Search clinical trials for: DE-112

Total 2632 results

UniQure Biopharma B.V.

Not yet recruiting

Safety, Tolerability, and Efficacy Study of Intrathecally Administered Gene Therapy AMT-162 in Amyotrophic Lateral Sclerosis (ALS) Patients With SOD1 Mutations

Amyotrophic Lateral Sclerosis
IDP Discovery Pharma S.L.

Recruiting

A Phase 1/2 Study of IDP-121 in Patients With Relapsed/Refractory Hematologic Malignancies (CASSANDRA)

Chronic Lymphocytic Leukemia (CLL) | Diffuse Large B-Cell Lymphoma, Not Otherwise Specified | Multiple Myeloma (MM) | High Grade B-Cell Lymphoma, Not Otherwise Specified | Double Hit Lymphoma | Triple Hit Lymphoma

Spain
Chordia Therapeutics, Inc.
Theradex

Recruiting

A Study of CTX-712 in Relapsed/Refractory Acute Myeloid Leukemia and Higher Risk Myelodysplastic Syndromes

Acute Myeloid Leukemia | Myelodysplastic Syndromes

United States
Walter Reed Army Institute of Research (WRAIR)
National Institute of Mental Health (NIMH); National Intrepid Center of Excellence

Recruiting

CNS Correlates of Extended Sleep Restriction

Sleep Restriction

United States
Cue Biopharma

Recruiting

A Phase 1 in Patients With HLA-A*0201+ and WT1+ Recurrent/Metastatic Cancers

Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer

United States
Tarapeutics Science Inc.

Recruiting

A Study of HYML-122 in Patients With FLT3 Positive Relapsed or Refractory Acute Myeloid Leukemia (AML)

Relapsed or Refractory Acute Myeloid Leukemia (AML)

China
Aegle Therapeutics
Congressionally Directed Medical Research Programs

Recruiting

Safety of Extracellular Vesicles for Burn Wounds

Burns

United States
University of Alabama at Birmingham

Not yet recruiting

Understanding the Metabolic and Functional Derangement of Primary Mitral Regurgitation: a Feasibility Study Using Carbon 11(C-11) Acetate Cardiac Positron Emission Tomography Magnetic Resonance Imaging (PET-MRI)

Mitral Valve Regurgitation

United States
Aegle Therapeutics

Not yet recruiting

MSC EVs in Dystrophic Epidermolysis Bullosa

Dystrophic Epidermolysis Bullosa
4D Molecular Therapeutics

Active, not recruiting

Dose Escalation Study of Intravitreal 4D-110 in Patients With Choroideremia

Choroideremia

United States
ORIC Pharmaceuticals

Completed

Effect of Food on the Pharmacokinetics of ORIC-114

Food Effect in Healthy Participants

Australia
University of Pennsylvania

Terminated

11C-Acetate PET/CT Imaging As a Biomarker of Amyloid-Induced Neuroinflammation

Mild Cognitive Impairment

United States
Raziel Therapeutics Ltd.

Completed

An Open Label Study That Will Test Safety and Efficacy of RZL-012 Injection Into the Submental Fat in Chinese vs. Non-Chinese Subjects.

Submental Fat

United States
REGENXBIO Inc.

Active, not recruiting

RGX-111 Gene Therapy in Patients With MPS I

Hurler Syndrome | Hurler-Scheie Syndrome | Mucopolysaccharidosis Type I (MPS I)

United States, Brazil, Israel
Raziel Therapeutics Ltd.

Completed

An Open-label Study That Will Test a Second Treatment Session of RZL-012.

Submental Fat

United States
Dongkook Pharmaceutical Co., Ltd.

Active, not recruiting

Efficacy and Safety of DKB-119 in Patients in Crow's Feet

Crow's Feet

Korea, Republic of
University of Pennsylvania
University of Miami; Biogen; University of Kansas

Terminated

Multimodal Imaging Outcome Measures for ALS (Image ALS)

ALS

United States
Yonsei University

Completed

K-BASKET, TAS-117, PI3K/AKT Gene Aberration

Solid Tumor, Adult

Korea, Republic of
M.D. Anderson Cancer Center
Array BioPharma

Terminated

MEK Inhibitor 162 Relapsed and/or Refractory Acute Myeloid Leukemia (AML) and Poor Prognosis, Not Suitable for or Unwilling to Receive Standard Therapy

Leukemia

United States
argenx

Completed

A Study to Compare the PK, PD and Safety and Tolerability of a SC With an IV Formulation of ARGX-113 in Healthy Male Subjects

Bioavailability Study

Netherlands
Fusion Pharma LLC
Data Matrix Solutions; OCT Rus, LLC; Skolkovo Innovation Center

Unknown

Study to Evaluate Tolerability, Safety, Pharmacokinetics and Preliminary Efficacy of PF-114 for Oral Administration in Adults With Ph+ Chronic Myeloid Leukemia, Which is Resistant to the 2-nd Generation Bcr-Abl Inhibitors or Has T315I Mutation in the BCR-ABL Gene

Leukemia, Myelogenous, Chronic, BCR-ABL Positive | Chronic Myeloid Leukemia

Russian Federation
Jazz Pharmaceuticals

Completed

"Six-week Study of the Safety and Efficacy of JZP-110 in the Treatment of Excessive Sleepiness in OSA" (OSA)

Obstructive Sleep Apnea

United States, Finland, Germany, France, Sweden
Raziel Therapeutics Ltd.

Completed

Treatment of Women With Lipedema Involving Substantial Fat Above the Knee or of Women and Men With Nodular Dercum's Disease

Dercum Disease | Lipedema

United States
Johns Hopkins University
National Institute on Aging (NIA)

Completed

PET Imaging Study Using [11C]PIB in Subjects With AD & Healthy Volunteers

Alzheimer's Disease

United States
Synektik S.A.
European Commission

Completed

A Phase I Study of a Novel Tracer for Positron Emission Tomography "PET" Myocardial Perfusion Imaging "MPI"

Coronary Artery Disease
Vanda Pharmaceuticals

Completed

Safety and Efficacy of VEC-162 on Circadian Rhythm in Healthy Adult Volunteers

Circadian Rhythm Sleep Disorders

United States
BioMarin Pharmaceutical

Approved for marketing

BMN 110 US Expanded Access Program

Morquio A Syndrome | MPS IVA | Mucopolysaccharidosis IVA

United States, Puerto Rico
Baylor College of Medicine
Harris County Hospital District; The Methodist Hospital Research Institute

Withdrawn

GOAT; Phase I Open Label Study of CGTG-102, a GM-CSF Encoding Oncolytic Adenovirus, for Advanced Cancers (GOAT)

Solid Tumors | Tumors
Trillium Therapeutics Inc.

Completed

Safety Study of Single Intravesical Doses of TTI-1612 in Women With Interstitial Cystitis/Bladder Pain Syndrome

Interstitial Cystitis

Canada
Xigen SA

Completed

Safety, Tolerability and PK of a Single iv Infusion of 10, 40, and 80 µg/kg XG-102 Administered to Healthy Volunteers

Inflammation

Switzerland
Amgen

Terminated

A Study of AMG 114 Administered by Subcutaneous Injection for the Treatment of Anemia in Subjects With Non-Myeloid Malignancies Receiving Multicycle Chemotherapy

Cancer | Anemia
Taysha Gene Therapies, Inc.

Recruiting

Safety and Efficacy of TSHA-102 in Pediatric Females With Rett Syndrome (REVEAL Pediatric Study)

Rett Syndrome

United States, United Kingdom
Multitude Therapeutics Inc.

Recruiting

AMT-116 in Patients With Advanced Solid Tumors

Advanced Solid Tumor

Australia
Beijing InnoCare Pharma Tech Co., Ltd.

Recruiting

A Study of ICP-192 in Patients With FGFR2-Rearranged Unresectable or Metastatic Intrahepatic Cholangiocarcinoma

Intrahepatic Cholangiocarcinoma (ICC)

China
Taysha Gene Therapies, Inc.

Recruiting

Safety and Efficacy of TSHA-102 in Adult Females With Rett Syndrome (REVEAL Adult Study)

Rett Syndrome

United States, Canada
Yale University
National Institute on Drug Abuse (NIDA)

Recruiting

SV2A Density Cannabis Use Disorder

Healthy | Cannabis Use Disorder

United States
Beijing InnoCare Pharma Tech Co., Ltd.

Recruiting

A Clinical Trial of ICP-192 in Treated Patients With Advanced Solid Tumors With FGF/FGFR Gene Alterations

Advanced Solid Tumor

China
NovalGen Ltd.

Recruiting

First in Human Study of NVG-111 in Relapsed/Refractory ROR1+ Malignancies

Follicular Lymphoma | Mantle Cell Lymphoma | Diffuse Large B Cell Lymphoma | Non-small Cell Lung Cancer (NSCLC) | Small Lymphocytic Lymphoma | Malignant Melanoma | Chronic Lymphocytic Leukaemia

United Kingdom
BrainQ Technologies Ltd.
Sheba Medical Center; The Miami Project to Cure Paralysis; Kessler Institute...

Recruiting

The Use of Electromagnetic Field (EMF) Treatment in Chronic Spinal Cord Injury (SCI) Patients

Incomplete Spinal Cord Injury

Israel, United States
Rahul Parikh
Taiho Oncology, Inc.

Recruiting

A Phase II Study of Lonsurf (TAS-102) in Metastatic Platinum and Checkpoint Inhibitor-resistant Bladder Cancer

Bladder Cancer

United States
Beijing InnoCare Pharma Tech Co., Ltd.

Recruiting

Clinical Study of ICP-192 in Solid Tumors Patients

Solid Tumor

China
National Institute of Mental Health (NIMH)

Completed

Evaluation of a Novel PET Radioligand to Image Cyclooxygenase-1 (COX-1)

Normal Physiology

United States
Raziel Therapeutics Ltd.
University of Arizona

Completed

Treatment of Women With Lipedema Involving Substantial Fat Knee of Women and Men With Nodular Dercum's Disease

Dercum Disease | Lipedema

United States
Tammie L. S. Benzinger, MD, PhD

Active, not recruiting

Investigation of Inflammation Using [C-11]-CS1P1 (CS1P1)

Alzheimer Disease

United States
Takeda

Active, not recruiting

A Study of TAK-102 in Adult With Previously-Treated Solid Tumors

Solid Tumors

Japan
REGENXBIO Inc.

Active, not recruiting

RGX-121 Gene Therapy in Children 5 Years of Age and Over With MPS II (Hunter Syndrome)

Mucopolysaccharidosis Type II (MPS II)

United States, Canada
Hope Medicine (Nanjing) Co., Ltd

Completed

To Evaluate the Safety, Tolerability and Efficacy in Male and Female With AGA Treated With HMI-115 Over a 24-week Treatment Period

Androgenetic Alopecia

Australia
Taiho Oncology, Inc.

Terminated

TAS-117 in Patients With Advanced Solid Tumors Harboring Germline PTEN Mutations

Advanced or Metastatic Solid Tumors Irrespective of Gene Alterations | Advanced or Metastatic Solid Tumors With Germline PTEN Inactivating Mutations

United States, United Kingdom, Austria, France
OncoVerity, Inc.
Janssen Research & Development, LLC; argenx

Completed

A Study of ARGX-110 in Participants With Advanced Malignancies

Neoplasms

France, Belgium
Minoryx Therapeutics, S.L.

Active, not recruiting

A Clinical Study in Male Pediatric Patients With Cerebral X-linked Adrenoleukodystrophy (Cald) to Assess the Effects of MIN-102 Treatment on Disease Progression Prior to Human Stem Cell Transplant (HSCT) (NEXUS)

Cerebral Adrenoleukodystrophy

Spain, Germany, France, Argentina

Search clinical trials for: DE-112

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