Clinical Trials Sponsored by VGX Pharmaceuticals, LLC

Total 632 results

Hartford Hospital
Optimer Pharmaceuticals LLC

Completed

Study to Assess Inhibition of Spore Production in Patients With C. Difficile Infections: Fidaxomicin Versus Vancomycin

Clostridium Difficile Infection

United States
HealthPartners Institute
Amylin Pharmaceuticals, LLC.

Completed

Use of Continuous Glucose Monitoring Combined With Ambulatory Glucose Profiles to Characterize Glycemic Control

Type 2 Diabetes

United States
Asklepion Pharmaceuticals, LLC
Vanderbilt University

Completed

Intravenous L-Citrulline to Treat Children Undergoing Heart Bypass Surgery

Hypertension, Pulmonary | Heart Defects, Congenital

United States
JHP Pharmaceuticals LLC
Syneos Health

Unknown

Equivalence Study of Tuberculin Purified Protein Derivative in Comparison With a Reference Standard (PPD-S2) (02)

Tuberculosis Identification.
JHP Pharmaceuticals LLC
Syneos Health

Unknown

Dose Study of Tuberculin Purified Protein Derivative (JHP/Dose)

Tuberculosis Infection

United States
SCRI Development Innovations, LLC
Novartis Pharmaceuticals; OSI Pharmaceuticals

Completed

Everolimus and OSI-906 for Patients With Refractory Metastatic Colorectal Cancer

Metastatic Colorectal Cancer

United States
AbbVie
Endo Pharmaceuticals; Allergan Sales, LLC; Acerus Pharmaceuticals Corporation; Upsher-Smith...

Completed

A Study to Evaluate the Effect of Testosterone Replacement Therapy (TRT) on the Incidence of Major Adverse Cardiovascular Events (MACE) and Efficacy Measures in Hypogonadal Men (TRAVERSE)

Cardiovascular Diseases | Hypogonadism

United States, Puerto Rico
Foresee Pharmaceuticals Co., Ltd.
QPS Holdings LLC; Changchun GeneScience Pharmaceutical Co., Ltd.

Recruiting

Efficacy, Safety, and Pharmacokinetics of Leuprolide Mesylate in Subjects With Central Precocious Puberty

Puberty; Precocious, Central

United States, China, Taiwan, Puerto Rico
Janssen Pharmaceutical K.K.
Pharmacyclics LLC.

Completed

A Study to Evaluate the Bruton's Tyrosine Kinase (Btk) Inhibitor PCI-32765 in Patients With Recurrent Mature B-Cell Neoplasms

Recurrent Mature B-cell Neoplasms

Japan
TLL Pharmaceutical, LLC

Withdrawn

Safety and Efficacy Study of TLL018 in the Treatment of Ulcerative Colitis

Ulcerative Colitis

United States
SCRI Development Innovations, LLC
Millennium Pharmaceuticals, Inc.; Aventis Pharmaceuticals

Completed

Weekly Docetaxel and Bortezomib in the Treatment of Advanced Hormone-Refractory Prostate Cancer

Prostate Cancer
TLL Pharmaceutical, LLC

Completed

A Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Study of TLL018, With Food Effect, in Healthy Participants

Healthy

United States
Overseas Pharmaceuticals, Ltd.
GX pharma technology (beijing) Co., Ltd

Active, not recruiting

An Open Label, Balanced, Randomized, 3×3 Latin Square Design Comparing of Brivaracetam Sustained-release Tablets and Brivaracetam Tablets in the Oral Comparative Pharmacokinetic(PK) Study in Chinese Healthy Adult Subjects Under Fasting Conditions.

Partial Seizure

China
University of Utah
AltaThera Pharmaceuticals, LLC

Completed

Prospective Evaluation Analysis and Kinetics Registry (PEAKS)

Atrial Arrhythmia

United States
University at Buffalo
Cubist Pharmaceuticals LLC

Completed

Vancomycin-Associated Nephrotoxicity

Nephrotoxicity

United States
Syndax Pharmaceuticals
Merck Sharp & Dohme LLC

Completed

Continuation Study of Entinostat in Combination With Pembrolizumab in Patients With Advanced Solid Tumors

Neoplasms | Neoplasms by Histologic Type | Lung Diseases | Neoplasms, Glandular and Epithelial | Digestive System Neoplasms | Endocrine Gland Neoplasms | Breast Diseases | Carcinoma, Non-Small-Cell Lung | Lung Neoplasms | Respiratory Tract Neoplasms | Thoracic Neoplasms | Bronchial Neoplasms | Solid Tumors | Renal...

