Search clinical trials for: Severe

Total 8595 results

Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Intranasal Sufentanil for Analgesia of Severe Sickle Cell Vaso-occlusive Pain Crisis in the Pediatric (INVOPE)

Vaso-occlusive Crisis
University Hospital, Limoges

Recruiting

Trial Evaluating the Rate of Pneumothorax in Severe Emphysema Secondary to Endoscopic Volume Reduction With Two-stage ZEPHYR® Valves Versus Endoscopic Volume Reduction With One-stage ZEPHYR® Valves (REPEAT)

COPD

France
Sanofi

Recruiting

A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis (COAST 2)

Dermatitis Atopic

Argentina, Japan, China, Czechia, Spain, United States, South Africa, United Kingdom, Denmark, Sweden, Turkey
University of Wisconsin, Madison

Not yet recruiting

Fetoscopic Endoluminal Tracheal Occlusion for Severe Left and Right Congenital Diaphragmatic Hernia

Congenital Diaphragmatic Hernia

United States
Xuanwu Hospital, Beijing

Not yet recruiting

Chinese Severe Brain Injury Trial (CSBIT)

Severe Brain Injury
Amsterdam University Medical Centers (UMC), Location...
Amsterdam UMC, location VUmc; Flevoziekenhuis

Recruiting

Towards Novel BIOmarkers to Diagnose SEPsis on the Emergency Room (BIOSEP)

Infections | Sepsis | Septic Shock | Infection, Bacterial | Sepsis, Severe | Infection Viral | Infections, Respiratory

Netherlands
Hospital Universitario La Paz

Not yet recruiting

VARC-TAVI VALVE IMPLANTATION) (VARC-TAVI)

Severe Aortic Stenosis | Vascular Complications | TAVI\(Transcatheter Aortic Valve Implantation\)
Eli Lilly and Company

Recruiting

A Study of LY3972406 in Adult Participants With Moderate-to-Severe Plaque Psoriasis

Plaque Psoriasis

United States
Seoul National University Hospital

Recruiting

Rezum for 30-80ml Patients With Moderate-severe LUTS to Study Surgical Principles for Median Lobe Enlargement

Prostatic Hyperplasia of the Medial Lobe

Korea, Republic of
Mabwell (Shanghai) Bioscience Co., Ltd.

Recruiting

Study to Evaluate the Pharmacokinetic Characteristics, Safety, Tolerability, and Preliminary Efficacy of 9MW1911 in Patients With Chronic Obstructive Pulmonary Disease (COPD).

Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

China
University Hospital, Strasbourg, France

Recruiting

Monitoring of Intracranial Hemorrhage in Non-severe Head Trauma Patients Hospitalized in the UHCD (Head-Trauma)

Head Trauma

France
Second Affiliated Hospital, School of Medicine,...

Recruiting

Comparison of a Single Versus Double Perclose Technique for TAVR (Single)

Severe Aortic Stenosis

China
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Recruiting

Evaluation of 611(Recombinant Humanized Anti-interleukin-4 Receptor Alpha IgG4 Monoclonal Antibody) in Chinese Adults With Moderate to Severe Atopic Dermatitis

Dermatitis, Atopic

China
Massachusetts General Hospital
Patient-Centered Outcomes Research Institute; University of Colorado, Denver; Emory University and other collaborators

Not yet recruiting

Promoting Shared Decision Making for Severe Aortic Stenosis (IMPACT SDM)

Aortic Stenosis

United States
Henan Institute of Cardiovascular Epidemiology

Recruiting

A Prospective Cohort Study of PCI Strategies for Severely Calcified Lesions of Complex Coronary Arteries in the Elderly (PSSCCE)

Coronary Heart Disease

China
St. Antonius Hospital

Recruiting

Future Optimal Research and Care Evaluation - Aortic Stenosis (FORCE-AoS)

Severe Aortic Valve Stenosis | Moderate Aortic Valve Stenosis

Netherlands
St. Antonius Hospital
ZonMw: The Netherlands Organisation for Health Research and Development; Pitié-Salpêtrière...

Recruiting

Personalized, CT-guided Antithrombotic Therapy Versus Lifelong Single Antiplatelet Therapy to Reduce Thromboembolic and Bleeding Events in Non-atrial Fibrillation Patients After Transcatheter Aortic Valve Implantation (POP ATLANTIS)

Severe Aortic Valve Stenosis

Netherlands
Shanghai Yueyang Integrated Medicine Hospital

Not yet recruiting

The Relationship Between Moderate-to-severe Psoriasis and Sleep Disturbance

Moderate-to-severe Psoriasis

China
University Hospital, Rouen

Not yet recruiting

Interest of the Chair Lift Test in the Prognostic Evaluation of Pulmonary Embolism: a Single-center Open Prospective Study (SIT-EP)

Non-severe Pulmonary Embolism
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Metabolic Reprogramming in Renal Tubular Cells in Acute Kidney Injury Following Severe Trauma (METAKIT)

Multi-organ Failure After Severe Trauma

France
Ain Shams University

Recruiting

Value of Early Post Operative Amino Acids in Critically Ill Obstetrics on Recovery Enhancement

Critical Illness | Patient Satisfaction | Postpartum Disorder | Malnutrition; Protein | Malnutrition in Pregnancy

Egypt
Central South University

Recruiting

Clinical Study of Individualized Vancomycin Dosing Based on Population PK Model

Severe Infection

China
Keymed Biosciences Co.Ltd

Not yet recruiting

Study of CM310 in Children Subjects With Moderate-to-severe Atopic Dermatis

Atopic Dermatitis
First Affiliated Hospital of Wannan Medical College

Recruiting

Time-restricted Enteral Nutrition Versus Continuous Enteral Nutrition in Patients With Severe Stroke

Stroke | Time Restricted Feeding

China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
First Affiliated Hospital, Sun Yat-Sen University; First Affiliated Hospital... and other collaborators

Recruiting

TEER for Severe DMR of Low to Intermediate Surgery Risk

Mitral Regurgitation

China
University Hospital, Strasbourg, France

Recruiting

Non-opioid Anesthesia in Bariatric Surgery (BARIA)

Severe Obesity

France
Vanderbilt University Medical Center

Not yet recruiting

GLP-1 Receptor Agonists Post-Bariatric Surgery (GRABS) Feasibility Trial (GRABS-0)

Severe Obesity

United States
Brugmann University Hospital

Not yet recruiting

Psilocybin-Assisted Therapy for Severe Alcohol Use Disorder

Severe Alcohol Use Disorder
Centre Hospitalier Universitaire, Amiens
CH Montdidier

Recruiting

Intestinal Microbiota Profiling in Severe Acute Alcoholic Hepatitis Patients (HepatAlc-IM)

Corticosteroids | Intestinal Microbiota | Alcohol | Severe Acute Alcoholic Hepatitis

France
Guangzhou JOYO Pharma Co., Ltd
Chengdu JOYO pharma Co., Ltd.

Not yet recruiting

A Study to Evaluate JYP0061 Tablets in Patients With Moderate-to-severe Atopic Dermatitis

Moderate-to-severe Atopic Dermatitis
Chulalongkorn University

Recruiting

Comparison of Outcomes Between Low Dose Emicizumab and Factor VIII in Clinically Severe Hemophilia A

Joint Bleed | Severe Hemophilia A Without Inhibitor

Thailand
University of Manitoba

Recruiting

Post Spinal Hemodynamic Changes in Aortic Stenosis and Mitral Regurgitation by VIS Index and Echocardiography

Severe Aortic Valve Stenosis | Severe Mitral Valve Regurgitation

Canada
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Role of Extended Low Dose Prednisolone in Achieving Clinical and Biochemical Remission in Steroid Responsive Severe Alcoholic Hepatitis

Severe Alcoholic Hepatitis

India
Washington University School of Medicine
Kamuzu University of Health Sciences; Project Peanut Butter; Balchem Corporation

Recruiting

Choline to Improve Malnutrition and Enhance Cognition (CHIME-SAM)

Cognitive Impairment | Wasting | Severe Acute Malnutrition | Kwashiorkor

Malawi
Shanghai Chest Hospital

Not yet recruiting

A Multi-center RCT to Evaluate Subsegmental BTVA Treatment for Severe Emphysema (BTVA)

