Clinical Trials Sponsored by Alphacore Pharma, LLC

Total 331 results

Pfizer
Astellas Pharma Inc; Medivation LLC, a wholly owned subsidiary of Pfizer Inc.

Completed

A Phase 1 Study of MDV3100 in Patients With Castration-Resistant (Hormone-Refractory) Prostate Cancer

Prostate Cancer | Hormone Refractory Prostate Cancer

United States
Pfizer
Astellas Pharma Inc; Medivation LLC, a wholly owned subsidiary of Pfizer Inc.

Completed

Safety Study of Enzalutamide (MDV3100) in Patients With Incurable Breast Cancer

Breast Cancer

United States
Pfizer
Astellas Pharma Inc; Medivation LLC, a wholly owned subsidiary of Pfizer Inc.

Completed

Safety and Efficacy Study of MDV3100 in Patients With Castration-Resistant Prostate Cancer Who Have Been Previously Treated With Docetaxel-based Chemotherapy (AFFIRM)

Castration-Resistant Prostate Cancer

United States, Canada, France, Spain, United Kingdom, Australia, Poland, Germany, Austria, Belgium, Netherlands, Italy, Chile, South Africa, Argentina
Pfizer
Astellas Pharma Inc; Medivation LLC, a wholly owned subsidiary of Pfizer Inc.

Completed

Determine Effect of Enzalutamide (MDV3100) on the Androgen Signaling Pathway in Correlation With the Anti-tumor Effects of Enzalutamide

Metastatic Progressive Castration-resistant Prostate Cancer

United States
Fundacion SEIMC-GESIDA
Merck Sharp & Dohme LLC; Pfizer; Gilead Sciences; Astellas Pharma Inc

Completed

Prospective Population Study on Candidemia in Spain (CANDIPOP)

Fungemia

Spain
Ology Bioservices
Pharm-Olam, LLC; Chemical, Biological, Radiological, and Nuclear Medical

Withdrawn

Study of Adalimumab or Placebo in Patients With Mild to Moderate COVID-19 (COMBAAT) (COMBAAT)

Mild to Moderate COVID-19
Derm Research, PLLC
Bayer Healthcare Pharmaceuticals, Inc./Bayer Schering Pharma

Completed

Finacea 15% and Brimonidine 0.33% Gel in the Treatment of Rosacea - A Pilot Study

Acne Rosacea

United States
Jean-Luc Van Laethem
Roche Pharma AG

Unknown

Effect on Tumor Perfusion of a Chemotherapy Combining Gemcitabine and Vismodegib Before Surgery in Pancreatic Cancer (NEOPACHI-001)

Pancreatic Adenocarcinoma Resectable

Belgium
Mark Garzotto, MD
Merck Sharp & Dohme LLC; Astellas Pharma Inc

Recruiting

Neoadjuvant Pembrolizumab Plus Androgen Axis Blockade Prior to Prostatectomy for High Risk Localized Prostate Cancer

Prostate Cancer

United States
MEDA Pharma GmbH & Co. KG
ClinResearch, GmbH; Trio Clinical Research, LLC, Raleigh, USA; NuCara Pharmacy... and other collaborators

Completed

Relative Potency of Formoterol Novolizer® 12 µg Compared to Formoterol Aerolizer® 12 µg

Asthma

United States
The University of Texas Health Science Center,...
Midatech Pharma plc

Recruiting

Infusion of Panobinostat (MTX110) Into the Fourth Ventricle in Children and Adults With Recurrent Medulloblastoma

Medulloblastoma

United States
Cliniques universitaires Saint-Luc- Université...
Geistlich Pharma AG

Recruiting

GBR With L-PRF Bone Block in Early Healing Phase After Extraction (LPRF-GBR)

Alveolar Ridge Augmentation

Belgium
TcLand Expression S.A.
Premier Research Group plc; Theradis pharma; Medpharmgene, Inc.

