Clinical Trials Sponsored by Merieux Institute

Total 74442 results

Duke University
National Cancer Institute (NCI); National Institutes of Health (NIH)

Recruiting

Mechanisms of Disease R/R in CAR-T for Hematologic Malignancies

Hematologic Malignancy

United States
National Cancer Institute (NCI)

Recruiting

Study of VIP152, Venetoclax, and Prednisone (VVIP) in Relapsed/Refractory Lymphoid Malignancies

Lymphoma | Non-Hodgkin Lymphoma | NHL | Hematologic Malignancies | Lymphoid Malignancies

United States
National Cancer Institute (NCI)

Recruiting

Comprehensive Molecular and Clinical Evaluation of Pediatric and Adult MDS

Myelodysplastic Syndromes

United States
National Cancer Institute (NCI)

Recruiting

Donor Lymphocyte Infusion After Allogeneic Hematopoietic Cell Transplantation for High-Risk Hematologic Malignancies

Hematologic Neoplasms

United States
Instituto Universitario de Oftalmobiología Aplicada...
Esteve

Recruiting

Efficacy of "Aquoral Lipo" Artificial Tears in Contact Lens Wearers With Discomfort

Contact Lens Complication

Spain
National Cancer Institute (NCI)

Recruiting

Tissue Procurement and Natural History Study of Neuroendocrine Neoplasms (NENs) Including Adrenocortical Carcinoma (ACC)

Neuroendocrine Tumors | Carcinoma, Neuroendocrine

United States
National Cancer Institute (NCI)

Recruiting

18F-DCFPyL Imaging as a Method to Assess Treatment Response to Stereotactic Body Radiation Therapy

Localized Prostate Cancer

United States
National Cancer Institute (NCI)

Recruiting

T Cell Receptor Gene Therapy Targeting KK-LC-1 for Gastric, Breast, Cervical, Lung and Other KK-LC-1 Positive Epithelial Cancers

Kita-kyushu Lung Cancer Antigen 1, Human

United States
Douglas Mental Health University Institute
Canadian Institutes of Health Research (CIHR)

Not yet recruiting

Comparing Standard vs. Modified Reconsolidation Blockade for the Treatment of Psychological Trauma

Trauma and Stressor Related Disorders | Post Traumatic Stress Disorder | Adjustment Disorders | Acute Stress Disorder

Canada
National Cancer Institute (NCI)

Recruiting

Superenhancer Inhibitor Minnelide in Advanced Refractory Adenosquamous Carcinoma of the Pancreas (ASCP)

Adenosquamous Carcinoma of the Pancreas

United States
National Cancer Institute (NCI)

Recruiting

The Effect of Diet and Exercise on ImmuNotherapy and the Microbiome (EDEN)

Melanoma

United States
National Cancer Institute (NCI)

Recruiting

Immunotherapy Combination: Irradiated PD-L1 CAR-NK Cells Plus Pembrolizumab Plus N-803 for Subjects With Recurrent/Metastatic Gastric or Head and Neck Cancer

Gastroesophageal Junction (GEJ) Cancers | Advanced HNSCC

United States
National Cancer Institute (NCI)

Recruiting

Individualized Response Assessment to Heated Intraperitoneal Chemotherapy (HIPEC) for the Treatment of Peritoneal Carcinomatosis From Ovarian, Colorectal, Appendiceal, or Peritoneal Mesothelioma Histologies

Ovarian Cancer | Gastrointestinal Cancer | Peritoneal Carcinomatosis | Peritoneal Mesothelioma | Appendiceal Cancer

United States
Hospital Universitari Vall d'Hebron Research Institute
Instituto de Salud Carlos III

Recruiting

Intestinal Dysmotility in Patients With Functional Digestive Symptoms

Gastrointestinal Motility Disorder

Spain
National Cancer Institute (NCI)

Recruiting

A Natural History Study of Children and Adults With Olfactory Neuroblastoma

Olfactory Neuroblastoma | Esthesioneuroblastoma

United States
National Cancer Institute (NCI)

Recruiting

M9241 in Combination With Docetaxel in Adults With Metastatic Castration Sensitive and Castration Resistant Prostate Cancer

Cancer Of Prostate | Prostate Neoplasms

United States
National Cancer Institute (NCI)

Recruiting

Connect for Cancer Prevention Study (Connect)

Cancer | General Research Use

United States
National Cancer Institute (NCI)

Recruiting

Rapid Analysis and Response Evaluation of Combination Anti-Neoplastic Agents in Rare Tumors (RARE CANCER) Trial: RARE 1 Nilotinib and Paclitaxel

