Clinical Trials Sponsored by Medcare Plc

Total 11619 results

GlaxoSmithKline
ICON plc

Completed

FF/UMEC/VI Inhaler: Qualitative Analysis and Subject Preference Survey

Pulmonary Disease, Chronic Obstructive

United Kingdom
4D pharma plc

Completed

Study of Bacteroides Thetaiotaomicron in Young People Aged 16 to 18 Years With Stable Crohn's Disease

Crohn's Disease

United Kingdom
Gedeon Richter Plc.

Completed

Study to Compare the Pharmacokinetics and Pharmacodynamics of 6 mg RGB-02 to 6 mg Neulasta

Bioequivalence

United Kingdom
Mallinckrodt
ICON plc

Completed

Safety and Efficacy of Extracorporeal Photoimmune Therapy With UVADEX for the Treatment of Crohn's Disease

Crohn's Disease

Belgium, Germany, United States, Austria
Verona Pharma plc

Completed

The Effects of RPL554 on Top of Standard COPD Reliever Medications

Chronic Obstructive Pulmonary Disease

United Kingdom
Imperial Brands PLC

Completed

A Bioavailability Study of Nicotine Delivered by an Electronic Vapour Product

Healthy Volunteers

United Kingdom
Gedeon Richter Plc.

Completed

Cariprazine: Comparison of Slow- and Immediate-release Forms

Pharmacokinetic Profile

United Kingdom
Gedeon Richter Plc.

Unknown

Comparative Pharmacokinetic Trial of RGB-03 and MabThera

Rheumatoid Arthritis
Coherus Biosciences, Inc.
Shanghai Junshi Bioscience Co., Ltd.; Medpace, Inc.

Active, not recruiting

Study to Evaluate Safety and PK of CHS-006 in Combination With Toripalimab in Patients With Advanced Solid Tumors

Hepatocellular Carcinoma | Non-Small Cell Lung Cancer | Advanced Solid Tumor

United States
Theratechnologies
Vanderbilt University Medical Center; Medpace, Inc.; Dacima Consulting; Echosens

Completed

The Visceral Adiposity Measurement and Observation Study (VAMOS)

Liver Diseases | BMI | Liver Fat | HIV | NAFLD | Hepatic Fibrosis | Hepatic Steatosis | HIV-1-infection | Liver Fibrosis | NASH | HIV Lipodystrophy | HIV-Associated Lipodystrophy | HIV I Infection | Waist Circumference | HIV Infection Primary | HIV Disease Progression | HIV-Infections | Lipohypertrophy | Ectopic Fat

United States
GE Healthcare
Quintiles, Inc.; Medpace, Inc.; i3 Statprobe; i3 Research

Completed

Assess the Prognostic Usefulness of Flutemetamol (18F) Injection for Identifying Subjects With Amnestic Mild Cognitive Impairment Who Will Convert to Clinically Probable Alzheimer's Disease

Mild Cognitive Impairment | Alzheimer's Disease

United States
Association Pour La Promotion A Tours De La Reanimation...

Unknown

Pharmacokinetics of Nebulized Amikacin in Patients With Pneumonia Undergoing Mechanical Ventilation (DARTAGNAN)

Ventilator Associated Pneumonia

France
Instituto Brasileiro de Controle do Cancer
Wecare Comércio de Cosméticos

Recruiting

Hydration Based on Thoitaine, Aloe Vera and Calendula, in the Prevention of Hand-Foot Syndrome in Patients Using Capecitabine (TACX Care)

Hand-foot Syndrome

Brazil
Corium, Inc.
Worldwide Clinical Trials; Premier Research Group plc; Almac; Prometrika, LLC

Recruiting

A Safety/Tolerability and PK Study With Azstarys® in Children With ADHD (KP415P02)

Attention Deficit/Hyperactivity Disorder

United States
Zurich University of Applied Sciences
Danube University Krems; MedBase Brunngasse Winterthur

Completed

Efficacy of Augmented Feedback on Lumbar Postural and Movement Control During Physiotherapy and Home Exercise

Low Back Pain

Switzerland
4D pharma plc
ICON plc; Labcorp Drug Development Inc

Withdrawn

Study to Assess the Safety of MRx0029 or MRx0005 Compared to Placebo, in People With Parkinson's

Idiopathic Parkinson Disease
University of Hawaii
Kaiser Permanente; RTI International; Centers for Medicare and Medicaid Services and other collaborators

Completed

Hawaii Patient Reward And Incentives to Support Empowerment (HI-PRAISE)

Diabetes Mellitus

United States
Abdul Latif Jameel Poverty Action Lab
Centers for Medicare and Medicaid Services; General Services Administration...

