Clinical Trials Sponsored by Royal National Orthopaedic Hospital NHS Trust

Total 624 results

Royal Devon and Exeter NHS Foundation Trust
King's College London; King's College Hospital NHS Trust; Newcastle University; Newcastle-upon-Tyne Hospitals NHS Trust and other collaborators

Completed

PROMASTER - PROspective Cohort MRC ABPI STratification and Extreme Response Mechanism in Diabetes (PROMASTER)

Diabetes

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
Cardiff and Vale University Health Board; Royal Devon and Exeter NHS Foundation...

Completed

Post-Radioiodine Graves' Management: The PRAGMA-Study (PRAGMA)

Graves' Disease

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
National Institute for Health Research, United Kingdom

Completed

Improving Outcome Measures For Adult CF ACT Trials

Cystic Fibrosis

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
National Institute for Health Research, United Kingdom

Completed

Responsiveness and MID of 4 Metre Gait Speed in Idiopathic Pulmonary Fibrosis (IPFRESP)

Idiopathic Pulmonary Fibrosis

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
National Institute for Health Research, United Kingdom

Completed

The Predictive Ability of 4MGS in IPF (IPFMORT)

Idiopathic Pulmonary Fibrosis

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
National Institute for Health Research, United Kingdom

Recruiting

Spirometry Interpretation Performance of Primary Care Clinicians With/Without AI Software (SPIRO-AID)

Lung Disease

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
National Institute for Health Research, United Kingdom

Completed

Reliability of the 4 Metre Gait Speed in Idiopathic Pulmonary Fibrosis (IPFREL)

Idiopathic Pulmonary Fibrosis

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
National Institute for Health Research, United Kingdom

Completed

Implementation of Telemonitoring in Chronic Heart or Lung Failure (TELECRAFT)

Heart Failure | Respiratory Failure | COPD

United Kingdom
King's College London
King's College Hospital NHS Trust; Juvenile Diabetes Research Foundation; Guy... and other collaborators

Completed

Hypoglycaemia Awareness Restoration Programme (HARPdoc)

Hypoglycemia | Type 1 Diabetes Mellitus

United States, United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
National Institute for Health Research, United Kingdom

Active, not recruiting

AI in PRImary Care Spirometry Pathways for Diagnosis of Lung Disease (APRIL) (APRIL)

Lung Diseases

United Kingdom
Imperial College London
Swiss National Science Foundation; Royal Brompton & Harefield NHS Foundation...

Completed

Fluctuation of Airway Function in Children With Asthma

Asthma

United Kingdom
Queen Mary University of London
Novartis Pharmaceuticals; University College, London; Barts & The London NHS... and other collaborators

Completed

Protective Role of Oxcarbazepine in Multiple Sclerosis (PROXIMUS)

Multiple Sclerosis

United Kingdom
Prof Corinne Faivre-Finn
Royal Marsden NHS Foundation Trust; The Leeds Teaching Hospitals NHS Trust; Cambridge... and other collaborators

Completed

Isotoxic Intensity Modulated Radiotherapy (IMRT) in Stage III Non Small Cell Lung Cancer (NSCLC) - A Feasibility Study (Isotoxic-IMRT)

Non Small Cell Lung Cancer

United Kingdom
Royal Devon and Exeter NHS Foundation Trust
University of Oxford; NHS Tayside; Oxford University Hospitals NHS Trust; University... and other collaborators

Completed

RetroMASTER - Retrospective Cohort MRC ABPI STratification and Extreme Response Mechanism in Diabetes (RetroMASTER)

Diabetes

United Kingdom
Erasmus Medical Center
King's College Hospital NHS Trust; Royal Brompton & Harefield NHS Foundation... and other collaborators

Completed

The Effect of Pirfenidone on Cough in Patients With Idiopathic Pulmonary Fibrosis (Cough-IPF)

Idiopathic Pulmonary Fibrosis

France, Italy, Netherlands
Pier Lambiase
University Hospital Southampton NHS Foundation Trust; The Royal Bournemouth...

Completed

Randomized Trial of Two Ablation Catheters in Paroxysmal Atrial Fibrillation

Atrial Fibrillation

United Kingdom
GlaxoSmithKline
Quintiles, Inc.; Imperial College London; Royal Free Hospital NHS Foundation... and other collaborators

Completed

A Study to Evaluate the Safety of GSK2398852 When Co-administered With GSK2315698 in Patients With Systemic Amyloidosis

Amyloidosis

United Kingdom
University of Ulster
Bedford Hospital NHS Trust; Midlands Eye Clinic; Royal Victoria Hospital, Belfast

Completed

The Efficacy of Two Potential Diagnostic Assays for Herpes Simplex Keratitis (HSK)

Herpes Simplex Keratitis

United Kingdom
Royal Surrey County Hospital NHS Foundation Trust
University of Surrey; Target Ovarian Cancer

Unknown

EDMONd - Elemental Diet in Bowel Obstruction (EDMONd)

Peritoneal Diseases | Ovarian Neoplasms | Peritoneal Neoplasms | Ovarian Cancer | Abdominal Neoplasm | Bowel Obstruction | Primary Peritoneal Carcinoma | Metastatic Ovarian Cancer | Ovarian Disease

United Kingdom
King's College Hospital NHS Trust
University of Pennsylvania; Gilead Sciences; The Leeds Teaching Hospitals NHS... and other collaborators

Active, not recruiting

Genetic Determinants of Kidney Disease in People of African Ancestry With HIV (GEN-AFRICA)

Cardiovascular Diseases | Kidney Diseases | Obesity | Diabetes Mellitus | Genetic Predisposition to Disease | Kidney Injury | HIV Nephropathy

United Kingdom
Golden Jubilee National Hospital
NHS Lothian; Imperial College Healthcare NHS Trust

Unknown

Effects of Apelin on the Lung Circulation in Pulmonary Hypertension

Heart Failure | Pulmonary Arterial Hypertension

United Kingdom
University College, London
London School of Hygiene and Tropical Medicine; King's College London; Odense... and other collaborators

Completed

Effect of Remote Ischaemic Conditioning on Clinical Outcomes in STEMI Patients Undergoing PPCI (CONDI2/ERIC-PPCI)

Myocardial Reperfusion Injury | STEMI

Denmark, United Kingdom, Spain, Serbia
Royal Surrey County Hospital NHS Foundation Trust
European Society of Intensive Care Medicine

Not yet recruiting

POLECAT: Perioperative Delta Renin Concentration (POLECAT)

Acute Kidney Injury | Post Operative Vasoplegic Syndrome
Our Lady's Hospice and Care Services
Royal Surrey County Hospital NHS Foundation Trust

Recruiting

Palliative Care and Oncology Survey on Terminology (POST)

Cancer

Ireland, United Kingdom
Royal Free Hospital NHS Foundation Trust
Merck Sharp & Dohme LLC; University College, London

Completed

Immunophenotyping of Melanoma Patients on Treatment With Pembrolizumab (PASIP)

Melanoma | Neoplasms

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
University Hospital, Basel, Switzerland; Bioxydyn Ltd, Manchester

Unknown

MRI in Cystic Fibrosis and Primary Ciliary Dyskinesia

Cystic Fibrosis | Primary Ciliary Dyskinesia

United Kingdom
University Hospital Southampton NHS Foundation...
Royal Free and University College Medical School

Completed

Targeted Radiotherapy in HSCT for Poor Risk Haematological Malignancy

Lymphoma | Myeloma | Acute Leukaemia | Chronic Leukaemia

United Kingdom
NHS Greater Glasgow and Clyde
King's College London; University of Oxford; Royal Free Hospital NHS Foundation... and other collaborators

Completed

Precision Medicine With Zibotentan in Microvascular Angina (PRIZE)

Microvascular Angina

United Kingdom
National Heart and Lung Institute
Royal Brompton & Harefield NHS Foundation Trust; British Heart Foundation

Completed

Cardiac Rehabilitation for the Treatment of Refractory Angina

Coronary Disease | Angina Pectoris

United Kingdom
University of Leicester
Guy's and St Thomas' NHS Foundation Trust; Sheffield Teaching Hospitals NHS... and other collaborators

Recruiting

Study on Optimal Temperature During Cardiopulmonary Bypass (THERMIC-4) (THERMIC-4)

Cardiovascular Diseases | Ischemic Heart Disease | Valvular Heart Disease | Surgery-Complications

United Kingdom
University of Southampton
University of Leeds; Newcastle-upon-Tyne Hospitals NHS Trust; National Institute... and other collaborators

Not yet recruiting

Promoting Increased Physical Activity in Hospitalised Older Adults (PIVOT)

Hospital-associated Deconditioning
Belfast Health and Social Care Trust
Barts & The London NHS Trust; University Hospitals, Leicester; Bristol Royal... and other collaborators

Completed

Febrile Infants - Diagnostic Assessment and Outcome (FIDO)

Bacterial Infections | Urinary Tract Infections | Meningitis, Bacterial

United Kingdom, Ireland
British Cardiac Research Trust
Lund University; Royal Free Hospital NHS Foundation Trust; London North West... and other collaborators

Unknown

Progression of Coronary Atherosclerosis in Asymptomatic Diabetic Subjects (PROCEED)

Coronary Artery Disease | Type 2 Diabetes

United Kingdom
University of Ulster
Belfast Health and Social Care Trust; Sheffield Teaching Hospitals NHS Foundation... and other collaborators

Recruiting

Awareness Detection and Communication in Disorders of Consciousness

Stroke | Paralysis | Motor Neuron Disease | Disorder of Consciousness | Physical Disability

United Kingdom, Ireland
Cambridge University Hospitals NHS Foundation Trust
GlaxoSmithKline; University of Cambridge; Royal Brompton & Harefield NHS Foundation... and other collaborators

Completed

Losmapimod in Chronic Obstructive Pulmonary Disease Patients Stratified by Fibrinogen. (EVOLUTION)

Chronic Obstructive Pulmonary Disease

United Kingdom
Queen Margaret University
King's College Hospital NHS Trust; Sheffield Hallam University; University Hospital... and other collaborators

Recruiting

Development and Testing of the Kidney BEAM-KIDS Digital Platform for Children After Kidney Transplantation (BEAM-KIDs)

Kidney Transplantation

United Kingdom
University of Liverpool
Imperial College London; Royal Liverpool University Hospital; University of Surrey and other collaborators

Unknown

The Effect of Exercise Intervention on Insulin Resistance in Non-alcoholic Fatty Liver Disease (NAFLD)

Non Alcoholic Fatty Liver Disease

United Kingdom
University Hospital Birmingham
Royal Free Hospital NHS Foundation Trust; University of Edinburgh; University...

Unknown

Comparing the Effects of Spironolactone With Chlortalidone on LV Mass in Patients With CKD (SPIRO-CKD)

Renal Insufficiency, Chronic | Cardio-Renal Syndrome

United Kingdom
Liverpool John Moores University
Liverpool University Hospitals NHS Foundation Trust; Royal Liverpool University... and other collaborators

Active, not recruiting

Can Brisk Walking Combined With Ingestion of a Lipid-lowering Drug Improve Fat Metabolism in Muscle?

Pre Diabetes

United Kingdom
University College, London
Medical Research Council; Royal Free Hospital NHS Foundation Trust; ViiV Healthcare

Completed

Adding MAraViroc &/or METformin for Hepatic Steatosis in People Living With HIV (MAVMET)

Hepatic Steatosis | HIV-1-infection

United Kingdom
Liverpool John Moores University
Liverpool University Hospitals NHS Foundation Trust; Royal Liverpool University... and other collaborators

Completed

Can the Health Benefits of a Walking-based Exercise Programme be Enhanced by Co-ingestion of a Lipid-lowering Drug?

Pre-diabetes

United Kingdom
University Hospital Southampton NHS Foundation...
Imperial College Healthcare NHS Trust; Royal Devon and Exeter NHS Foundation... and other collaborators

Completed

WT1 Immunity Via DNA Fusion Gene Vaccination in Haematological Malignancies by Intramuscular Injection Followed by Intramuscular Electroporation (WIN)

Leukaemia (Acute) | Leukaemia (Chronic) | Leukaemia (Acute Myeloid) | Leukaemia (Acute Lymphoblastic) | Leukaemia (Acute Promyelocytic)

United Kingdom
Dr Michael Scott
Merck Sharp & Dohme LLC; Royal Surrey County Hospital NHS Foundation Trust

Unknown

RADOX' Reduced Abdominal Distension and Oxygen Delivery (RADOX)

Colorectal Cancer

United Kingdom
Sheffield Hallam University
AstraZeneca; Belfast Health and Social Care Trust; Sheffield Teaching Hospitals... and other collaborators

Recruiting

Optimising Secondary Prevention and Quality of Life in Early Cardiac Rehabilitation (OSPREY-CR)

Myocardial Infarction | Cardiovascular Diseases | Coronary Artery Disease | Heart Failure | Coronary Heart Disease | Acute Coronary Syndrome

United Kingdom
Bournemouth University
Royal Bournemouth and Christchurch Hospitals NHS Foundation Trust; Oomph! Wellness and other collaborators

Withdrawn

Effect of an Intervention on Health in Older Care Home Residents

Frail Elderly Syndrome | Frailty | Sedentary Behavior | Life Style Induced Illness | Lifestyle, Sedentary
University College, London
University of Nottingham; Imperial College London; Cambridge University Hospitals... and other collaborators

Unknown

The MRC/ABPI COPD Cohort v1.7 (COPDMAP)

COPD

United Kingdom
Nottingham University Hospitals NHS Trust
The Royal College of Surgeons of England; EIDO Healthcare

Completed

Multimedia Informed Consent & PROMs in Laparoscopic Cholecystectomy (EPICS)

Gallstone Disease

United Kingdom
King's College Hospital NHS Trust

Completed

Study of Episodic Breathlessness in Patients With Lung Cancer or Other Advanced Disease

Lung Cancer | Metastatic Cancer | Dyspnea

United Kingdom
Imperial College London
Medical Research Council; University of Oxford; Guy's and St Thomas' NHS Foundation... and other collaborators

Completed

Research In Viral Eradication of HIV Reservoirs (RIVER)

HIV

United Kingdom
Barts & The London NHS Trust
King's College London; Cambridge University Hospitals NHS Foundation Trust; Medical... and other collaborators

Completed

Stromal TARgeting for PAncreatic Cancer (STAR_PAC) (STAR_PAC)

Pancreatic Adenocarcinoma

United Kingdom

Clinical Trials Sponsored by Royal National Orthopaedic Hospital NHS Trust

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Austria

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations