Search clinical trials for: locally advanced rectal cancer

Total 96270 results

Sixth Affiliated Hospital, Sun Yat-sen University
Sir Run Run Shaw Hospital; The Third Affiliated Hospital of Kunming Medical...

Completed

RadioPathomics Artificial Intelligence Model to Predict nCRT Response in Locally Advanced Rectal Cancer (RPAI-pCR)

Rectal Cancer

China
Grupo Espanol Multidisciplinario del Cancer Digestivo
Pivotal S.L.

Completed

Induction FOLFOX With or Without Aflibercept Followed by Chemoradiation in High Risk Locally Advanced Rectal Cancer (RIA)

Rectal Cancer
Yonsei University

Active, not recruiting

Rectal Cancer, Adjuvant Chemotherapy, FOLFOX(5-fluorouracil/Leucovorin/Oxaliplatin), Total Mesorectal Excision

Locally Advanced Rectal Cancer

Korea, Republic of
Sun Yat-sen University

Completed

Neoadjuvant FOLFOXIRI Chemotherapy Alone for Locally Advanced Rectal Cancer (FORTUNE)

Rectal Cancer

China
Fondazione Policlinico Universitario Agostino Gemelli...
Viewray Inc.

Unknown

THeragnostic Utilities for Neoplastic DisEases of the Rectum by MRI Guided Radiotherapy (THUNDER2)

Locally Advanced Rectal Cancer | Pathological Complete Response | Neoadjuvant Chemoradiotherapy

Italy
Amany sayed Abass

Unknown

Role of Neoadjuvent Radiotherapy in Locally Advanced Cancer Rectum

Rectal Adenocarcinoma

Egypt
Blokhin's Russian Cancer Research Center

Enrolling by invitation

Induction and Consolidation Chemotherapy in Patients With Locally Advanced CRM-positive Rectal Cancer (RuCorT-03)

Rectal Cancer | Rectum Carcinoma | Rectal Neoplasms Malignant

Russian Federation
Hospital Clinic of Barcelona
Hospital Son Espases; Hospital del Mar; Hospital Universitario La Fe; Instituto... and other collaborators

Unknown

Interval Between Neoadjuvant Therapy and Surgery in the Treatment of Locally Advanced Rectal Cancer (CRONOS) (CRONOS)

Rectal Cancer | Neoadjuvant Therapy

Spain
National Cancer Institute, Naples

Completed

Bevacizumab With Pelvic Radiotherapy And Primary Chemotherapy in Patients With Poor-Risk Rectal Cancer (BRANCH)

Rectal Cancer
AIPING ZHOU

Completed

Neoadjuvant Triplet Chemotherapy Regimen in Patients With Locally Advanced Rectal Cancer

Locally Advanced Rectal Cancer

China
Institute of Oncology Ljubljana

Completed

Total Neoadjuvant Therapy Versus Standard Therapy of Locally Advanced Rectal Cancer With High Risk Factors for Failure

Rectal Cancer
Instituto Nacional de Cancer, Brazil

Unknown

Short-course Radiotherapy With Induction and Consolidation Chemotherapy in Patients With Locally Advanced Rectal Cancer (SHORT-ICAR)

Rectal Cancer | Total Neoadjuvant Treatment

Brazil
Instituto Nacional de Cancer, Brazil

Terminated

Induction Chemotherapy Plus Chemoradiotherapy With or Without Aspirin in High Risk Rectal Cancer (ICAR)

Chemoradiation | Rectal Cancer, Adenocarcinoma | Locally Advanced Malignant Neoplasm

Brazil
Santo Spirito Hospital, Italy

Unknown

Surgery for Locally Advanced Colon Cancer: is it Worth it? A Multicenter Retrospective Analysis. (LACC)

Malignant Neoplasm of Large Intestine TNM Staging Primary Tumor (T) T4
Wuhan Union Hospital, China

Active, not recruiting

Preoperative Short Course Radiotherapy With Chemotherapy and Camerelizumab in Locally Advanced Rectal Cancer

Rectal Cancer | Radiotherapy | Immunotherapy

China
UNC Lineberger Comprehensive Cancer Center
Cerulean Pharma Inc.

Terminated

Neoadjuvant Chemoradiotherapy With CRLX-101 and Capecitabine for Rectal Cancer

Rectal Cancer

United States
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Radiation Therapy Plus Chemotherapy Followed by Surgery in Treating Patients With Locally Advanced Cancer of the Rectum

Colorectal Cancer

United States, Canada
Yale University

Completed

Pilot Trial of KD018 With Neo-Adjuvant Concurrent Chemo-Radiation Therapy in Patients With Locally Advanced Rectal Cancer

Rectal Cancer

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...

