Clinical Trials Sponsored by Cancer Advances Inc.

Total 4497 results

Therapeutic Advances in Childhood Leukemia Consortium
Genzyme, a Sanofi Company

Terminated

Clofarabine With Cytarabine for Patients With Minimal Residual Disease Positive Leukemia

Minimal Residual Disease | Leukemia, Lymphoblastic, Acute | Leukemia, Myelogenous, Acute

United States
Gustave Roussy, Cancer Campus, Grand Paris
National Cancer Institute, France; Advanced Accelerator Applications

Recruiting

Antitumor Efficacy of Peptide Receptor Radionuclide Therapy With 177Lutetium -Octreotate Randomized vs Sunitinib in Unresectable Progressive Well-differentiated Neuroendocrine Pancreatic Tumor: First Randomized Phase II (OCCLURANDOM)

Pancreatic Neuroendocrine Carcinoma

France
Therapeutic Advances in Childhood Leukemia Consortium
Genzyme, a Sanofi Company

Completed

Clofarabine and Low Dose Total Body Irradiation as a Preparative Regimen for Stem Cell Transplant in Leukemia.

Acute Myeloid Leukemia | Leukemia Lymphoblastic, Acute | Neoplasm Recurrent

United States
Elucida Oncology
Therapeutic Advances in Childhood Leukemia and Lymphoma (TACL)

Withdrawn

ELU001 in Pediatric Subjects Who Have Relapsed and/or Refractory CBFA2T3-GLIS2-positive AML (Pediatric AML)

Acute Myeloid Leukemia | AML, Childhood | Relapsed Pediatric AML | Refractory Pediatric AML
M.D. Anderson Cancer Center
Genentech, Inc.; Millennium Pharmaceuticals, Inc.

Withdrawn

Phase I-II for Patients With Recurrent or Refractory Non-small Cell Lung Cancer (NSCLC)

Lung Cancer
Myant Medical Corp.
Partners in Advanced Cardiac Evaluation

Completed

Holter Versus Skiin Garments

Cardiac Arrhythmia

Canada
OncoC4, Inc.
Avance Clinical; OncoC4 AU Pty Ltd

Recruiting

Safety, PK and Efficacy of AI-061 in Advanced Solid Tumors (PRESERVE-009)

Melanoma | Renal Cell Carcinoma | Cervical Cancer | Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Esophageal Cancer | Fallopian Tube Cancer | Non Small Cell Lung Cancer | Bile Duct Cancer | Bladder Cancer | Endometrial Cancer | Head and Neck Squamous Cell Carcinoma | Anal Cancer | Primary Peritoneal... and other conditions

Australia
UNC Lineberger Comprehensive Cancer Center
Eli Lilly and Company; Genentech, Inc.

Completed

Combination Chemotherapy, Bev, RT, and Erlotinib in Treating Patients With Stage III Non-Small Cell Lung Cancer

Lung Cancer

United States
UNC Lineberger Comprehensive Cancer Center
GlaxoSmithKline; Genentech, Inc.; Susan G. Komen Breast Cancer Foundation

Completed

Defining the HER2 Positive (+) Breast Cancer Kinome Response to Trastuzumab, Pertuzumab, Combination Trastuzumab +Pertuzumab, or Combination Trastuzumab + Lapatinib

Breast Neoplasms

United States
Memorial Sloan Kettering Cancer Center
American Cancer Society, Inc.

Active, not recruiting

Collection Of Tissue, Blood, and Other Specimens From Patients With Head and Neck Tumors To Study the Causes, Diagnosis, Prevention and Treatment of Cancers

Head and Neck Cancers

United States
Vestan, Inc.
M.D. Anderson Cancer Center; Huntsman Cancer Institute

Unknown

VST-1001 (Dilute Fluorescein) for Lymphatic Mapping & Localization of Lymph Nodes in Patients With Breast Cancer

Breast Cancer

United States
Memorial Sloan Kettering Cancer Center
American Cancer Society, Inc.

Completed

Adherence to Intensive Surveillance for Hereditary Breast Cancer

Breast Cancer

United States
Memorial Sloan Kettering Cancer Center
American Cancer Society, Inc.

Completed

Care For The Cancer Caregiver: A Meaning-Based Workshop To Help Manage Caregiver Burden

Caregivers

United States
Biomedical Advanced Research and Development Authority
Rho Federal Systems Division, Inc.; Allucent

Not yet recruiting

Sublingual Atropine Bioequivalence by Route of Administration (SABER) (SABER)

Atropine Bioequivalence

United States
Helio Genomics
Helio Health Inc., Irvine, CA; Laboratory for Advanced Medicine, Guangzhou

Completed

Performance Evaluation (Sensitivity/Specificity) of HelioLiver Test for Detection of HCC (ENCORE)

Hepatocellular Carcinoma by AJCC Stage

China
Perseverance Research Center, LLC
Cerulean Advanced Fitness and Wellness

Completed

Specialized Food Plan Based on Individual Physiological Comprehensive Body Assessments Accompanied With Cellular Repair Therapy to Decrease Inflammation Cognitively Impaired Patients

Alzheimer Disease | Mild Cognitive Impairment

United States
University of Texas Southwestern Medical Center
Advanced Vision Research

Completed

A Placebo Controlled Double Masked Clinical Assessment Study of Essential Fatty Acid Supplement and Its Effect on Patients With Apparent Aqueous Deficient Dry Eye Syndrome

Dry Eye Syndrome

United States
Memorial Sloan Kettering Cancer Center
American Cancer Society, Inc.

Active, not recruiting

Determinants of Bladder Cancer Recurrence Study (The DETER Study)

Bladder Cancer

United States
Memorial Sloan Kettering Cancer Center
American Cancer Society, Inc.

Active, not recruiting

Group Interventions for Breast Cancer Survivors

Breast Cancer Survivor

United States
UNC Lineberger Comprehensive Cancer Center
Merck Sharp & Dohme LLC; Millennium Pharmaceuticals, Inc.; Ortho Biotech, Inc.

Terminated

Vorinostat, Bortezomib, and Doxorubicin Hydrochloride Liposome in Treating Patients With Relapsed or Refractory Multiple Myeloma

Multiple Myeloma and Plasma Cell Neoplasm

United States
Shape Divine Center SRL
SmartepigenetX SRL; Advanced Nutrigenomics LLC

Recruiting

Precision Nutrition (NP)

Nutrient Deficiency

Romania
Radboud University Medical Center
ABX advanced biochemical compounds GmbH

Active, not recruiting

18F-PSMA-1007 PET Imaging to Detect Primary Prostate Cancer (PICture)

Prostate Cancer

Netherlands
Advanced Cooling Therapy, Inc., d/b/a Attune Medical
University of Iowa

Completed

Evaluating Active Esophageal Cooling During Cardiac Ablation Procedures

Atrial Fibrillation

United States
M.D. Anderson Cancer Center
Novartis; Puma Biotechnology, Inc.; Celcuity Inc

Recruiting

Neratinib and Capmatinib Combination (Phase Ib/II) in Metastatic Breast Cancer and Inflammatory Breast Cancer Patients With Abnormal HER-family and c-Met Pathway Activity as Measured by the CELsignia Signaling Analysis Test

Breast Cancer | Metastatic Breast Cancer

United States
Ohio State University Comprehensive Cancer Center
American Cancer Society, Inc.; Lance Armstrong Foundation

Completed

Cognitive-Behavioral Intervention for Worry, Uncertainty, and Insomnia for Cancer Survivors (FOCUS)

Depression | Pain | Leukemia | Fatigue | Multiple Myeloma | Insomnia | Pancreatic Cancer | Esophageal Cancer | Lung Cancer | Glioblastoma Multiforme | Sleep Disorders | Uncertainty | Ovarian Neoplasm | Anxiety Disorder | Psychological Intervention | Relapsed Lymphoma | Worry | Cognitive-behavioral Therapy | Stage III or IV Cervical... and other conditions

United States
Keller Army Community Hospital
Telemedicine & Advanced Technology Research Center

Unknown

Gait Retraining Enhances Athletes' Technique (GREAT)

Knee Osteoarthritis | Anterior Cruciate Ligament Injury

United States
Advanced Cooling Therapy, Inc., d/b/a Attune Medical
Thomas Jefferson University

Terminated

Intraoperative Warming During Major Surgical Procedures Using the Esophageal Temperature Management System

Surgery | Hypothermia | Hypothermia Following Anesthesia

United States
Vanderbilt-Ingram Cancer Center
Astex Pharmaceuticals, Inc.; Forma Therapeutics, Inc.

Withdrawn

ASTX727 and FT-2102 in Treating IDH1-Mutated Recurrent/Refractory Myelodysplastic Syndrome or Acute Myeloid Leukemia

Acute Myeloid Leukemia | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Recurrent Myelodysplastic Syndrome | Refractory Acute Myeloid Leukemia | Refractory Myelodysplastic Syndrome
M.D. Anderson Cancer Center
Kura Oncology, Inc.

Not yet recruiting

A Phase I Study Investigating the Combination of the Ziftomenib, Venetoclax and Azacitidine in Pediatric Relapsed and Refractory Acute Leukemias

Refractory Acute Leukemia | Pediatric Relapsed

United States
Memorial Sloan Kettering Cancer Center
Seagen Inc.

Recruiting

A Study of BV-AVD in People With Bulky Hodgkin Lymphoma

Hodgkin Lymphoma

United States
Memorial Sloan Kettering Cancer Center
Genentech, Inc.

Recruiting

A Study of Glofitamab and Lenalidomide in People With Mantle Cell Lymphoma

Mantle Cell Lymphoma | MCL

United States
M.D. Anderson Cancer Center
Astex Pharmaceuticals, Inc.

Recruiting

A Phase Ia/Ib Open-label, Multiple Dose, Study to Determine the Recommended Dose, Evaluate PKs, PDs, Safety, and Activity of Venetoclax in Combination With Oral Decitabine/Cedazuridine (ASTX727) in Pediatric Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia

United States
M.D. Anderson Cancer Center
Mirati Therapeutics Inc.

Recruiting

Phase Ib Trial of the KRAS G12C Inhibitor Adagrasib (MRTX849) in Combination With the PARP Inhibitor Olaparib in Patients With KRAS G12C Mutated Advanced Solid Tumors, With a Focus on Gynecological, Breast, Pancreatic and KEAP1 Mutated Non-small Cell Lung Cancers

Advanced Solid Tumor | Non-small Cell Lung Cancers

United States
Shenzhen TargetRx, Inc.
M.D. Anderson Cancer Center

Not yet recruiting

TGRX-678 US Phase I for Subjects With Refractory or Advanced Chronic Myelogenous Leukemia

Chronic Myelogenous Leukemia

United States
M.D. Anderson Cancer Center
AVEO Pharmaceuticals, Inc.

Recruiting

Phase 2 Study of Combination Tivozanib and Nivolumab in Advanced Non-Clear Cell Renal Cell Carcinoma

Renal Cell Carcinoma

United States
Memorial Sloan Kettering Cancer Center
Verastem, Inc.

Recruiting

A Study of Avutometinib and Defactinib in People With Thyroid Cancer

Thyroid Cancer

United States
Memorial Sloan Kettering Cancer Center
Seagen Inc.

Recruiting

A Study of Tucatinib Given Before Surgery to People With HER2+ Cancers That Have Spread to the Brain

Metastatic Breast Cancer

United States
Memorial Sloan Kettering Cancer Center
Verastem, Inc.

