Clinical Trials Sponsored by ActoGeniX N.V.

Total 1479 results

Disphar International B.V.

Completed

Study of Teysuno (S-1) Combined With Epirubicin and Oxaliplatin in Patients With Advanced Solid Tumors

Patients With Advanced or Metastatic Solid Tumors
Disphar International B.V.

Withdrawn

Comparative Bioavailability Study of Metformin HCl 1000 mg Granules vs Glucophage 1000 mg Film-coated Tablet

Comparative Bioavailability

Jordan
BBB-Therapeutics B.V.

Terminated

Safety, Pharmacokinetics and Pharmacodynamics Study With 2B3-201 in Healthy Subjects and Multiple Sclerosis(MS) Patients

Multiple Sclerosis | Healthy Volunteers

Netherlands
Deutsche Lungenstiftung e.V.

Terminated

Non-invasive Ventilation in Severe Chronic Obstructive Pulmonary Disease(COPD)

Chronic Obstructive Pulmonary Disease | Hypercapnia

Germany
Peterson, Noel, N.D.

Completed

Efficacy of Training in Manual Preparation of Platelet Rich Plasma

Platelet Rich Plasma Production

United States
Pharming Technologies B.V.

Completed

Recombinant Human C1 Inhibitor for the Treatment of Acute Attacks in Patients With Hereditary Angioedema

Genetic Disorders

Netherlands
Pharming Technologies B.V.

Completed

Recombinant Human C1 Inhibitor for the Treatment of Acute Attacks in Patients With Hereditary Angioedema

Hereditary Angioedema | Angioneurotic Edema

Netherlands
Pharming Technologies B.V.

Completed

Recombinant Human C1 Inhibitor for the Treatment of Acute Attacks in Patients With Hereditary Angioedema

Hereditary Angioedema | Genetic Disorders | Angioneurotic Edema

Netherlands, Romania
Janssen-Cilag B.V.

Completed

A Study of the Effectiveness and Safety of Treatment With Epoetin Alfa on Hemoglobin Levels, Red Blood Cell Transfusions, and Quality of Life in Patients With Cancer Receiving Platinum-containing Chemotherapy

Anemia | Neoplasm
Aqumen Biopharmaceuticals, N.A.

Terminated

DY002: Safety and Effectiveness of DYME as an Agent for Selective Staining of the Anterior Capsule During Cataract Surgery (AQNA-DY002)

Mature Cataracts

United States, India
Aktion Bronchialkarzinom e.V.

Completed

Randomized Phase III-Study in Stage IIIb and IV Non-Small-Cell Lung Cancer. Sequential Single-Agent vs. Double-Agent vs. Triple-Agent Therapy.

Non-Small-Cell Lung Carcinoma

Germany
Universitaire Ziekenhuizen KU Leuven
KU Leuven; Janssen Pharmaceutica N.V., Belgium

Completed

Investigation of the Role of the Microbiome in the Pathogenesis of Colorectal Adenoma and Carcinoma

Colorectal Adenoma and Carcinoma

Netherlands, Belgium
State Budgetary Healthcare Institution, National...

Enrolling by invitation

Thermocoagulation in Drug Resistant Focal Epilepsy

Epilepsy | Epilepsies, Partial | Epilepsy Intractable | Seizures, Focal

Russian Federation
State Budgetary Healthcare Institution, National...

Completed

Combination of Nivolumab and DHAP in Patients With Relapsed or Refractory Classical Hodgkin Lymphoma (Nivo-DHAP) (Nivo-DHAP)

Hodgkin Lymphoma

Russian Federation
State Budgetary Healthcare Institution, National...

Enrolling by invitation

A Cohort Prospective Study of Predictors Influencing the Quality of Visualization of the Operating Field During Orthognathic Surgery

Hemorrhage | Malocclusion | Maxillofacial Injuries | Orthodontics

Russian Federation
State Budgetary Healthcare Institution, National...

Completed

Management of Endothelial Dysfunction in Patients With Chronic Venous Insufficiency After Endovenous Surgical Procedure

Endothelial Dysfunction | Venous Insufficiency of Leg | Venous Insufficiency (Chronic)(Peripheral)

Russian Federation
State Budgetary Healthcare Institution, National...

Recruiting

First Line Chemotherapy for Classical Hodgkin Lymphoma in Russia (HL-Russia-1) (HL-Russia-1)

Hodgkin Lymphoma, Adult

Russian Federation
State Budgetary Healthcare Institution, National...