Completed

Study of High-Dose-Rate Endorectal Brachytherapy (HDRBT) in the Treatment of Locally Advanced Low Rectal Cancer (HDRBT)

Rectal Cancer

United States
Peking University Cancer Hospital & Institute

Unknown

Total Neoadjuvant Treatment Plus SHR1210 for High-risk Rectal Cancer and Biomarker Screening Base on Neoantigen

Rectal Cancer

China
Centre Georges Francois Leclerc

Completed

Preoperative Chemo-radiation With IG-IMRT Dose Escalation for Locally Advanced Rectal Cancers (RADICAL)

Advanced Rectal Cancers

France
Fudan University

Unknown

The Combination of Immunotherapy and Neoadjuvant Chemoradiotherapy in MSI-H Locally Advanced Rectal Cancer

Locally Advanced Rectal Cancer

China
Fudan University

Unknown

The Combination of Immunotherapy and Neoadjuvant Chemoradiotherapy in MSS Locally Advanced Rectal Cancer

Locally Advanced Rectal Cancer

China
Fudan University

Unknown

A Study of Chinese Herbal Compound Dendrobium Huoshanense Granules in NCRT for Patients With Locally Advanced Rectal Cancer

Locally Advanced Rectal Cancer

China
Ziqiang Wang,MD

Unknown

Predicting Locally Advanced Rectal Cancer Response to NCT and NCRT With MRI

MRI | Rectal Cancer

China
Sun Yat-sen University

Unknown

FOLFOX6 Totally Neoadjuvant Chemoradiation Therapy in Locally Advanced Rectal Cancer: A Real World Study (FOTAC)

Rectal Cancer

China
Kaohsiung Medical University Chung-Ho Memorial...

Unknown

The Auxiliary Effects of Fucoidan for Locally Advanced Rectal Cancer Patients

To Observe Whether the Fucoidan Can Improve the Quality of Life of the Such Patients Receiving the Neoadjuvant CCRT

Taiwan
Abramson Cancer Center of the University of Pennsylvania
Bristol-Myers Squibb; Roche Pharma AG

Terminated

Capecitabine,Oxaliplatin & Erbitux Given Throughout Multi-Modal Therapy for Locally Advanced Rectal Adenocarcinoma

Rectal Cancer
Memorial Sloan Kettering Cancer Center

Withdrawn

Study Using Fluorine-18-Labeled Fluoro-Misonidazole Positron Emission Tomography to Detect Hypoxia in Locally Advanced (T3-T4 and./or N1)Primary Rectal Cancer Patients

Colorectal Cancer

United States
Samsung Medical Center

Unknown

Capecitabine Plus Simvastatin in Locally Advanced Rectal Cancer Patients

Adenocarcinoma of Rectum

Korea, Republic of
Lund University Hospital
Merck Sharp & Dohme LLC

Completed

Phase I Study of Cetuximab in Combination With 5-fluoruracil, Mitomycin C and Radiotherapy in Patients With Anal Cancer Stage T2 (>4 cm) - T4 N0-3 M0 or Any T N2-3 M0 (NOAC8)

Locally Advanced Cancer in the Anal Region

Sweden, Norway
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Neoadjuvant Chemoradiotherapy and Adjuvant Chemotherapy in Treating Patients Who Are Undergoing Surgical Resection for Locally Advanced Rectal Cancer

Colorectal Cancer

United States
Sixth Affiliated Hospital, Sun Yat-sen University
Sir Run Run Shaw Hospital; The Third Affiliated Hospital of Kunming Medical...

Unknown

Radiomics-based Artificial Intelligence System to Predict Neoadjuvant Treatment Response in Rectal Cancer (MRAI-pCR)

Rectal Cancer

China
Sixth Affiliated Hospital, Sun Yat-sen University
Sir Run Run Shaw Hospital; The Third Affiliated Hospital of Kunming Medical...

Unknown

RadioPathomics Artificial Intelligence Model to Predict Tumor Regression Grading in Locally Advanced Rectal Cancer (RPAI-TRG)

Rectal Cancer

China
UNICANCER

Terminated

Radiation Therapy, Cisplatin, Fluorouracil, and Cetuximab in Treating Patients With Locally Advanced Anal Cancer

Anal Cancer

France
UNICANCER

Terminated

Radiation Therapy, Chemotherapy, and Cetuximab Followed by Surgery, Chemotherapy, and Cetuximab in Treating Patients With Locally Advanced or Metastatic Rectal Cancer That Can Be Removed by Surgery

Colorectal Cancer

France
First Affiliated Hospital of Zhejiang University

Unknown

Neoadjuvant mFOLFOXIRI Chemotherapy Alone for Extramural Vascular Invasion Positive Locally Advanced Rectal Cancer

Locally Advanced Rectal Cancer

China
Samsung Medical Center

Terminated

Efficacy of NeoThermo-Radio-chemotherapy for LA Rectal Cancer Before Laparoscopic TME: Prospective Phase II Trial (NEOTREAT)

Locally Advanced Rectal Cancer

Korea, Republic of
UMC Utrecht
Maastro Clinic, The Netherlands

Unknown

RECTAL BOOST Study (RECTAL BOOST)

Rectal Cancer

Netherlands
National Cancer Institute (NCI)

Completed

Akt Inhibitor MK2206 in Treating Patients With Previously Treated Colon or Rectal Cancer That is Metastatic or Locally Advanced and Cannot Be Removed by Surgery

Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Recurrent Colon Carcinoma | Recurrent Rectal Carcinoma | Stage IIIA Colon Cancer | Stage IIIB Colon Cancer | Stage IIIC Colon Cancer | Stage IVA Colon Cancer | Stage IVA Rectal Cancer | Stage IVB Colon Cancer | Stage IVB Rectal... and other conditions

United States
Gruppo Oncologico del Nord-Ovest

Unknown

Cetuximab + Avelumab or Avelumab Alone for Unresectable, Locally Advanced or Metastatic Squamous Cell Anal Carcinoma (SCCAC) Progressed After at Least One Line of Systemic Treatment (CARACAS) (CARACAS)

Squamous Cell Anal Carcinoma

Italy
Universitaire Ziekenhuizen KU Leuven

Completed

Neoadjuvant Bevacizumab, Capecitabine and Radiation Therapy With or Without Oxaliplatin Locally Advanced Rectal Cancer (AXEBEAM)

Locally Advanced Rectal Cancer

Belgium
Grupo de Investigación Clínica en Oncología Radioterapia

Unknown

Dose-escalation Trial of Preoperative Radiotherapy and Concurrent Chemotherapy in Locally Advanced Rectal Cancer

Locally Advanced Rectal Cancer

Spain
Swiss Group for Clinical Cancer Research

Completed

External-Beam Radiation Therapy, Capecitabine, and Sorafenib in Treating Patients With Locally Advanced Rectal Cancer

Colorectal Cancer

Switzerland, Hungary
National Cancer Institute (NCI)

Completed

Bevacizumab, Radiation Therapy, and Combination Chemotherapy in Treating Patients Who Are Undergoing Surgery for Locally Advanced Nonmetastatic Rectal Cancer

Rectal Adenocarcinoma | Stage III Rectal Cancer AJCC v7 | Stage II Rectal Cancer AJCC v7

United States
Sun Ying-Shi

Completed

Predicting Pathological Complete Response of Rectal Cancer With Magnetic Resonance(MR) Radiomics

Locally Advanced Rectal Cancer

China
Fudan University

Unknown

UGT1A1 Combined With Pharmacokinetics of SN-38 in CPT-11-based CRT in Patients With Advanced Rectal Cancer

Locally Advanced Rectal Cancer

China
Zealand University Hospital
Rigshospitalet, Denmark; Herlev Hospital

Unknown

Endoscopic Assisted Electrochemotherapy in Addition to Neoadjuvant Treatment of Locally Advanced Rectal Cancer (nECT)

Neoadjuvant Therapy | Locally Advanced Rectal Cancer | Electrochemotherapy | Down Staging

Denmark
Fudan University

Unknown

Radiation-protection Effect of Amifostine in Locally Advanced Rectal Cancer

Locally Advanced Rectal Cancer

China
Dana-Farber Cancer Institute
Bristol-Myers Squibb; Massachusetts General Hospital; Beth Israel Deaconess Medical... and other collaborators

Terminated

Cetuximab, 5-FU and Radiation as Neoadjuvant Therapy for Patients With Locally Advanced Rectal Cancer

Rectal Cancer

United States

3

Subscribe