Terminated

Validation Study of RA-INF-Dx, a Multigene Molecular Test Used to Predict Non-Response to INfliximab Therapy (PRINT)

Rheumatoid Arthritis

Canada, France, Hungary, Italy, Lithuania, Romania, Slovakia, Spain
Emory University
National Cancer Institute (NCI); Merck Sharp & Dohme LLC; Astellas Pharma Inc; Seagen...

Recruiting

Enfortumab Vedotin Plus Pembrolizumab for the Treatment of Locally Advanced or Metastatic Bladder Cancer of Variant Histology

Stage III Bladder Cancer AJCC v8 | Stage IV Bladder Cancer AJCC v8 | Bladder Adenocarcinoma | Bladder Squamous Cell Carcinoma | Metastatic Bladder Carcinoma | Urachal Adenocarcinoma | Locally Advanced Bladder Carcinoma | Malignant Renal Pelvis Neoplasm | Malignant Ureter Neoplasm | Malignant Urethral Neoplasm and other conditions

United States
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID); Exegi Pharma...

Completed

Effects of the Probiotic Visbiome Extra Strength on Gut Microbiome & Immune Activation Markers

HIV-1 Infection

United States, Puerto Rico
Memorial Sloan Kettering Cancer Center
Merck Sharp & Dohme LLC; Astellas Pharma US, Inc.; Seagen Inc.

Recruiting

Enfortumab Vedotin and Pembrolizumab in People With Bladder Cancer

Urothelial Carcinoma

United States
Faes Farma, S.A.
Merck Sharp & Dohme LLC; Allied Research International

Completed

Efficacy, Safety and PK of Once or Twice Daily Bilastine (10 or 20 mg) Compared With Placebo in the Symptomatic Treatment of SAR

Hypersensitivity | Allergic Conjunctivitis | Seasonal Allergic Rhinitis | Hay Fever

United States
Angela Kashuba, PharmD
Merck Sharp & Dohme LLC

Completed

Study to Characterize the Pharmacokinetics of Raltegravir in the Gastrointestinal (GI) Tract of Healthy Male Volunteers

Healthy Volunteer

United States
Biopharma Plasma LLC
Lviv National Medical University; Vinnitsa National Medical University

Completed

Intravenous Immunoglobulin (IVIG, Bioven) Efficacy Assess for COVID-19 / SARS-CoV-2 Severe Pneumonia Complex Treatment

Pneumonia | Covid19

Ukraine
Keio University
Merck Sharp & Dohme LLC; Ohara Pharmaceutical Co., Ltd.

Recruiting

Imatinib Mesylate in Combination With Pembrolizumab in Patients With Melanoma

Melanoma

Japan
City of Hope Medical Center
CSL Behring; Grifols Therapeutics LLC; Grifols Biologicals, LLC; Charta Foundation and other collaborators

Withdrawn

Study of First TIME Immunotolerance Induction in Severe Hemophilia A Patients With Inhibitor at High Risk of Failure: Comparison With FVIII Concentrates With or Without Von Willebrand Factor - RES.I.S.T. Naive (RESIST NAIVE)

Severe Hemophilia A
Albany College of Pharmacy and Health Sciences
Merck Sharp & Dohme LLC

Completed

Ertapenem Pharmacokinetics in Patients in Continuous Ambulatory Peritoneal Dialysis

End Stage Renal Disease | Continuous Ambulatory Peritoneal Dialysis

United States
City of Hope Medical Center
CSL Behring; Grifols Therapeutics LLC; Grifols Biologicals, LLC; Charta Foundation and other collaborators

Completed

Rescue Immunotolerance Study in Induction of Immune Tolerance (ITI)-Experienced Patients (RES.I.S.T. Experienced) (RESIST EXP)

Severe Hemophilia A

United States
Amit.Pai
Merck Sharp & Dohme LLC

Completed

Single Dose PK of IV Tedizolid Phosphate in Morbidly Obese and Non-Obese Adults

Obesity
R-Pharm International, LLC
Data Management 365; Federal State Budgetary Educational Institution for Higher... and other collaborators

Withdrawn

Efficacy and Safety Clinical Study of RPH-104 in Adult Onset Still's Disease (AOSD)

Adult-Onset Still's Disease | AOSD

Russian Federation
Sidney Kimmel Comprehensive Cancer Center at Johns...
Merck Sharp & Dohme LLC; Astellas Pharma Inc; Seagen Inc.