Neoplasms

United States
Stanford University
National Cancer Institute (NCI); National Institutes of Health (NIH)

Recruiting

d-Limonene +Radiation +Platinum Based Chemo for Xerostomia Prevention in Locally Advanced Head and Neck Squamous Cell Carcinoma

Xerostomia

United States
National Eye Institute (NEI)

Recruiting

Autologous Transplantation of Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium for Geographic Atrophy Associated With Age-Related Macular Degeneration

Geographic Atrophy | Dry Age-Related Macular Degeneration

United States
National Cancer Institute (NCI)

Recruiting

Immersive Virtual Reality (VR) at the Time of Clinical Evaluation to Improve Psychological Distress and Anxiety in Primary Brain Tumor (PBT) Patients

Anxiety

United States
National Cancer Institute (NCI)

Recruiting

Front Line Ibrutinib Without Corticosteroids for Newly Diagnosed Chronic Graft-versus-Host Disease

Chronic GVHD

United States
National Cancer Institute (NCI)

Recruiting

Bintrafusp Alfa (M7824) and NHS-IL12 (M9241) Alone and in Combination With Stereotactic Body Radiation Therapy (SBRT) in Adults With Metastatic Non-Prostate Genitourinary Malignancies

Urogenital Neoplasms | Bladder Cancer | Urothelial Cancer | Genitourinary Cancer | Urogenital Cancer

United States
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Recruiting

Canadian Study of Arterial Inflammation in Patients With Diabetes and Vascular Events: EvaluatioN of Colchicine (CADENCE)

Cardiovascular Diseases | Inflammation | Diabetes | Atherosclerosis

Canada
National Cancer Institute (NCI)

Recruiting

Natural History and Management of Von Hippel-Lindau (VHL) Associated Pancreatic Neuroendocrine Tumors

Neuroendocrine Tumors | Von Hippel-Lindau Disease | VHL Pancreatic Neuroendocrine Tumors

United States
National Cancer Institute (NCI)

Recruiting

Acalabrutinib With DA-EPOCH-R or R-CHOP for People With Untreated Diffuse Large B-cell Lymphoma

Diffuse Large B-Cell Lymphoma | Non-Hodgkin's Lymphoma | NHL | DLBCL

United States
National Cancer Institute (NCI)

Recruiting

Studying the Biology of IDH-mutant Gliomas Via Longitudinal Observation of 2-hydroxyglutarate (2-HG) Using MR Spectroscopy

Glioma | High Grade Glioma | Malignant Glioma | Gliomas | Low Grade Glioma

United States
National Cancer Institute (NCI)

Recruiting

Combined Treatment of Durvalumab, Bevacizumab, Tremelimumab and Transarterial Chemoembolization (TACE) in Subjects With Hepatocellular Carcinoma or Biliary Tract Carcinoma

Hepatocellular Carcinoma | Hepatocellular Cancer | Metastatic Hepatocellular Carcinoma

United States
National Cancer Institute (NCI)

Recruiting

Allogeneic Hematopoietic Cell Transplantation for Peripheral T Cell Lymphoma

Immune System Diseases | Lymphoproliferative Disorders | Peripheral T-cell Lymphomas

United States
National Eye Institute (NEI)

Recruiting

Retinitis Pigmentosa Clinical Measures and Repeatability Testing of Potential Outcome Measures

Retinitis Pigmentosa

United States
National Cancer Institute (NCI)

Recruiting

Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12D Variant of Mutated RAS in HLA-A*11:01 Patients

Gastric Cancer | Pancreatic Cancer | Rectal Cancer | Colon Cancer | Gastrointestinal Cancer

United States
National Cancer Institute (NCI)

Recruiting

CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory CD19/CD22-expressing B Cell Malignancies

Lymphoma, Non-Hodgkin | Acute Lymphoblastic Leukemia | Acute Lymphocytic Leukemia | Acute Lymphoid Leukemia | B-Cell Leukemia | Leukemia, Lymphocytic, B Cell | B-Cell Lymphoma | B-All | B-NHL | B-Non Hodgkin Lymphoma

United States
National Cancer Institute (NCI)

Recruiting

The Effects of Castration on the Pharmacokinetics of Zolpidem After Single Dose Administration In Men With Prostate Cancer Undergoing Androgen Deprivation Therapy Compared to Normal Healthy Females

Prostatic Neoplasms

United States
National Cancer Institute (NCI)

Recruiting

Sample Collection and Tracking for the Developmental Therapeutics Clinic

Neoplasms | Lymphoma

United States
National Cancer Institute (NCI)

Recruiting

Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (ViPOR) in Relapsed/Refractory B-cell Lymphoma

Lymphoma | Diffuse Large B-Cell Lymphoma | Burkitt Lymphoma | Non-Hodgkin Lymphoma

United States
National Cancer Institute (NCI)

Recruiting

Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12V Variant of Mutated RAS in HLA-A*11:01 Patients

Gastric Cancer | Pancreatic Cancer | Rectal Cancer | Colon Cancer | Gastrointestinal Cancer

United States
National Cancer Institute (NCI)

Recruiting

Clonal Evolution in Follicular Lymphoma

Follicular Lymphoma

United States
National Cancer Institute (NCI)

Recruiting

A Pilot Study to Investigate the Safety and Clinical Activity of Avelumab (MSB0010718C) in Thymoma and Thymic Carcinoma After Progression on Platinum-Based Chemotherapy

Thymic Carcinoma | Thymoma

United States
National Cancer Institute (NCI)

Recruiting

Hereditary Gastric Cancer Syndromes: An Integrated Genomic and Clinicopathologic Study of the Predisposition to Gastric Cancer

Stomach Neoplasms | Stomach Cancer | Gastric Adenocarcinoma and Proximal Polyposis of the Stomach (GAPPS) | Hereditary Diffuse Gastric Cancer (HDGC) | Familial Diffuse Gastric Cancer

United States
National Cancer Institute (NCI)

Recruiting

Long-Term Follow-up of People Undergoing Hematopoietic Stem Cell Transplantation

Hematopoietic Stem Cell Transplantation | Tissue Donors

United States
Ottawa Hospital Research Institute
Canadian Institutes of Health Research (CIHR); Medtronic

Recruiting

In-clinic Endoscopic Polypectomy for Chronic Sinusitis With Nasal Polyps

Sinusitis | Nasal Polyps

Canada
National Eye Institute (NEI)

Recruiting

Natural History, Pathogenesis, and Outcome of Ocular Disorders

Eye Disease

United States
National Cancer Institute (NCI)

Recruiting

Biospecimen Procurement for Center for Immuno-Oncology Immunotherapy Protocols

Lymphoma, Non-Hodgkin | Multiple Myeloma | Hodgkin Disease | Non-Small Cell Lung Cancer | Leukemia-Lymphoma, Adult T-Cell

United States
National Cancer Institute (NCI)

Recruiting

Alvelestat (MPH966), an Oral Neutrophil Elastase Inhibitor, in Bronchiolitis Obliterans Syndrome After Allogeneic Hematopoietic Stem Cell Transplantation

Bronchiolitis Obliterans Syndrome | Chronic Graft vs Host Disease | Chronic Graft-Versus-Host Disease

United States
National Eye Institute (NEI)

Recruiting

Rod and Cone Mediated Function in Retinal Disease

Retinal Degeneration | Retinitis Pigmentosa | Stargardt's Disease

United States
National Cancer Institute (NCI)

Recruiting

Development and Validation of Patient Reported Outcome (PRO) Measures for Individuals With Neurofibromatosis 1 (NF1) and Plexiform Neurofibromas (pNFs)

Neurofibromatosis 1 | Plexiform Neurofibromas

United States
National Cancer Institute (NCI)

Recruiting

Combination Nilotinib and Paclitaxel in Adults With Relapsed Solid Tumors

Solid Tumors

United States
National Cancer Institute (NCI)

Recruiting

Study of Palifermin (Kepivance) in Persons Undergoing Unrelated Donor Allogeneic Hematopoietic Cell Transplantation

Multiple Myeloma | Hodgkin's Lymphoma | Non-Hodgkin's Lymphoma | Acute Leukemia | Myelodysplastic Syndrome

United States
National Cancer Institute (NCI)

Recruiting

Phase 1 Study of Ibrutinib and Immuno-Chemotherapy Using Temozolomide, Etoposide, Doxil, Dexamethasone, Ibrutinib,Rituximab (TEDDI-R) in Primary CNS Lymphoma

Primary Central Nervous System Lymphoma

United States
National Cancer Institute (NCI)

Recruiting

Trial Evaluating an Enhanced Physical Activity Intervention to Improve Cognitive Late Effects in Children Treated With Cranial Radiation for Brain Tumors

Brain Tumor

United States

Clinical Trials Sponsored by Merieux Institute

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Switzerland

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

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