Clinical Trials Sponsored by Leading BioSciences, Inc

Total 762 results

Coherus Biosciences, Inc.

Completed

Assessing the Immunogenicity of 2 Subcutaneous Doses of CHS-1701 (Coherus Pegfilgrastim) With 2 Subcutaneous Doses Neulasta®

Immunity, Humoral

United States
Coherus Biosciences, Inc.

Completed

Comparison of the Pharmacokinetic and Pharmacodynamic Biosimilarity of CHS-1701 (Coherus Pegfilgrastim) With Neulasta® (Pegfilgrastim)

Bioequivalence

United States
Coronado Biosciences, Inc.

Withdrawn

TSO for Plaque Psoriasis

Plaque Psoriasis
LegoChem Biosciences, Inc

Completed

Multiple Ascending Dose Study for LCB01-0371

Healthy

Korea, Republic of
Ardea Biosciences, Inc.

Completed

Bioavailability of Lesinurad and Intravenous [14C]Lesinurad

Healthy

United States
Ardea Biosciences, Inc.

Completed

Antacid Interaction Study

Healthy

United States
Aptose Biosciences Inc.

Completed

A Study of LOR-253 HCl in Patients With Advanced or Metastatic Solid Tumours

Advanced or Metastatic Solid Tumours

United States
Cellectar Biosciences, Inc.

Withdrawn

Open-Label Study of I-131-CLR1404 in Subjects With Recurrent Glioma

Glioma

United States
Ardea Biosciences, Inc.

Completed

Metformin and Furosemide Drug-Drug Interaction Study

Healthy

United States
Ardea Biosciences, Inc.

Completed

Single and Multiple Dose Study in Japanese Subjects

Gout

United States
Ardea Biosciences, Inc.

Completed

Single and Multiple Dose Study in Japanese

Gout

United States
Coronado Biosciences, Inc.

Completed

Safety and Tolerability of Single Doses Oral CNDO 201 Trichuris Suis Ova in Patients With Crohn's Disease

Crohn's Disease

United States
Lux Biosciences, Inc.

Completed

A Multi-center Study to Assess the Efficacy and Safety of LX211 in Active Non-infectious Anterior Uveitis (LUMINATE)

Uveitis, Anterior | Panuveitis

United Kingdom, Canada, United States, Germany, Austria, France, India
Lux Biosciences, Inc.

Completed

A Dose-Escalation Study to Assess the Safety and Tolerability of LX214 Ophthalmic Solution in Healthy Volunteers, Followed by an Open-Label Evaluation of LX214 in Patients With Keratoconjunctivitis Sicca (KCS)

Keratoconjunctivitis Sicca

United States
Lux Biosciences, Inc.

Completed

A Study of LX211 in Clinically Quiescent Non-infectious Intermediate, Anterior and Intermediate, Posterior or Pan-Uveitis (LUMINATE)

Panuveitis | Uveitis, Posterior | Uveitis, Intermediate

United States, United Kingdom, Canada, Germany, Austria, France, India
FerroKin BioSciences, Inc.

Completed

Safety and Pharmacokinetic Study of Escalating Multiple Doses of an Iron Chelator in Patients With Iron Overload

Beta-thalassemia | Transfusional Iron Overload

United States, Australia, Thailand
Aptose Biosciences Inc.

Completed

A Study to Test the Effectiveness of Virulizin® Given in Combination With Standard Chemotherapy for Pancreatic Cancer

Pancreatic Cancer
Shanghai Junshi Bioscience Co., Ltd.
Iqvia Pty Ltd; TopAlliance Biosciences, Inc.

Active, not recruiting

Safety, Tolerability and Pharmacokinetics of an Anti-PD-1 Monoclonal Antibody in Subjects With Advanced Malignancies

Advanced Malignancies

United States
University of Utah
Abbott; Leadiant Biosciences, Inc.; Families of Spinal Muscular Atrophy

Completed

Study of Safety and Dosing Effect on SMN Levels of Valproic Acid (VPA) in Patients With Spinal Muscular Atrophy

Spinal Muscular Atrophy

United States
University of Utah
Abbott; Leadiant Biosciences, Inc.; Families of Spinal Muscular Atrophy

Completed

Valproic Acid and Carnitine in Patients With Spinal Muscular Atrophy

Spinal Muscular Atrophy

United States, Canada
Cogent Biosciences, Inc.
Seagen Inc.

Terminated

Study of ACTR087 in Combination With SEA-BCMA in Subjects With Relapsed or Refractory Multiple Myeloma

Multiple Myeloma | Refractory Multiple Myeloma | Multiple Myeloma in Relapse

United States
Deacon Biosciences, Inc.
ORA, Inc.

Completed

A Phase 2, Open-Label, Randomized, Parallel Group, Placebo-Controlled, Single-Center Study to Assess Anti-microbial Efficacy and Safety of DCN01 Compared to Unisol® Following Topical Periocular Administration in Healthy Volunteers

Ocular Infection

United States
University of Reading
Polyphenolics, Inc.

Completed

Investigation of the Acute and Chronic Cognitive and Mood Effects of CP9700 in Humans

Cognitive Function | Mood

United Kingdom
Lumen Bioscience, Inc.

Not yet recruiting

Etiology of Travelers' Diarrhea in Australian Tourists Traveling to Southeast Asia (AusTD)

Travelers Diarrhea
Txinno Bioscience Inc.

Recruiting

A Study of TXN10128 in Subjects With Solid Tumors

Locally Advanced (Unresectable) or Metastatic Solid Tumors

Korea, Republic of
Aadi Bioscience, Inc.

Recruiting

Dose-escalation Study to Assess Safety and Pharmacokinetics of Nab-Sirolimus in Patients With Locally Advanced or Metastatic Solid Tumors and Moderate Liver Impairment

Advanced Solid Tumor | Tumor | Tumor, Solid

United States
Intima Bioscience, Inc.

Not yet recruiting

CISH Inactivated TILs in the Treatment of NSCLC (CheckCell-2)

Carcinoma, Non-Small-Cell Lung | Adenocarcinoma of Lung | Stage IV Non-small Cell Lung Cancer | Squamous Cell Lung Cancer | Metastatic Non Small Cell Lung Cancer | Large Cell Lung Cancer

United States
Cothera Bioscience, Inc

Recruiting

Sepantronium Bromide for the Treatment of High-grade B-cell Lymphoma

Lymphoma, B-Cell | Lymphoma, Large B-Cell, Diffuse | Lymphatic Diseases | Burkitt Lymphoma | High-grade B-cell Lymphoma | C-MYC/BCL6 Double-Hit High-Grade B-Cell Lymphoma | C-MYC/BCL2 Double-Hit High-Grade B-Cell Lymphoma | Lymphoma, High-Grade | C-Myc Gene Rearrangement

Korea, Republic of, China
Aadi Bioscience, Inc.

Active, not recruiting

Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes (PRECISION 1)

Malignant Solid Neoplasm | Neoplasms | Cancer | Neoplasm Metastasis | Solid Tumor | Metastatic Cancer | Metastasis | Advanced Solid Tumor | Metastatic Solid Tumor | Advanced Cancer | Tumor | Malignant Neoplasm | Malignant Tumor | Tumors | Cancer Metastatic | Tumor, Solid | Malignant Solid Tumor | TSC | TSC1 | TSC2 | Metastatic Neoplasm

United States, Korea, Republic of, Puerto Rico
Blaze Bioscience Inc.

Available

Expanded Access for BLZ-100 (Tozuleristide)
Skye Bioscience, Inc.

Completed

Phase 2, Placebo-Controlled, Study Assessing the Safety and Ocular Efficacy of SBI-100 Ophthalmic Emulsion in Patients With Elevated Eye Pressure

Primary Open Angle Glaucoma | Ocular Hypertension

United States
Aadi Bioscience, Inc.

Completed

Nab-Sirolimus in Combination With FOLFOX & BEV as 1st Line Therapy in Patients With Advanced or Metastatic Colorectal Cancer

Colorectal Cancer Metastatic

United States
Daré Bioscience, Inc.

Completed

Study of Intravaginal Tamoxifen in PostMenopausal Women With VVA (DARE-VVA1)

Vulvar Atrophy

Australia
Meridian Bioscience, Inc.

Completed

BreathID 13C-Methacetin Breath Test for Detecting Cirrhosis (MBT)

Chronic Liver Disease

United States, Israel
Meridian Bioscience, Inc.

Completed

BREATHID Octanoate Breath Test With or Without Methacetin Breath Test for Correlation With Biopsy in NASH

Non-Alcoholic Steatohepatitis

United States, France, Belgium, United Kingdom
Meridian Bioscience, Inc.

Completed

Determination of HCC With Octanoate Breath Test vs. MRI Diagnosis

Hepatocellular Carcinoma (HCC)

China
Meridian Bioscience, Inc.

Completed

Prediction Value of the BreathID 13C-Methacetin Breath Test for Hepatic Decompensation

Chronic Liver Disease

United States, Israel
Meridian Bioscience, Inc.

Completed

Exalenz Lab Mode System Compared to Biopsy for H.Pylori Detection

Helicobacter Pylori Infection

United States, Israel
Meridian Bioscience, Inc.

Completed

Show Equivalence of the Modified BreathID Compared to Currently Approved BreathID in H.Pylori Detection

Suspicion of Being Infected With H.Pylori

United States
Meridian Bioscience, Inc.

Completed

Urea Breath Test (UBT) With Breath Hp System /BreathID Hp Lab System Pediatrics

Helicobacter Pylori Infection

United States, Israel
Daré Bioscience, Inc.

Completed

DARE-BV1 in the Treatment of Bacterial Vaginosis (DARE-BVFREE)

Bacterial Vaginosis

United States
Daré Bioscience, Inc.

Completed

Pharmacokinetic Study of DARE-BV1

Bacterial Vaginosis

United States
Lumen Bioscience, Inc.

Completed

Exploratory Study to Assess Delivery of LMN-201 Components Via Enteric Capsules in the Gut of Individuals With Ostomies

C. Diff. Infections

Australia
INVO Bioscience, Inc.

Active, not recruiting

3 Year Retrospective Analysis of IVF in Comparison With INVOcell

Infertility

United States
ICON Bioscience Inc

Terminated

Efficacy and Safety Study of IBI-10090 in Patients Undergoing Cataract Surgery

Inflammatory Reaction Due to Ocular Lens Prosthesis

United States
ICON Bioscience Inc

Completed

Study to Evaluate the Safety for the Treatment of Inflammation Associated With Cataract Surgery

Cataract

United States
ICON Bioscience Inc

Completed

The Efficacy and Safety of IBI-10090 for the Treatment of Inflammation Associated With Cataract Surgery

Inflammation | Cataracts

United States
Blaze Bioscience Inc.

Completed

Exploratory Study of Safety and ex Vivo Fluorescence of BLZ-100 in Adult Subjects With Solid Tumors Undergoing Surgery

Tumors, Breast

United States
Perle Bioscience, Inc.

Withdrawn

The Insulin Independence Trial (IIT) Evaluating the Safety and Efficacy of Oral Cyclosporine and Oral Lansoprazole for Insulin Independence Among Patients With Existing Type 1 Diabetes (IIT)

Type 1 Diabetes
Meridian Bioscience, Inc.

Completed

Detection of Mycoplasma Pneumoniae

Mycoplasma Pneumoniae

United States

Clinical Trials Sponsored by Leading BioSciences, Inc

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