Not yet recruiting

Renal Retention in High Grade Upper Tract Urothelial Cancer

Bladder Cancer | Urothelial Carcinoma Bladder | High Grade Urothelial Carcinoma

United States
Asociacion para el Estudio del Higado
Merck Sharp & Dohme LLC

Unknown

Chronic Hepatitis C in Chronic Hemodialysis Recipients - An Observational Study ((CHINCHERO))

HCV Infection
Syneos Health
Merck Sharp & Dohme LLC; Sandoz; Teva Pharmaceuticals USA; Aurobindo Pharma Ltd; Zydus...

Terminated

The Ribavirin Pregnancy Registry (RPR)

Hepatitis C | Pregnancy Complications | Birth Defects

United States
Ludwig-Maximilians - University of Munich
Eli Lilly and Company; Sanofi; Novartis; AstraZeneca; Chugai Pharma USA; Janssen Diagnostics...

Completed

Simultaneous Study of Gemcitabine-Docetaxel Combination Adjuvant Treatment, as Well as Extended Bisphosphonate and Surveillance-Trial

Breast Neoplasms

Germany
ANRS, Emerging Infectious Diseases
Bristol-Myers Squibb; Merck Sharp & Dohme LLC; Gilead Sciences; Roche Pharma AG; Janssen-Cilag...

Active, not recruiting

Therapeutic Option for Hepatitis B and C: a French Cohort (HEPATHER)

Viral Hepatitis C | Viral Hepatitis B

France
Galmed Pharmaceuticals Ltd
Kramer Consulting, LLC; WCCT Global; Diamond Pharma Services Regulatory Affairs... and other collaborators

Completed

Pharmacokinetics of Single and Multiple Escalating Doses of Aramchol Administered Under Fed Conditions in Healthy Chinese Volunteers

Healthy Volunteers

United States
R-Pharm
Covance; Data Matrix Solutions; ZAO Unimed Laboratories; Pharmaceutical Analytics... and other collaborators

Terminated

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Evaluation of RPH-104 Administered at Different Doses to Patients With Acute Gout Attack

Gout Attack

Russian Federation
Dr. August Wolff GmbH & Co. KG Arzneimittel
Pharmaxi LLC; Labor Dr. Fenner und Kollegen

Recruiting

Clinical Trial of a Mouth and Throat Rinse for the Treatment of Acute Sore Throat

Upper Respiratory Infection | Sore-throat

Ukraine
University of Medicine and Pharmacy at Ho Chi Minh...
Merck Sharp & Dohme LLC

Unknown

Deep Neuromuscular Block and Sugammadex Versus Standard of Care on Quality of Recovery in Patient Undergo Elective Laparoscopic Cholecystectomy

Neuromuscular Block

Vietnam
MEDA Pharma GmbH & Co. KG
ICON plc; Clinipace Worldwide; Trium Analysis Online GmbH

Terminated

Tepilta® Versus Oxetacaine, Antacids and Placebo

Radiation-induced Oesophagitis

Germany, Austria
Asociacion para el Estudio de las Enfermedades...
Merck Sharp & Dohme LLC

Completed

Bitherapy With the Combination of Raltegravir and Darunavir (BIRDi) (BIRDi)

HIV/AIDS | Comorbidities

Spain
UNICANCER
Bristol-Myers Squibb; Sanofi; Merck Sharp & Dohme LLC; Pfizer; Roche Pharma AG; Ast... and other collaborators

Recruiting

Evolution of the Therapeutic Care in Lung Cancer in France Since 2015 (ESME LC)

Lung Cancer

France
Spondyloarthritis Research and Treatment Network
Eli Lilly and Company; UCB Pharma; Pfizer; AbbVie; Janssen Scientific Affairs, LLC; Novartis Pharmaceuticals and other collaborators

Completed

CLassification of Axial SpondyloarthritiS Inception Cohort (CLASSIC)

