Search clinical trials for: GABA Agents

Total 187517 results

Duke University
National Institute of Mental Health (NIMH)

Completed

Combined Behavioral/Pharmacological Therapy for Insomnia

Sleep Initiation and Maintenance Disorders

United States
Eli Lilly and Company

Completed

A Study of LY2624803 in Participants With Transient Insomnia

Transient Insomnia

France
Takeda

Completed

Safety of Ramelteon in Elderly Subjects

Insomnia

United States
Sanofi

Completed

Evaluation of the Hypnotic Properties of Zolpidem-MR 12.5 mg and Zolpidem 10 mg Marketed Product Compared to Placebo in Patients With Primary Insomnia

Sleep Initiation and Maintenance Disorders

United States, Canada, Australia
Marion Coe
National Institute on Drug Abuse (NIDA)

Completed

Sedative-Anxiolytic Effects on Simulated Driving Performance

Psychomotor Impairment

United States
Marinus Pharmaceuticals

Withdrawn

To Evaluate the Efficacy, Safety, and Tolerability of Intravenous Ganaxolone Added to Standard of Care in Refractory Status Epilepticus (RSE)

Refractory Status Epilepticus

Spain, Switzerland, Germany, France, Austria, Italy, Belgium, United Kingdom, Czechia, Croatia, Finland, Lithuania, Israel, Hungary, Poland, Slovakia
Marinus Pharmaceuticals

Completed

Intravenous Ganaxolone as Adjunctive Therapy to Treat Subjects With Status Epilepticus

Epilepsy | Status Epilepticus | Convulsive Status EPILEPTICUS | Non Convulsive Status Epilepticus

United States
AstraZeneca

Terminated

Efficacy and Safety of Inhaled AZD1402 Administered for Four Weeks in Adults With Asthma on Medium-to-High Dose Inhaled Corticosteroids (APATURA)

Asthma

Germany, Spain, United Kingdom, Korea, Republic of, Canada, Poland, Australia, Taiwan, Hungary, Ukraine
University of California, Davis

Terminated

Flumazenil for Hypoactive Delirium Secondary to Benzodiazepine Exposure (FLYP)

Hypoactive Delirium

United States
Seoul National University Hospital

Unknown

Therapeutic Drug Monitoring for Individualized Clozapine Therapy

Schizophrenia

Korea, Republic of
Emory University
Cephalon

Completed

Study To Evaluate The Effects Of Gabitril™ In Patients With Social Anxiety Disorder

Social Anxiety Disorder

United States
St. Joseph's Hospital and Medical Center, Phoenix
H. Lundbeck A/S

Unknown

Evaluation of Onfi Conversion Therapy Replacing Clonazepam in Patients With Medically Refractory Epilepsy

Refractory Epilepsy

United States
University Hospital, Caen

Recruiting

Clozapine and Haematologic Malignancies: Observational and Retrospective Study Using the WHO Pharmacovigilance Database (CLOZARIX)

Lymphoma | Leukemia

France
Seoul National University Bundang Hospital

Unknown

F-18 Altanserin PET Study of Patients Receiving Clozapine (APC)

Schizophrenia | Schizoaffective Disorder

Korea, Republic of
Sohaib Ashraf

Unknown

Role of Alprazolam in the Management of Acute Coronary Syndrome (A-ACS-PK)

Myocardial Infarction | Heart Diseases | ST Elevation Myocardial Infarction | Anxiety | Acute Coronary Syndrome

Pakistan
Dent Neuroscience Research Center

Withdrawn

Effect of Primidone on Platelet Responsiveness in Patients Determined to be Clopidogrel Resistant

Clopidogrel Resistance | Secondary Stroke Prevention

United States
University of California, San Francisco
US Department of Veterans Affairs

Recruiting

Treatment of Disturbed Sleep in Progressive Supranuclear Palsy (PSP)

Treatment

United States
Biolab Sanus Farmaceutica

Completed

Pharmacokinetics Study of Zolpidem Hemitartarate Orodispersible Tablet 3.5 mg Formulation

Healthy

Brazil
Biolab Sanus Farmaceutica

Completed

Pharmacokinetics Study of Zolpidem Hemitartarate Orodispersible Tablet 1.75 mg Formulation

Healthy

Brazil
Takeda

Completed

Facilitation of Zolpidem (≥10 mg) Discontinuation Through Use of Ramelteon in Subjects With Chronic Insomnia

Chronic Insomnia

United States
H. Lundbeck A/S

Completed

An Investigational Study of MK0928 in Adult Outpatients With Insomnia (0928-014)(COMPLETED)

Insomnia
Orion Corporation, Orion Pharma

Completed

Bioequivalence Study Comparing Two Alprazolam 1 mg Tablets

Healthy

Finland
Eisai Inc.

Completed

Study of the Efficacy and Safety of Lemborexant in Subjects 55 Years and Older With Insomnia Disorder (SUNRISE 1) (SUNRISE 1)

Insomnia

United States, Spain, United Kingdom, Italy, Germany, France, Canada
GlaxoSmithKline

Completed

Effects of Repeat Dosing of GSK1521498

Obesity

United Kingdom
Mutual Pharmaceutical Company, Inc.

Completed

Fed Bioequivalence Study of Zolpidem Tartrate Tablets and Ambien® Tablets

Healthy | Therapeutic Equivalency
VA Office of Research and Development

Completed

A Randomized Trial of Medical and Surgical Treatments for Patients With GERD Symptoms That Are Refractory to Proton Pump Inhibitors

GERD

United States
Impax Laboratories, LLC

Completed

A Study With IPX056 in Subjects With Spasticity Associated With Multiple Sclerosis

Multiple Sclerosis | Spasticity

United States
EMS
Associação Fundo de Incentivo à Pesquisa

Completed

Efficacy and Safety of 5 mg Sublingual Zolpidem vs 10mg Oral Zolpidem in the Induction and Maintenance of Sleep in Patients With Primary Insomnia

Primary Insomnia

Brazil
Cephalon

Completed

Study to Evaluate the Safety and Efficacy of GABITRIL Treatment in Adults With Generalized Anxiety Disorder.

Anxiety Disorders

United States, Canada
Mclean Hospital
National Institute on Drug Abuse (NIDA)

Unknown

Imaging the Effects of Zolpidem and Alprazolam in Healthy Volunteers at 3T

Psychotropic Drugs Effects

United States
All India Institute of Medical Sciences, Bhubaneswar

Completed

Comparison of Maintenance ECT Versus Clozapine in Treatment-resistant Schizophrenia

Treatment Resistant Schizophrenia

India
H. Lundbeck A/S

Completed

Safety of MK0928 on Insomnia in the Elderly (0928-005)(COMPLETED)

Insomnia
Pfizer
Investigación Farmacológica y Biofarmacéutica

Withdrawn

Triazolam Trial In Healthy Subjects To Compare Bioavailability Between Formulations Of Triazolam To Determine Their Bioequivalence In Terms Of Rate And Magnitude Of Absorption

Healthy Volunteers
H. Lundbeck A/S

Completed

Adult Primary Insomnia Polysomnographic Study (0928-004)(COMPLETED)

Primary Insomnia
Neurogen Corporation

Terminated

Efficacy and Safety Study of Adipiplon, Placebo and an Active Control in Primary Insomniacs

Primary Insomnia

United States
University of North Carolina, Chapel Hill

Completed

Combination of Naltrexone and Baclofen for Alcohol Dependence:A Pilot Study.

Alcohol Dependence
Neurona Therapeutics
California Institute for Regenerative Medicine (CIRM)

Recruiting

FIH Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy

Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis

United States
Anders Fink-Jensen, MD, DMSci
Rigshospitalet, Denmark; University of Copenhagen

Completed

The Significance of Deviation in Time From the 12-hour Standard Serum-clozapine Monitoring.

Schizophrenia

Denmark
Rijnstate Hospital

Completed

Effects of Temazepam in Patients With Chronic Pulmonary Obstructive Disease

Chronic Obstructive Pulmonary Disease

Netherlands
Marinus Pharmaceuticals

Completed

Study of Adjunctive Ganaxolone Treatment in Children and Young Adults With CDKL5 Deficiency Disorder (Marigold)

CDKL5 Deficiency Disorder

United States, Australia, France, Israel, Italy, Poland, Russian Federation, United Kingdom
XenoPort, Inc.

Completed

A Study to Evaluate the Safety and Tolerability of Arbaclofen Placarbil (XP19986) in Subjects With Acute Back Spasms

Back Pain

United States
Yale University
National Alliance for Research on Schizophrenia and Depression

Completed

GABA-glutamate Interactions and Psychosis

Cognitive Dysfunction

United States
Yao Yusheng
West China Hospital

Completed

Effects of Dexmedetomidine Premedication on Emergence Agitation After Strabismus Surgery in Children

Delirium on Emergence | Inhalational Anesthetics Adverse Reaction | Strabismus Following Ocular Surgery

China
Indivior Inc.

Completed

A Phase 1 Bioavailability Study of Arbaclofen Placarbil Modified Release Formulations in Healthy Volunteers

Healthy Volunteers

United Kingdom
Centre for Addiction and Mental Health

Recruiting

Switching From Twice-Daily to Once-Daily Clozapine Dosing in Schizophrenia

Schizophrenia | Schizoaffective Disorder

Canada
Northwell Health
National Institute of Mental Health (NIMH)

Completed

Electroconvulsive Therapy in Clozapine Refractory Schizophrenia

Schizophrenia

United States
Marinus Pharmaceuticals

Completed

Study of Adjunctive Ganaxolone Treatment in Female Children With Protocadherin 19 (PCDH19)-Related Epilepsy (Violet Study)

PCDH19-Related Epilepsy

United States, Hungary, Italy, Netherlands, Poland
Sage Therapeutics

Completed

A Study to Evaluate Safety and Efficacy of SAGE-547 in Participants With Moderate Postpartum Depression (547-PPD-202C)

Postpartum Depression

United States
Cephalon

Completed

A 10-Week Study for Efficacy and Safety Study of Gabitril in the Treatment of Adults With Generalized Anxiety Disorder

Generalized Anxiety Disorder

United States
Hadine Joffe, MD
National Institute of Mental Health (NIMH)

Completed

Estrogen for Treating Depression in Menopausal Women With Hot Flashes and Insomnia

Depression | Sleep Initiation and Maintenance Disorders

United States

Search clinical trials for: GABA Agents

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