Recruiting

A Study of Avutometinib (VS-6766) and Defactinib in People With Mesonephric Gynecologic Cancer

Mesonephric Gynecologic Cancer

United States
M.D. Anderson Cancer Center
Tvardi Therapeutics, Inc

Not yet recruiting

Phase I/II Open Label Study Evaluating the Safety and Efficacy of Combining STAT3 Inhibition (TTI-101) With Anti-PD-1 Therapy (Pembrolizumab) in Patients With Recurrent or Metastatic (RM) Head and Neck Squamous Cell Carcinoma (HNSCC)

Head and Neck Squamous Cell Carcinoma
M.D. Anderson Cancer Center
Mirati Therapeutics Inc.

Recruiting

Phase Ib Trial of the KRASG12C Inhibitor Adagrasib (MRTX849) in KRAS G12C Mutant Metastatic Pancreatic Cancer Patients

Metastatic Pancreatic Cancer

United States
Memorial Sloan Kettering Cancer Center
SynDevRx, Inc.

Recruiting

A Study of SDX-7320 in Combination With Eribulin for People With Breast Cancer

Breast Cancer | Metastatic Triple-Negative Breast Cancer

United States
Memorial Sloan Kettering Cancer Center
Genentech, Inc.

Recruiting

A Study of Venetoclax in Combination With Chemotherapy to Treat Newly Diagnosed Acute Lymphoblastic Leukemia (ALL)

Acute Lymphoblastic Leukemia

United States
Jonsson Comprehensive Cancer Center
Novartis; Seagen Inc.

Recruiting

Ribociclib, Tucatinib, and Trastuzumab for the Treatment of HER2 Positive Breast Cancer

Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC v8 | Anatomic Stage IIIC Breast Cancer AJCC... and other conditions

United States
Jonsson Comprehensive Cancer Center
Kate Farms Inc

Recruiting

Pea Protein Oral Nutrition Supplement for the Reduction of Gastrostomy Tube Placement Rate in Patients With Locally Advanced Head and Neck Cancer Undergoing Chemoradiation Therapy

Locally Advanced Head and Neck Carcinoma

United States
Fred Hutchinson Cancer Center
Lonza Walkersville, Inc.

Recruiting

Mesothelin-Specific T-Cells (FH-TCR-Tᴍsʟɴ) for the Treatment of Metastatic Pancreatic Ductal Adenocarcinoma

Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Ductal Adenocarcinoma

United States
Preferred Medicine, Inc
M.D. Anderson Cancer Center

Recruiting

Droplet-BC Screening Test for the Detection of Breast Cancer, the DROPLET-BC Study

Breast Carcinoma

United States
Jonsson Comprehensive Cancer Center
eHealth International, INC.

Recruiting

A Study to See if an iPhone Weight Management App Can Help Promote Weight Loss in Adolescents and Young Adults After a Stem Cell Transplant

Obesity | Malignant Neoplasm

United States
Cyclacel Pharmaceuticals, Inc.
M.D. Anderson Cancer Center

Recruiting

A Phase I Study of CYC140, a PLK-1 Inhibitor, in Advanced Leukemias or MDS

Myelodysplastic Syndromes | AML, Adult | ALL, Adult | CLL, Refractory | CML, Refractory

United States
Memorial Sloan Kettering Cancer Center
Seagen Inc.

Recruiting

Dosing of Brentuximab Vedotin for Mycosis Fungoides, Sezary Syndrome Patients

Mycosis Fungoides | Sezary Syndrome | Lymphomatoid Papulosis

United States
Memorial Sloan Kettering Cancer Center
Genentech, Inc.

Recruiting

Trial of Ado-Trastuzumab Emtansine for Patients With HER2 Amplified or Mutant Cancers

Lung Cancer | Bladder Cancer | Solid Tumor Cancers | Urinary Tract Cancers

United States

Clinical Trials Sponsored by Cancer Advances Inc.

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