Severe Emphysema
University of Saskatchewan

Not yet recruiting

Examining the Effects of a Remote Pulmonary Rehabilitation Program in the Severe Asthma Population. (STAPLE)

Asthma
UCB Biopharma SRL

Not yet recruiting

A Study of Rozanolixizumab in Pediatric Study Participants With Moderate to Severe Generalized Myasthenia Gravis (roMyG)

Generalized Myasthenia Gravis
St. Joseph's Healthcare Hamilton
Trudell Medical International

Not yet recruiting

Effect of OPEP on Mucus Plugging and Airflow Obstruction in Patients With Moderate-to-severe Asthma (AeroMUC)

Asthma

Canada
Sanofi

Recruiting

A Study to Test a Medicine (Fitusiran) for Preventing Bleeds in People With Severe Hemophilia Who Previously Received Preventive Treatment With Emicizumab

Hemophilia A

Taiwan
Artcline GmbH
ZKS Jena

Recruiting

Recovery From Acute Immune Failure in Septic Shock by Immune Cell Extracorporeal Therapy - Observational Long-term Outcome Follow up (ReActIF- LTO)

Severe Sepsis

Germany
London North West Healthcare NHS Trust

Recruiting

CArE for OAsI Study: Care Pathways and Anorectal Evaluation for OASI Associated Incontinence (CArE for OAsI)

Anal Incontinence | Faecal Incontinence | Follow-up | Biofeedback | Obstetric Anal Sphincter Injury | Urogynaecology | Urgency | Severe Perineal Trauma | Grade 3 Perineal Tear | Grade 4 Perineal Tear | Deferral Time | Pathways | Review | Endo-anal Ultrasound

United Kingdom
Janssen Research & Development, LLC

Recruiting

A Study of JNJ-77242113 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis

Plaque Psoriasis

Korea, Republic of, United Kingdom, United States, Poland, Germany, Brazil, Spain, Taiwan, Hungary, Japan, Canada, Argentina, Australia
Apex Labs Ltd.

Not yet recruiting

Evaluation of Psilocybin-Assisted Psychotherapy in Treating Severe Depression in Patients With PTSD (SUMMIT-90)

Depression | Post-traumatic Stress Disorder
Novartis Pharmaceuticals

Recruiting

Secukinumab Drug Survival, Effectiveness and Tolerability in Pediatric Patients With Psoriasis (SPARROW)

Moderate-to-severe Plaque Psoriasis

Russian Federation
Jiangsu Gensciences lnc.

Recruiting

Phase 3 Clinical Project of Pegylated Recombinant Human Coagulation Factor VIII-Fc Fusion Protein

Severe Hemophilia A

China
Jiangsu Gensciences lnc.

Not yet recruiting

Study of Efficacy and Safety of FRSW107 in Pediatric Patients With Severe Hemophilia A

Severe Hemophilia A

China
Genentech, Inc.

Recruiting

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Vixarelimab in Participants With Moderate to Severe Ulcerative Colitis (UC)

Ulcerative Colitis

United States, Poland
Nektar Therapeutics

Recruiting

A Phase 2b Study to Evaluate Rezpegaldesleukin (Rezpeg) in the Treatment of Adult Patients With Moderate-to-Severe Atopic Dermatitis (REZOLVE-AD)

Moderate to Severe Atopic Dermatitis

Spain, Czechia, United States, Australia, Croatia, Bulgaria, Poland, Canada, Germany, Hungary
P+F Products + Features USA Inc.
P+F Products + Features GmbH; Meditrial USA Inc.

Not yet recruiting

TRIcvalve biCAVal Valve System for Severe Tricuspid Regurgitation (TRICAV) (TRICAV)

Tricuspid Regurgitation | Tricuspid Valve Disease

United States
Guangzhou 8th People's Hospital

Recruiting

Risk Identification Factors for Pulmonary Function Impairment in AIDS Patients Recovered From Severe Pneumonia

Pneumonia | AIDS

China

Search clinical trials for: Severe

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