial Comparing the Virologic and Immunologic Activities of 400 Mg Nevirapine in Combination With Zidovudine Versus Zidovudine Alone in Asymptomatic HIV-1 Infected Patients With 4-12 Months of Prior Zidovudine Therapy and 200-500 CD4+ Cell

HIV Infections

United States
Glaxo Wellcome

Completed

The Safety and Effectiveness of Lamivudine Plus Zidovudine, Used With and Without 1592U89, in HIV-1 Infected Patients Who Have Never Taken Anti-HIV Drugs

HIV Infections

United States, Canada, Puerto Rico
Sequus Pharmaceuticals

Completed

A Study of DOX-SL in the Treatment of AIDS-Related Kaposi's Sarcoma

HIV Infections | Sarcoma, Kaposi

United States
National Center for Research Resources (NCRR)
University of Michigan

Completed

Study of Zinc for Wilson Disease

Wilson Disease

United States
Glaxo Wellcome

Completed

A Study of Increased Lactic Acid and Abnormal Fat Distribution in HIV-Positive Patients

HIV Infections | Lipodystrophy

United States
PharmaResearch

Unknown

Comparing Side Effects of Two Forms of Videx in HIV-Infected Adults

HIV Infections

United States
National Institute on Aging (NIA)

Completed

Multicenter Trial of Prednisone in Alzheimer's Disease

Alzheimer Disease

United States
National Institute of Allergy and Infectious Diseases...
Schering-Plough

Completed

SCH 39304 as Therapy for Acute Cryptococcal Meningitis in HIV-Infected Patients Followed by Maintenance Therapy

HIV Infections | Meningitis, Cryptococcal

United States
Dupont Merck

Completed

A Study of Efavirenz in Combination With Stavudine and Didanosine

HIV Infections

United States
Hoffmann-La Roche

Completed

The Safety and Effectiveness of Saquinavir Soft Gelatin Capsules Combined With Other Anti-HIV Drugs

HIV Infections

United States
Agouron Pharmaceuticals

Completed

Viracept Expanded Access Program

HIV Infections

United States
Ortho Pharmaceuticals

Completed

A Double-Blind, Placebo-Controlled Study With Open-Label Follow-Up To Determine the Safety and Efficacy of Subcutaneous Doses of r-HuEPO in AIDS Patients With Anemia Induced by Their Disease and AZT Therapy

HIV Infections | Cytopenias

United States
Fairview University Medical Center

Completed

Study of Allogeneic Bone Marrow Transplantation Following Cyclophosphamide and Radiotherapy in Patients With Myelodysplastic Syndrome and Acute Leukemia Related to Fanconi's Anemia

Myelodysplastic Syndromes | Leukemia, Lymphocytic, Acute | Fanconi's Anemia | Leukemia, Nonlymphocytic, Acute

United States
Genentech, Inc.

Completed

A Phase I Study of the Safety and Immunogenicity of Rgp 120/HIV-1IIIB Vaccine in HIV-1 Seropositive Adult Volunteers

HIV Infections

United States
Glaxo Wellcome

Completed

A Dose-Frequency Trial of Oral Retrovir in Patients With AIDS or Severe ARC

HIV Infections

United States
Newport Pharmaceuticals International

Completed

A Double-Blind Placebo Controlled Study To Determine the Optimal Immunopharmacological Dose Level of Isoprinosine in Immunodepressed Volunteers

HIV Infections

United States
AJI Pharma USA

Completed

Phase I/II Study of the Tolerance and Efficacy of Combined Use of Didanosine (2',3'-Dideoxyinosine; ddI) and Lentinan in HIV-Positive Patients

HIV Infections

United States
Roche Global Development

Completed

A Randomized, Controlled Study of the Safety and Preventive Efficacy of Oral Ganciclovir When Used in Conjunction With An Intravitreal Ganciclovir Implant in the Treatment of Cytomegalovirus Retinitis

HIV Infections | Cytomegalovirus Retinitis

United States
Hoechst Marion Roussel

Completed

A Study of the Safety and Efficacy of Chronically Administered MDL 28,574A in the Treatment of HIV-Infected Patients

