Clinical Trials Sponsored by Cryotherapeutics SA

Total 1019 results

Debiopharm International SA

Recruiting

Study to Assess Safety, Tolerability and Efficacy of Afabicin in The Treatment of Participants With Bone or Joint Infection Due to Staphylococcus

Bone or Joint Infection

United States, Ukraine, Argentina, South Africa, Georgia
Celyad Oncology SA

Recruiting

alloSHRINK - Standard cHemotherapy Regimen and Immunotherapy With Allogeneic NKG2D-based CYAD-101 Chimeric Antigen Receptor T-cells (alloSHRINK)

Unresectable Metastatic Colorectal Cancer

Belgium, United States
Debiopharm International SA

Active, not recruiting

A Study to Assess the Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Debio 4126 in Participants With Acromegaly or Functioning Gastroenteropancreatic Neuroendocrine Tumors (GEP-NETs) (OXTEND-01)

Acromegaly | GEP-NET

United Kingdom, France, Spain, Italy, Poland, Denmark, Germany, Israel
Medacta International SA

Active, not recruiting

Medacta NextAR TKA Pivotal Trial

Musculoskeletal Diseases

Switzerland
Medacta International SA

Active, not recruiting

The Medacta International AMIStem-P Post-Marketing Surveillance Study

Arthrosis | Congenital Hip Dysplasia | Traumatic Arthritis | Rheumatoid Polyarthritis | Avascular Necrosis of the Femoral Head

France
Helsinn Healthcare SA

Active, not recruiting

Oral Akynzeo® vs Standard of Care in Preventing CINV in High-risk MEC Patients (MyRisk) (CINV)

Chemotherapy-induced Nausea and Vomiting

Spain, Germany, Switzerland, China, Czechia, United Kingdom, Greece
AB Biotics, SA

Completed

Trial to Evaluate Efficacy of Pharmacogenetic Information Obtained With NEUROPHARMAGEN in Treatment of MDD Patients

Depressive Disorder, Major

Spain
Polares Medical SA

Terminated

Early Feasibility Study of the PLAR Implant and Delivery System to Treat Degenerative Mitral Regurgitation (EXPLORE DMR)

Degenerative Mitral Valve Disease

United States
Medacta International SA

Active, not recruiting

Bone Fixation of Mpact Double Mobility Cup

Total Hip Replacement

France
Lymphatica Medtech SA

Terminated

LymphoPilot Test for Limb Lymphedema

Lymphedema of Upper Limb | Lymphedema, Secondary | Lymphedema, Lower Limb | Lymphedema of Leg | Lymphedema Arm

Switzerland
Celyad Oncology SA

Active, not recruiting

Safety, Activity and Cell Kinetics of CYAD-211 in Patients With Relapsed or Refractory Multiple Myeloma (IMMUNICY-1)

Relapse/Refractory Multiple Myeloma

Belgium, United States
Abionic SA
Avania

Completed

abioSCOPE PSP Reference Range Study; Extension of AB-PSP-003 (AB-PSP-007)

Sepsis

United States
Debiopharm International SA

Completed

Study to Assess Safety and Efficacy of the Second Mitochondrial-derived Activator of Caspases (SMAC) Mimetic Debio 1143 (SMARTPLUS-106)

Solid Tumor

United States, Spain, France
Contrad Swiss SA

Completed

Evaluation of the Effect of the AI500™ SINGLE-DOSE GEL Medical Device in Patients With Reduced Knee Function

Knee Osteoarthritis | Knee Injuries | Pain, Acute | Knee Arthritis | Pain, Chronic | Knee Pain Swelling

Italy
Rhizen Pharmaceuticals SA

Completed

Efficacy and Safety of Tenalisib (RP6530), a PI3K δ/γ and SIK3 Inhibitor, in Patients With Locally Advanced or Metastatic Breast Cancer

Metastatic Breast Cancer | Locally Advanced Breast Cancer

Georgia
Medacta International SA

Active, not recruiting

EBRA Study AMISTEM-C FR

Total Hip Arthroplasty

France
Sword Health, SA

Completed

Digital Home-based Rehabilitation for Musculoskeletal Disorders

Musculoskeletal Diseases

United States
Miracor Medical SA

Completed

Pressure-controlled Intermittent Coronary Sinus Occlusion (PiCSO) in Acute Myocardial Infarction (PiCSO-AMI-I)

STEMI | Anterior MI

United Kingdom, Denmark, Latvia, France, Germany, Switzerland
Quantum Genomics SA

Completed

Firibastat or Ramipril After Acute Myocardial Infarction for Prevention of Left Ventricular Dysfunction (QUORUM)

Myocardial Infarction

Poland, Germany, France, Hungary, Slovakia, Spain, United Kingdom
Pixium Vision SA

Active, not recruiting

Restoration of Central Vision With the PRIMA System in Patients With Atrophic AMD (PRIMAvera)

Geographic Atrophy

Germany, France, Italy, Netherlands, Spain, United Kingdom
Biosensors Europe SA

Completed

Rise Semi Compliant Balloon Study in Patient With CAD

Coronary Artery Disease

Switzerland
Rhizen Pharmaceuticals SA

Withdrawn

Study to Evaluate the Safety, Pharmacokinetics and Clinical Activity of RP7214 in Combination With Azacitidine in Patients With Myelodysplastic Syndrome, Chronic Myelomonocytic Leukemia and Acute Myeloid Leukemia

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Chronic Myelomonocytic Leukemia
Rhizen Pharmaceuticals SA

Withdrawn

Study to Evaluate the Efficacy and Safety of Tenalisib, Given With CHOP Therapy for Front Line Treatment in Patients With PTCL

Peripheral T Cell Lymphoma

United States
Biosensors Europe SA

Active, not recruiting

Biolimus A9™ (BA9™) Drug Coated Balloon (DCB) Study (REFORM)

Coronary Artery Disease | In-Stent Restenosis

Spain, Ireland, United Kingdom, Italy, Germany
Debiopharm International SA

Completed

Debio 1143-201 Dose-finding and Efficacy Phase I/II Trial

Squamous Cell Carcinoma of the Head and Neck

France, Switzerland
Debiopharm International SA

Completed

A Study to Evaluate the Absorption, Metabolism, and Excretion and Absolute Bioavailability of Xevinapant in Healthy Male Participants

Healthy Volunteers

United Kingdom
Chiesi SA/NV

Terminated

Study in COPD Patients Evaluating the Quality of Life (TRISNOOZE) (TRISNOOZE)

Chronic Obstructive Pulmonary Disease

Belgium
Chiesi SA/NV

Completed

Fixed Dose Triple Therapy in Severe Chronic Obstructive Pulmonary Disease in a Real World Setting (TRIVOLVE)

Chronic Obstructive Pulmonary Disease

Belgium
Chiesi SA/NV

Enrolling by invitation

Observational Study to Assess the Quality of Life in Nephropathic Cystinosis Patients (PROREAL)

Nephropathic Cystinosis

Belgium
Rhizen Pharmaceuticals SA

Completed

Efficacy and Safety Study of Tenalisib (RP6530), a Novel PI3K δ/γ Dual Inhibitor in Patients With Relapsed/Refractory Indolent Non-Hodgkin's Lymphoma (iNHL)

Non Hodgkin Lymphoma

United States, Australia
Helsinn Healthcare SA

Completed

Safety and Efficacy Study of Pracinostat With Azacitadine in Elderly Patients With Newly Diagnosed Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia

United States
Helsinn Healthcare SA

Completed

PK/PD Study of Netupitant and Palonosetron in Pediatric Patients for Prevention of Chemotherapy-induced Nausea and Vomiting (CINV)

Chemotherapy-induced Nausea and Vomiting (CINV)

United States, Russian Federation, Serbia, Ukraine
MedDay Pharmaceuticals SA

Completed

SERENDEM : MD1003 in Patients Suffering From Demyelinating Neuropathies, an Open Label Pilot Study

Charcot-Marie-Tooth Disease | Peripheral Neuropathy | Chronic Inflammatory Demyelinating Polyneuropathy | Charcot-Marie-Tooth Disease Type 1A | Charcot-Marie-Tooth Disease, Type 1B | Anti-MAG Neuropathy

France
Debiopharm International SA

Terminated

Debio 1347-101 Phase I Trial in Advanced Solid Tumours With Fibroblast Growth Factor Receptor (FGFR) Alterations

Solid Tumours

Korea, Republic of, United States, Taiwan, Spain, Singapore
Regen Lab SA

Unknown

Clinical Investigation to Compare the Safety and Efficacy of Cellular Matrix to Those of Ostenil® Plus and to Those of PRP Only

Knee Osteoarthritis
Biosensors Europe SA

Unknown

BioFreedom QCA Study in CAD Patients (BioFreedomQCA)

Myocardial Infarction | Coronary Artery Disease | Cardiac Death

Spain, Denmark
Rhizen Pharmaceuticals SA

Terminated

Safety, Tolerability and Pharmacokinetics of Oral Doses of RP3128 of Rhizen Pharmaceuticals

Asthma | Healthy Volunteers

Canada
Celyad Oncology SA

Unknown

A Dose Escalation Phase I Study to Assess the Safety and Clinical Activity of Multiple Cancer Indications (THINK)

Acute Myeloid Leukemia/Myelodysplastic Syndrome | Multiple Myeloma (MM)

United States, Belgium
Legacy Healthcare SA

Completed

Efficacy, Safety and Tolerability of CG428 Cutaneous Solution on Chemotherapy Induced Alopecia; Controlled Study (ELAN) (ELAN)

Alopecia

Switzerland
Quantum Genomics SA

Terminated

QUantum Genomics Incremental Dosing in Heart Failure - QUID-HF (QUID-HF)

Heart Failure

France, Germany, Netherlands, United Kingdom, Hungary, Norway, Czechia, Poland
AB Biotics, SA

Completed

A Trial to Evaluate the Efficacy of AB-Life Probiotic Product on LDL-Cholesterol Reduction in Moderate Hypercholesterolemia

Moderate Hypercholesterolemia

France
Graftys SA
Clinfile

Unknown

Calcium Phosphate Cement Registry (CPC Registry) (CPC)

Bone Disease | Fracture Bone | Bone Cyst

France, Germany, Italy, Martinique, Switzerland
Debiopharm International SA

Completed

Drug Penetration Into Bone After Repeated Oral Administration of Debio 1450 to Patients Undergoing Hip Replacement Surgery

Bone Diseases, Infectious

United States
Debiopharm International SA

Completed

Efficacy, Safety, and Pharmacokinetics (PK) of Triptorelin 6-month Formulation in Patients With Central Precocious Puberty

Central Precocious Puberty

United States, Chile, Mexico
Aleva Neurotherapeutics SA

Terminated

Evaluation of Directional Recording and Stimulation Using spiderSTN

Parkinson's Disease | Essential Tremor

Switzerland
MedDay Pharmaceuticals SA

Unknown

Effect of MD1003 in Chronic Visual Loss Related to Optic Neuritis in Multiple Sclerosis (MS-ON)

Multiple Sclerosis

United Kingdom, France
MedDay Pharmaceuticals SA

Unknown

Effect of MD1003 in Spinal Progressive Multiple Sclerosis (MS-SPI)

Multiple Sclerosis

France
Helsinn Healthcare SA

Completed

Evaluate the Effects of Itraconazole and Ciprofloxacin on Single-Dose PK of Pracinostat in Healthy Nonsmoking Subjects

Healthy Volunteers | Non-smokers

United States
Debiopharm International SA

Completed

Efficacy and Safety of Alisporivir Triple Therapy in Chronic Hepatitis C Genotype 1 Treatment-naïve Participants

Hepatitis C

United States, Romania, Belgium, Germany, Hungary, Taiwan, Spain, Italy, Australia, France, Hong Kong, Thailand, Korea, Republic of, United Kingdom, Argentina, Russian Federation, Canada, Poland, Puerto Rico, Vietnam, Mexico
Debiopharm International SA

Completed

Long Term Follow-up Study to Assess Durability of Sustained Virologic Response in Alisporivir-treated Hepatitis C Patients

Hepatitis C

Romania, Italy, Belgium, Germany, Hungary, Taiwan, Spain, Australia, Hong Kong, Thailand, France, United States, United Kingdom, Turkey, Argentina, Russian Federation, India, Korea, Republic of, Vietnam, Poland, Mexico, Canada

Clinical Trials Sponsored by Cryotherapeutics SA

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