United States
SCRI Development Innovations, LLC
Novartis Pharmaceuticals

Terminated

LBH589 in Refractory Myelodysplastic Syndromes (MDS)

Myelodysplastic Syndromes (MDS)

United States
Merck Sharp & Dohme LLC
Ariad Pharmaceuticals

Terminated

Extension Trial of Deforolimus (Ridaforolimus, MK-8669) in Participants With Advanced Cancer (MK-8669-038)

Advanced Cancers
Koffler Vision Group
Fera Pharmaceuticals, LLC

Terminated

Hydrocortisone Ophthalmic Ointment 0.5% for Treatment of Allergic Conjunctivitis

Allergic Conjunctivitis

United States
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Safety and Efficacy of Mipomersen (ISIS 301012) As Add-on Therapy in High Risk Hypercholesterolemic Patients

Hypercholesterolemia | Coronary Heart Disease

United States
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Single Doses of Mipomersen in Japanese Healthy Volunteers

Healthy Volunteer

Germany
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Dose-escalating Safety Study of ISIS 301012 in Homozygous Familial Hypercholesterolemia Subjects on Lipid Lowering Therapy

Hypercholesterolemia, Familial

United States, Netherlands
Merck Sharp & Dohme LLC
Ariad Pharmaceuticals

Completed

Safety Study of AP23573 in Patients With Advanced, Refractory or Recurrent Malignancies (8669-013)(COMPLETED)

Lymphoma | Multiple Myeloma | Tumors

United States
Merck Sharp & Dohme LLC
Ariad Pharmaceuticals

Completed

Bicalutamide and Ridaforolimus in Men With Prostate Cancer (MK-8669-002)

Prostate Cancer
Merck Sharp & Dohme LLC
Ariad Pharmaceuticals

Completed

Safety, Tolerability and Maximum Tolerated Dose of Oral AP23573 in Combination With Doxorubicin (8669-015)

Sarcoma | Cancer
Merck Sharp & Dohme LLC
Ariad Pharmaceuticals

Completed

Ridaforolimus in Patients With Hepatic Insufficiency (MK-8669-046)

Hepatic Insufficiency | Healthy Volunteers
Merck Sharp & Dohme LLC
Ariad Pharmaceuticals

Completed

AP23573 in Female Adult Patients With Recurrent or Persistent Endometrial Cancer (8669-019)(COMPLETED)

Endometrial Cancer
Merck Sharp & Dohme LLC
Ariad Pharmaceuticals

Completed

Ridaforolimus in Treatment of Sarcoma-SUCCEED (Sarcoma Multi-Center Clinical Evaluation of the Efficacy of Ridaforolimus)(8669-011 AM6) (SUCCEED)

Metastatic Soft-Tissue Sarcomas | Metastatic Bone Sarcomas
Merck Sharp & Dohme LLC
Ariad Pharmaceuticals

Completed

Study of AP23573/MK-8669 (Ridaforolimus), A Mammalian Target of Rapamycin (mTOR) Inhibitor, in Participants With Advanced Sarcoma (MK-8669-018 AM1)(COMPLETED)

Sarcoma, Soft Tissue | Osteosarcoma | Leiomyosarcoma | Liposarcoma | Metastases
University of Pittsburgh
Cubist Pharmaceuticals LLC

Terminated

Cerebrospinal Fluid Pharmacokinetics of Daptomycin

Meningitis

United States
University of Khartoum
Hikma Pharmaceuticals LLC

Completed

Schistosoma Haematobium Infections and Praziquantel

Schistosomiasis

Sudan
Infinity Pharmaceuticals, Inc.
AstraZeneca; MedImmune LLC

Terminated

Study Evaluating IPI-504 in Patients With Gastrointestinal Stromal Tumors (GIST) Following Failure of at Least Imatinib and Sunitinib

Gastrointestinal Stromal Tumors
Diabetes Care Center
Amylin Pharmaceuticals, LLC.