HIV Infections

United States
Pharmacia and Upjohn

Completed

Safety and Effectiveness of Giving Combinations of Three or Four Anti-HIV Drugs to HIV-Infected Patients

HIV Infections

United States
Ligand Pharmaceuticals

Completed

A Study of Targretin Capsules in Patients With AIDS-Related Kaposi's Sarcoma

HIV Infections | Sarcoma, Kaposi

United States
Univax Biologics Inc

Completed

A Randomized, Multicenter, Double-Blind, Parallel-Group, Placebo-Controlled Trial of the Efficacy and Safety of Bovine Anti-Cryptosporidium Immunoglobulin (BACI) in the Treatment of Cryptosporidium Enteritis in AIDS Patients

HIV Infections | Cryptosporidiosis

United States
Pharmacia

Completed

A Study of Rifabutin, Used Alone or With Ethambutol in the Prevention of Mycobacterium Avium Complex (MAC) Bacteremia in Patients With AIDS

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
National Center for Research Resources (NCRR)
Baylor College of Medicine

Unknown

Study of Treatment and Metabolism in Patients With Urea Cycle Disorders

Amino Acid Metabolism, Inborn Errors

United States
National Center for Research Resources (NCRR)
University of Texas

Unknown

Randomized Study of Testosterone and Progressive Resistance Exercise in Men With Burn Injury

Burns

United States
National Center for Research Resources (NCRR)

Unknown

Thalidomide and Dacarbazine for Metastatic Melanoma

Melanoma

United States
National Institute of Allergy and Infectious Diseases...

Terminated

Computer-Assisted Adherence Program for Patients Taking Anti-HIV Drugs

HIV Infections | Acquired Immunodeficiency Syndrome

United States
Glaxo Wellcome

Completed

A Study of Retrovir in the Prevention of HIV Infection in Health Care Workers Accidentally Exposed to the Virus

HIV Infections

United States
Interferon Sciences

Completed

Double-Blind, Randomized, Placebo-Controlled Study of Low Dose Oral Interferon Alfa-n3 (Human Leukocyte Derived) in ARC Patients

HIV Infections

United States
Mylan Laboratories

Completed

A Phase II/III Study of Cysteamine (Mercaptoethylamine) and Zidovudine for the Treatment of HIV Disease

HIV Infections

United States
National Center for Research Resources (NCRR)
University of Texas

Completed

Phase I Study of Tin Mesoporphyrin in Patients on Long Term Heme Therapy for Prevention of Acute Attacks of Porphyria

Porphyria
National Institute on Drug Abuse (NIDA)
Johns Hopkins University

Unknown

Randomized Study of Interventions to Enhance Adherence to Isoniazid Prevention Therapy for Tuberculosis in Injection Drug Users

Tuberculosis
Eunice Kennedy Shriver National Institute of Child...
National Institute of Mental Health (NIMH)

Unknown

Valproate Response in Aggressive Autistic Adolescents

Autism

United States
National Center for Research Resources (NCRR)
Stanford University

Unknown

Phase II Randomized Study of Intravenous Versus Oral Clomipramine in Patients With Obsessive Compulsive Disorder

Obsessive-Compulsive Disorder

United States
Glaxo Wellcome

Completed

The Safety and Effectiveness of Different Dose Levels of 1263W94 in the Treatment of Cytomegalovirus (CMV) of the Eyes in HIV-Infected Patients

HIV Infections | Cytomegalovirus Infections

United States
National Center for Research Resources (NCRR)
Children's Hospital Colorado

Unknown

Phase I Study of Colchicine Therapy in Childhood Hepatic Cirrhosis

Liver Cirrhosis | Cirrhosis
National Center for Research Resources (NCRR)
Genentech, Inc.

Completed

Growth Hormone Use in Cystic Fibrosis - a Multicenter Study

Cystic Fibrosis

United States
ICOS-Texas Biotechnology
ICOS Corporation; Texas Biotechnology Corporation

Unknown

Safety and Efficacy of Sitaxsentan in the Treatment of Pulmonary Arterial Hypertension

Pulmonary Hypertension

United States, Canada

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