Clinical Trials Sponsored by DAPS Health LLC

Total 678 results

Asthma Management Systems
Merck Sharp & Dohme LLC; West Penn Allegheny Health System

Completed

Improving Asthma Control in the Real World: A Systematic Approach to Improving Dulera Adherence

Asthma

United States
University of Virginia
Merck Sharp & Dohme LLC; National Institutes of Health (NIH)

Completed

Growth Hormone Secretagogue MK-0677 Effect on IGF-1 Levels in ESRD Patients

End Stage Renal Disease | Chronic Kidney Disease

United States
Cyprus International Institute for Environment...
Merck Sharp & Dohme LLC

Completed

The Relation Between Obesity, Adipose Tissue Content of Fatty Acids and Systemic and Airway Inflammation

Asthma, Allergies and Obesity

Cyprus
Main Line Health
Merck Sharp & Dohme LLC; Drexel University College of Medicine

Unknown

Oral Aprepitant and Lower Dose Dexamethasone Versus Aprepitant Alone for Preventing Postoperative Nausea and Vomiting (PONV) After Elective Laparoscopic Surgeries

Nausea | Vomiting

United States
Wake Forest University Health Sciences
Merck Sharp & Dohme LLC; G1 Therapeutics, Inc.

Recruiting

Phase II Trial of Trilaciclib, Pembrolizumab, Gemcitabine and Carboplatin in Metastatic Triple-Negative Breast Cancer (ToPCourT)

Metastatic Triple-Negative Breast Cancer

United States
The University of Texas Health Science Center,...
Merck Sharp & Dohme LLC

Completed

Exploring the Perspectives and Experiences of PrEP-eligible Black Women in Texas in Relation to Readiness for PrEP Uptake and Adherence

PrEP Uptake Perspectives | PrEP Uptake Experiences | PrEP Adherence Perspectives | PrEP Adherence Experiences

United States
Institut Bergonié
Merck Sharp & Dohme LLC; Ministry of Health, France; Immune Design

Active, not recruiting

Combination of MK3475 and Metronomic Cyclophosphamide in Patients With Advanced Sarcomas : Multicentre Phase II Trial (PEMBROSARC)

Sarcoma

France
ANRS, Emerging Infectious Diseases
Merck Sharp & Dohme LLC; Ministry of Health, Brazil

Completed

Raltegravir Versus Efavirenz in Naive HIV-1-infected Patients Receiving Rifampin for Active Tuberculosis (REFLATE TB2)

Tuberculosis | HIV-1 Infection

France, Vietnam, Brazil, Côte D'Ivoire, Mozambique
The University of Texas Health Science Center,...
Merck Sharp & Dohme LLC

Completed

Raltegravir vs. Atazanavir in Combination With Truvada® for the Treatment of Antiretroviral naïve HIV Infected Patients (RAN)

HIV Infections

United States
Oregon Health and Science University
Eli Lilly and Company; Amylin Pharmaceuticals, LLC.

Completed

How Glargine Insulin, Oral Diabetes Medications and Exenatide May Improve Blood Sugar Control and Weight Gain in Type 2 Diabetics (MEXELIN)

Type 2 Diabetes

United States
The University of Texas Health Science Center,...
North American Rescue, LLC

Terminated

Effectiveness Study of the BOA(R)-Constricting IV Band

Catheterization, Peripheral

United States
Heart Rhythm Clinical and Research Solutions, LLC
Attune Medical

Not yet recruiting

REView of ProcEdural FactoRs and Outcomes After Atrial Fibrillation Ablation With Active Esophageal COOLing: A Sub-Study of the REAL AF Registry (EVERCOOL AF)

Atrial Fibrillation
Bleep, LLC
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Sleep Apnea Study in Adults Using DreamPort-Eclipse and a Traditional Nasal Mask

Obstructive Sleep Apnea

United States
Xemed LLC
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health... and other collaborators

Completed

MagniXene MRI Use in Patients With Asthma and COPD to Assess Regional Lung Function by Delineating Ventilation Defects (HXe-VENT)

Healthy | Asthma | COPD

United States
Volta Medical
Heart Rhythm Clinical and Research Solutions, LLC

Recruiting

Clinical and Healthcare Outcomes From Real-World Use in the United States of a Companion AI During AF Ablation (COMPANION AI)

Atrial Fibrillation

United States
Bleep, LLC
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Simulated In-House Usability Study of Eclipse Continuous Positive Airway Pressure (CPAP) Device

Obstructive Sleep Apnea

United States
DVX, LLC
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Cost-Effectiveness of a Specialized Ultrasound Instrument to Diagnose Carotid Stenosis as a Way to Reduce the Risk of Stroke

Carotid Stenosis | Cerebrovascular Accident

United States
Bleep, LLC
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Field Usability Study of Eclipse Mask

Obstructive Sleep Apnea

United States
MedImmune LLC
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effect of ACP-501 on Safety, Tolerability, Pharmacokinetics and Pharmacodynamics in Subjects With Coronary Artery Disease

Coronary Artery Disease | Atherosclerosis

United States
Gmax Biopharm Australia Pty Ltd.
Metaclinical; Syneos Heath

Completed

A Study to Investigate Safe and Tolerable Dose of GMA301 Injection in Healthy Volunteers

Pulmonary Arterial Hypertension

Australia
LMC Diabetes & Endocrinology Ltd.
Bausch Health Americas, Inc.

Completed

Randomized Trial Comparing Colesevelam vs. Ezetimibe (GOAL-RCT)

Type 2 Diabetes Mellitus

Canada
Stuart Mazzone
Melbourne Health; Merck Sharp & Dohme LLC; Monash University

Recruiting

Effect of Gefapixant on Cough-related Brain Activity in Patients With Chronic Cough

Chronic Cough

Australia
University Health Network, Toronto
Merck Sharp & Dohme LLC; ImmunoVaccine Technologies, Inc. (IMV Inc.)

Active, not recruiting

Phase 2 Study of Pembrolizumab, DPX-Survivac Vaccine and Cyclophosphamide in Advanced Ovarian, Primary Peritoneal or Fallopian Tube Cancer

Ovarian Cancer | Fallopian Tube Cancer | Advanced Cancer | Primary Peritoneal Carcinoma

Canada
The Center for Applied Health Sciences, LLC
Mend Nutrition, Inc; Keller Consulting Group

Completed

Effects of a Dietary Supplement on Markers of Glucose Control and Quality of Life

Blood Glucose

United States
National Opinion Research Center
Merck Sharp & Dohme LLC; Emory University; Grady Health System

Terminated

Registry-based HCV Care Cascade Navigation at Atlanta's Grady Memorial Hospital (EZ-C)

Hepatitis C

United States
Merck Sharp & Dohme LLC
Department of Health and Human Services; BioProtection Systems Corporation

Completed

Placebo Controlled, Dose Response, Safety and Immunogenicity Study of Vesicular Stomatitis Virus (VSV) Ebola Vaccine in Healthy Adults (V920-004)

Ebola Virus
Astellas Pharma Europe B.V.
World Health Information Science Consultants, LLC

Completed

Short and Long-term Safety of Micafungin and Other Parenteral Antifungal Agents (MYCOS)

Systemic Fungal Infections

United States
Indiana Nanotech, LLC
The University of Texas Health Science Center at San Antonio

Completed

Evaluation of a Low-fluoride Anticaries Toothpaste

Tooth Abnormality

United States
University of Calgary
Merck Sharp & Dohme LLC; Canadian Institutes of Health Research (CIHR)

Completed

Paroxysmal Atrial Fibrillation: Role of Inflammation, Oxidative Stress Injury and Effect of Statins (PAFRIOSIES)

Atrial Fibrillation

Canada
Integrated Medical Research LLC
New York State Department of Health; Alere San Diego

Completed

Improving the Management of Acute Coronary Syndromes in the Emergency Department (RACE)

Acute Coronary Syndrome

United States
University Health Network, Toronto
Patient-Centered Outcomes Research Institute; M.D. Anderson Cancer Center; Applied... and other collaborators

Active, not recruiting

PRO-ACTIVE: Prophylactic Swallow Intervention for Patients Receiving Radiotherapy for Head and Neck Cancer (PRO-ACTIVE)

Dysphagia

United States, Canada
University of Ulster
Merck Sharp & Dohme LLC; Northern Health and Social Care Trust

Not yet recruiting

The Impact of the Establishment of a New AMS CPS in a Rural Hospital in Austria

Antimicrobial Stewardship
Louisiana State University Health Sciences Center...
Merck Sharp & Dohme LLC

Recruiting

Immunogenicity of Gardasil-9 HPV Vaccine in People Living With HIV (AGO-Gard)

Cervical Intraepithelial Neoplasia | Human Immunodeficiency Virus | Anal Intraepithelial Neoplasia | Papillomavirus Infection | Papillomavirus Vaccines | Serology | Oral Cavity Infection

United States
Sunnybrook Health Sciences Centre
Merck Sharp & Dohme LLC; ImmunoVaccine Technologies, Inc. (IMV Inc.)

Completed

DPX-Survivac and Checkpoint Inhibitor in DLBCL (SPiReL)

Recurrent | Adult Diffuse Large Cell Lymphoma | Adult Refractory Diffuse Large B-Cell Lymphoma

Canada
Actelion
Henry Ford Health System; Covance; Medidata Solutions; Almac Clinical Technologies and other collaborators

Terminated

An Upcoming Clinical Study to Measure the Safety and Impact of a Drug Called Macitentan in Teenage and Adult Fontan Patients. (RUBATO OL)

Congenital Heart Disease With Fontan Circulation

United Kingdom, Taiwan, France, Poland, China, Australia, Czechia, Canada, United States, Denmark, New Zealand
Velindre NHS Trust
AstraZeneca; Cardiff and Vale University Health Board; Covance; Cenduit LLC

Active, not recruiting

Fulvestrant +/- Akt Inhibition in Advanced Aromatase Inhibitor Resistant Breast Cancer (FAKTION)

Estrogen Receptor Positive Breast Cancer

United Kingdom
OHSU Knight Cancer Institute
Merck Sharp & Dohme LLC; Oregon Health and Science University

Terminated

Pembrolizumab and Magnetic Resonance Imaging With Ferumoxytol in Treating Patients With Non-small Cell Lung Cancer and Brain Metastases

Stage IV Lung Non-Small Cell Cancer AJCC v7 | Lung Carcinoma Metastatic in the Brain

United States
NYU Langone Health
National Institute on Drug Abuse (NIDA); The Emmes Company, LLC

Completed

Extended-Release Naltrexone vs. Buprenorphine for Opioid Treatment

Opioid Use Disorder

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI); Merck Sharp & Dohme LLC

Completed

Aprepitant in Preventing Nausea and Vomiting in Patients Undergoing Chemotherapy and Radiation Therapy for Pancreatic Cancer

Nausea | Vomiting | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Extrahepatic Bile Duct Cancer | Stage II Pancreatic Cancer

United States
The University of Texas Health Science Center at...
Amylin Pharmaceuticals, LLC.

Completed

Acute Effect of Exenatide on Brain Glucose Metabolism

Diabetes | Impaired Glucose Tolerance (IGT)

United States
OHSU Knight Cancer Institute
Janssen Scientific Affairs, LLC; Oregon Health and Science University

Active, not recruiting

Advanced ChemoHormonal Therapy for Treatment Naive Metastatic Prostate Cancer

Metastatic Prostate Carcinoma | Stage IVB Prostate Cancer AJCC v8 | Castration-Sensitive Prostate Carcinoma

United States
Providence Health & Services
MedImmune LLC; Providence Cancer Center, Earle A. Chiles Research Institute

Active, not recruiting

Study of MEDI0562 Prior to Surgical Resection in Head and Neck Squamous Cell Carcinoma (HNSCC) or Melanoma

Melanoma | Head and Neck Cancer | Carcinoma, Squamous Cell | Head and Neck Squamous Cell Carcinoma | Cell Cancer, Squamous

United States
Spectrum Health Hospitals
Blue Care Network of Michigan; We Are For Children, LLC

Completed

Evaluation of a Primary Care Weight Management Program in Children Aged 2 to 5 Years

Physical Activity | Childhood Obesity | Feeding Behavior
University of Maryland, Baltimore
Merck Sharp & Dohme LLC; National Institutes of Health (NIH)

Completed

Cardiovascular Disease in HIV and Hepatitis C: Risk Outcomes After Hepatitis C Eradication (CHROME)

Cardiovascular Diseases | Hepatitis C | Hiv

United States
Indiana Nanotech, LLC
The University of Texas Health Science Center at San Antonio

Completed

Development and Validation of a Multi-Mineral Fluoride Mouthrinse

Dental Caries

United States
Boston Children's Hospital
Merck Sharp & Dohme LLC; Harvard School of Public Health (HSPH)

Completed

Immunogenicity to Human Papillomavirus Vaccine (Gardasil) Among IBD Patients on Immunosuppressive Therapy (HPV)

Inflammatory Bowel Disease

United States
Stanford University
National Institute on Minority Health and Health Disparities (NIMHD); Ohio... and other collaborators

Not yet recruiting

Implementing Scalable, PAtient-centered Team-based Care for Adults With Type 2 Diabetes and Health Disparities (iPATH) (iPATH)

Diabetes Mellitus, Type 2

United States, Puerto Rico
Thomas Schricker
Merck Sharp & Dohme LLC

Terminated

Surgical Conditions During Vocal Cord Surgery Requiring Jet Ventilation With Moderate vs. Deep Neuromuscular Block

High-Frequency Jet Ventilation | Vocal Cord Resection

Canada
Liverpool Heart and Chest Hospital NHS Foundation...
Biolife LLC

Not yet recruiting

Statseal® for Central Venous Catheter Insertion Sites in Critical Care (SCENIC)

Vascular Access | Critical Care | Central Venous Catheter | Central Line | Hemostatic

United Kingdom
Heart Rhythm Clinical and Research Solutions, LLC
Biosense Webster, Inc.

Recruiting

The Long-term Safety and Effectiveness Evaluation of the QDOT MICRO System Use in Conjunction With VISITAG SURPOINT Module for the Treatment of Symptomatic Drug Refractory Paroxysmal Atrial Fibrillation. (QDOT PAS)

Paroxysmal Atrial Fibrillation

United States

Clinical Trials Sponsored by DAPS Health LLC

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