Completed

The Effect of Informative Letters on the Prescription and Receipt of Seroquel

Delivery of Health Care | Economics | Fraud | Health Expenditures | Centers for Medicare and Medicaid Services (U.S.)
GE Healthcare
Medpace, Inc.; Biomedical Systems; i3 Statprobe; Rules-Based Medicine, Inc.

Completed

Safety Study of GE-145 320 mg I/mL Injection vs. Iopamidol 370 mg I/mL in Elderly Subjects Undergoing Coronary Procedure

Diabete Mellitus | Congestive Heart Failure | Chronic Renal Insufficiency

United States
University of Pennsylvania
New York State Department of Health; Centers for Medicare and Medicaid Services

Completed

Medicaid Incentives for the Prevention of Chronic Diseases: Diabetes Prevention (MIPCD)

Diabetes Prevention

United States
Abdul Latif Jameel Poverty Action Lab
Centers for Medicare and Medicaid Services; General Services Administration...

Withdrawn

The Effect of Informative Letters on the Prescription and Receipt of Opioids

Delivery of Health Care | Economics | Fraud | Health Expenditures | Centers for Medicare and Medicaid Services (U.S.) | Prescribing
University Hospital, Basel, Switzerland
Medgate AG, Switzerland; HMO Gesundheitsplan Basel, Switzerland

Completed

Telephone Triage Study

Any Medical Condition Presented by Patient

Switzerland
SeaStar Medical
ICON plc

Recruiting

Neutrophil and Monocyte Deactivation Via the SeLective CytopheretIc Device - A Randomized Clinical Trial in Acute Kidney Injury (NEUTRALIZE-AKI)

Acute Kidney Injury

United States
BioMarin Pharmaceutical
ICON plc

Completed

A Multicenter, Multinational, Observational Morquio A Registry Study (MARS) (MARS)

Mucopolysaccharidosis IV Type A | Morquio A Syndrome | MPS IVA

United States, United Kingdom, Australia, Taiwan, Belgium, Malaysia, Austria, Canada, Portugal, France, Ireland, Czechia, Denmark, Italy, Netherlands, Poland, Puerto Rico
AltruBio Inc.
ICON plc

Completed

A First-In-Human SAD and MAD Study to Evaluate the Safety, Tolerability, PK and PD of SC Administered ALTB-268 in Healthy Volunteers

Healthy Volunteers

United States
Fervent Pharmaceuticals
ICON plc

Completed

FP-101 Versus Placebo in the Treatment of Menopausal Vasomotor Symptoms

Vasomotor Symptoms | Menopause

United States
Biocept, Inc.
ICON plc

Terminated

A Therapy Treatment Response Trial in Patients With Leptomeningeal Metastases ((LM) Using CNSide (FORESEE)

Breast Cancer | Non-Small Cell Lung Cancer | Leptomeningeal Disease | Leptomeningeal Metastasis | Leptomeningeal Neoplasms

United States
Xencor, Inc.
ICON plc

Terminated

Safety and Efficacy of XmAb18087 ± Pembrolizumab in Advanced Merkel Cell Carcinoma or Extensive-stage Small Cell Lung Cancer

Small Cell Lung Cancer | Merkel Cell Carcinoma

United States
Actinogen Medical
ICON plc

Completed

Xanamem™ in Healthy Elderly Subjects (XanaHES)

Cognitive Function | Peripheral Neuropathy | Electrocardiography | Central Nervous System | Safety | Healthy Ageing | Cortisol | Cerebrospinal Fluid | Small Fibre Neuropathy

Australia
HighLife SAS
ICON plc

Recruiting

Expanded Study of the HighLife 28mm Trans-septal Trans-catheter Mitral Valve in Patients With Moderate-severe or Severe Mitral Regurgitation and at High Surgical Risk

Mitral Regurgitation

Belgium, France, Germany, Australia, United Kingdom, Poland
AbbVie
Gedeon Richter Plc.

Completed

Study to Assess Adverse Events and How ABBV-932 Oral Capsules Moves Through the Body of Healthy Adult Participants

Healthy Participants | Generalized Anxiety Disorder (GAD)

United States
GE Healthcare
ICON plc

Completed

A Study to Evaluate the Effectiveness of VIZAMYL™ Reader Training Programme in Europe

Cognitive Impairment

Netherlands, Spain, Austria, Finland, Italy
Xencor, Inc.
ICON plc

Completed

A Study of XmAb®18087 in Subjects With NET and GIST

Neuroendocrine Tumor | Gastrointestinal Neoplasm

United States
Renishaw
Herantis Pharma Plc.

Active, not recruiting

Long-Term Follow-up Safety After DDS Implantation With/Without CDNF Infusions

Brain Diseases | Nervous System Diseases | Parkinson Disease | Movement Disorders | Neuro-Degenerative Disease

Finland, Sweden
GE Healthcare
ICON plc

Completed

Advanced MRI Applications for Mild Traumatic Brain Injury-Phase 2 (mTBI-phase2)

Traumatic Brain Injury | Concussion

United States
Optos, PLC
Optos, Inc.