Completed

The Effect of Pramlintide on Meal Time Insulin Bolus

Type 1 Diabetes
St. Justine's Hospital
Graceway Pharmaceuticals, LLC

Completed

A Phase II Study of Imiquimod 5 % Cream for the Treatment of Hemangioma in Infancy

Hemangioma, Capillary

Canada
Primus Pharmaceuticals
ClinOhio Research Services, LLC

Recruiting

Study to Assess Drowsiness, Cognition, Fall Risk After Metaxalone 640 mg and Metaxalone 800 mg

Healthy Participants

United States
Jazz Pharmaceuticals
Merck Sharp & Dohme LLC

Recruiting

JZP898 Intravenous Infusion as Monotherapy and Combination With Pembrolizumab in Adults With Advanced/Metastatic Solid Tumors

Advanced Solid Tumor | Metastatic Solid Tumor

United States
Olix Pharmaceuticals, Inc.
Trial Runners, LLC

Recruiting

Evaluation of OLX10212 in Patients With Neovascular Age-related Macular Degeneration

Neovascular Age-related Macular Degeneration

United States
Amneal Pharmaceuticals, LLC
CBCC Global Research

Recruiting

Bioequivalence Study With Clinical Endpoint Comparing Bimatoprost Ophthalmic Solution 0.01% and LUMIGAN® in the Treatment of Chronic Open-Angle Glaucoma or Ocular Hypertension in Both Eyes.

Ocular Hypertension | Glaucoma, Open-Angle

United States
Aurinia Pharmaceuticals Inc.
United BioSource, LLC

Recruiting

A Prospective Observational Registry of Patients Treated With LUPKYNIS® (Voclosporin) in the US (ENLIGHT-LN)

Lupus Nephritis

United States
University at Buffalo
Amylin Pharmaceuticals, LLC.

Completed

Exeantide in Type 2 Diabetes on Insulin

Type 2 Diabetes

United States
SCRI Development Innovations, LLC
Novartis Pharmaceuticals

Completed

A Study of the Hsp90 Inhibitor AUY922 Plus Capecitabine for the Treatment of Patients With Advanced Solid Tumors

Metastatic or Unresectable Solid Tumor Malignancy

United States
Ironwood Pharmaceuticals, Inc.
Allergan Sales, LLC

Completed

A Study of MD-7246 to Treat Abdominal Pain in Patients With Diarrhea-predominant Irritable Bowel Syndrome

Irritable Bowel Syndrome With Diarrhea (IBS-D)

United States
Massachusetts General Hospital
JayMac Pharmaceuticals, LLC

Completed

EnBrace HR for Depression Treatment and Prevention in Women Trying to Conceive and Early Pregnancy

Depressive Disorder | Pregnancy

United States
University of Oklahoma
Cubist Pharmaceuticals LLC

Completed

Study of the Pharmacokinetics of Daptomycin in Children With Renal Disease

Chronic Kidney Disease | Bacterial Infection

United States
University of Utah
Cubist Pharmaceuticals LLC

Completed

Influence of Rifampin Co-Administration on the Pharmacokinetic Profile of Daptomycin

Pharmacokinetics | Drug Interactions

United States
Biogen
Elan Pharmaceuticals; United BioSource, LLC

Completed

JC-Virus (JCV) Antibody Program (STRATIFY-1)

Multiple Sclerosis

United States
University of Florida
Amylin Pharmaceuticals, LLC.

Completed

Adding Exenatide to Insulin Therapy for Patients With Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease

Type 2 Diabetes Mellitus | Nonalcoholic Fatty Liver Disease

United States
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Safety and Efficacy Study of ISIS 301012 (Mipomersen) Administration in High Risk Statin Intolerant Subjects (ASSIST)

Metabolic Diseases | Dyslipidemias | Lipid Metabolism Disorders | Hypercholesterolemia | Hyperlipidemias | Metabolic Disorder

Netherlands
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Efficacy and Safety Study of ISIS 301012 (Mipomersen) as Add-on in Familial Hypercholesterolemic Patients With Coronary Artery Disease (RADICHOL II)

Coronary Artery Disease | Heterozygous Familial Hypercholesterolemia

United States, Canada
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

An Open-label Extension Study to Assess the Long-term Safety and Efficacy of ISIS 301012 (Mipomersen) in Patients With Familial Hypercholesterolemia or Severe-Hypercholesterolemia

Metabolic Diseases | Congenital Abnormalities | Infant, Newborn, Diseases | Genetic Diseases, Inborn | Dyslipidemias | Metabolism, Inborn Errors | Lipid Metabolism Disorders | Hypercholesterolemia | Hyperlipidemias | Hyperlipoproteinemias | Lipid Metabolism, Inborn Errors | Hyperlipoproteinemia Type II | Metabolic... and other conditions

United States, Canada, Brazil, Taiwan, Singapore, South Africa, United Kingdom

Clinical Trials Sponsored by VGX Pharmaceuticals, LLC

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CROs in Belgium

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