Search clinical trials for: CYP2C19

Total 1130 results

Boehringer Ingelheim

Completed

Drug-drug Interaction Trial Between Rifampicin and BI 409306 in Healthy Volunteers

Healthy

Germany
Pharmtechnology LLC
Altasciences Company Inc.

Completed

Single Dose Crossover Comparative Bioavailability Study of Two Formulations of Fluconazole 200 mg in Healthy Adult Subjects Under Fasting Conditions

Bioequivalence

Canada
CTI BioPharma
Covance

Completed

Drug-Interaction Study to Evaluate the Effect of Rifampin, a Potent CYP3A4 Inducer, on the Systemic Exposure of Pacritinib in Healthy Subjects

Healthy Subjects

United States
University of Colorado, Denver
Merck Sharp & Dohme LLC

Completed

Rifampin and the Contraceptive Implant

Tuberculosis | Contraception

United States
Bristol-Myers Squibb

Withdrawn

Study to Evaluate the Effect of Rifampin on the Drug Levels in Blood and Safety of BMS-986235 in Healthy Participants

Healthy Participants

United States
Boehringer Ingelheim

Completed

A Study in Healthy Men to Test How Fluconazole Influences the Amount of BI 425809 in the Blood

Healthy

Germany
Jiangsu HengRui Medicine Co., Ltd.

Active, not recruiting

A Study to Evaluate the Efficacy and Safety of SHR8008 vs. Fluconazole in Subjects With Acute Vulvovaginal Candidiasis

Acute Vulvovaginal Candidiasis

China
Scynexis, Inc.

Completed

Dose-Finding Study of Oral Ibrexafungep (SCY-078) vs. Oral Fluconazole in Subjects With Acute Vulvovaginal Candidiasis (DOVE)

Candida Vulvovaginitis

United States
SecuraBio

Completed

Phase 1 Study in Healthy Subjects to Evaluate the Effect of Rifampin on the Pharmacokinetics of IPI-145 (DDI)

Healthy

United States
Shanghai Public Health Clinical Center
Yunnan Provincial Infectious Disease Hospital; The Second Hospital of Nanjing...

Completed

Dosing of Tenofovir and Efavirenz in Antiretroviral Therapy

HIV Infections

China
Hoffmann-La Roche

Completed

A Study to Investigate the Effect of Rifampicin on the PK of Multiple Doses of Balovaptin In Healthy Volunteers

Healthy Volunteers

Netherlands
Eli Lilly and Company

Completed

A Study of LY2835219 in Healthy Participants

Healthy Volunteers

United States
Radboud University Medical Center
European and Developing Countries Clinical Trials Partnership (EDCTP); Department... and other collaborators

Completed

Safety, Tolerability, Extended Early Bactericidal Activity and PK of Higher Doses Rifampicin in Adults With Pulmonary TB (HR1)

Pulmonary Tuberculosis (TB)

South Africa
Germans Trias i Pujol Hospital

Completed

Modification of Doses of Efavirenz According to Its Blood Concentration in HIV Patients

HIV

Spain
Laboratorio Elea Phoenix S.A.

Completed

Bioequivalence Study of Two Formulatiosns With the Asscociaton of Efavirenz, Emtricitabine and Tenofovir

Healthy

Argentina
National Hospital for Tropical Diseases, Hanoi,...
Centers for Disease Control and Prevention; Hospital for Tropical Diseases,...

Unknown

Vietnam Cryptococcal Retention in Care Study - Version 2.1

HIV/AIDS | Mycosis Fungoides | Cryptococcosis | Cryptococcal Meningitis | Opportunistic Infections, HIV Related | Mycosis; Opportunistic

Vietnam
National Institute of Allergy and Infectious Diseases...

Completed

TMC207 +/- Rifabutin/Rifampin

Tuberculosis

United States
Tibotec Pharmaceuticals, Ireland

Completed

TMC278-TiDP6-C209: A Clinical Trial in Treatment Naive HIV-1 Patients Comparing TMC278 to Efavirenz in Combination With Tenofovir + Emtricitabine.

HIV Infections | HIV-1 | Human Immunodeficiency Virus Type 1

United States, Australia, France, United Kingdom, Taiwan, Spain, Argentina, Portugal, Romania, South Africa, Canada, Denmark, Sweden, Netherlands, Brazil, Puerto Rico, Austria, Russian Federation, Thailand, Mexico
Centers for Disease Control and Prevention
Sanofi

Completed

TBTC Study 29: Rifapentine During Intensive Phase Tuberculosis (TB) Treatment

Pulmonary Tuberculosis

Uganda, United States, South Africa, Brazil, Canada, Spain
Bristol-Myers Squibb

No longer available

An Expanded Access Study of Oral Liquid Efavirenz in the Treatment of Children With HIV Infection: Canada

HIV Infection

Canada
Dr. Reddy's Laboratories Limited

Completed

Bioavailability Study of Fluconazole Tablets 200 mg Under Fed Conditions

Healthy

Canada
Bamrasnaradura Infectious Diseases Institute
Chulalongkorn University; Mahidol University

Completed

Efavirenz-based Versus Nevirapine-based Antiretroviral Therapy Among HIV-infected Patients Receiving Rifampin (N2R)

HIV Infections | Tuberculosis

Thailand
Stanford University

Terminated

A Study to Determine the Best Dose of Antivirals in Patients With Both TB and HIV (OPTI-NNRTI)

HIV Infections | Tuberculosis

Brazil
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Itraconazole Compared With Fluconazole to Prevent Infections in Patients Undergoing Peripheral Stem Cell or Bone Marrow Transplantation