Unknown

Side-by-Side Comparison of P200TE and Spectral OCT/SLO on Diseased Eyes

Glaucoma | Retinal Disease

United States
Hayat Pharmaceutical Co. PLC

Unknown

Efficacy Evaluation of the (Serodase 5 mg Tablet) in the Treatment of Inflammation After Third Molar Surgery

Inflammation | Trismus | Swelling
Tolmar Inc.
ICON plc

Recruiting

A Phase 4 Study to Evaluate Adrenal Function in Hypogonadal Men Treated With JATENZO® for 12 Months

Hypogonadism

United States
JOTEC GmbH
ICON plc

Recruiting

French Registry Conducted on E-vita OPEN NEO (NEO)

Vascular Aneurysm

France
Xencor, Inc.
ICON plc

Recruiting

A Study of XmAb20717 (Vudalimab)in Patients With Selected Advanced Gynecologic and Genitourinary Malignancies

Ovarian Cancer | Endometrial Cancer | Cervical Carcinoma | Metastatic Castration-Resistant Prostate Cancer (mCRPC) | Clear Cell Carcinoma

United States
Xencor, Inc.
ICON plc

Active, not recruiting

A Study of XmAb®23104 in Subjects With Selected Advanced Solid Tumors (DUET-3) (DUET-3)

Renal Cell Carcinoma | Nasopharyngeal Carcinoma | Small Cell Lung Cancer | Hepatocellular Carcinoma | Advanced Solid Tumors | Non-small Cell Lung Carcinoma | Squamous Cell Carcinoma of the Head and Neck | Cervical Carcinoma | Endometrial Carcinoma | Urothelial Carcinoma | Colorectal Carcinoma | Pancreatic Carcinoma and other conditions

United States
Edwards Lifesciences
ICON plc

Terminated

Observational Registry on the HARPOON Device (REPLICATE)

Severe Degenerative Mitral Regurgitation Due to Mid-segment Posterior Leaflet Prolapse

Germany, Spain, Switzerland
LEO Pharma
ICON plc

Completed

A Single and Multiple Ascending-dose Trial of LEO 153339 in Healthy Adults

Healthy Volunteers

Netherlands
Xencor, Inc.
ICON plc

Completed

A Study of XmAb®20717 in Subjects With Selected Advanced Solid Tumors (DUET-2)

Melanoma | Renal Cell Carcinoma | Cervical Cancer | Nasopharyngeal Carcinoma | Small Cell Lung Carcinoma | Hepatocellular Carcinoma | Thymic Carcinoma | Thymoma | Non-small Cell Lung Carcinoma | Mesothelioma | Squamous Cell Carcinoma of the Head and Neck | Cholangiocarcinoma | Breast Carcinoma | Fallopian Tube Carcinoma and other conditions

United States
Vasopharm GmbH
ICON plc

Completed

Efficacy of VAS203 (Ronopterin) in Patients With Moderate and Severe Traumatic Brain Injury (NOSTRA-III)

Traumatic Brain Injury

United Kingdom, Spain, France, Austria, Germany
GE Healthcare
ICON plc

Completed

Comparative Study of Conventional 1.5 and 3.0T MR Images With Synthetically Reconstructed MR Images

Clinical Indication for Brain MRI

United States
Hayat Pharmaceutical Co. PLC

Unknown

Efficacy of the Dose Regimen of Oral Vitamin D 50,000 IU in the Treatment of Vitamin D Deficiency

Vitamin D Deficiency

Jordan
Arthritis Northwest PLLC
Bristol-Myers Squibb; Discus Analytics LLC

Unknown

Electronic and Lab Pre-screening of New Rheumatology Patients With Rheumatoid Arthritis

Rheumatoid Arthritis | Inflammatory Arthritis
Abdul Latif Jameel Poverty Action Lab
Centers for Medicare and Medicaid Services; General Services Administration...

Completed

The Effect of Informative Letters on the Prescription and Receipt of Schedule II Controlled Substances

Delivery of Health Care | Economics | Fraud | Health Expenditures | Centers for Medicare and Medicaid Services (U.S.)
Washington University School of Medicine
The Foundation for Barnes-Jewish Hospital; Mallinckrodt; Centers for Medicare...

Active, not recruiting

Extracorporeal Photopheresis for Medicare Recipients of Lung Allografts (ECP)

Bronchiolitis Obliterans Syndrome (BOS)

United States

Clinical Trials Sponsored by Medcare Plc

Sponsors and Collaborators

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Drug Interventions

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CROs in Cyprus

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