Clinical Trials Sponsored by The Royal Orthopaedic Hospital NHS Trust

Total 699 results

The Leeds Teaching Hospitals NHS Trust

Completed

SPARC: Shoulder PAtch for Rotator Cuff Tears

Massive Rotator Cuff Tears

United Kingdom
The Leeds Teaching Hospitals NHS Trust

Completed

A Study to Determine the Feasibility and Acceptability of Conducting a Phase III Randomised Controlled Trial Comparing Stereotactic Ablative Radiotherapy With Surgery in paTients With Peripheral Stage I nOn-small Cell Lung Cancer cOnsidered Higher Risk of Complications From Surgical Resection (SABRTOOTHv1)

Oncology

United Kingdom
The Leeds Teaching Hospitals NHS Trust

Unknown

Can Contrast Enhanced Spectral Mammography (CESM) Reduce the Number of Benign Biopsies for Calcifications Without Negatively Impacting on Detection/Diagnosis of Clinically Significant Calcifications (MICROENHANCE)

Mammography

United Kingdom
The Leeds Teaching Hospitals NHS Trust

Completed

Penicillin Allergy De-Labelling in Elective Surgical Patients (PADLES) (PADLES)

Allergy

United Kingdom
The Leeds Teaching Hospitals NHS Trust

Completed

What Effect Does Intubation Have on Regional Lung Ventilation?

Anesthesia

United Kingdom
The Leeds Teaching Hospitals NHS Trust

Unknown

Utilization of NBi in Assessing Luminal INflammaion in IBD (UNBLIND)

Ulcerative Colitis (UC)

United Kingdom
The Leeds Teaching Hospitals NHS Trust

Unknown

Magnetic Resonance Imaging to Assess Changes in Meniscus Vascularity (MOVE)

Meniscus Tears
The Leeds Teaching Hospitals NHS Trust

Unknown

Antibiotic Nephrotoxicity in Adult Patients With Cystic Fibrosis

Cystic Fibrosis

United Kingdom
University of Cambridge
Guy's and St Thomas' NHS Foundation Trust; Manchester University NHS Foundation... and other collaborators

Completed

Observational Cohort Study of a National Extracorporeal Membrane Oxygenation Service for Adults With Respiratory Failure: the NHS ECMO Study. (NHS ECMO)

Acute Respiratory Failure
University Hospitals Dorset NHS Foundation Trust
The Christie NHS Foundation Trust

Recruiting

The ID- RFA Trial: A Trial of Intraductal Radio-frequency Ablation (ID-RFA) Plus Biliary Stenting Versus Biliary Stenting Alone for the Treatment of Malignant Biliary Obstruction.

Malignant Biliary Obstruction

United Kingdom
Royal United Hospitals Bath NHS Foundation Trust
Sheffield Teaching Hospitals NHS Foundation Trust; Royal Free Hospital NHS... and other collaborators

Recruiting

Improving Pulmonary Hypertension Screening by Echocardiography (IMPULSE)

Pulmonary Hypertension

United Kingdom
Videregen Limited
Royal Free Hospital NHS Foundation Trust; Papworth Hospital NHS Foundation... and other collaborators

Not yet recruiting

ENgineered Tissue Repair of BronchopleUral fiSTula (ENTRUST)

Bronchopleural Fistula
University of Manchester
Northern Care Alliance NHS Foundation Trust; Royal Free Hospital NHS Foundation... and other collaborators

Enrolling by invitation

Early Diagnosis of SSc in the General Rheumatology Clinic - Pilot

Systemic Sclerosis | Raynaud Phenomenon

United Kingdom
University of Nottingham
Nottingham University Hospitals NHS Trust; Royal Papworth Hospital

Active, not recruiting

A National Retrospective Population Based Cohort Study of the Natural History of Ataxia Telangiectasia (N-HAT)

Ataxia Telangiectasia

United Kingdom
Barts & The London NHS Trust
London School of Hygiene and Tropical Medicine; King's College Hospital NHS... and other collaborators

Active, not recruiting

Prevention of Dysrhythmias on the Cardiac Intensive Care Unit - Does Maintenance of High-normal Serum Potassium Levels Matter (TIGHT-K)

Arrhythmias, Cardiac

United Kingdom
University of Surrey
Royal Surrey County Hospital NHS Foundation Trust; Ashford and St. Peter's...

Withdrawn

Testing the Accuracy of a Personal Heart Rhythm Monitor to Detect Prolonged Paroxysmal Atrial Fibrillation

Stroke | Paroxysmal Atrial Fibrillation

United Kingdom
Queen Mary University of London
Guy's and St Thomas' NHS Foundation Trust; Barts & The London NHS Trust; Royal... and other collaborators

Active, not recruiting

Implementing Long-Acting Novel Antiretrovirals (ILANA)

Human Immunodeficiency Viruses

United Kingdom
University of Oxford
King's College Hospital NHS Trust; Nottingham University Hospitals NHS Trust; Guy's and St Thomas' NHS Foundation Trust and other collaborators

Enrolling by invitation

Echocardiography: Value and Accuracy at REst and STress (EVAREST)

Coronary Artery Disease | Angina Pectoris | Ischaemic Heart Disease
University Hospitals Bristol and Weston NHS Foundation...
University of Bristol; Royal United Hospital Bath NHS Trust

Completed

Distress Thermometer Intervention Trial (DiTIT)

Cancer

United Kingdom
Royal Free Hospital NHS Foundation Trust
Fisher and Paykel Healthcare; Royal Free Charity

Active, not recruiting

Domiciliary Nasal High Flow and Patient Outcomes in Chronic Hypercapnic Respiratory Failure in the United Kingdom

Chronic Obstructive Pulmonary Disease | Chronic Hypercapnic Respiratory Failure | Health-related Quality of Life | Obesity Hypoventilation Syndrome (OHS) | Nasal High Flow

United Kingdom
University of Dundee
Newcastle-upon-Tyne Hospitals NHS Trust; Oxford University Hospitals NHS Trust and other collaborators

Completed

DIabetes REsearCh on Patient sTratification (DIRECT): GLP-1R Agonists (DIRECTGLP)

Diabetes

United Kingdom
Pier Lambiase
University Hospital Southampton NHS Foundation Trust; The Royal Bournemouth...

Completed

Randomized Trial of Two Ablation Catheters in Paroxysmal Atrial Fibrillation

Atrial Fibrillation

United Kingdom
University of Sheffield
Sheffield Children's NHS Foundation Trust; Alder Hey Children's Hospital NHS... and other collaborators

Completed

Impact of Parental Perfectionistic Cognitions Self-compassion Intervention Effects on Shame in Child Health Context

Epilepsy | Diabetes Mellitus, Type 1 | Stress | Asthma | Shame | Self-Compassion | Perfectionistic Cognitions

United Kingdom
South Tyneside and Sunderland NHS Foundation Trust
Newcastle-upon-Tyne Hospitals NHS Trust; South Tees Hospitals NHS Foundation... and other collaborators

Completed

ObeSity Related Colorectal Adenoma Risk (OSCAR)

Obesity | Colorectal Cancer | Metabolic Syndrome | Colorectal Neoplasm | Colorectal Adenoma | Liver Fibrosis | Non-Alcoholic Fatty Liver Disease

United Kingdom
Royal United Hospitals Bath NHS Foundation Trust
University of Bath; Great Western Hospitals NHS Foundation Trust

Recruiting

Development of a Drill Guidance System to Aid Intra-operative Surgical Drilling

Orthopaedic Surgery

United Kingdom
University of Oxford
Oxford University Hospitals NHS Trust; South Central Ambulance Service NHS... and other collaborators

Completed

Computer Assisted Lessening of Intrusive Memories in the Emergency Department (CALM-ED)

Post Traumatic Stress Disorder

United Kingdom
Imperial College Healthcare NHS Trust
Nottingham University Hospitals NHS Trust; Barts & The London NHS Trust; Hospital... and other collaborators

Completed

Ripple Mapping Guided Ablation of Ischaemic Ventricular Tachycardia. (RIPPLE-VT)

Ischemic Heart Disease | Ventricular Tachycardia

United Kingdom
Barts & The London NHS Trust
East Kent Hospitals University NHS Foundation Trust; Southend NHS Foundation...

Completed

A Clinical Trial of Three Fixed Orthodontic Appliances

Orthodontic Treatment

United Kingdom
University of Leeds
The Leeds Teaching Hospitals NHS Trust; The Christie NHS Foundation Trust

Completed

eRAPID Feasibility Pilot Study in Pelvic Radiotherapy (eRAPID-RT)

Cancer

United Kingdom
North Bristol NHS Trust
Ferring Pharmaceuticals; University of Bristol; University Hospitals Bristol... and other collaborators

Completed

Intramuscular Oxytocics: A Randomised Control Trial (IMox)

Post Partum Haemorrhage

United Kingdom
Innersight Labs Ltd
King's College London; Guy's and St Thomas' NHS Foundation Trust; Sheffield Teaching... and other collaborators

Not yet recruiting

Virtual 3D Modelling for Improved Surgical Planning of Robotic-assisted Partial Nephrectomy (VISP)

Kidney Cancer
Portsmouth Hospitals NHS Trust
University Hospitals, Leicester; Brighton and Sussex University Hospitals NHS... and other collaborators

Unknown

"Using Dilute Vinegar to Find Changes in Cells During Endoscopy for Patients With Barrett's Oesophagus" (The ABBA Study) (ABBA)

Barrett Esophagus

United Kingdom
Royal Free Hospital NHS Foundation Trust
Private Physiotherapy Education Fund

