Search clinical trials for: Class II

Total 34002 results

National Center for Research Resources (NCRR)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); University...

Completed

Phase II Randomized Study of the Effects of Growth Hormone on Children and Adolescents on Maintenance Dialysis

End Stage Renal Disease | Renal Osteodystrophy

United States
National Institute on Drug Abuse (NIDA)
University of Texas

Completed

Phase II Double-Blind, Placebo-Controlled Study of the Reinforcing Effects of Alprazolam in Patients With Anxiety

Panic Disorder | Anxiety Disorder

United States
National Center for Research Resources (NCRR)
University of Tennessee

Completed

Phase III Randomized, Double-Blind, Placebo-Controlled Study of Mexiletine for Painful Diabetic Neuropathy

Pain | Diabetic Neuropathies | Paresthesia
The Avicena Group

Unknown

Study of Creatine Monohydrate in Patients With Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis (ALS)

United States
University of Minnesota

Completed

Phase I/II Study of Total Body Irradiation, Cyclophosphamide, and Fludarabine Followed by Alternate Donor Hematopoietic Cell Transplantation in Patients With Fanconi's Anemia

Fanconi's Anemia

United States
National Center for Research Resources (NCRR)
University of Alabama at Birmingham

Completed

Phase III Randomized Study of Oral Acyclovir in Infants With Herpes Simplex Virus Infection Limited to Skin, Eyes, and Mouth

Herpes Simplex

United States, Canada
National Center for Research Resources (NCRR)
National Institute of Neurological Disorders and Stroke (NINDS); University...

Completed

Phase III Randomized, Double-Blind Study of Prednisone for Duchenne Muscular Dystrophy

Duchenne Muscular Dystrophy
National Center for Research Resources (NCRR)
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Phase I/II Study of High-Dose Acyclovir for Central Nervous System or Disseminated Neonatal Herpes Simplex Virus Infection

Herpes Simplex
National Center for Research Resources (NCRR)
Johns Hopkins University

Completed

Phase II Study of Sodium Phenylbutyrate, Sodium Benzoate, Sodium Phenylacetate, and Dietary Intervention for Urea Cycle Disorders

Amino Acid Metabolism, Inborn Errors
R W Johnson Pharmaceutical Research Institute

Completed

A Double-Blind Study to Evaluate the Safety and Pharmacokinetics of L-Ofloxacin (RWJ 25213) in Subjects With HIV Infection

HIV Infections

United States
Glaxo Wellcome

Completed

A Phase III, Randomized, Double-Blind, Multicentre Study to Evaluate the Safety and Efficacy of 1592U89 in Patients With AIDS Dementia Complex

HIV Infections | AIDS Dementia Complex

United States, Canada
National Center for Research Resources (NCRR)
Yale University

Completed

Phase II Double Blind Placebo Controlled Trial of Risperidone in Tourette Syndrome

Tourette Syndrome
National Center for Research Resources (NCRR)

Unknown

Classical Conditioning to Treat Allergic Airway Diseases

Allergic Airway Disease

United States
National Institute of Neurological Disorders and...
Harborview Injury Prevention and Research Center

Completed

Phase III Double Blind Trial of Valproate Sodium for Prophylaxis of Post Traumatic Seizures

Post-Traumatic Seizure Disorder | Head Injuries
Hoffmann-La Roche

Completed

A Study of ddC in Patients With AIDS or Advanced AIDS-Related Complex (ARC) Who Have Not Had Success With Zidovudine (AZT)

HIV Infections

United States
Sandoz

Completed

A Phase I/II Pilot Study of Simultaneously Administered Rhu GM-CSF ( CHO Cell ) and Azidothymidine ( AZT ) in Patients With Severe HIV Infection and Leukopenia: Pharmacokinetics and Feasibility

HIV Infections | Cytopenias

United States
Tularik

Terminated

T138067 Versus Doxorubicin in Chemotherapy-Naive, Unresectable, Hepatocellular Carcinoma Patients

Hepatocellular Carcinoma

United States, Russian Federation, United Kingdom, Singapore, Thailand, Ukraine, Brazil, China, Poland, Puerto Rico, South Africa
Sandoz

Completed

A Phase I/II Trial to Assess the Safety and Tolerance of Escalating Doses of a Human Anti-Cytomegalovirus Monoclonal Antibody (SDZ MSL-109) in Patients With the Acquired Immunodeficiency Syndrome and CMV Retinitis

