Clinical Trials Sponsored by Salisbury NHS Foundation Trust

Total 3493 results

Guy's and St Thomas' NHS Foundation Trust
Queen's University, Belfast; University of Bristol; University of Glasgow; University... and other collaborators

Recruiting

INTERVAL - Intense Exercise Trial for Men With Metastatic Castrate-Resistant Prostate Cancer (INTERVAL)

Prostate Cancer

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
University of Nottingham; Liverpool Heart and Chest Hospital NHS Foundation... and other collaborators

Not yet recruiting

Using AI Within Digital Wound Monitoring of Surgical Wounds to Prioritise Non-healing Wounds for Urgent Review (WISDOM)

Surgical Wound | Heart; Surgery, Heart, Functional Disturbance as Result | Wound Healing Delayed

United Kingdom
Royal Devon and Exeter NHS Foundation Trust
King's College London; Newcastle University; NHS Tayside; University of Dundee; University... and other collaborators

Completed

TriMaster: Study of a DPP4 Inhibitor, SGLT2 Inhibitor and Thiazolidinedione as Third Line Therapy in Patients With Type 2 Diabetes. (TriMaster)

Type 2 Diabetes

United Kingdom
Cancer Research UK
Royal Marsden NHS Foundation Trust; Hoffmann-La Roche; University of Manchester; University of Birmingham

Recruiting

DETERMINE Trial Treatment Arm 01: Alectinib in Adult, Teenage/Young Adults (TYA) and Paediatric Patients With ALK Positive Cancers (DETERMINE)

Neoplasms by Histologic Type | Lymphoma | Lymphoproliferative Disorders | Neoplasms by Site | Renal Cell Carcinoma | Cancer | Solid Tumor | Anaplastic Large Cell Lymphoma | Neuroblastoma | Malignant Neoplasm | Haematological Malignancy

United Kingdom
Cancer Research UK
Royal Marsden NHS Foundation Trust; Hoffmann-La Roche; University of Manchester; University of Birmingham

Recruiting

DETERMINE Trial Treatment Arm 02: Atezolizumab in Adult, Teenage/Young Adults and Paediatric Patients With Cancers With High Tumour Mutational Burden (TMB) or Microsatellite Instability-high (MSI-high) or Proven Constitutional Mismatch Repair Deficiency (CMMRD) Disposition (DETERMINE)

Melanoma | Neoplasms by Histologic Type | Lymphoproliferative Disorders | Neoplasms by Site | Cancer | Colorectal Neoplasms | Endometrial Neoplasms | Malignant Neoplasm | Malignancy

United Kingdom
University of Manchester
National Institute for Health Research, United Kingdom; Greater Manchester...

Completed

Youth Metacognitive Therapy Feasibility Trial (YoMETA)

Depression | Anxiety Disorders | Child Mental Disorder

United Kingdom
King's College London
National Institute for Health Research, United Kingdom; South London and Maudsley...

Completed

Electronic Clinical Decision Support for Diabetes and Dysglycaemia in Secondary Mental Healthcare

Diabetes Mellitus | Dysglycemia | Severe Mental Disorder | Staff Attitude

United Kingdom
Keele University
Guy's and St Thomas' NHS Foundation Trust; University of Southampton; University... and other collaborators

Active, not recruiting

Work And Vocational advicE Study - Effectiveness of Adding a Brief Vocational Support Intervention to Usual Primary Care (WAVE)

Musculoskeletal Pain | Mental Health Disorder | Mental Health Issue | Absence | Other Physical Health Condition

United Kingdom
University of Birmingham
East Kent Hospitals University NHS Foundation Trust; National Institute for...

Active, not recruiting

Accuracy of Glomerular Filtration Rate (GFR) Estimation Using Creatinine and Cystatin C and Albuminuria (eGFR-C)

Chronic Kidney Diseases

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
University of Cambridge; Medical Research Council Cognition and Brain Sciences...

Enrolling by invitation

Minimizing Facial Nerve Stimulation in Cochlear Implants

Hearing Loss | Hearing Loss, Sensorineural | Cochlear Hearing Loss | Facial Nerve Injury | Nerve Disorders

United Kingdom
Imperial College London
Cambridge University Hospitals NHS Foundation Trust; University of Manchester; Food Standards Agency, United Kingdom

Completed

Mechanisms Underlying Peanut Allergic Reactions in TRACE Peanut Study Participants: Extension Study (TRACEextension)

Food Hypersensitivity | Peanut Hypersensitivity
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; Weston Park Hospital Cancer Charity; Sheffield Hospitals...

Completed

Lung HeXeRT: Helium, Xenon MRI for NSCLC Patients (HeXeRT)

NSCLC

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
University of Oxford; Engineering and Physical Sciences Research Council, UK

Completed

Validation of Respiration Rate Algorithms

Respiratory Rate | Pulse Oximetry

United Kingdom
Imperial College London
University of Southern California; Guy's and St Thomas' NHS Foundation Trust; Ipse... and other collaborators

Terminated

A Study to Assess the Ability of a Novel Endocrine Treatment for Breast Cancer, Irosustat, to Slow Down Cancer Growth (IPET)

Breast Neoplasms

United Kingdom
Liverpool Heart and Chest Hospital NHS Foundation...
National Institute for Health Research, United Kingdom; Biolife LLC; The Johnson...

Terminated

Assessment of Radial Artery Complications Whilst Achieving Rapid Haemostasis (ARCH)

Injury; Blood Vessel, Wrist, Radial Artery

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
Pontificia Universidad Catolica de Chile; University of Rotterdam, The Netherlands

Not yet recruiting

UK ANDROMEDA-Shock-2 RCT

Septic Shock
Cancer Research UK
Royal Marsden NHS Foundation Trust; Hoffmann-La Roche; University of Manchester; University of Birmingham

Recruiting

DETERMINE Trial Treatment Arm 03: Entrectinib in Adult, Teenage/Young Adults and Paediatric Patients With ROS1 Gene Fusion-positive Cancers. (DETERMINE)

Glioma | Melanoma | Neoplasms by Histologic Type | Lymphoproliferative Disorders | Neoplasms by Site | Cancer | Brain Neoplasms | Solid Tumor | Malignant Neoplasm | Malignancy | Haematological Malignancy

United Kingdom
Cancer Research UK
Royal Marsden NHS Foundation Trust; Hoffmann-La Roche; University of Manchester; University of Birmingham

Recruiting

DETERMINE (Determining Extended Therapeutic Indications for Existing Drugs in Rare Molecularly Defined Indications Using a National Evaluation Platform Trial) - Master Screening Protocol (DETERMINE)

Solid Tumor | Haematological Malignancy

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
National Institute for Health Research, United Kingdom; Wolfson Brain Imaging...

Recruiting

Quantiative MRI and Myelin-PET for the Assessment of Degenerative Cervical Myelopathy (IMAGE-DCM)

Cervical Spondylosis With Myelopathy | Degenerative Cervical Myelopathy

United Kingdom
University of Sydney
Northern Care Alliance NHS Foundation Trust; Waitemata District Health Board; Australasian Kidney Trials Network

Recruiting

Better Evidence and Translation for Calciphylaxis (BEAT-Calci)

Calciphylaxis

Australia, New Zealand
Great Ormond Street Hospital for Children NHS Foundation...
Hospices Civils de Lyon; Heidelberg University; Istanbul University

Active, not recruiting

Comparison of Pre- vs Post-dilution Haemodiafiltration in Children

Haemodiafiltration

United Kingdom, France, Germany, Turkey
Cambridge University Hospitals NHS Foundation Trust
University of Pennsylvania; Roche Pharma AG; Genentech, Inc.; Arthritis Research...

Completed

Rituximab Vasculitis Maintenance Study (RITAZAREM)

Microscopic Polyangiitis | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis | Wegener Granulomatosis

United States, Canada, United Kingdom, Sweden, New Zealand, Ireland, Australia, Italy, Czechia, Japan
King's College London
National Institute for Health Research, United Kingdom; South London and Maudsley...

Completed

High Intensity Interval Training in Severe Mental Illness

Schizophrenia | Bipolar Disorder | Major Depressive Disorder

United Kingdom
Professor Christi Deaton
University of Oxford; University of Manchester; Keele University

Completed

Optimising Management of Patients With Heart Failure With Preserved Ejection Fraction in Primary Care (OPTIMISEHFpEF)

Heart Failure With Preserved Ejection Fraction

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...
Yale University; Flinders University; Swinburne University of Technology

Completed

Electroretinogram in Autistic Spectrum Disorders (ERG in ASD)

Autism Spectrum Disorder

United States, United Kingdom, Australia
Royal Brompton & Harefield NHS Foundation Trust
University College London Hospitals; Imperial College London; University of East...

Completed

Rituximab Versus Cyclophosphamide in Connective Tissue Disease-ILD (RECITAL)

Interstitial Lung Disease | Scleroderma | Idiopathic Inflammatory Myositis | Mixed Connective Tissue Disease

United Kingdom
Julie Dawson
Medical Research Council; University of East Anglia

Completed

Production of a Device to Obtain Continuous Ambulatory Vestibular Assessment (CAVA) - Healthy Volunteer Trial (CAVA)

Optokinetic Nystagmus

United Kingdom
King's College Hospital NHS Trust
Barts and the London School of Medicine and Dentistry; Fetal Medicine Foundation

Unknown

The BEET-BP Trial - Investigating the Effect of Dietary Nitrates on Hypertension in Pregnancy

Pre-Eclampsia | Hypertension in Pregnancy | Gestational Hypertension | Pregnancy Induced Hypertension

United Kingdom
Quadram Institute Bioscience
Norfolk and Norwich University Hospitals NHS Foundation Trust; University of... and other collaborators

Unknown

Microbial Dysbiosis in Rheumatoid Arthritis (MyRA)

Rheumatoid Arthritis

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College London; National Institute for Health Research, United Kingdom

Completed

Role of Anti-IgE in Severe Childhood Eczema (ADAPT)

Child | Atopic Dermatitis | Atopic Eczema

United Kingdom
Royal Devon and Exeter NHS Foundation Trust
Merck Sharp & Dohme LLC; Pfizer; AbbVie; CORE; Napp Pharmaceuticals Limited

Unknown

Personalising Anti-TNF Therapy in Crohns Disease (PANTS) (PANTS)

Crohn Disease

United Kingdom
Royal Devon and Exeter NHS Foundation Trust
National Institute for Health Research, United Kingdom; University of Exeter

Completed

Predicting Response to Incretin Based Agents in Type 2 Diabetes (PRIBA)

Type2 Diabetes

United Kingdom
University of Edinburgh
Royal Brompton & Harefield NHS Foundation Trust; Royal Infirmary of Edinburgh; Golden Jubilee National Hospital

Completed

DEtection of Cellular Inflammation With FERumoxytol in the HEART (DECIFER)

Myocarditis | Healthy Volunteers | Cardiac Transplant | Cardiac Sarcoid

United Kingdom
University Hospital Schleswig-Holstein
Johannes Gutenberg University Mainz; Great Ormond Street Hospital for Children...

Completed

Endomicroscopy, IBS and Food Intolerance

Food Intolerance | Inflammatory Bowel Syndrome | Endomicroscopy

Germany
University of Southampton
Wyeth is now a wholly owned subsidiary of Pfizer; Hampshire Hospitals NHS Foundation...

Completed

Safety and Tolerability of Etanercept in Alzheimer's Disease (STEADI-09)

Alzheimer's Disease

United Kingdom
Queen Mary University of London
Barts & The London NHS Trust; Pharma Nord; Fischer Family Trust; The AIM Foundation and other collaborators

Completed

Trial of Vitamin D to Reduce Risk and Severity of COVID-19 and Other Acute Respiratory Infections (CORONAVIT)

Covid19 | Acute Respiratory Tract Infection

United Kingdom
Cancer Research UK
Royal Marsden NHS Foundation Trust; Hoffmann-La Roche; University of Manchester; University of Birmingham

Recruiting

DETERMINE Trial Treatment Arm 04: Trastuzumab in Combination With Pertuzumab in Adult, Teenage/Young Adult and Paediatric Patients With Cancers With HER2 Amplification or Activating Mutations (DETERMINE)

Colorectal Neoplasms | Ovarian Neoplasms | Solid Tumor | Gallbladder Neoplasms | Prostatic Neoplasm | Pancreatic Neoplasm | Lung Neoplasm | Haematological Malignancy | Urinary Bladder Neoplasm | Skin Neoplasm | Salivary Gland Neoplasm

United Kingdom
Cancer Research UK
Royal Marsden NHS Foundation Trust; Hoffmann-La Roche; University of Manchester; University of Birmingham

Recruiting

DETERMINE Trial Treatment Arm 05: Vemurafenib in Combination With Cobimetinib in Adult Patients With BRAF Positive Cancers. (DETERMINE)

Glioma | Melanoma | Carcinoma, Non-Small-Cell Lung | Multiple Myeloma | Colorectal Neoplasms | Ovarian Neoplasms | Solid Tumor | Thyroid Cancer, Papillary | Thyroid Carcinoma, Anaplastic | Laryngeal Neoplasms | Erdheim-Chester Disease | Haematological Malignancy

United Kingdom
Cardiff and Vale University Health Board
Norfolk and Norwich University Hospitals NHS Foundation Trust; Cardiff Metropolitan...

Enrolling by invitation

Pacing in Heart Failure With Preserved LVEF (MAPPLE)

Heart Failure

United Kingdom
King's College London
National Institute for Health Research, United Kingdom; South London and Maudsley...

Completed

Group Training for Social Skills in Psychosis (GRASP)

Psychotic Disorders

United Kingdom
Norfolk and Norwich University Hospitals NHS Foundation...
University of East Anglia; Ministry of Defence, United Kingdom

Completed

Pharmacokinetic and PHarmacodynamic Analysis and Evaluation of Teriparatide (PTH 1-34) Between Sexes (PHAB)

Stress Fracture

United Kingdom
Julie Dawson
Medical Research Council; University of East Anglia

Completed

CAVA: Electrode Pad Appraisal Trial (CEPAT)

Tolerability of Wear of Electrode Pads

United Kingdom
Gene Signal SAS
Moorfields Eye Hospital NHS Foundation Trust; Johannes Gutenberg University... and other collaborators

Unknown

Trial of Aganirsen in iCRVO Patients at Risk of Developing NVG (STRONG)

Neovascular Glaucoma | Ischaemic Central Retinal Vein Occlusion
Prof Janet Brown
Sheffield Teaching Hospitals NHS Foundation Trust; Weston Park Hospital Cancer...

Unknown

Assessment of Bone Loss in Men Receiving Treatment for Prostate Cancer (ANTELOPE)

Prostate Cancer

United Kingdom
University of Birmingham
University Hospital Birmingham NHS Foundation Trust; Dowager Countess Eleanor... and other collaborators

Unknown

Understanding Acute Sarcopenia

Sarcopenia

United Kingdom
University College, London
London School of Hygiene and Tropical Medicine; King's College London; University... and other collaborators

Recruiting

Deep Brain Stimulation in Tourette Syndrome (Op-TICS)

Tourette Syndrome | Deep Brain Stimulation

United Kingdom
UMC Utrecht
Karolinska University Hospital; Erasmus Medical Center; Great Ormond Street Hospital... and other collaborators

Not yet recruiting

Primary Posterior Tracheopexy Prevents Tracheal Collapse (PORTRAIT)

Oesophageal Atresia | Tracheomalacia | Oesophageal Atresia With Tracheo-Oesophageal Fistula
Royal United Hospitals Bath NHS Foundation Trust
University of Oxford; Biotronik SE & Co. KG; University of Bath; RUHX (Official...

Recruiting

Super-Rehab: a Novel Approach to Reverse Atrial Fibrillation (SuRe-AF)

Atrial Fibrillation | Overweight and Obesity

United Kingdom
University of Cambridge
Cambridgeshire and Peterborough NHS Foundation Trust; The Gianna Angelopoulos... and other collaborators

Not yet recruiting

Optical Neuroimaging and Cognition (ONAC)

Alzheimer Disease | Mild Cognitive Impairment | Dementia With Lewy Bodies
Al-Quds University
Assiut University; Tanta University; Papworth Hospital NHS Foundation Trust; European... and other collaborators

Recruiting

Post-Operative Kinesio Taping Impact on Pain in Thoracotomy vs Thoracoscopy

Post Operative Pain

Italy, Egypt, United Kingdom, Palestinian Territory, occupied

Clinical Trials Sponsored by Salisbury NHS Foundation Trust

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