Recruiting

Can Waveform and Flow Traces From Mechanical Insuflattion:Exsufflation (MI:E) be Used to Identify Laryngeal Responses to MI:E and Thus Optimise Treatment Algorithms? (SETTLE)

Neuromuscular Diseases

United Kingdom
Imperial College London
Royal Free Hospital NHS Foundation Trust; Hvivo

Completed

SARS-CoV-2 Human Challenge Characterisation Study

COVID-19 | Covid19 | Corona Virus Infection | SARS-CoV Infection | Coronavirus

United Kingdom
Royal Surrey County Hospital NHS Foundation Trust
University of Surrey

Completed

Enhancing Fitness Before Pancreatic Surgery (MedEx)

Pancreatic Cancer | Pancreatitis, Chronic

United Kingdom
University of Surrey
Royal Surrey County Hospital NHS Foundation Trust

Not yet recruiting

The Remote Study: Investigating the Effects or Online Exercise on Quality of Life in Men With Prostate Cancer

Prostate Cancer

United Kingdom
University of Surrey
Royal Surrey County Hospital NHS Foundation Trust

Terminated

The Cancer Pain and Unmet Needs Study

Cancer

United Kingdom
Royal Surrey County Hospital NHS Foundation Trust
King's College London

Completed

Comfort and Wearability of Custom-fitted, Mouth-formed and Pre-fabricated Mouthguards for Patients Undergoing Fixed Appliance Therapy

Mouth Protectors
Mr Andrew Kent

Completed

Carbon Dioxide-laser Versus Harmonic Scalpel in the Treatment of Pelvic Pain Due to Endometriosis

Endometriosis
Royal Brompton & Harefield NHS Foundation Trust
King's College London; King's College Hospital NHS Trust; Imperial College London and other collaborators

Active, not recruiting

Validation of an Artificial Intelligence Enabled Diagnostic Support Software (ArtiQ.Spiro) in Primary Care Spirometry Datasets - a Retrospective Analysis

Respiratory Disease

United Kingdom
Barts & The London NHS Trust
University College London Hospitals; Barking, Havering and Redbridge University... and other collaborators

Completed

A Study of Outcomes in Patients With Fractured Neck of Femur During the COVID-19 Pandemic

SARS-CoV 2 | Femoral Neck Fractures

United Kingdom
Royal Marsden NHS Foundation Trust
Massachusetts General Hospital; Natera, Inc.

Recruiting

Safe De-escalation of Chemotherapy for Stage 1 Breast Cancer (Safe-De)

Breast Cancer

United Kingdom
Royal Free Hospital NHS Foundation Trust
KCI Europe Holding B.V.

Terminated

Negative Pressure Wound Therapy With Instillation for Treatment of Hidradenitis Suppurativa (HIDRA)

Hidradenitis Suppurativa

United Kingdom
Royal Free Hospital NHS Foundation Trust
British Heart Foundation; Actelion

Unknown

Assessment of Cardiac Function Using Combined Cardiovascular Magnetic Resonance and Cardiopulmonary Exercise Testing (CMR-CPET) (CMR-CPET)

Pulmonary Hypertension

United Kingdom
City, University of London
Royal Free Hospital NHS Foundation Trust

Completed

A Randomised Control Trial of Integrative Cognitive Behavioural Therapy for Alopecia

Alopecia

United Kingdom
University of Surrey
Royal Surrey County Hospital NHS Foundation Trust

Completed

Using a Personal Heart Rhythm Monitor to Diagnose Paroxsymal Atrial Fibrillation in the Community

Stroke | Paroxysmal Atrial Fibrillation

United Kingdom
Odense University Hospital
Royal Marsden NHS Foundation Trust; Aalborg University Hospital

Recruiting

Efficacy and Safety of Infliximab for Immune Checkpoint Inhibitor Induced Colitis (iCaD)

Colitis

Denmark, United Kingdom
Prof Corinne Faivre-Finn
Royal Marsden NHS Foundation Trust; The Leeds Teaching Hospitals NHS Trust; Cambridge... and other collaborators

Completed

Isotoxic Intensity Modulated Radiotherapy (IMRT) in Stage III Non Small Cell Lung Cancer (NSCLC) - A Feasibility Study (Isotoxic-IMRT)

Non Small Cell Lung Cancer

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College London; King's College Hospital NHS Trust; Royal Brompton & Harefield...

Completed

Domiciliary Transcutaneous Electrical Stimulation in Obstructive Sleep Apnoea (TESLA-home)

Obstructive Sleep Apnea

United Kingdom
Royal Marsden NHS Foundation Trust
University College London Hospitals; Great Ormond Street Hospital for Children...

Recruiting

Pelvic Radiation Disease in Childhood Cancer Survivors

Radiation Disease

United Kingdom

Clinical Trials Sponsored by The Royal Orthopaedic Hospital NHS Trust

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