HIV Infections | Cytomegalovirus Retinitis

United States
National Center for Research Resources (NCRR)
Ohio State University

Completed

Phase II Study of Leuprolide and Testosterone for Men With Kennedy's Disease or Other Motor Neuron Disease

Amyotrophic Lateral Sclerosis | Spinal Muscular Atrophy | Spinobulbar Muscular Atrophy
National Center for Research Resources (NCRR)
University of Texas

Unknown

Phase I/II Study of Neuroendocrine Dysfunction in Patients With Closed Head Injuries

Brain Injury

United States
National Center for Research Resources (NCRR)
Tulane University School of Medicine

Completed

Phase III Randomized Study of High Vs Standard Dose of Interferon Alfa for Chronic Hepatitis C

Hepatitis C
National Center for Research Resources (NCRR)
Oregon Health and Science University

Unknown

Phase II Study of Dietary Cholesterol for Smith-Lemli-Opitz Syndrome

Smith-Lemli-Opitz Syndrome

United States
National Center for Research Resources (NCRR)
Baylor College of Medicine

Completed

Phase II Study of the Effect of Leuprolide Acetate and Spironolactone on Insulin Resistance in Hyperandrogenic Women With Polycystic Ovarian Disease or Hyperandrogenism Insulin Resistance Acanthosis Nigricans Syndrome

Polycystic Ovary Syndrome | Acanthosis Nigricans
Eunice Kennedy Shriver National Institute of Child...
Rockefeller University

Completed

Phase II Randomized Study of Tin Mesoporphyrin for Neonatal Hyperbilirubinemia

Hyperbilirubinemia | Glucosephosphate Dehydrogenase Deficiency | Hemolytic Disease of Newborn

United States
National Center for Research Resources (NCRR)
University of North Carolina

Completed

Phase I/II Study of Monoclonal Factor IX Concentrate for Factor IX Deficiency

Hemophilia B | Factor IX Deficiency
National Institute of Allergy and Infectious Diseases...
Genentech, Inc.

Completed

A Phase I Multicenter Study of the Safety and Immunogenicity of MN rgp120/HIV-1 Vaccine Given Either Alone or in Combination With IIIB rgp120/HIV-1 Vaccine in Healthy Adult Subjects (NOTE: Original Study Extended ONLY for Patients Previously Enrolled on VEU 009)

HIV Infections

United States
Glaxo Wellcome

Completed

The Efficacy and Safety of Retrovir in Patients Infected With HIV Who Are Asymptomatic (CDC Group II) or Have Persistent Generalized Lymphadenopathy (CDC Group III)

HIV Infections | Lymphatic Disease

United States
Baker Norton Pharmaceuticals

Completed

Paclitaxel in Advanced Refractory Kaposi's Sarcoma (AIDS-KS): A Phase II Trial of Paclitaxel From Baker Norton Pharmaceuticals

HIV Infections | Sarcoma, Kaposi

United States
National Center for Research Resources (NCRR)
University of Pittsburgh

Completed

Phase III Randomized, Double-Blind, Placebo-Controlled Study of Oral Iloprost for Raynaud's Phenomenon Secondary to Systemic Sclerosis

Systemic Sclerosis | Raynaud Disease
Fairview University Medical Center

Unknown

Pilot Study of Unrelated Donor Hematopoietic Stem Cell Transplantation in Patients With Life Threatening Hemophagocytic Disorders

Hemophagocytic Lymphohistiocytosis | Graft Versus Host Disease | Chediak-Higashi Syndrome | Virus-Associated Hemophagocytic Syndrome | X-Linked Lymphoproliferative Syndrome | Familial Erythrophagocytic Lymphohistiocytosis

United States
National Center for Research Resources (NCRR)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); University...

Completed

Phase III Randomized Study of Ursodiol With Vs Without Methotrexate for Primary Biliary Cirrhosis

Liver Cirrhosis, Biliary
Aronex Pharmaceuticals

Unknown

A Safety and Effectiveness Study of Aroplatin in Patients With Advanced Solid Malignancies

Neoplasms | Colorectal Neoplasms | Hepatocellular Carcinoma | Pancreatic Neoplasms | Esophageal Neoplasms | Ovarian Neoplasms

United States
National Institute of Neurological Disorders and...
University of California, San Francisco

Completed

Phase III Randomized Study of Diazepam Vs Lorazepam Vs Placebo for Prehospital Treatment of Status Epilepticus

Status Epilepticus
Genelabs Technologies

Completed

A Randomized Phase II Efficacy, Activity and Safety Study of GLQ223 Alone and in Combination With Zidovudine in Symptomatic HIV-Infected Patients Without Prior Treatment With GLQ223 or Trichosanthin

HIV Infections

United States
Schering-Plough

Completed

Phase III Ganciclovir +/- rGM-CSF for AIDS-Related CMV Retinitis

HIV Infections | Cytomegalovirus Retinitis

United States
Amgen

Completed

An Open-Label Phase I/II Study of Recombinant Granulocyte Colony Stimulating Factor (r-metHuG-CSF) and Recombinant Erythropoietin (rHuEPO) Given Subcutaneously Along With Zidovudine (AZT) to Patients With the Acquired Immune Deficiency Syndrome (AIDS) or Severe AIDS-Related Complex (ARC)

HIV Infections

United States
Lederle Laboratories

Completed

Phase II Study of Intravenous Novantrone(R) in the Treatment of AIDS Related Kaposi's Sarcoma

HIV Infections | Sarcoma, Kaposi

United States
National Center for Research Resources (NCRR)
University of California, Los Angeles

Completed

Phase III Randomized, Double-Blind, Placebo-Controlled Study of Oral Topiramate for Lennox-Gastaut Syndrome

Lennox-Gastaut Syndrome
Gilead Sciences

Completed

A Phase I/II Study of the Safety and Efficacy of Topical 1-(S)-(3-Hydroxy-2-Phosphonylmethoxypropyl)Cytosine Dihydrate (Cidofovir; HPMPC) in the Treatment of Refractory Mucocutaneous Herpes Simplex Disease in Patients With AIDS

HIV Infections | Herpes Simplex

United States, Canada
National Center for Research Resources (NCRR)
Roberts Pharmaceutical

Completed

Phase II Study of Midodrine for Neurogenic Orthostatic Hypotension

Orthostatic Hypotension

United States
National Center for Research Resources (NCRR)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other collaborators

Completed

Phase II Study of Recombinant Relaxin for Progressive Systemic Sclerosis

Systemic Sclerosis
National Center for Research Resources (NCRR)
Northwestern University

Completed

Phase II Randomized Study of Cidofovir for Peripheral Cytomegalovirus Retinitis

Acquired Immunodeficiency Syndrome | Cytomegalovirus Retinitis
Hoffmann-La Roche
Trimeris

Completed

T-20 With Anti-HIV Combination Therapy for Patients With Prior Anti-HIV Drug Treatment and/or Drug Resistance to Each of the Three Classes of Approved Anti-HIV Drugs

HIV Infections

United States, Canada
Corixa Corporation

Completed

Safety and Efficacy Study of Iodine-131 Anti-B1 Antibody Plus CHOP For Untreated Mantle Cell Lymphoma

Mantle Cell Lymphoma

United States
National Institute of Neurological Disorders and...
University of Pittsburgh

Unknown

Phase II Randomized Study of Stereotactic Radiosurgery Plus Fractionated Whole-Brain Radiotherapy Vs Fractionated Whole-Brain Radiotherapy Alone for Multiple Primary or Metastatic Brain Tumors

Brain Neoplasms
Hoffmann-La Roche

Completed

A Phase IIIB Open-Label, Comparative Study to Evaluate Saquinavir Soft Gel Capsule (SGC) Treatment in Combination With Other Antiretrovirals in HIV-1 Infected Antiretroviral-Naive Patients

HIV Infections

United States
National Center for Research Resources (NCRR)
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Phase III Randomized, Double-Blind, Placebo-Controlled Study of Antenatal Thyrotropin-Releasing Hormone in Pregnant Women With Threatened Premature Delivery

Respiratory Distress Syndrome
National Center for Research Resources (NCRR)

Unknown

Chronic Thalidomide Administration in Patients Undergoing Chemoembolization for Unresectable Hepatocellular Cancer

Liver Cancer

United States
National Institute of Dental and Craniofacial Research...
Washington University School of Medicine

Completed

Phase III Randomized Study of the Effect of Postmenopausal Estrogen Replacement Therapy on Alveolar Bone Loss

Osteoporosis
National Center for Research Resources (NCRR)
National Institute of Allergy and Infectious Diseases (NIAID); Rockefeller...

Completed

Phase II Placebo Controlled Study of Thalidomide in Patients With Mycobacterial and HIV Infections

HIV Infections | Mycobacterium Infections | Tuberculosis

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