Cancer

United States
University of Oklahoma

Recruiting

Endothelial Derived Hyperpolarization Factor and Vascular Control

Healthy

United States
Kyoto University
Pfizer; Astellas Pharma Inc

Withdrawn

Fluconazole Versus Micafungin for Candida Bloodstream Infection in Non-Neutropenic Patients

Sepsis | Candidiasis

Japan
Basilea Pharmaceutica

Not yet recruiting

A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Participants With Candidemia and/or Invasive Candidiasis

Candidemia | Candidiasis, Invasive
Maastricht University Medical Center

Not yet recruiting

Fluconazol Versus Medical Honey in the Treatment of Recurrent Vulvovaginal Candidiasis

Candidiasis, Vulvovaginal | Recurrent Candidiasis of Vagina
Daniel Benjamin
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Fluconazole Prophylaxis for the Prevention of Candidiasis in Infants Less Than 750 Grams Birthweight

Candidiasis

United States
Pfizer

Terminated

A Study Of The Efficacy And Safety Of Anidulafungin Vs. Fluconazole In The Treatment Of Patients With Candidemia And/Or Other Forms Of Invasive Candidiasis

Candidemia

China
Dr. Reddy's Laboratories Limited

Completed

Bioavailability Study of Fluconazole Tablets 200 mg Under Fasting Conditions

Healthy

Canada
Children's Hospital of Philadelphia
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Rifampin in CYP24A1-related Hypercalcemia and Hypercalciuria (RICHH)

Genetic Disease | Hypercalciuria | Idiopathic Infantile Hypercalcemia - Mild Form | Idiopathic Infantile Hypercalcaemia - Severe Form | Hypercalcemia, Idiopathic, of Infancy | Hypercalciuric Hypercalcemia

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

Effect of Rifampicin on the Pharmacokinetics of HRS-1167 in Healthy Subjects

Advanced Solid Tumor

China
Institute of Tropical Medicine, Belgium
Leiden University Medical Center; Damien Foundation; Instituto Fernandes Figueira and other collaborators

Completed

Post ExpOsure Prophylaxis for LEprosy in the Comoros and Madagascar (PEOPLE)

Leprosy

Comoros, Madagascar
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Investigate the Effect of Rifampicin on the Uptake and Breakdown of ACT-246475 in Healthy Subjects

Healthy Subject

Netherlands
ProFem GmbH
Montavit Ges.m.b.H.

Active, not recruiting

A Phase IIb/III Study of Prof-001 for the Treatment of Patients With Recurrent Vulvovaginal Candidiasis (RVVC)

Recurrent Vulvovaginal Candidiasis

Austria, Poland, Slovakia
Yale University
Gilead Sciences

Withdrawn

A Study of the Pharmacokinetic and Pharmacodynamic Interactions Between Bictegravir, Tenofovir Alafenamide and Rifapentine in Healthy Adult Subjects

Tuberculosis | Hiv

United States
Pfizer

Completed

Diflucan Bioequivalence Study For Transferring The Manufacture

Bioequivalence

Korea, Republic of
Radboud University Medical Center
St. Antonius Hospital

Completed

Fluconazole Pharmacokinetics, Including Bioavailability, in Obese Subjects After an Intravenous and Oral Administration (FOLIA)

Obesity | Candidiasis | Invasive Fungal Infections | Fluconazole

Netherlands
Millennium Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Effect of Single-Dose Intravenous Rifampin as a Prototypic Inhibitor of Organic Anion Transporting Polypeptide (OATP) 1B1 and OATP1B3 on the Single-Dose Pharmacokinetics (PK) of Oral TAK-906 in Healthy Adult Participants

Healthy Volunteers

United States
R-Pharm

Completed

Effect of Rifampin on the Pharmacokinetics of Ixabepilone in Patients With Advanced Cancer

Neoplasms | Advanced Solid Tumors

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Drug-drug Interaction Trial to Evaluate the Pharmacokinetics Effect of Rifampicin on Famitinib

Healthy Adult Subjects

China
Eli Lilly and Company

Completed

A Drug Interaction Study of LY3154207 in Healthy Participants

Healthy

United States
Global Alliance for TB Drug Development

Completed

PK Interaction Between Rifapentine or Rifampicin and a Single Dose of TMC207 in Healthy Subjects (TMC207-CL002)

Tuberculosis

United States
National University Hospital, Singapore

Suspended

Whole Blood Bactericidal Activity (WBA) Against Mycobacterium Tuberculosis of Rifampicin in Healthy Volunteers

Tuberculosis

Singapore
Eisai Limited

Completed

To Assess the Effect of Rifampicin on the Pharmacokinetics of Eribulin Mesylate in Participants With Advanced Solid Tumors

Tumor

Netherlands
Indiana University
Janssen Services, LLC

Completed

Efavirenz Versus Rilpivirine on Vascular Function, Inflammation, and Oxidative Stress

Cardiovascular Disease

United States
Astellas Pharma Inc

Completed

Comparative Trial of Micafungin Versus Fluconazole for Treating Esophageal Candidiasis

Candidiasis, Oral

South Africa, Brazil, Peru
Pfizer
ViiV Healthcare

Terminated

A Long Term Safety Study Of Lersivirine For The Treatment Of HIV-1 Infection In Subjects Who Have Completed Treatment With Lersivirine In Studies A5271015 And A5271022

HIV-1

South Africa, Australia, United Kingdom, Canada, Italy, Poland, Switzerland, Mexico, Brazil
Tibotec, Inc
Tibotec Therapeutics, a Division of Ortho Biotech Products, L.P., USA

Completed

A Phase I, Open-label Trial to Explore the Pharmacokinetics, Safety and Tolerability of TMC278 (Rilpivirine) 25 mg Once Daily Following a 2-week Period Receiving Efavirenz, in Healthy Male and Female Volunteers

HIV

Search clinical trials for: CYP2C19

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Argentina

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations