Search clinical trials for: systemic treatment for their metastatic disease

Total 466232 results

Fudan University

Recruiting

Sintilimab Combined With Modified FLOT Regimen in the Treatment of Metastatic Gastric Cancer

Gastric Cancer | Chemotherapy Effect | Immune Checkpoint Inhibitor

China
Shuangyue Liu

Not yet recruiting

Study of Dalpiciclib Combined With Letrozole in the Maintenance Treatment of HR Positive and HER2 Negative Metastatic Breast Cancer After First-line Chemotherapy

Breast Cancer

China
HuiKai Li

Not yet recruiting

Hepatic Artery Infusion of Adebrelimab Combined With Bevacizumab in the Treatment of Advanced Hepatocellular Carcinoma With Failure of Systemic Therapy Combined With Interventional Therapy

Hepatocellular Carcinoma

China
European Organisation for Research and Treatment...
UNICANCER; Spanish Oncology Genito-Urinary Group; Cancer Trials Ireland

Not yet recruiting

Intermittent Androgen Deprivation Therapy in the Era of AR Pathway Inhibitors

Prostate Cancer
Cancer Institute and Hospital, Chinese Academy...

Recruiting

XELOX +Bev +Tislelizumab for First-line Treatment of MSS/pMMR RAS-mutated mCRC

Bevacizumab | Capecitabine | Metastatic Colorectal Cancer (mCRC) | Oxaliplatin | Tislelizumab | First-Line | MSS/pMMR | RAS-mutated

China
Krystal Biotech, Inc.

Recruiting

A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors

Cancer | Carcinoma, Squamous Cell | Carcinoma, Basal Cell | Osteosarcoma | Cutaneous Melanoma | Melanoma Stage IV | Melanoma Stage III

United States
Chinese SLE Treatment And Research Group

Recruiting

Efficacy and Safety for Telitacicept in the Remission Maintenance Treatment of ANCA-associated Vasculitis (TTCAZAREM)

ANCA-associated Vasculitis | Maintenance Therapy

China
Memorial Sloan Kettering Cancer Center
AstraZeneca; Novartis Pharmaceuticals

Recruiting

A Study to Prevent Rash in People Starting Alpelisib for the Treatment of Breast Cancer

Breast Cancer

United States
Recep Tayyip Erdogan University
Turkish Society of Thoracic and Cardio-Vascular Anesthesia and Intensive...

Not yet recruiting

Pressure Recording Analytical Method Parameters and Their Relationship With Hypotension in Hypertensive Patients (PRAM-in-HYPO)

Cardiovascular Diseases | Surgery | Hypotension | Hypotension During Surgery | Hypotension on Induction

Turkey
Chinese SLE Treatment And Research Group
Peking Union Medical College Hospital

Recruiting

Efficacy and Safety for Rituximab Combined With Telitacicept in the Treatment of ANCA-associated Vasculitis (TTCAAVREM)

ANCA Associated Vasculitis

China
Aurinia Pharmaceuticals Inc.
Labcorp Corporation of America Holdings, Inc

Not yet recruiting

Long-Term Voclosporin Treatment in Adolescent Subjects With Lupus Nephritis (VOCAL-EXT)

Adolescent Lupus Nephritis

United States
Sun Yat-sen University

Recruiting

Cetuximab and Envafolimab Plus mFOLFOXIRI as First-line Treatment for RAS/BRAF Wild-type, MSS, Unresectable Left-side Metastatic Colorectal Cancer (CEIL)

Metastatic Colorectal Cancer

China
University of Miami

Recruiting

Discontinuation of Maintenance HER-2 Directed Therapy in Long-Term Survivors of Metastatic HER-2 Positive Breast Cancer (Free-HER)

Stage IV Breast Cancer | HER2-positive Metastatic Breast Cancer

United States
The First Affiliated Hospital with Nanjing Medical...

Recruiting

Comparing a 6-month vs Long-term Course of Rezvilutamide With ADT Plus Chemotherapy in mHSPC

Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)

China
Junjie Peng

Not yet recruiting

A Study to Explore the Third-line Treatment of Fruquintinib Combined With Serplulimab in Advanced Non-isolated Hepatic Metastatic Colorectal Cancer: a Single-center, Phase 2 Study

Colorectal Cancer

China
Peking Union Medical College Hospital
Beijing Tongren Hospital; Southern Medical University

Recruiting

Construction of Diagnosis and Treatment System for Primary Vitreoretinal Lymphoma

Primary Vitreoretinal Lymphoma

China
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Manufacturing of Allogeneic Adipose Tissue-derived Mesenchymal Stromal Cells for Treatment of Severe Systemic Sclerosis (Pre_MSC-AT-SSc)

Systemic Sclerosis | Mesenchymal Stromal Cell
National Cancer Institute (NCI)

Recruiting

Testing the Combination of Two Anticancer Drugs M1774 (Tuvusertib) and Avelumab to Evaluate Their Safety and Effectiveness in Treating Merkel Cell Skin Cancer, MATRiX Trial

Metastatic Merkel Cell Carcinoma | Refractory Merkel Cell Carcinoma | Locally Advanced Merkel Cell Carcinoma | Unresectable Merkel Cell Carcinoma | Clinical Stage III Cutaneous Merkel Cell Carcinoma AJCC v8 | Clinical Stage IV Cutaneous Merkel Cell Carcinoma AJCC v8

United States
Yonsei University

Not yet recruiting

Efficacy of Fexuprazan for Prevention or Control of Gastritis Symptoms in Patients on Treatment With Systemic Steroids

Patients on Treatment With Systemic Steroids

Korea, Republic of
University of Rochester
Varian Medical Systems

Recruiting

This Study is Evaluating a New Radiation Treatment Technique for Patients Who Have Had Prostate Cancer, Undergone Surgery for Cancer, and Then Have Evidence That Their Prostate Cancer Has Returned. (DASBRT-RPC)

Recurrent Prostate Cancer After Surgery

United States
Centre Georges Francois Leclerc

Not yet recruiting

Clinical Trial Evaluating the Safety and Efficacy of Chemoimmunotherapy Plus Short Course of Mek Inhibitor in First Line of Treatment of Metastatic Non Squamous Non Small Cell Lung Adenocarcinoma With PDL1 < 50 %. (IMMUNOMEK)

Non-Small Cell Lung Cancer
Xiangya Hospital of Central South University
Beijing Medical Award Foundation

Not yet recruiting

Comparing Mescaline Sodium Enteric-coated Tablets vs Morte-mescaline in the Treatment of Adult Lupus Nephritis

Lupus Nephritis
Odense University Hospital

Recruiting

Early Initiated Vasopressor Therapy in the Emergency Department (VASOSHOCK)

Shock | Shock, Septic | Hypotension | Hypovolemia | Hypotension and Shock | Hypovolemic Shock | Hypotension Symptomatic | Hypovolemic

Denmark
National Health Research Institutes, Taiwan
China Medical University Hospital; Chang Gung Memorial Hospital; Kaohsiung Medical... and other collaborators

Not yet recruiting

Ramucirumab (Cyramza), Nal-IRI (ONIVYDE) and Trifluridine/Tipiracil (Lonsurf) in Second Line Metastatic Gastric Cancer .

Chemotherapy | Metastatic Gastric Adenocarcinoma | Second Line
Fudan University

Not yet recruiting

An Umbrella Trial Based on Molecular Pathway for Patients With Metastatic TNBC in First-line Treatment (FUTURE-Trop2)

TNBC - Triple-Negative Breast Cancer
GeneScience Pharmaceuticals Co., Ltd.

Not yet recruiting

To Evaluate the Efficacy and Safety of Genalumab for Injection in the Treatment of Active Systemic Juvenile Idiopathic Arthritis.

Active Systemic Juvenile Idiopathic Arthritis

China
AstraZeneca

Recruiting

Determine Effectiveness of Anifrolumab In SYstemic Sclerosis (DAISY) (DAISY)

Systemic Sclerosis | Scleroderma

United States, Italy, Mexico, Hungary, Belgium, Spain, Japan, Poland, Germany, China, India, Korea, Republic of, Vietnam, France, Austria, Israel, Canada, Turkey, Netherlands, United Kingdom, South Africa, Romania
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Trastuzumab Deruxtecan (T-DXd): Tailoring Treatment and Companion Diagnostics (CDx) by Liquid Biopsy (DIAMOND)

Metastatic Breast Cancer

Italy
Chinese SLE Treatment And Research Group
Peking Union Medical College Hospital

Recruiting

Effectiveness of Mycophenolate Mofetil Combined With Tacrolimus for Steroid Tapering in Systemic Lupus Erythematosus

Systemic Lupus Erythematosus | Lupus Nephritis

China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
First Affiliated Hospital of Jinan University; Shenzhen University General...

Recruiting

Pemigatinib Combined With PD-1 Inhibitor in Unresectable or Metastatic Intrahepatic Cholangiocarcinoma

Carcinoma | Digestive System Neoplasms | Intrahepatic Cholangiocarcinoma | First-line Treatment | PD-1 Inhibitor

China
CytoAgents, Inc.
TFS HealthScience

Recruiting

Study of CTO1681 for the Prevention and Treatment of CRS in DLBCL Patients Receiving CAR T-Cell Therapy

Cytokine Release Syndrome

United States
Hoffmann-La Roche
Chugai Pharmaceutical

Recruiting

A Study Evaluating Atezolizumab and Bevacizumab, With or Without Tiragolumab, in Participants With Untreated Locally Advanced or Metastatic Hepatocellular Carcinoma (IMbrave152) (SKYSCRAPER-14)

Carcinoma, Hepatocellular

United States, Canada, Korea, Republic of, Taiwan, China, Puerto Rico, Japan, New Zealand, Belgium, Brazil, Spain, Germany, Poland, Thailand, Singapore, France, Turkey, Italy, United Kingdom, Mexico, Côte D'Ivoire, Hong Kong, Nigeria, South Africa
Guangxi Medical University

Not yet recruiting

Cadonilimab in the Treatment of Recurrent/Metastatic Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma | Immune Checkpoint Inhibitors
Peking Union Medical College

Not yet recruiting

Vedicitumomab Alone or in Combination for the Treatment of Locally Advanced or Metastatic SDC

Salivary Gland Cancer
Summit Therapeutics

Recruiting

Clinical Study of Ivonescimab for First-line Treatment of Metastatic Squamous NSCLC Patients

Non-Small Cell Lung Cancer

United States, Canada
Peking University

Not yet recruiting

Phase II Study to Evaluate the Efficacy and Safety of 177Lu-Dotatate in the First-line Treatment of Patients With Locally Advanced or Metastatic, Somatostatin Receptor-positive G2 or G3 Gastroenteropancreatic Neuroendocrine Tumors

Neuroendocrine Tumors

China
Peking Union Medical College Hospital

Recruiting

The Efficacy and Safety of Penpulimab in the Treatment of Metastatic PPGL Patients Who Fail to Other Systemic Treatment

Pheochromocytoma, Metastatic | Paraganglioma, Malignant | Pheochromocytoma Malignant

China
SOLTI Breast Cancer Research Group
Merck Sharp & Dohme LLC; Pfizer; AstraZeneca; Astellas Pharma Inc; Advanced Accelerator... and other collaborators

Recruiting

Feasibility and Impact of Liquid Biopsy Genomic Profiling on Treatment Patients With Metastatic Prostate Cancer in Spain (SOLTI-2102) (HOPE-PROSTATE)

Metastatic Prostate Cancer

Spain
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

BACTERIUM: Study for a Machine-learning-based Model to Predict Bloodstream Infections (BACTERIUM)

Infection, Bloodstream

Italy
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Bright White Light Therapy in Reducing Cancer-Related Fatigue and Depression in Advanced Prostate Cancer Patients Undergoing Treatment With ADT Combination Therapy

Metastatic Prostate Carcinoma | Stage IV Prostate Cancer AJCC v8 | Prostate Carcinoma | Stage III Prostate Cancer AJCC v8 | Advanced Prostate Carcinoma

United States
Changhai Hospital

Recruiting

Implantation of iodine125-Seeds Combined With Chemotherapy in the Treatment of Metastatic Pancreatic Carcinoma

Metastatic Pancreatic Cancer

China
MedSIR
Daiichi Sankyo

Recruiting

HER3-DXd in Breast Cancer and NSCLC Brain Metastases and Solid Tumor Leptomeningeal Disease (TUXEDO-3)

Metastatic Breast Cancer | Solid Tumor, Adult | Advanced Non-Small Cell Squamous Lung Cancer

Spain, Austria
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Recruiting

Focused Radiation Versus Systemic Therapy for Kidney Cancer Patients With Limited Metastasis, SOAR Study

Metastatic Renal Cell Carcinoma | Stage IV Renal Cell Cancer AJCC v8

United States
Amsterdam UMC, location VUmc

Recruiting

COLLISION RELAPSE Trial

Recurrence | Colorectal Cancer | Surgery | Chemotherapy Effect | Liver Metastases | Liver Metastasis Colon Cancer

Netherlands
Australasian Gastro-Intestinal Trials Group
Cancer Council Victoria; Walter and Eliza Hall Institute of Medical Research

Recruiting

RESOLUTE Trial Aims to Investigate the Value of Adding Local Ablative Treatment to Standard Systemic Treatment for Unresectable Oligometastatic Colorectal Cancer (RESOLUTE)

Colorectal Cancer | Oligometastatic Disease

Australia
Shanghai Pharmaceuticals Holding Co., Ltd

Recruiting

Safety and Efficacy of SPH4336 in Combination With Endocrine Therapy in the Treatment of Locally Advanced or Metastatic Breast Cancer

Locally Advanced or Metastatic Breast Cancer

China
RenJi Hospital
Gracell Biotechnology Shanghai Co., Ltd.

Recruiting

Dual Target CAR-T Cell Treatment for Refractory Systemic Lupus Erythematosus (SLE) Patients

CAR-T Cell Therapy

China
Tianjin Medical University Cancer Institute and...

Recruiting

Cadonilimab in Combination With Ramucirumab for the Treatment of Advanced Hepatocellular Carcinoma That Has Failed at Systemic Therapy

Advanced Hepatocellular Carcinoma That Has Failed at Systemic Therapy

China
Galapagos NV

Recruiting

A Study Evaluating the Effects of GLPG3667 Administered as Oral Treatment in Adult Participants With Active Systemic Lupus Erythematosus (GALACELA)

Systemic Lupus Erythematosus

United States, Spain, Bulgaria, France, Georgia, Germany, Puerto Rico, Argentina, Poland, Hungary, Chile, Peru
Sun Yat-sen University

Recruiting

Gemcitabine and Camrelizumab Plus Apatinib Versus Cisplatin in First-line Treatment of RM-NPC

Nasopharyngeal Carcinoma

China

Search clinical trials for: systemic treatment for their metastatic disease

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