Search clinical trials for: Haemophilia A prophylaxis pharmacokinetic dosing

Total 498080 results

Norwegian University of Science and Technology

Completed

Double Bedtime Dosing During Immediate-release Morphine Administration to Cancer Patients

Cancer

Norway
H. Lundbeck A/S

Completed

Pharmacokinetics Properties of Single Oral Dosing of Lu AE58054 in Subjects With Hepatic Impairment (Mild and Moderate) and in Healthy Subjects

Heptic Impairment

Germany
Universitaire Ziekenhuizen KU Leuven
Institutul Clinic Fundeni

Completed

A New Dosing Regimen for Posaconazole Prophylaxis in Children Based on Body Surface Area

Hematological Malignancy

Belgium, Romania
Solvay Pharmaceuticals
Wyeth is now a wholly owned subsidiary of Pfizer; H. Lundbeck A/S

Completed

Twice Daily Titration Study of Bifeprunox in Subjects With Schizophrenia

Schizophrenia | Schizoaffective Disorder

United States
Universitaire Ziekenhuizen KU Leuven

Unknown

Pharmacokinetics of Posaconazole in Allogeneic Transplant Patients With Mucositis

Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)

Belgium
AstraZeneca

Completed

Safety, Pharmacokinetics and Pharmacodynamics After Single and Multiple Dosing of AZD5423 in Japanese Healthy Male Subjects

Healthy

Japan
Jules Bordet Institute

Unknown

Effectiveness of Reduced GCSF Dosing in Patients With a Low to Moderate Risk of Febrile Neutropenia (PAPALDO)

Breast Cancer

Belgium
Sanofi

Terminated

Pharmacokinetics, Pharmacodynamics and Safety Evaluation of SAR279356 in Intensive Care Unit Mechanically Ventilated Patients

Infection Prophylaxis

United States
St. James's Hospital, Ireland
Baxter BioScience

Unknown

Subclinical Joint Bleeding in Irish Adults With Severe Haemophilia A on Personalised Prophylaxis Regimens (PERSONAL)

Severe Haemophilia A

Ireland
University of Oslo School of Pharmacy
Rikshospitalet University Hospital

Completed

Computer Guided Doing of Tacrolimus in Renal Transplantation (OPTIMAL)

Renal Transplantation

Norway
Hospital Israelita Albert Einstein

Unknown

Evaluation of Plasmatic Levels of Busulfan in Patients Undergoing Hematopoietic Stem Cell Transplantation

Acute Leukemia | Immunodeficiency | Chronic Leukemia | Lymphoproliferative Disease | Myeloproliferative Disease

Brazil
Novo Nordisk A/S

Completed

A Trial Investigating the Pharmacokinetics and Pharmacodynamics of rFVIIa in Patients With Haemophilia A or B With or Without Inhibitors

Congenital Bleeding Disorder | Haemophilia A With Inhibitors | Haemophilia B With Inhibitors | Haemophilia A | Haemophilia B

Spain
Bio Products Laboratory

Completed

A Study to Compare the Pharmacokinetics and Safety of Replenine®-VF, Replenine® or Other Factor IX in Haemophilia B

Haemophilia B

United Kingdom
Boehringer Ingelheim

Completed

Study to Evaluate the Effect of Multiple Doses of BIRT 2584 XX Tablets on the Pharmacokinetic Parameters of Warfarin, Omeprazole, Caffeine, and Dextromethorphan in Healthy Male Volunteers

Healthy
Rigshospitalet, Denmark
The University of Queensland

Unknown

Meropenem and Ciprofloxacin Dosing in Septic Shock

Septic Shock

Denmark
Ottawa Hospital Research Institute
LEO Pharma

Completed

A Comparison of Dalteparin and Tinzaparin for Prevention of Blood Clots in Hemodialysis Patients on Oral Anticoagulants Having Surgery

Hemodialysis | Thromboembolism

Canada
Taipei Veterans General Hospital, Taiwan
Taipei City Hospital

Completed

Frequent Dosing of CERA Improves Nutrition and Inflammation in Hemodialysis Patients

Inflammation | Anemia | Malnutrition

Taiwan
Astellas Pharma Inc

Completed

A Study of Safety and Pharmacokinetics of Repeated Dose of Micafungin as Antifungal Prophylaxis in Children and Adolescents Who Undergo Hematopoietic Stem Cell Transplant

Fungal Infections

United States
Novo Nordisk A/S

Completed

Investigating Safety and Pharmacokinetics of NNC 0128-0000-2011 Compared to NNC 0128-0000-2021 in Healthy Male Subjects

Congenital Bleeding Disorder | Haemophilia A | Haemophilia B

United Kingdom
Sutep Jaruratanasirikul
Prince of Songkla University

Completed

Population Pharmacokinetics and Monte Carlo Dosing Simulations of Meropenem During the Early Phase of Severe Sepsis and Septic Shock in Critically Ill Patients in Intensive Care Units

Initial Phase of Severe Sepsis and Septic Shock

Thailand
Green Cross Corporation
Atlantic Research Group

Unknown

Safety, Efficacy and Pharmacokinetics of GreenGene™ F to Previously Treated Patients With Severe Hemophilia A

Hemophilia A

United States, Canada, New Zealand, Poland, Russian Federation, Ukraine, United Kingdom
Bristol-Myers Squibb

Completed

Study to Evaluate Effect of Belatacept on Pharmacokinetics of Inje Cocktail in Healthy Volunteers

Transplant Rejection

United States
AstraZeneca

Completed

Investigating Safety, Tolerability and Efficacy of AZD5363 in Prostate Cancer. (PYRUS)

Metastatic Castrate-Resistant Prostate Cancer (mCRPC), | Efficacy, | Safety and Tolerability, | Pharmacokinetics, | Pharmacodynamics, | Tumour Response.

