Search clinical trials for: phase 2a

Total 19263 results

AstraZeneca

Completed

Study in Healthy Volunteers to Investigate the Effects of Rifampin on the Pharmacokinetics of NKTR-118

Drug Induced Constipation

United States
Green Cross Corporation

Completed

A Phase I/IIa Study of GC3110A (Quadrivalent Influenza Vaccine)

Influenza

Korea, Republic of
Vertex Pharmaceuticals Incorporated
Tibotec Pharmaceutical Limited

Completed

A Phase 3 Study of Telaprevir in Combination With Pegasys® and Copegus® in Treatment-Naive Subjects With Genotype 1 Hepatitis C Virus (HCV)

Hepatitis C

Australia, Canada, France, Italy, Poland, United Kingdom, Germany, United States, Spain, Israel, Argentina, Puerto Rico, Austria
Hospices Civils de Lyon
Novartis

Unknown

Nilotinib ± Peg-IFN for First Line Chronic Phase CML Patients (PETALs)

Chronic Myeloid Leukemia

France
Vertex Pharmaceuticals Incorporated

Completed

Phase 2 Study of VX-950, Pegasys® With and Without Copegus® in Hepatitis C

Chronic Hepatitis C

Austria, France, Germany, United Kingdom
Vertex Pharmaceuticals Incorporated

Completed

Phase 2 Study of VX-950, Pegasys®, and Copegus® in Hepatitis C

Chronic Hepatitis C

United States, Puerto Rico
Xenon Pharmaceuticals Inc.

Completed

Phase 2a, Exploratory Study to Evaluate the Safety, Efficacy, Tolerability and Pharmacokinetics of XPF-002 in Patients With Primary/Inherited Erythromelalgia

Inherited Erythromelalgia | Primary Erythromelalgia

United States
MedImmune LLC

Terminated

A Phase 2A Study to Evaluate the Safety and Effect on Exercise Challenge Testing of MEDI-528 in Adults With Asthma

Asthma

United States, Canada
Ironwood Pharmaceuticals, Inc.

Terminated

Phase 2a Study of IW-9179 to Treat Functional Dyspepsia

Dyspepsia | Functional Gastrointestinal Disorders

Belgium, Netherlands
HanAll BioPharma Co., Ltd.

Completed

A Phase 1b/2a, Open-label,Randomized, Safety, Tolerability, Dose Finding, PK/PD, and Preliminary Efficacy Study of SC Hanferon™ in Combination With Ribavirin in Treatment-naïve Subjects With Genotype 1 Hepatitis C

Chronic Hepatitis C Infection | Genotype 1

United States
Janssen Pharmaceutical K.K.

Completed

A Phase III Study of TMC435 in Genotype 1, Hepatitis C-infected Participants Who Failed to Respond to Previous IFN-based Therapy

Hepatitis C, Chronic

Japan
Janssen Pharmaceutical K.K.

Completed

A Phase III Study of TMC435 in Treatment-naive, Genotype 1, Hepatitis C-infected Patients

Hepatitis C, Chronic

Japan
Tibotec BVBA

Completed

A Phase 2a Study to Evaluate Viral Kinetics and Safety of Telaprevir in Participants With Genotype 2 or 3 Hepatitis C Infection

Hepatitis C, Chronic

France, United Kingdom, Sweden
PhaseBio Pharmaceuticals Inc.

Completed

Phase 1/2a, Randomized, Double-Blind, Placebo-Controlled, Study to Assess Safety, Tolerability, PK and PD Response of PB1023 Injection Following Single and Multiple SQ Doses in Adults With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

United States
Supernus Pharmaceuticals, Inc.

Completed

Phase 2a Study of Safety and Tolerability of SPN-810 in Children With ADHD and Persistent Serious Conduct Problems

Conduct Disorder | Attention Deficit Disorder With Hyperactivity

United States
Pfizer

Completed

A Trial In Diabetic Patients To Assess Effect Of CE-326,597 On Glucose Control And Body Weight

Weight Management | Treatment Of Obesity

Canada, United States, Bulgaria, Spain, Mexico, India, Puerto Rico
Cytheris SA

Unknown

Dose Escalation of Interleukin-1 (IL-7) Added on Antiviral Treatment and Vaccination in HBeAg-negative Chronic Hepatitis B Virus (HBV) Infected Patients (CONVERT)

Chronic Hepatitis B

France, Italy
Cytheris SA

Unknown

Dose Escalation Study of Interleukin-7 (IL-7) and Bitherapy in HCV Genotype 1 or 4 Patients Resistant to Bitherapy Alone (Eclipse 2)

Hepatitis C

France, Switzerland, Italy
Cytheris SA

Unknown

Dose Escalation Study of Interleukin-7 (IL-7) and Bitherapy in Asiatic HCV Patients Resistant to Bitherapy (ECLIPSE 3)

Hepatitis C

Taiwan
Capstone Therapeutics

Completed

A Phase 2a Study to Evaluate the Safety and Efficacy of AZX100 in Trocar Sites of Arthroscopic Shoulder Surgery Patients

Scar Prevention | Scar Reduction

United States
AstraZeneca

Completed

Study in Healthy Males to Assess Bioavailability of Single Fostamatinib With iv Micro Tracer Dose

Healthy

United Kingdom
AVEO Pharmaceuticals, Inc.

Completed

A Phase 1b/2a, Open-Label, Multi-Center Study of Tivozanib (AV-951) in Combination With Paclitaxel in Subjects With Advanced or Metastatic Breast Cancer

Metastatic Breast Cancer

United States, Germany
MedImmune LLC

Terminated

A Phase 1/2A Study to Evaluate the Safety, Immunogenicity, and Shedding of MEDI-560 in Infants 1 to < 12 Months of Age

Healthy

United States
AstraZeneca

Completed

To Assess the Safety, Tolerability and Pharmacokinetics of AZD2820 After Single Ascending Doses

Healthy

United Kingdom
Abbott Products
Quintiles, Inc.

Terminated

A Phase 2a Dose Escalation Study With SLV334 in Patients With Traumatic Brain Injury.

Traumatic Brain Injury

United States, Israel, Italy, Spain
Telik

Completed

Phase 1-2a Dose-Ranging Study of TLK286 in Combination With Docetaxel in Platinum-Resistant Non-Small Cell Lung Cancer

Carcinoma, Non-small-cell Lung

United States
ActoGeniX N.V.

Completed

A Phase 2a Study to Evaluate the Safety, Tolerability, Pharmacodynamics and Efficacy of AG011 in Ulcerative Colitis

Moderately Active Ulcerative Colitis

Canada, Netherlands, Sweden, Belgium
London Health Sciences Centre

Suspended

Trial Comparing the Safety of Two Different Intravenous Iron Formulations

Iron Deficiency Anemia | Perioperative Blood Conservation

Canada
Hospital Carlos III, Madrid

Unknown

Phase IV Study to Evaluate the Efficacy/Safety to Extend Treatment and High Dose of Ribavirin in co-Infected Patients (PERICO)

Chronic Hepatitis C

Spain
Aerovance, Inc.

Completed

A Phase 2a Study to Investigate the Effects of Repeated Administration of AeroDerm in Subjects With Atopic Eczema

Atopic Eczema

United Kingdom
National Taiwan University Hospital

Completed

Interferon Treatment for Patients With Chronic Hepatitis C and End Stage Renal Disease

End Stage Renal Disease | Chronic Hepatitis C

Taiwan
National Cancer Institute (NCI)

Completed

A Phase II Trial of All-Trans-Retinoic Acid in Combination With Interferon-Alpha 2a in Children With Recurrent Neuroblastoma or Wilms' Tumor

Neuroblastoma | Nephroblastoma

United States
National Cancer Institute (NCI)

Completed

A Phase II Study of 5-Fluorouracil Administered as a One Hour Infusion in Combination With Calcium Leucovorin and Interferon Alpha-2A in Advanced Colorectal Cancer

Colorectal Neoplasms

United States
DiObex

Completed

A Phase 1/2a Study of the 2S,4R Enantiomer of Ketoconazole in Subjects With Type 2 Diabetes Mellitus

Type 2 Diabetes

United States
Medivation, Inc.
Huntington Study Group

Completed

Safety Study of the Novel Drug Dimebon to Treat Patients With Huntington's Disease

Huntington's Disease

United States
Vertex Pharmaceuticals Incorporated

Completed

Phase 2 Study of VX-950, Pegasys and Copegus in Hepatitis C

Hepatitis C

United States, Puerto Rico
Manhattan Pharmaceuticals

Unknown

Phase 2a Randomized, Double-Blind Study of Oleoyl-Estrone in Male Morbidly Obese Adults

Obesity

United States
Hospices Civils de Lyon

Unknown

AFR10 - Combination Therapy of Imatinib Mesylate (IM) + Alpha-2A Interferon for Chronic Phase CML Patients Resistant or Refractory to IM Used as Single Therapy for at Least One Year

Chronic Myeloid Leukemia

France
Manhattan Pharmaceuticals

Unknown

Phase 2a Obesity Study of Oral Doses of Oleoyl-Estrone (MP-101)

Obesity

United States, Switzerland
Peking University Third Hospital
Jilin Provincial Tumor Hospital; Affiliated Hospital of Hebei University; Hebei...

Not yet recruiting

Nab-Paclitaxel Plus Cisplatin With Concurrent Radiotherapy for Patients With Locally Advanced Cervical Cancer: A Multicentre, Single-arm, Phase II Trial.

Cervical Cancer
Institute of Hematology & Blood Diseases Hospital...

Not yet recruiting

Phase II Study of Post-Transplant Low-Dose Inotuzumab Ozogamicin to Prevent Relapse of Acute Lymphoblastic Leukemia

Acute Lymphoid Leukemia

China
Innolake Biopharm

Not yet recruiting

Phase I/II Study of the ILB-3101 in Patients With Advanced Solid Tumors

Advanced Solid Tumor
Henan Cancer Hospital

Not yet recruiting

This is a Phase II, Open-label, Multicentre Study of Zanubrutinib-containing Regimens in Patients With Newly Diagnosed Mantle Cell Lymphoma

Lymphoma, Non-Hodgkin | Lymphoma, Mantle-Cell
Aldeyra Therapeutics, Inc.

Recruiting

A Phase 3 Clinical Trial to Assess the Efficacy and Safety of Subjects With Dry Eye Disease

Dry Eye Disease

United States
Ascentage Pharma Group Inc.

Not yet recruiting

A Phase 3 Registrational Study of Olverembatinib (HQP1351) in Patients With CML (POLARIS-2)

Chronic Myeloid Leukemia | CML | CML, Chronic Phase

United States
Endeavor Biomedicines, Inc.

Not yet recruiting

A Phase 2 Trial of ENV-101 in Patients With Lung Fibrosis (WHISTLE-PF Trial)

Idiopathic Pulmonary Fibrosis | Progressive Fibrosing Interstitial Lung Disease | Progressive Pulmonary Fibrosis

United States, Switzerland, Canada, Australia, Austria, United Kingdom, Malaysia, Mexico, Germany, Ireland, Korea, Republic of
BeiGene

Not yet recruiting

Phase 1 First-in-Human Study of BGB-C354 Alone and in Combination With Tislelizumab in Participants With Advanced Solid Tumors

Advanced Solid Tumor
Merit Medical Systems, Inc.

Not yet recruiting

Observational Study of the Merit HeRO® Graft and Super HeRO® in Patients on Hemodialysis (PReSeRVE-HD)

End Stage Renal Disease | Hemodialysis Access Failure
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

A Single-arm Phase II Clinical Study of the Efficacy and Safety of Camrelizumab Combined With GEMOX for Unresectable GBCs

Unresectable Gallbladder Cancer

China
Jinghui Wang

Recruiting

A Prospective, Single-arm, Phase II Clinical Trial to Evaluate the Efficacy and Safety of Tafolecimab and Sintilimab Combined With Chemotherapy in Patients With Advanced or Metastatic Driver Gene-negative Non-small Cell Lung Cancer After Failure of First-line Immunotherapy.

Lung Cancer

China

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