Spondyloarthritis

United States, Canada, Mexico
Hong Kong Nasopharyngeal Cancer Study Group Limited
Sanofi; The University of Hong Kong; Merck Sharp & Dohme LLC; Roche Pharma AG

Completed

Study to Evaluate Induction Chemotherapy Using Docetaxel, Cisplatin and Fluorouracil in Concurrence With Intensity-modulated Radiotherapy for Local Recurrent Nasopharyngeal Carcinoma (NPC)

Nasopharyngeal Carcinoma

China
Intergroupe Francophone du Myelome
Bristol-Myers Squibb; Takeda; University Hospital, Grenoble; Nantes University... and other collaborators

Terminated

IPD in RRMM Characterized With Genomic Abnormalities of Adverse Prognostic (IFM2014-01)

Multiple Myeloma | Genetic Condition | Relapsed and Refractory Multiple Myeloma

France
SOLTI Breast Cancer Research Group
Merck Sharp & Dohme LLC; Pfizer; AstraZeneca; Astellas Pharma Inc; Advanced Accelerator... and other collaborators

Recruiting

Feasibility and Impact of Liquid Biopsy Genomic Profiling on Treatment Patients With Metastatic Prostate Cancer in Spain (SOLTI-2102) (HOPE-PROSTATE)

Metastatic Prostate Cancer

Spain
Camino Pharma, LLC
National Institute on Drug Abuse (NIDA); University of California, San Diego; Sanford Burnham Prebys Medical Discovery Institute

Completed

A First-in-Human Study of SBP-9330 in Healthy Subjects

Smoking Cessation

United States
University of Pittsburgh
Merck Sharp & Dohme LLC; RTI International; Rite Aid Corp.; Pharmacy Quality Alliance

Completed

Effect of Community Pharmacist Intervention on Adherence to Long-Term Medications (ECO-PHIL)

Medication Adherence

United States
University of Florida
National Institute on Alcohol Abuse and Alcoholism (NIAAA); University of Miami and other collaborators

Recruiting

The Path Study: Cognitive and Inflammation Targeted Gut-brain Interventions in Alcohol; Probiotics, Alcohol, Transcutaneous Vagus Nerve Stimulation, and HIV Study

Cognition | Gut Microbiome

United States
Aphaia Pharma US LLC
NovaClin Medical Research Center S.R.L; ACC GmbH Analytical Clinical Concepts; SC Bioclinica... and other collaborators

Completed

Pharmacodynamics and Pharmacokinetics of Different Glucose Bead Formulations in Obese Healthy Subjects

Obese

Romania
Kyoto University Hospital
Merck Sharp & Dohme LLC; Astellas Pharma Inc; University of Tsukuba; Kobe City... and other collaborators

Recruiting

Pembrolizumab and EV With Radiation Therapy for MIBC Patients (PEVRAD)

Bladder Cancer

Japan
N-Gene Research Laboratories, Inc.
Thermo Fisher Scientific, Inc; Integrium; Msource Medical Development GmbH; Kinexum... and other collaborators

Terminated

Safety and Efficacy of BGP-15 in Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus

United States, Germany, Hungary
Kirby Institute
Bristol-Myers Squibb; GlaxoSmithKline; Merck Sharp & Dohme LLC; Roche Pharma AG; Boehringer... and other collaborators

Completed

Can Resistance Enhance Selection of Treatment? (CREST)

HIV Infection

Australia
University of British Columbia
GlaxoSmithKline; Merck Sharp & Dohme LLC; Pfizer; Roche Pharma AG; AstraZeneca; Janssen... and other collaborators

Completed

The Implementation of Pharmacogenomics Into Primary Care in British Columbia (IPPC)

Pharmacogenetics
Fundacion para la Investigacion Biomedica del Hospital...
Merck Sharp & Dohme LLC

Completed

ARTiBIOME: Observational Study on the Effect of HIV and ART on Gut Microbiome

HIV Infections

Spain

Clinical Trials Sponsored by Alphacore Pharma, LLC

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Gabon

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations