Search clinical trials for: Multiple ascending dose (MAD)

Total 32966 results

Merck Sharp & Dohme LLC

Terminated

A Study to Evaluate Rofecoxib Versus Placebo and Diclofenac in Patients With Acute Painful Rotator Cuff Syndrome

Pain

France
University of Turku
Hoffmann-La Roche

Unknown

Safety and Efficacy Study of Intravenous Loading Dose of Ibandronate in Breast Cancer Patients

Breast Cancer

Finland
Hopital Lariboisière
Ministry of Health, France

Completed

Impact of Continuous Venovenous Haemofiltration on Organ Failure During the Early Phase of Severe Sepsis

Sepsis | Gram-Negative Bacterial Infections | Gram-Positive Bacterial Infections | Shock, Septic | Bacteremia | Pneumonia, Bacterial

France
University of Turin, Italy

Completed

Melphalan, Prednisone, Thalidomide And Bortezomib In Advanced And Refractory Multiple Myeloma Patients

Multiple Myeloma

Italy
University of Turin, Italy

Completed

Melphalan, Prednisone, and CC-5013 (Revlimid) as Induction Therapy in Multiple Myeloma

Multiple Myeloma

Italy
Steno Diabetes Center Copenhagen

Completed

Maximal Dose of Angiotensin Converting Enzyme (ACE) Inhibitor for Treatment of Diabetic Kidney Disease

Diabetic Nephropathy | Diabetes Mellitus, Type I

Denmark
Denver Health and Hospital Authority
McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Completed

Effects of Therapeutic Doses of Acetaminophen in Moderate Drinkers

Moderate Alcohol Consumption (1-3 Drinks Per Day)
Novalar Pharmaceuticals, Inc.

Completed

Study of NV-101 for Efficacy, Pharmacodynamics, and Safety in Dental Patients Undergoing Maxillary Procedures

Anesthesia, Dental

United States
Peter MacCallum Cancer Centre, Australia
The Leukemia and Lymphoma Society

Completed

ATRA Plus G-CSF for Mobilization of Hematopoietic Stem and Progenitor Cells

Multiple Myeloma | Cutaneous Lymphoma

Australia
Assistance Publique - Hôpitaux de Paris
Danone Institute International

Terminated

Effects of Peptides Derived From Fermented Milk on Blood Pressure Regulation System in Healthy Volunteers.

Healthy

France
Pfizer

Completed

Safety and Efficacy of (PN-152,243)/PN-196,444 in the Prevention of Thrombocytopenia

Neoplasms | Multiple Myeloma | Lymphoma, Malignant | Thrombocytopenia

United States, Argentina, Mexico
AGO Study Group

Completed

Randomized, Multicenter, 2-Dose Level. Open-Label, Phase IIa Study With the Intraperitoneally Infused Trifunctional Bispecific Antibody Removab(TM) (Anti-EpCAM x Anti-CD3) to Select the Better Dose Level in Platinum Refractory Epithelial Ovarian Cancer Patients

Fallopian Tube Neoplasms | Peritoneal Neoplasms | Ovarian Cancer

Germany
Xcyte Therapies

Unknown

T Cell Immunotherapy for Multiple Myeloma Patients Undergoing a Bone Marrow Transplant

Multiple Myeloma

United States
Kos Pharmaceuticals

Completed

The Dose Response of Niacin ER/Lovastatin on Peak Walking Time (PWT) in Patients With Intermittent Claudication - TROPIC

Intermittent Claudication | Peripheral Vascular Disease

United States
Novacea

Unknown

Study of High-Dose Pulse Administration DN-101 (Calcitriol) in Patients With Myelodysplastic Syndrome (MDS)

Myelodysplastic Syndrome

United States
Kos Pharmaceuticals

Completed

Safety & Efficacy of a Combination Niacin ER/Simvastatin in Patients With Dyslipidemia: A Dose-Ranging Study - SEACOAST

Hypercholesterolemia
Assistance Publique - Hôpitaux de Paris

Terminated

Analgesic Effect in Children of Low-Dose Ketamine for Mucositis Treated by Patient-Controlled Analgesia With Morphine

Cancer | Mucositis

France
Hospital Clinic of Barcelona

Completed

Study Comparing Reducing the Dose of Stavudine Versus Switching to Tenofovir in HIV-Infected Patients Receiving Antiretroviral Therapy

HIV Infections | Lipoatrophy
Chang Gung Memorial Hospital

Completed

Long-Term Lead Chelation Therapy and Progressive Renal Insufficiency

Urologic Disease

China
National Cheng-Kung University Hospital

Unknown

Multiple Grain in Type 2 Diabetes

Diabetes Mellitus

Taiwan
Angiogenix

Unknown

Efficacy Study of Oral L-Citrulline in Patients Taking Simvastatin With Peripheral Arterial Disease

Peripheral Arterial Disease | Intermittent Claudication

Russian Federation
Washington University School of Medicine

Terminated

Single Dose Thymoglobulin for Induction in Adult Renal Allograft Recipients

Kidney Transplantation

United States
Eunice Kennedy Shriver National Institute of Child...

Unknown

Effects of Spinal Cord Injury on Female Sexual Response

Multiple Sclerosis | Female Sexual Dysfunction | Spinal Cord Injury

United States
UMC Utrecht
Children's Hospital of Philadelphia; Netherlands Brain Foundation

Unknown

Genetics and Psychopathology in the 22q11 Deletion Syndrome

Chromosome 22q11.2 Deletion Syndrome

United States, Netherlands
Royal Marsden NHS Foundation Trust

Completed

A Randomized Trial of Human Growth Hormone (hGH) vs Placebo in Intensively Treated Haemato-Oncology Patients.

Acute Myeloid Leukemia | Multiple Myeloma | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome
University Health Network, Toronto

Unknown

Proper Dosage of Ketamine in Intravenous Regional Anesthesia

Pain.

Canada
Odense University Hospital

Unknown

Insulin NovoRapid Versus Actrapid in Treatment of Type 1 Diabetic Patients During Daily Adjustment of Insulin Dose

Type 1 Diabetes Mellitus

Denmark
Bayside Health

Unknown

Atorvastatin in Myeloma

Myeloma

Australia
GlaxoSmithKline

Completed

Comparison of Adjuvanted Hepatitis B Vaccine to Double Dose of Engerix™-B in Pre- /Haemodialysis Patients Aged ≥15 Years

Hepatitis B

Czech Republic, Malaysia, Spain
MedImmune LLC
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Trial to Compare the Safety, Tolerability, Immunogenicity and Efficacy of Three Dose Levels of a Liquid Formulation of Influenza Virus Vaccine, (CAIV-T) in Healthy Children

Healthy

Philippines, Thailand
Johann Wolfgang Goethe University Hospital

Completed

Fish Oil and Asthma in House Dust Mite Allergy

Allergic Asthma | House Dust Mite Allergy | Bronchial Inflammation
elbion AG

Terminated

ELB139 Given Orally to Patients With Concurrent Panic Disorder, Challenged by CO2 Inhalation After a Single Dose and One Week of Treatment

Panic Disorder

Germany, Netherlands
Mednax Center for Research, Education, Quality...

Completed

Dose Comparison of Amino Acids on Growth in Premature Neonates

Malnutrition

United States
The Alvin and Lois Lapidus Cancer Institute
Ortho Biotech Products, L.P.

Unknown

A Dose Study of Doxil in a Dose Dense, 14 Day CDOP/Rituximab Regimen for Patients With Diffuse Large B-Cell Non-Hodgkin Lymphoma (NHL)> 60 Years or With Compromised Cardiac Status.

Lymphoma, Non-Hodgkin | Diffuse Large B Cell Lymphoma

United States
Korean Multiple Myeloma Working Party
Janssen-Cilag Ltd.

Unknown

Sequential VAD and VTD Followed by HDT With ASCT and Velcade Maintenance for NDMM

Multiple Myeloma

Korea, Republic of
Herlev Hospital

Completed

Dose of Norepinephrine and the Concentration of L-Lactate in the Rectum and Stomach in Patients With Septic Shock.

Septic Shock

Denmark
Institute of Child Health

Completed

Vitamins and Minerals for Children With Downs Syndrome

Trisiomy 21 (Down Syndrome)

United Kingdom
Lampiris, Harry W., M.D.
Abbott

Unknown

High Dose Ritonavir/Lopinavir Liquid Formulation in Salvage Therapy for Protease Inhibitor Resistant HIV Disease

HIV | AIDS

United States
University of Bologna

Completed

Autologous Transplantation for Multiple Myeloma

Multiple Myeloma
Weill Medical College of Cornell University
Forest Laboratories

Terminated

The Efficacy and Safety of Escitalopram for Depression in Multiple Sclerosis

Depression | Multiple Sclerosis

United States
International Union Against Tuberculosis and Lung...
United States Agency for International Development (USAID)

Unknown

Multicenter Trial for the Evaluation of a Fixed Dose Combined Tablet for the Treatment of Pulmonary Tuberculosis

Tuberculosis

Algeria, Bolivia, Colombia, Guinea, Mozambique, Nepal, Peru, Tanzania, Vietnam
Bethesda General Hospital, Hoogeveen
Novo Nordisk A/S; Merck Sharp & Dohme LLC; Merck KGaA, Darmstadt, Germany; Takeda; LifeSc... and other collaborators

Completed

The HOME Trial: Hyperinsulinaemia: the Outcome of Its Metabolic Effects, a Randomized Controlled Trial

Type 2 Diabetes Mellitus

Netherlands
Technische Universität Dresden

Completed

High Dose Candesartan Versus Quinapril for Restenosis Prophylaxis After Stent Angioplasty

Arterial Occlusive Diseases

Germany
Gustave Roussy, Cancer Campus, Grand Paris

Suspended

Study of Peri-Operative Docetaxel Plus Laparoscopic Radical Prostatectomy in Prostate Cancer Patients

Prostate Cancer

France
University of Rochester

Completed

Feasibility of Treatment of Cancer Involving the Liver With High Dose Radiation

Neoplasm Metastasis | Liver Neoplasms

United States
QuatRx Pharmaceuticals Company

Completed

Safety and Efficacy Study of Two Dose Regimens of Becocalcidiol in the Treatment of Plaque-Type Psoriasis

Psoriasis

United States
Institute for Clinical Research

Unknown

Combination Therapy (Provigil + Avonex) to Treat Cognitive Problems in MS

Relapsing-Remitting Multiple Sclerosis

United States
Sheba Medical Center

Unknown

TCV -01-002: T-Cell Vaccination in the Treatment of Probable Multiple Sclerosis

Multiple Sclerosis

Israel
National Taiwan University Hospital

Unknown

A Trial to Evaluate the Loading Dose Required to Achieve Therapeutic Serum Teicoplanin Concentration Timely

Staphylococcal Infections

Taiwan
Sanofi

Completed

Dose-Exposure-Response in Type 1 Diabetes Mellitus

Diabetes Mellitus, Type I

Germany

Search clinical trials for: Multiple ascending dose (MAD)

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Cambodia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations