Search clinical trials for: single dose,

Total 22449 results

Biruni University

Recruiting

High-dose, Short-term Steroid and Low-dose Long-term Steroid Use in ARDS Caused by COVID-19

Short-term (3 Days) High-dose (1000 mg) Systemic Methylprednisolone

Turkey
SNLD, Ltd.

Recruiting

A Phase I Study of TRN501 in Healthy Volunteers

Parkinson Disease

Japan
Pulmongene Ltd.

Completed

A First in Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Immunogenicity of PMG1015

Idiopathic Pulmonary Fibrosis

Australia
Innovent Biologics (Suzhou) Co. Ltd.

Completed

A Study to Investigate the Pharmacokinetic/Pharmacodynamic Characteristics of IBI128(A New Xanthine Oxidase Inhibitor)

Gout Arthritis

China
Pennington Biomedical Research Center
National Center for Complementary and Integrative Health (NCCIH); Office of...

Completed

Evaluation of Soy-protein Russian Tarragon (Artemisia Dracunculus L.) (RT2)

Diabetes Prevention

United States
Harvard School of Public Health (HSPH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Dietary Biomarkers Intervention Core

Diet, Healthy | Biological Markers | Nutrition, Healthy | Metabolomics

United States
Meissa Vaccines, Inc.

Recruiting

Safety and Immunogenicity of an Intranasal RSV Vaccine Expressing SARS-CoV-2 Spike Protein (COVID-19 Vaccine) in Adults

Covid19

United States
Helixmith Co., Ltd.

Completed

Safety and Efficacy Study Using Gene Therapy for Critical Limb Ischemia

Critical Limb Ischemia

United States, Korea, Republic of
Unity Health Toronto

Completed

Renal Function and Pharmacogenetics in Renal Transplant Recipients Converted From Tac BID to Tac OD

Real Function Post Conversion From Prograf to Advagraf | Examin Ethnicity and Pharmacogenetics of the Cohort Requiring Dose Adjustment Post-conversion

Canada
Bioverativ, a Sanofi company

Completed

A Safety, Tolerability, and Pharmacokinetics Study of a Single Intravenous Injection of Recombinant Coagulation Factor VIII Fc - Von Willebrand Factor - XTEN Fusion Protein (rFVIIIFc-VWF-XTEN) (BIVV001) in Previously Treated Adults With Severe Hemophilia A (EXTEN-A)

Hemophilia A

United States, Japan
Medy-Tox

Completed

MT10109L in the Long-term, Open-label Treatment of Glabellar Lines (GL) and Lateral Canthal Lines (LCL)

Lateral Canthal Lines | Glabellar Lines

United States, Russian Federation, Germany, Canada, Belgium, United Kingdom
Assistance Publique - Hôpitaux de Paris
Ministry of Health, France

Completed

TOward the Lowest Effective DOse of Abatacept or Tocilizumab (TOLEDO)

Rheumatoid Arthritis

France
Cork University Hospital

Completed

Minimum Effective Intrathecal Dose of Local Anaesthetic With Fentanyl for Fractured Neck of Femur(Dose Finding Study).

Minimum Effective Dose of Local Anaesthetic With Fentanyl

Ireland
Masaryk Memorial Cancer Institute

Recruiting

Optimization of Fractionation Schedules of Heel Spur Radiotherapy Prospective Randomized Open-label Trial

Heel Spur

Czechia
BeiGene

Recruiting

Study of BGB-A425 and LBL-007 in Combination With Tislelizumab in Advanced Solid Tumors

Locally Advanced or Metastatic Solid Tumors for Phase 1,Dose Escalation and Phase 2 Safety Lead-in, HNSCC, NSCLC and RCC Participants for Phase 2

Australia, Spain, France, Italy, Korea, Republic of, Poland
Basilea Pharmaceutica

Completed

Study to Assess Safety, Tolerability and Pharmacokinetics of APX001 Administered by Intravenous Infusion to Healthy Subjects

Fungal Infection

Netherlands
Sarepta Therapeutics, Inc.
United States Department of Defense

Withdrawn

A Study to Assess the Safety, Tolerability and Pharmacokinetics of AVI-7537 in Healthy Adult Volunteers

Ebola Hemorrhagic Fever

United States
Galecto Biotech AB

Completed

A First in Human Study to Evaluate the Safety, Tolerability and PK of GB1211 in Healthy Subjects

Safety and Tolerability

United Kingdom
General Hospital of Ningxia Medical University

Completed

The Effects of Spinal Anesthesia on ED50 and BIS50 of Etomidate for the Loss of Consciousness (LOC)

Dose-Response Relationship, Drug

China
LG Life Sciences

Completed

Efficacy and Safety Study of Sr-hGH in Comparison With Daily hGH in ISS Patients

Establishing Dose of Sr-hGH in ISS Patients

Korea, Republic of
Novo Nordisk A/S

Completed

A Research Study Looking at the Comparability of 2 Different Forms of Oral Semaglutide in Healthy People

Type 2 Diabetes | Healthy Volunteers

United States, Canada
Centre Hospitalier Universitaire de Nīmes

Recruiting

Concordance Between Ultra-low Dose (ULD) and Standard Dose CT Scans in the Search for Traumatic Brain Injury (ULD-CRANE)

Head Injuries, Closed | Head Injuries, Penetrating

France
Peking Union Medical College Hospital

Recruiting

Moderately Hypofractionated Adaptive Radiotherapy for Cervical Cancer

Cervical Neoplasm | Radiotherapy; Adverse Effect | Adaptive Radiotherapy

China
University Health Network, Toronto
Princess Margaret Hospital, Canada

Active, not recruiting

Tumor TARGET Prostate Cancer

Prostate Cancer

Canada
Meir Medical Center

Completed

Anti-factor Xa Based Venous Thromboembolism Prophylaxis

Dose Adjustment of Enoxaparin in ICU Patients

Israel
Dairy A Day, Inc.

Completed

"Fermented Dairy Beverage on Inflammation/Immune Function in Stressful Exercise" (DAD)

Healthy Subjects

United States
Longeveron Inc.

Completed

Lomecel-B on Vaccine-Specific Antibody- Response in Subjects With Aging Frailty (HERA)

Aging Frailty

United States
Sanofi Pasteur, a Sanofi Company

Completed

Annual Study for Collection of Serum Samples in Children and Older Adults Receiving the 2021-2022 Formulations of Fluzone Quadrivalent Vaccine and Fluzone High-Dose Quadrivalent Vaccine, Respectively

Healthy Volunteers | Influenza Immunization

United States
Chiesi Farmaceutici S.p.A.

Completed

PK of BDP/FF/GB Single-inhaler Triple Therapy in Japanese vs. Caucasians

Chronic Obstructive Pulmonary Disease | Asthma

United Kingdom
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Safety, Tolerability and Effects of Single and Multiple Ascending Doses of ASP1707 in Healthy Male and Pre-menopausal Female Subjects, Including a Comparison of the Effects Under Fasted and Fed Conditions in Healthy Young Male Subjects

Pharmacokinetics of ASP1707 | Pharmacodynamics of ASP1707

France
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Recruiting

Study of HS-10517 in Chinese Adult Participants

COVID-19

China
Pfizer
Medivation, Inc.

Completed

A Study To Evaluate The Abuse Potential Of Single Oral Doses Of Dimebon (Latrepirdine) In Healthy Recreational Polydrug Users

Alzheimer's Disease | Huntington's Disease
Onxeo
Spectrum Pharmaceuticals, Inc

Completed

A Phase I/II Clinical Trial of PXD101 in Combination With Doxorubicin in Patients With Soft Tissue Sarcomas

Dose Escalation: Solid Tumors | MTD: Soft Tissue Sarcomas

Denmark, United Kingdom
Neuraltus Pharmaceuticals, Inc.

Completed

Single-Ascending-Dose Safety/Tolerability of NP001 in Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis

United States
CohBar, Inc.

Completed

A Phase 1a/1b Study of CB4211 in Healthy Non-obese Subjects and Subjects With Nonalcoholic Fatty Liver Disease

Nonalcoholic Fatty Liver Disease

United States
Sanofi Pasteur, a Sanofi Company

Completed

Study of Fluzone® Influenza Virus Vaccine 2011-2012 Formulation (Intramuscular Route) Among Adults

Influenza

United States
Galapagos NV

Completed

A Study to Assess Safety, Tolerability and Pharmacokinetics of GLPG2737 in Healthy Subjects

Healthy

Netherlands
AstraZeneca

Recruiting

A Single and Multiple Ascending Dose Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD2389 in Healthy Participants

Healthy Participants

United States
Kyowa Kirin Co., Ltd.

Completed

A Study of Single and Multiple Doses of KW-6356 in Healthy Subjects

Parkinson's Disease

Japan
Boehringer Ingelheim

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Oral Doses of BI 1181181 in Healthy Male Volunteers

Healthy

Belgium
MedImmune LLC

Completed

A Study to Evaluate Safety and Pharmacodynamic Efficacy of 0382 in Obese Subjects With NAFLD/NASH.

Non-alcoholic Fatty Liver Disease (NAFLD) | Non-alcoholic Steatohepatitis (NASH)

United States, Puerto Rico
Medigene AG

Withdrawn

HA-1H TCR T Cell for Relapsed/Persistent Hematologic Malignancies After Allogeneic Stem Cell Transplantation

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Myeloproliferative Disorders | Multiple Myeloma | Myelofibrosis | Chronic Myeloid Leukemia | Acute Lymphoid Leukemia | Malignant Lymphoma

Netherlands
Gamaleya Research Institute of Epidemiology and...

Completed

Evaluation of the Safety and Immunogenicity of the Recombinant Subunit Vaccine "GamTBvac" Against the Tuberculosis. (GamTBvac)

Tuberculosis

Russian Federation
Janssen Research & Development, LLC

Completed

A Study of Seltorexant (JNJ-42847922) After Single-Dose Administration in Healthy Participants

Healthy

United States
Aronora, Inc.

Completed

Safety and Tolerability Study of Xisomab 3G3 in Healthy Adult Subjects

Thrombosis

United States
Hipra Scientific, S.L.U

Completed

Assessing the Immunogenicity and Safety of a HIPRA's Candidate Booster Vaccination in Adults Fully Vaccinated With Adenovirus Vaccine Against COVID-19.

COVID-19 | SARS-CoV-2 Acute Respiratory Disease

Spain
Biocad

Recruiting

A Trial of the Safety and Efficacy of Single-Dose Administration of ANB-010 in Subjects With Hemophilia A (EDELWEISS)

Hemophilia A

Russian Federation
GlaxoSmithKline

Completed

Phase I Study of GW856553 (Losmapimod)

Acute Coronary Syndrome

Australia
Sinovac Biotech Co., Ltd

Completed

Studies of the Safety and Immunogenicity of a Sabin Inactivated Poliovirus Vaccine

Poliomyelitis

China
Sixth Affiliated Hospital, Sun Yat-sen University

Recruiting

Management of LLN Metastasis in Locally Advanced Rectal Cancer: A Prospective Radiation Dose Escalation Study

Rectal Cancer

China

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