Clinical Trials Sponsored by Orphan Australia

Total 1660 results

Terran Biosciences Australia Pty Ltd

Recruiting

A Study of Idazoxan in Healthy Participants

Healthy

Australia
Alphamab (Australia) Co Pty Ltd.

Recruiting

First-In-Human Study in Subjects With Advanced or Metastatic Solid Malignant Tumors

Advanced Solid Tumors | Metastatic Solid Tumors

Australia
PureTech
Novotech (Australia) Pty Limited

Recruiting

LYT-300 in Healthy Volunteers

Healthy Volunteers

Australia
Princess Alexandra Hospital, Brisbane, Australia

Recruiting

The CARMA Technique Study

Colonic Polyp | Colonic Sessile Serrated Lesion

Australia
Peter MacCallum Cancer Centre, Australia

Recruiting

Hepatocellular Carcinoma Imaging Using PSMA PET/CT (HepaSMART)

Hepatocellular Carcinoma

Australia
Akesobio Australia Pty Ltd

Recruiting

A Study to Evaluate the Safety, Pharmacokinetics, and Antitumor Activity of AK127 in Combination With AK104 in Advanced and Metastatic Solid Tumours

Advanced or Metastatic Solid Tumours

Australia
Center for Eye Research Australia

Recruiting

Project AMD: Comprehensive Characterisation of Age-Related Macular Degeneration and Its Progression (Project AMD)

Age-related Macular Degeneration | Geographic Atrophy | Age Related Macular Degeneration | AMD

Australia
Peter MacCallum Cancer Centre, Australia

Recruiting

Study of Lenalidomide, Venetoclax and Obinutuzumab in Patients With Treatment-Naïve Follicular Lymphoma (LEVERAGE)

Follicular Lymphoma

United States, Australia
PureTech
Novotech (Australia) Pty Limited

Terminated

LYT-100 in Patients With BCRL

Lymphoedema | Breast Cancer Related Lymphoedema

United States, Australia
Peter MacCallum Cancer Centre, Australia

Suspended

Pidnarulex and Talazoparib in Patients With Metastatic Castration Resistant Prostate Cancer (REPAIR)

Metastatic Castration Resistant Prostate Cancer (mCRPC)

Australia
Peter MacCallum Cancer Centre, Australia

Active, not recruiting

A Phase II Study to Determine Pembrolizumab as Frontline Treatment of Patients With Hodgkin Lymphoma (PLIMATH)

Hodgkin Lymphoma

Australia, New Zealand
Peter MacCallum Cancer Centre, Australia

Active, not recruiting

ABT-199 & Ibrutinib in Mantle Cell Lymphoma (AIM) (AIM)

Mantle Cell Lymphoma

Australia
Peter MacCallum Cancer Centre, Australia

Completed

Stereotactic Radiotherapy and Anti-PD1 Antibody (Pembrolizumab) for Oligometastatic Renal Tumours (RAPPORT)

Renal Cell Carcinoma

Australia
Peter MacCallum Cancer Centre, Australia

Completed

MYPHISMO: MYB and PD-1 Immunotherapies Against Multiple Oncologies Trial (MYPHISMO)

Adenoid Cystic Carcinoma | Colorectal Cancer

Australia
Akesobio Australia Pty Ltd

Completed

A Study to Evaluate the Safety, Pharmacokinetics, and Antitumor Activity of AK117 as Monotherapy or in Combination With AK104

Neoplasms Malignant

Australia
Akesobio Australia Pty Ltd

Completed

A Study of AK120 (IL-4Rα) in Healthy Subjects and Subjects With Moderate- to- Severe Atopic Dermatitis

Atopic Dermatitis

New Zealand, Australia
Princess Alexandra Hospital, Brisbane, Australia

Completed

Comparing the Diagnostic Adequacy of 25-gauge Fork-tip, Franseen and Reverse-bevel Type Needles in Endoscopic Ultrasound Guided Tissue Acquisition

Biopsy, Needle

Australia
KoBioLabs
Novotech (Australia) Pty Limited

Completed

A Study of Single and Multiple Ascending Doses of KBL697 in Healthy Subjects

Atopic Dermatitis (AD)

Australia
ResMed
St George Hospital, Australia

Completed

Portable Oxygen Concentrator Signal Capture Study

Hypoxia

Australia
University of New England, Australia

Terminated

Analysis of Local and Circulating Compounds Released Following Blood Pressure Cuff Inflation

Ischemia

Australia
University of New England, Australia

Completed

Isometric Handgrip Exercise for Blood Pressure Management

Hypertension

Australia
Innocare Pharma Australia Pty Ltd

Completed

A Phase I Study of ICP-022 in Healthy Subjects

Rheumatoid Arthritis | Systemic Lupus Erythematosus

Australia
Alphamab (Australia) Co Pty Ltd.

Unknown

Study of the Safety, Tolerability, Pharmacokinetics, Immunogenicity and Antitumor Activity of KN046 in Subjects With Advanced Solid Tumors

Advanced Solid Tumors

Australia
Peter MacCallum Cancer Centre, Australia

Completed

A Pilot Study of Focal Ablative STereotactic RAdiosurgery for Cancers of the Kidney or Isolated Adrenal Metastases (FASTRACK)

Cancer

Australia
Blaze Bioscience Australia Pty Ltd

Completed

Safety Study of a Fluorescent Marker to Visualize Cancer Cells

Skin Neoplasms

Australia
Northside Clinic, Australia
Wesley Mission

Completed

Ketamine as an Anaesthetic Agent in Electroconvulsive Therapy (ECT)

Major Depressive Episode

Australia
Princess Alexandra Hospital, Brisbane, Australia

Completed

Cryotherapy Intervention for Docetaxel-induced Nail Toxicities

Effects of Chemotherapy

Australia
Peter MacCallum Cancer Centre, Australia

Unknown

Safety Study of Anti LewisY Chimeric Antigen Receptor in Myeloma, Acute Myeloid Leukemia or Myelodysplastic Syndrome

Multiple Myeloma | Myelodysplastic Syndrome | Acute Myeloid Leukaemia

Australia
The University of Western Australia

Completed

Regulation of Lipoprotein Metabolism in Obese Men

Obesity | Insulin Resistance | Dyslipidemia

Australia
Columbia University
FDA Office of Orphan Products Development

Recruiting

Hypoparathyroidism Natural History (SHINE)

Hypoparathyroidism

United States
Assistance Publique - Hôpitaux de Paris
Swedish Orphan Biovitrum

Recruiting

A Trial Comparing the Efficacy and Safety of Anakinra Versus Intravenous Immunoglobulin (IVIG) Retreatment, in Patients With Kawasaki Disease Who Failed to Respond to Initial Standard IVIG Treatment (ANACOMP)

Kawasaki Disease

France
Memorial Sloan Kettering Cancer Center
Swedish Orphan Biovitrum

Active, not recruiting

Palifermin With Leuprolide Acetate for the Promotion of Immune Recovery Following Total Body Irradiation Based T-Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation

Leukemia | Multiple Myeloma | Non-Hodgkin's Lymphoma | Myelodysplastic Syndrome

United States
Swedish Orphan Biovitrum
Light Chain Bioscience - Novimmune SA

Terminated

A Study to Evaluate the Efficacy, Safety and Pharmacokinetics of Emapalumab in Adult Patients With HLH

Hemophagocytic Lymphohistiocytoses

United States
FDA Office of Orphan Products Development
Centocor, Inc.

Completed

Phase III Randomized Study of Anti-Tumor Necrosis Factor Chimeric Monoclonal Antibody (cA2) for Patients With Enterocutaneous Fistulae as a Complication of Crohn's Disease

Crohn's Disease
Emory University

Completed

Phase II Study of Carmustine, Streptozocin, and Mercaptopurine for Refractory or Recurrent Brain Neoplasms

Glioblastoma Multiforme | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Recurrent Brain Tumor | Mixed Gliomas
Mayo Clinic

Completed

Study of Muromonab-CD3 and Cyclosporine in Patients With Giant Cell Myocarditis

Myocarditis

United States
Cellegy Pharmaceuticals

Completed

Phase III Study of Monolaurin Cream Therapy for Patients With Congenital Ichthyosis

Ichthyosis
FDA Office of Orphan Products Development
SciClone Pharmaceuticals

Completed

Phase I Randomized Study of CPX for the Treatment of Adult Patients With Mild Cystic Fibrosis

Cystic Fibrosis
United Therapeutics

Completed

Phase III Randomized Study of UT-15 in Patients With Primary Pulmonary Hypertension

Pulmonary Hypertension

United States
Kirby Institute
Government of Western Australia, Department of Health; Western Australia AIDS...

Completed

Western Australian Pre-exposure Prophylaxis for HIV Implementation Trial (PrEPIT-WA)

HIV Prevention

Australia
Australian and New Zealand Intensive Care Research...
National Health and Medical Research Council, Australia; Monash University; Australian...

Completed

Erythropoietin in Traumatic Brain Injury (EPO-TBI) (EPO-TBI)

Traumatic Brain Injury

Australia, Finland, Ireland, New Zealand, France, Germany, Saudi Arabia
Boston Children's Hospital
FDA Office of Orphan Products Development

Active, not recruiting

Abatacept as GVHD Prophylaxis Phase 2

Graft vs Host Disease | Malignancy

United States, Canada
Jupiter Orphan Therapeutics Inc.
National Institute on Aging (NIA)

Completed

JOTROL PK, Safety, and Food Effect Assessment

Pharmacokinetics | Food-drug Interaction | Safety

United States
Aegerion Pharmaceuticals, Inc.
FDA Office of Orphan Products Development

Completed

A Safety and Efficacy Study of AEGR-733 to Treat Homozygous Familial Hypercholesterolemia (FH)

Homozygous Familial Hypercholesterolemia

United States, Canada, Italy, South Africa
University of Chicago

Completed

Leuprolide in Determining the Cause of Gonadotropin Deficiency

Hypogonadism

United States
University of Florida

Completed

Prevention of Dichloroacetate Toxicity

Chronic Disease | Acidosis, Lactic

United States
National Jewish Health

Completed

Phase II Study of Amithiozone (Thiacetazone) for Patients With Mycobacterium Avium Complex Pulmonary Disease

Mycobacterium Avium-intracellulare Infection
Johns Hopkins University

Completed

Intraventricular Rt-PA in Patients With Intraventricular Hemorrhage

Cerebral Hemorrhage

United States
University of Michigan

Completed

Recombinant Human Keratinocyte Growth Factor in Unrelated and Related Transplants

Graft Versus Host Disease

United States
University of Texas

Terminated

Randomized Study of Intravenous Immunoglobulin in Patients With Mild or Moderate Myasthenia Gravis

Myasthenia Gravis

Clinical Trials Sponsored by Orphan Australia

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