United Kingdom, United States
University of Illinois at Chicago
American College of Clinical Pharmacy

Completed

Digoxin Dosing in Heart Failure: A Simplified Nomogram Versus Standard Care

Heart Failure

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Pharmacokinetics and Safety of Methylphenidate HCl in Healthy Japanese Adult Male Volunteers

Healthy

United States
Pfizer

Withdrawn

Study Of Safety, Tolerability And Effects Of PF-05175157 In Adults With Moderate To Severe Acne Vulgaris

Acne Vulgaris
Sarepta Therapeutics, Inc.
United States Department of Defense

Completed

A Study to Assess the Safety, Tolerability and Pharmacokinetics of AVI-7288 in Healthy Adult Volunteers

Marburg Hemorrhagic Fever

United States
Rijnstate Hospital

Unknown

Validation of an Adjusted Dosing Algorithm of Carboplatin

Cancer

Netherlands
Genzyme, a Sanofi Company

Completed

Dose Escalation Study to Assess the Safety and Tolerability of Genz-644282 in Patients With Solid Tumors

Solid Tumors

United States
Damanhour University

Completed

Linezolid Pharmacokinetics In Patients With Impaired Renal Function (PPT6) (LZDPPT6)

Renal Failure | Impaired Renal Function
US Department of Veterans Affairs

Terminated

Personalized Warfarin Dosing by Genomics and Computational Intelligence

Myocardial Infarction | Venous Thrombosis | Atrial Fibrillation

United States
Werner J. Heinz
Merck Sharp & Dohme LLC

Completed

Pharmacokinetic, Safety and Efficacy of Intermittent Application of Caspofungin for Antifungal Prophylaxis (CASPHYLAX)

Fungal Infection

Germany
Virobay Inc.
LEO Pharma

Completed

Safety Study of VBY-891 in Healthy Volunteers After Single or Multiple (7 Days) of Oral Dosing (VBY891P1)

Healthy

United States
Virobay Inc.

Completed

Safety Study of VBY-036 in Healthy Volunteers After 7 Days of Oral Dosing (VBY036P1B)

Healthy

United States
U.S. Army Medical Research and Development Command

Completed

Weekly Dosing of Malarone ® for Prevention of Malaria (MALWEEK)

Malaria

United States
Massachusetts General Hospital
McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Completed

Study Examining Repeat Dosing of OROS® Methylphenidate (CONCERTA®) and Immediate Release Methylphenidate in Healthy Adults

Healthy

United States
Alcon Research

Completed

Pharmacokinetic Evaluation of Moxifloxacin in Vigadexa® in Aqueous Humor Samples Following Preoperative Antibiotic/Steroid Dosing in Cataract Surgery Patients

Cataract
Astellas Pharma Inc

Completed

A Clinical Study to Assess the Effect on Pharmacokinetics of Dosing Mirabegron (YM178) and Solifenacin Simultaneously

Healthy Volunteers | Pharmacokinetics of Mirabegron

France
French National Agency for Research on AIDS and...

Completed

Pharmacokinetics of Rifabutin Combined With Antiretroviral Therapy in Patients With TB/HIV Co-infection in Vietnam

HIV Infections | Tuberculosis

Vietnam
Astellas Pharma Inc

Completed

A Study in Healthy Young Men to Look at What Drives the Cardiovascular Effects After Dosing With Mirabegron.

Healthy Volunteers | Pharmacodynamics of Mirabegron

France
Astellas Pharma Inc

Completed

A Study to Find Out How Much Mirabegron Gets Into the Body After Dosing With a Tablet Formulation

Healthy Subjects | Bioavailability | Pharmacokinetics of Mirabegron

Netherlands
West Virginia University

Withdrawn

Serum and Tissue Cefazolin Concentrations in Normal Weight Patients Undergoing Cesarean Delivery.

Infection | Antibiotic Prophylaxis | Cesarean Delivery

United States
University of California, San Francisco

Completed

Cotinine Metabolism in Infants and Children (1058)

Secondhand Smoke Exposure

United States
MedImmune LLC

Completed

A Study to Evaluate the Safety, Tolerability, and Immunogenicity of Motavizumab (MEDI-524) After Dosing for a Second Season in Children

Motavizumab Administration for a Second Season for RSV Prophylaxis

Chile, Brazil
Tibotec Pharmaceuticals, Ireland

Completed

TMC435350-TiDP16-C105: Phase I, 3-way Crossover, Drug-drug Interaction Between TMC435350 and Rifampin After Multiple Dosing.

Hepatitis C | Tuberculosis | Pharmacokinetics | HCV | Rifampin
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Unknown

rFVIIa Prophylaxis in Children With Hemophilia A and Inhibitors (ENJOIH)

Hemophilia A With Inhibitors

United States, Germany, France, Italy, Romania, Spain
Sarepta Therapeutics, Inc.
United States Department of Defense

Withdrawn

A Study to Assess the Safety, Tolerability and Pharmacokinetics of AVI-7537 in Healthy Adult Volunteers

Ebola Hemorrhagic Fever

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Relative Bioavailability Study of Rabeprazole Sodium Administered With Different Dosing Vehicles in Healthy Adult Volunteers

Healthy
Janssen Research & Development, LLC

Completed

A Study of Doripenem in Infants Less Than 12 Weeks of Age

Bacterial Infections

United States, United Kingdom, Belgium
AstraZeneca

Completed

A Randomized, Open Label Study to Compare the Current Phase II and Planned Phase III Capsule Formulation of AZD6244 (AZD6244Formula)

Healthy Volunteers

United States

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