Completed

Safety and Feasibility of St. Mark's Electrode for the Hypoglossal Nerve and Cortico-lingual Pathway Study

Healthy Volunteers

Russian Federation
State Budgetary Healthcare Institution, National...

Completed

Comparative Assessment of Effectiveness and Safety of Methods for Skin and Hair Care in Severe Intensive Care Unit Patients

Pressure Ulcer

Russian Federation
State Budgetary Healthcare Institution, National...

Completed

Determination of Acute Encephalopathy Predictors in Patients With COVID-19

COVID | Encephalopathy

Russian Federation
The Leeds Teaching Hospitals NHS Trust
Janssen Pharmaceutica N.V., Belgium

Completed

GOLimumab and Methotrexate Versus Methotrexate in Very Early PsA (GOLMEPsA) (GOLMePsA)

Psoriatic Arthritis

United Kingdom
Holger Joswig
Innogenetics N.V., Belgium

Completed

The Pathogenesis of Terson Syndrome and the Role of CSF Tau / Amyloid-ß 40 and 42 in Patients With Aneurysmatic Subarachnoid Hemorrhage

Subarachnoid Hemorrhage | Terson Syndrome | CSF-proteines

Switzerland
Johnson & Johnson Pharmaceutical Research & Development...
Janssen Pharmaceutica N.V., Belgium

Completed

A Safety and Dose-finding Study of JNJ-26483327, a Drug in Development for Cancer, for Patients With Advanced and/or Refractory Solid Malignancies.

Pharmacokinetics | Advanced Malignancies | Solid Malignancies | Protein Kinase Inhibitors | Maximum Tolerated Dose | Antineoplastic Protocols | Clinical Trial, Phase 1
Maastricht University Medical Center
Scelta Mycofriends B.V.; CNC Grondstoffen B.V.

Recruiting

Agaricus Bisporus and Influenza Vaccination Response

Immune Response

Netherlands
Seaborough Life Science B.V.
University of Groningen; Chrono@Work B.V.

Not yet recruiting

PBM Effects on Health and Well-being in Humans

Sleep Deprivation | Circadian Rhythm Disorders
Janssen Vaccines & Prevention B.V.

Completed

A Study to Evaluate Different Dose Levels of Ad26.COV2.S in Healthy Adolescents From 12 to 17 Years Inclusive (HORIZON 2)

Coronavirus Disease-2019 (COVID-19) Prevention

Mexico, South Africa, Brazil, Argentina, India
Janssen Vaccines & Prevention B.V.

Terminated

A Study of Various Respiratory Syncytial Virus (RSV) Pre-Fusion (preF)-Based Vaccine Formulations in Adults Aged 60 Years and Older

Respiratory Syncytial Virus-associated Lower Respiratory Tract Disease Prevention

United States
Janssen Vaccines & Prevention B.V.

Completed

A Study of Ad26.COV2.S in Healthy Pregnant Participants (COVID-19) (HORIZON 1)

COVID-19 Prevention

United States, South Africa, Brazil
Wissenschaftliches Institut Bethanien e.V

Completed

Comparison of CPAP With SOMNOventCR in Patients With Underlying Heart Disease, Combined OSA and CSR (VCR)

Heart Diseases | Sleep Apnea, Obstructive | Sleep Apnea, Central
Wissenschaftliches Institut Bethanien e.V

Completed

Different Loop Gain Phenotypes in Patients With Chronic Systolic Heart Failure and Periodic Breathing

Periodic Breathing

Germany
Janssen Vaccines & Prevention B.V.

Completed

A Study Evaluating the Immunogenicity of Different Clinical Trial Materials of Ad26.RSV.preF- Based Vaccine in Adults Aged 60 - 75 Years Old

Respiratory Syncytial Virus Prevention

United States
Janssen Vaccines & Prevention B.V.

Completed

A Study of an Ad26.RSV.preF-based Vaccine and High-dose Seasonal Influenza Vaccine, With and Without Coadministration, in Adults Aged 65 Years and Older

Influenza, Human Prevention | Respiratory Syncytial Viruses Prevention

United States
Janssen Vaccines & Prevention B.V.

Completed

A Study of 2-dose Vaccine Regimen Using 3 Consecutive Lots of Ad26.ZEBOV and MVA-BN-Filo in Adult Participants

Ebola

United States
Janssen Vaccines & Prevention B.V.

Terminated

A Study to Assess the Efficacy of a Heterologous Prime/Boost Vaccine Regimen of Ad26.Mos4.HIV and Aluminum Phosphate-Adjuvanted Clade C gp140 in Preventing Human Immunodeficiency Virus (HIV) -1 Infection in Women in Sub-Saharan Africa

HIV-1

South Africa, Malawi, Mozambique, Zambia, Zimbabwe
Liquid I.V.
Lipscomb University

Completed

Efficacy of Different Oral Rehydration Solutions on the Hydration Status of Healthy Males

Fluid Retention | Beverage Hydration Index | Hydration Status

United States
Wissenschaftliches Institut Bethanien e.V

Completed

Epidemiological Analysis of Ambulant Patients in a COVID-19 Outpatient Clinic

COVID-19

Germany
Wissenschaftliches Institut Bethanien e.V

Completed

Epidemiological Multicohort Study of Latent COVID-19 Infections

COVID-19

Germany
L.V. Prasad Eye Institute

Completed

Ologen® Collagen Matrix in Patients With Primary Congenital Glaucoma Undergoing Trabeculectomy

Primary Congenital Glaucoma | Developmental Glaucoma | Infantile Glaucoma

India
Janssen Vaccines & Prevention B.V.

Completed

Safety and Efficacy Study of Vaccine Schedule With Ad26.Mos.HIV and MVA-Mosaic in Human Immunodeficiency Virus (HIV)-Infected Adults

Human Immunodeficiency Virus

Thailand
Wissenschaftliches Institut Bethanien e.V

Completed

The Debated Role of Sleep Studies in Patients Under Established Home Mechanical Ventilation

Chronic Obstructive Pulmonary Disease | Neuromuscular Diseases | Obesity Hypoventilation Syndrome | Restrictive Lung Disease | Hypoventilation Syndrome

Germany
Janssen Vaccines & Prevention B.V.

Completed

A Study to Evaluate the Safety and Immunogenicity of Seasonal Influenza Vaccine and an Adenovirus Serotype 26- Based Vaccine Encoding for the Respiratory Syncytial Virus Pre-fusion F Protein (Ad26.RSV.preF), With and Without Co-administration, in Adults Aged 60 Years and Older in Stable Health

Healthy

United States
Janssen Vaccines & Prevention B.V.

Completed

A Study to Assess the Safety, Reactogenicity and Immunogenicity of a Trivalent Inactivated Poliovirus Vaccine (IPV) Based on Sabin Strains Compared to Conventional Salk IPV in a 6, 10 and 14 Weeks of Age Immunization Schedule

Healthy

Philippines
Janssen Vaccines & Prevention B.V.

Completed

Safety, Tolerability and Immunogenicity Study of Different Vaccine Schedules With Ad26.Mos.HIV and Clade C Glycoprotein (gp)140 in Healthy Human Immunodeficiency Virus (HIV)-Uninfected Adults

Healthy

United States
Wissenschaftliches Institut Bethanien e.V

Completed

Inspiratory Muscle Training During Right-heart Catheterization

Respiratory Muscle Training | Right-heart Hemodynamics | Inspiratory Resistance

Germany
Wissenschaftliches Institut Bethanien e.V

Completed

Travelling in Patients With Sleep Related Breathing Disorders

Travel, Sleep Related Disorder
Medical Enterprises Europe B.V.

Withdrawn

SHTC - EUROPE-1 Synergo Hyperthermia-Chemotherapy by European Urologists' Research Operation Preserving Evolution Study I (SHTC-EUROPE-1)

Neoplasms | Urologic Neoplasms | Urogenital Neoplasms | Neoplasms by Site | Urologic Diseases | Urinary Bladder Diseases | Urinary Bladder Neoplasms
N.M. Wulffraat

Completed

Treatment of Steroid Resistant GVHD by Infusion MSC (MSCforGVHD)

Graft-versus-host-disease

Netherlands
Allergan S.A. DE C.V..

Completed

Comparison of Efficacy & Tolerability Between Ganfort vs Krytantek in Mexican Patients With Primary Open-Angle Glaucoma (POAG) or Ocular Hypertension (OHT)

Glaucoma Primary Open Angle

Mexico
Foerderinitiative Pharmazeutische Betreuung e.V.

Unknown

Pharmaceutical Care of Patients With Impaired Mobility in a Model-region of Decreasing Supply of Medical Services

Diabetes
Probiomed S.A. de C.V.

Unknown

TREatment of degeNerative and Neoplastic Diseases With Rituximab (TREND)

Diffuse Large B Cell Lymphoma

Mexico

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