Clinical Trials Sponsored by Grunenthal GmbH

Total 3301 results

Institut für Klinische Krebsforschung IKF GmbH...
Celgene International II S.á.r.l.; Prof. F. Heidel, MH Hannover

Recruiting

Fedratinib in Combination With Nivolumab

Primary Myelofibrosis | Secondary Myelofibrosis

Germany
Saving Patients' Lives Medical B.V.
Radboud University Medical Center; ABX-CRO advanced pharmaceutical services... and other collaborators

Recruiting

Ferumoxtran-10-enhanced MRI in Prostate Cancer Patients

Prostate Cancer | Metastasis | Prostatectomy

Germany, Belgium, Netherlands, Switzerland
Insel Gruppe AG, University Hospital Bern
Swiss National Science Foundation; Mach Gaensslen Foundation; Baxalta Innovations...

Recruiting

Genotype and Phenotype Correlation in Hereditary Thrombotic Thrombocytopenic Purpura (Upshaw-Schulman Syndrome) (TTP registry)

Thrombotic Thrombocytopenic Purpura | Congenital Thrombotic Thrombocytopenic Purpura | Familial Thrombotic Thrombocytopenic Purpura | Thrombotic Thrombocytopenic Purpura, Congenital | Upshaw-Schulman Syndrome

United States, Austria, Czechia, Germany, Japan, Norway, Switzerland
Atrial Fibrillation Network
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company; Deutsches Zentrum für...

Terminated

Non-vitamin K Antagonist Oral Anticoagulants in Patients With Atrial High Rate Episodes (NOAH)

Atrial High Rate Episodes

Austria, Belgium, Bulgaria, Czechia, France, Germany, Greece, Hungary, Italy, Netherlands, Poland, Portugal, Romania, Spain, Sweden, Ukraine, United Kingdom, Denmark
European Association of Urology Research Foundation
Incyte Biosciences International Sàrl; AMS Advanced Medical Services GmbH; High...

Terminated

Safety and Efficacy of Pemigatinib in Patients With High-risk Urothelial Cancer After Radical Surgery (PEGASUS)

Urothelial Cancer

Italy
Buchinger Wilhelmi Development & Holding GmbH
King's College London; University of Geneva, Switzerland; ETH Zurich (Switzerland) and other collaborators

Completed

Oral and Gut Microbiota Changes During Long-term Fasting in Humans (OralFast)

Healthy | Periodontitis

Germany
LinkCare GmbH
Charite University, Berlin, Germany; Abbott; Ruhr University of Bochum; University... and other collaborators

Completed

Fractional FLOw Reserve In Cardiovascular DiseAses (FLORIDA)

Coronary Artery Disease | Acute Coronary Syndrome

Germany
Dr. Kurt Wolff GmbH & Co. KG
Poznan University of Medical Sciences; Wuerzburg University Hospital; Medical...

Completed

Hydroxyapatite-toothpaste and Enamel Caries in the Primary Dentition (ECIPDEN17)

Tooth Demineralization | Tooth Diseases | Tooth Decay | Hydroxyapatite

Poland
Technical University of Munich
Novalung GmbH, Heilbronn, Germany; Studiensekretariat Intensivmedizin; II....

Unknown

Extracorporeal Lung Assist Device in Acute Lung Impairment (EXODUS)

Acute Respiratory Distress Syndrome

Austria, Germany, Hungary, United Kingdom
Medical University of Graz
AIT Austrian Institute of Technology GmbH; Ludwig Boltzmann Institute for translational...

Unknown

Integrated Telemonitoring and Nurse Support Evaluation (INTENSE-HF)

Chronic Heart Failure

Austria
Martin-Luther-Universität Halle-Wittenberg
Gambro Dialysatoren GmbH; KfH Kuratorium für Dialyse und Nierentransplantation...

Completed

High-cutoff Hemodialyzer to Reduce Chronic Inflammation in Hemodialysis Patients (HCO1100)

End Stage Renal Disease

Germany
University Hospital Muenster
Isotope Technologies Munich (ITM) Oncologics; Helmholtz Zentrum München Deutsches...

Recruiting

Radioimmunotherapy With Lu-177 Labeled 6A10 Fab-fragments in Patients With Glioblastoma After Standard Treatment (RIT in GBM)

Glioblastom WHO Grade 4

Germany
Institut für Klinische Krebsforschung IKF GmbH...
Johann Wolfgang Goethe University Hospital, Prof. Dr. med. Trojan

Active, not recruiting

Dose Escalation Study of Cabozantinib for Advanced HCC Patients With Preserved Liver Function

Hepatocellular Carcinoma (HCC) | Second Line Treatment

Germany
Baxalta now part of Shire
Takeda Development Center Americas, Inc.; Baxalta Innovations GmbH, now part...

Active, not recruiting

A Study of BAX 888 in Male Adults With Severe Hemophilia A

Hemophilia A

United States, Spain, Hungary, Italy, Germany, Austria, France
Jena University Hospital
University of Leipzig; Technische Universität Dresden; University of Magdeburg; University of Rostock and other collaborators

Completed

Regional Differences in Human Immunodeficiency Virus (HIV) Testing (HIVRegional)

HIV Seropositivity | CD4+ T Lymphocytopenia

Germany
Pascoe Pharmazeutische Praeparate GmbH
Institut für Empirische Gesundheitsökonomie, Prof. Dr. Dr.med. Reinhard Rychlik...

Completed

Treatment of Patients Suffering From Nervous Restlessness With PASCOFLAIR®

Nervous Restlessness
Technische Universität Dresden
University Hospital Carl Gustav Carus; Cellex Gesellschaft für Zellgewinnung... and other collaborators

Completed

Plerixafor as a Salvage Regimen to Mobilize Allogeneic Stem Cells in Healthy Volunteers (MOBIL1)

Blood Stem Cell Harvest Failure

Germany
Chiesi Italia
Gesellschaft für Therapieforschung mbH

Recruiting

Observational Study on Therapy Pathways of Asthamics Treated With ICS/LABA/LAMA Therapy in a Real-world Setting (TRIMAXIMIZE)

Asthma

Italy
Gesellschaft fur Medizinische Innovation - Hamatologie...
Amgen

Completed

Validation of a Predictive Model of Response to Romiplostim in Patients With IPSS Low or Intermediate-1 Risk MDS and Thrombocytopenia (EUROPE)

Myelodysplastic Syndromes

France, Germany
Udo Sechtem

Withdrawn

Therapeutic Effect of Sildenafil in Patients With Coronary Vasospasm

Coronary Vasospasm

Germany
Matthias Schwab

Terminated

Omeprazole and Reflux Disease - Improvement of Clinical Outcome by Genotype-adjusted Dosing (GERD)

Gastroesophageal Reflux

Germany
Schillerhoehe Hospital
Robert Bosch Gesellschaft für Medizinische Forschung mbH

Terminated

Distinction Between Lung Cancer and Gynecological Cancers by Canine Scent Detection

Breast Cancer | Ovarian Cancer | Lung Cancer

Germany
Orputec
Medical University of Graz; Joanneum Research Forschungsgesellschaft mbH

Terminated

The Influence of Pulse-synchronized Negative Pressure on the Dermal Microcirculation (PSyNeP)

Diabetes | Microcirculation

Austria
Udo Sechtem

Terminated

Cardiotropic Viruses in Cardiac Surgery Patients Without Clinical Evidence of Myocarditis or Myocarditic Sequelae

Myocarditis

Germany
Karolinska Institutet
Karolinska University Hospital; Rigshospitalet, Denmark; University of Bergen; Tel... and other collaborators

Completed

Systems Medicine to Study Necrotizing Soft Tissue Infections (NSTIs). (INFECT)

Soft Tissue Infections | Necrotizing Fasciitis | Necrotizing Soft Tissue Infections

Denmark, Norway, Sweden
Charite University, Berlin, Germany
Prof. Dr. Stefan M. Gold; Prof. Dr. Soyoung Q Park; Dr. Ulrike Grittner; Motognosis...

Recruiting

Dopamine Modulation of Motivation and Motor Function in Major Depression & Inflammation (MOTIVADE)

Depressive Disorder, Major

Germany
Institut fuer anwendungsorientierte Forschung und...
German High-Grade Non-Hodgkin's Lymphoma Study Group; University Hospital Goettingen

Completed

Allo-hNHL (FluBuCy)

Non-Hodgkin's Lymphoma

Germany
University of Erlangen-Nürnberg
Neurological Rehabilitation Center Quellenhof; ZTM Bad Kissingen; Medi train... and other collaborators

Completed

Internet-based Physical Activity Promotion and Exercise Prescription for People With Multiple Sclerosis (Feasibility Study)

Multiple Sclerosis

Germany
University of Erlangen-Nürnberg
Neurological Rehabilitation Center Quellenhof; ZTM Bad Kissingen; Medi train... and other collaborators

Completed

Internet-based Physical Activity Promotion and Exercise Prescription for People With Multiple Sclerosis (ms bewegt)

Multiple Sclerosis

Germany
Dominik Paul Modest
German Research Foundation; Institut für Klinische Krebsforschung IKF GmbH...

Recruiting

Post-resection/Ablation Chemotherapy in Patients With Metastatic Colorectal Cancer (FIRE-9 - PORT / AIO-KRK-0418)

Colorectal Cancer

Germany
North Eastern German Society of Gynaecological...
Clovis Oncology, Inc.; Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus...

Active, not recruiting

Rucaparib MAintenance After Bevacizumab Maintenance Following Carboplatin Based First Line Chemotherapy in Ovarian Cancer Patients (MAMOC)

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cancer | Clear Cell Carcinoma

Germany
Techniker Krankenkasse
Technical University of Munich; Federal Joint Committee; privates Institut für... and other collaborators

Completed

Lifestyle Intervention in Chronic Ischemic Heart Disease and Diabetes (LeIKD)

Diabetes Mellitus, Type 2 | Ischemic Heart Disease Chronic

Germany
Daren K. Heyland
RWTH Aachen University; Queen's University; biosyn Arzneimittel GmbH

Active, not recruiting

SodiUm SeleniTe Adminstration IN Cardiac Surgery (SUSTAIN CSX®-Trial). (SUSTAINCSX)

Heart Disease

Canada, Germany
Fresenius Kabi
EastHORN Clinical Services in CEE; MLM Medical Labs GmbH; ALS Czech Republic,... and other collaborators

Completed

Short-term Metabolic Effects of Ketosteril® Supplemented Low Protein Diet in Pre-dialysis Chronic Kidney Disease (CKD) Patients (CKD)

Renal Insufficiency, Chronic

Czechia
University Hospital Carl Gustav Carus
University of Giessen; GWT-TUD GmbH; Clinical Evaluation Research Unit at Kingston...

Terminated

Fish OIL Optimal dosE Determination Study (FOILED)

Sepsis

Germany
Profil Institut für Stoffwechselforschung GmbH
Icahn School of Medicine at Mount Sinai; Heart and Diabetes Center North-Rhine...

Completed

Effects of Food Advanced Glycation Endproducts on Vascular Function in Diabetes

Type 2 Diabetes Mellitus

Germany
University of Erlangen-Nürnberg Medical School
m&i-Fachklinik Herzogenaurach; m&i Fachklinik Bad Heilbrunn; Carealytix Digital...

Recruiting

Smart and Fit for Kidney Transplantation (S&F4NTx)

Chronic Kidney Disease Requiring Chronic Dialysis

Germany
Nikolaj Frost MD
Roche Pharma AG; Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus...

Recruiting

Pemetrexed-free vs. Pemetrexed-based Immunochemotherapy in Metastatic TTF-1 Negative Lung Adenocarcinoma (ANTELOPE)

Non-Small Cell Lung Cancer Metastatic

Germany
University Hospital, Bonn
German Federal Ministry of Education and Research; Pharmacy of the University... and other collaborators

Recruiting

Fight INflammation to Improve Outcome After Aneurysmal Subarachnoid HEmorRhage (FINISHER)

Aneurysmal Subarachnoid Hemorrhage

Germany
Kantonsspital Winterthur KSW
Krebsforschung Schweiz, Bern, Switzerland; Sponser Sport Food AG; Leitwert GmbH; SNAQ... and other collaborators

Recruiting

Influence of a Home-based Nutrition and Exercise Program on Quality of Life of Palliative Cancer Outpatients

Malnutrition | Cancer, Lung | Cancer, Gastrointestinal

Switzerland, Germany
University Hospital Heidelberg
German Cancer Research Center; Janssen-Cilag International NV; inVentiv Health... and other collaborators

Completed

Bendamustine, Prednisone and Velcade® for First-line Treatment of Patients With Symptomatic Multiple Myeloma (BPV)

Multiple Myeloma

Germany
Perosphere Pharmaceuticals Inc, a wholly owned...
Profil Institut für Stoffwechselforschung GmbH

Withdrawn

Pharmacokinetics of Ultra-Rapid-Acting Insulin Lispro (URAL) in Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus

Germany
Institut fuer anwendungsorientierte Forschung und...
German Federal Ministry of Education and Research; University Medical Center...

Completed

Efficacy and Safety Study to Delay Renal Failure in Children With Alport Syndrome

Renal Insufficiency, Chronic

Germany
R.J. Reynolds Tobacco Company
BioClinica, Inc.; Analytisch-biologisches Forschungslabor GmbH; Pacific Biomarkers and other collaborators

Completed

Cardiovascular Disease Biomarkers in Smokers and Moist Snuff Consumers

Cardiovascular Disease | Cigarette Smoking

United States
University Hospital Heidelberg
Deutsches Krankenhausinstitut; DGPPN; DGKJP; DGPM; Forum für Gesundheitswirtschaft...

Recruiting

Evaluation of the "Platform Model" for Staffing in Psychiatric and Psychosomatic Clinics (EPPIK)

Psychosomatic Medicine

Germany
Technical University of Munich
Charite University, Berlin, Germany; Evangelisches Krankenhaus Bielefeld gGmbH

Completed

nTMS for Motor Mapping of Rolandic Lesions (Motorstim)

Glioma | Brain Metastases

Switzerland, Germany, Italy
University Hospital Tuebingen
Robert Bosch Gesellschaft für Medizinische Forschung mbH

Completed

Ice Plant Intensive Cream for the Prevention of Hand-Foot Syndrome in Breast Cancer: Pilot Randomized Controlled Trial (WIn-HFS)

Breast Cancer | Hand-Foot Syndrome

Germany
Gesellschaft fur Medizinische Innovation - Hamatologie...
Celgene; Amgen

Terminated

Therapy of Non-Hodgkin-Lymphoma by Combination of Lenalidomide + Rituximab, Dexa, High-dose ARA-C and CisP (R²-DHAP)

Diffuse Large B-cell Lymphoma (DLBCL) | Burkitt Lymphoma (BL) | Follicular Lymphoma Grade III (FL III°) | Mantle Cell Lymphoma (MCL), Blastoid Variant | Aggressive Marginal Zone Lymphoma (MZL)

Germany
Austrian Breast & Colorectal Cancer Study Group
Merck Gesellschaft mbH, Austria

Terminated

A Randomized, Placebo-controlled, Double-blind Phase II Study Evaluating if Glucophage Can Avoid Liver Injury Due to Chemotherapy Associated Steatosis (G-LUCAS)

Colorectal Cancer | Steatohepatitis

Austria
Heidelberg University
Gesellschaft fur Medizinische Innovation - Hamatologie und Onkologie mbH

Completed

A Trial of Treatment With Lenalidomide-Melphalan-Dexamethasone in Patients With Primary (AL) Amyloidosis (LEOMEX)

Primary Amyloidosis

Germany

Clinical Trials Sponsored by Grunenthal GmbH

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