Search clinical trials for: bioavailability

Total 1994 results

Bristol-Myers Squibb

Completed

A Phase 1, Bioavailability Study of Relatlimab in Combination With Nivolumab

Cancer

United States
University of Wisconsin, Madison

Completed

Bioavailability of Aronia Berry Polyphenols

Polyphenols | Metabolism | Gut Health

United States
OrchestratePharma GmbH
VidiLife Clinical Research Associate

Completed

Bioavailability and Tolerability of Fexofenadine Hydrochloride Topical Lotion 1% (ATOFEX-1)

Psoriasis | Eczema | Pruritus | Atopic Dermatitis | Psoriasis Vulgaris | Urticaria | Skin Rash | Urticaria Chronic | Skin Inflammation | Atopic Dermatitis Eczema | Rash | Atopic Rash

Bangladesh
Pfizer

Completed

A Study to Understand How the Study Medicine (PF-07081532) is Processed and Eliminated in Healthy Men

Healthy Participants

Netherlands
Midwest Center for Metabolic and Cardiovascular...
Pharmavite LLC

Completed

Bioavailability of EPA + DHA in a SMEDS Formulation

Bioavailability

United States
Fundació Eurecat
Circe, S.L.

Completed

Oral Bioavailability of Pterostilbene Cocrystal Compared to Its Free Form (BIOPTERO) (BIOPTERO)

Biological Availability

Spain
Chong Kun Dang Pharmaceutical

Completed

A Study to Evaluate the Relative Bioavailability of Formulations of CKD-510 and to Assess the Effect of Food on the CKD-510 Tablet Formulation in Healthy Subjects

Healthy Volunteers

United States
Hoffmann-La Roche

Completed

Bioavailability and Bioequivalence of Two Risdiplam Tablets in Healthy Participants

Muscular Atrophy, Spinal

United States
University of Bonn
University of Hohenheim

Completed

Plasma Appearance of Xanthohumol in Healthy Adults

Plasmakinetics of Xanthohumol

Germany
University College Dublin
Department of Agriculture Food and the Marine

Completed

Innovative Food Structures to Enhance Nutrient Bioavailability (NutriPlus)

Vitamin D Deficiency | Aging Well

Ireland
Journey Medical Corporation
Dr. Reddy's Laboratories Limited

Completed

A Comparative Bioavailability Study of DFD-29 Capsules 40 mg Versus SOLODYN® Tablets 105 mg, Under Fasting & Fed Conditions in Healthy Adult Human Subjects

Pharmacokinetics

Canada
Bristol-Myers Squibb

Completed

A Study to Assess Relative Bioavailability of Branebrutinib, From a Tablet Formulation to the Capsule Formulation, the Effect of Food on the Bioavailability of Branebrutinib From a Tablet Formulation, and the Safety and Drug Levels of Branebrutinib From a Tablet Formulation in Healthy Participants

Healthy Volunteers

United States
Factors Group of Nutritional Companies Inc.

Completed

Pharmacological Profile of Different Berberine Formulations, and Effects on Blood Sugar Levels

Pharmacokinetics

Canada
University Hospital Inselspital, Berne

Withdrawn

Pharmacokinetic Study to Investigate the Bioavailability and Tolerability of 3 Oral Formulations of Sodium Thiosulfate (TSTS)

Healthy
NeuroSense Therapeutics Ltd.

Completed

A Multiple-Dose PK Study to Evaluate the Comparative Bioavailability of PrimeC Tablets to Ciprofloxacin Tablets Co-administered With Celecoxib Capsules, in Healthy Adult Subject

Pharmacokinetics

United States
Genentech, Inc.

Completed

Study to Investigate the Absorption, Metabolism, and Excretion of [14C]-GDC-9545 Following a Single Oral Dose (Part 1) and to Evaluate the Absolute and Relative Bioavailability of Oral Capsule Formulations of GDC-9545 (Part 2) in Healthy Female Subjects of Non-Childbearing Potential

Healthy Volunteers

United Kingdom
BeiGene

Completed

Relative Bioavailability of Zanubrutinib Tablets Compared to Capsules and Effects of Food on the Pharmacokinetics of the Tablet in Healthy Adults

Healthy Volunteers

United States
GlaxoSmithKline

Completed

A Study to Evaluate Pharmacokinetic, Safety, Tolerability and Relative Bioavailability of Gepotidacin in Healthy Adult Male and Female Participants

Healthy Volunteers

United States
GlaxoSmithKline

Completed

Comparison of Daprodustat Formulations Produced by Two Methods of Manufacture for Bioequivalence and Dissolution in Healthy Participants

Anaemia

United States
Appalachian State University
Brassica Foundation for Chemoprotection Research

Completed

Broccoli Sulforaphane Bioavailability With Mustard

Sulforaphane Bioavailability

United States
Instituto de Investigacion Nutricional, Peru
University of East Anglia; Quadram Institute Bioscience

Completed

Iron and Zinc Bioavailability From Biofortified Potatoes

Biofortification | Potato

Peru
Acasti Pharma Inc.

Active, not recruiting

Comparative Bioavailability of Betamethasone Oral Solution Metered Spray (GTX-102) in Healthy Subjects

Ataxia Telangiectasia

Canada
Cinclus Pharma AG

Completed

Relative Bioavailability of Linaprazan for the Test Formulation vs. Reference Formulation (BA)

Pharmacokinetics | Bioavailability | Safety

Slovenia
Jiangsu HengRui Medicine Co., Ltd.

Completed

Study of Bioavailability, Pharmacodynamics and Safety of SHR-1209 Administered by Single Subcutaneous Injection at Different Sites in Healthy Volunteers

Hypercholesterolemia and Hyperlipidemia

China
The Affiliated Hospital of Qingdao University

Completed

Bioavailability and Bioequivalence of Ezetimibe Tablets in Healthy Subjects

Hyperlipidemias

China
Daiichi Sankyo, Inc.
Quotient Sciences

Completed

A Study to Determine the Absolute Oral Bioavailability of Quizartinib Using a Radiolabeled Microtracer in Healthy Subjects

Healthy Subjects

United Kingdom
University of Glasgow
British Broadcasting Corporation

Completed

Impact of the Food Matrix on Iodine Bioavailability

Iodine Bioavailability

United Kingdom
Banner Life Sciences LLC

Completed

Comparative Bioavailability of BAFIERTAM™ (Monomethyl Fumarate) and Tecfidera® (Dimethyl Fumarate) in Healthy Subjects

Relapsing Remitting Multiple Sclerosis
Swiss Tropical & Public Health Institute
Drugs for Neglected Diseases; Ifakara Health Institute

Completed

PK, Safety and Tolerability of Single and Multiple Doses of Oxfendazole Tablets (HELP-OFZ)

Filariasis

Tanzania
Pfizer

Completed

Relative Bioavailability Study of Nirmatrelvir/Ritonavir 4 Different Fixed Dose Combination Tablets Relative to the Commercial Tablets in Healthy Participants

Healthy Participants | Biological Availability

United States
Nutrition Institute, Slovenia
Vizera d.o.o.; ADM, Ambulanta družinske medicine, Ljubljana, Slovenia; Adrialab... and other collaborators

Completed

Comparative Single-dose Bioavailability Study of Different CoQ10 Formulations

Bioavailability of Coenzyme Q10

Slovenia
Galderma R&D

Completed

Study to Access the Relative Bioavailability of Subcutaneous Dose of Nemolizumab When Administered Via Auto-Injector Versus Dual-Chamber Syringe

Healthy Volunteers

United States
Edda Sciutto Conde

Completed

Pilot Study to Evaluate Bioavailability of Methylprednisolone Administered Intranasally.

Bioavailability of Methylprednisolone Intranasally | Bioavailability of Methylprednisolone Intravenously | Comparison Intranasally vs Intravenously

Mexico
Genentech, Inc.

Completed

A 3-Part Study to Determine the Relative Bioavailability of Capsule and Tablet Formulations of GDC-0980, the Effect of Food, and the Effect of Rabeprazole on the Pharmacokinetics of the Tablet

Healthy Volunteer

United States
Universidad Nacional Autonoma de Mexico

Completed

Evaluation of the Bioavailability of Dexamethasone in Healthy Subjects

Inflammation | Healthy Subjects | Intravenous Drug Usage | Dexamethasone Administration | Intranasal Administration

Mexico
Vertex Pharmaceuticals Incorporated

Completed

A Study to Evaluate the Relative Bioavailability of a Fixed-dose Combination Tablet of VX-121/Tezacaftor/Deutivacaftor

Cystic Fibrosis

United States
Pfizer

Completed

A Bioequivalence Study Between the Proposed and Current Talazoparib Capsule Formulation and Food Effect Study for the Proposed Talazoparib Capsule Formulation in Participants With Advanced Solid Tumors

Breast Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | NSCLC | Prostate Cancer | Advanced Solid Tumors | Solid Tumors

United States, Australia
Wockhardt

Completed

Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Multiple Ascending Doses of Intravenous WCK 771

Bioavailability

United States
Cerevance Beta, Inc.

Completed

Relative Bioavailability and Food Effect Study of CVN424

Parkinson Disease

United States
scPharmaceuticals, Inc.

Completed

Crossover Study to Compare the Pharmacokinetics and Bioavailability of a Novel Furosemide Regimen Administered Subcutaneously vs. the Same Dose Administered Intravenously in Subjects With Chronic Heart Failure

Heart Failure

United States
Midwest Center for Metabolic and Cardiovascular...
Naturmega

Completed

Bioavailability of EPA/DHA in of Ruby-O and Krill Oil

Bioavailability

United States
Eli Lilly and Company
Loxo Oncology, Inc.

Completed

A Study of Absorption, Metabolism, Excretion, and Absolute Bioavailability of Carbon-14-Labelled [14C] Selpercatinib (LY3527723) in Healthy Male Participants

Healthy

United States
Eisai Limited

Suspended

A Study to Evaluate the Relative Bioavailability of E7386 Following Oral Administration of Targeted Release (TR) Tablets Compared to an E7386 Immediate Release (IR) Tablet in Healthy Adult Participants

Healthy Volunteers

United Kingdom
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Bioavailability Study of SHR1459 on Healthy Chinese Volunteers

Healthy Adult Subjects

China
AstraZeneca
Parexel

Completed

A Study to Assess the Relative Bioavailability and Safety of Different Formulations of AZD4831 in Fasted State in Healthy Volunteers.

Healthy Volunteers

United States
Spanish National Research Council
Andalusian Health Service; Universidad Pablo de Olavide

Completed

Bioavailability of Oleanolic Acid Formulated as Functional Olive Oil (BIO-OLTRAD)

Healthy Subjects | Bioavailability

Spain
Cingulate Therapeutics

Completed

Fed-Fast Crossover Study to Assess the Effect of Food With CTx-1301 in Healthy Subjects (Fed-Fast)

Healthy Volunteers in Fed and Fasted State

United States
Amgen

Completed

A Study to Evaluate the Relative Bioavailability of AMG 510 Administered as Tablets and as a Water Dispersion in Healthy Participants

Healthy Participants

United States
Shire
Takeda Development Center Americas, Inc.

Completed

A Study to Evaluate the Bioavailability of Teduglutide Administered Subcutaneously by Syringe Injection Versus Pen Injector in Healthy Adult Participants

Healthy Volunteers

United States
AstraZeneca
Quotient Sciences

Completed

A Randomised, Open-Label Study to Evaluate the Relative and Absolute Bioavailability of Cotadutide in Healthy Subjects

Chronic Kidney Disease | Type 2 Diabetes Mellitus (T2DM) | Non-alcoholic Steatohepatitis

United Kingdom

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