Clinical Trials Sponsored by The Crown Institute

Total 5274 results

The Methodist Hospital Research Institute

Completed

L-NMMA Plus Taxane Chemotherapy in Refractory Locally Advanced or Metastatic Triple Negative Breast Cancer Patients

Metastatic Triple Negative Breast Cancer

United States
The Methodist Hospital Research Institute

Completed

68 Ga-PSMA for High Risk Prostate Cancer

Prostate Cancer | High Risk

United States
The Methodist Hospital Research Institute

Active, not recruiting

Phase Ib of L-NMMA and Pembrolizumab

Non-Small Cell Lung Cancer | DNA Repair-Deficiency Disorders | Head and Neck Squamous Cell Carcinoma | Urothelial Carcinoma Bladder | Classical Hodgkin Lymphoma | Malignant Melanoma

United States
The Methodist Hospital Research Institute

Completed

Low Dose IL2 Immunotherapy in AD

Alzheimer Disease

United States
The Methodist Hospital Research Institute

Completed

Intraosseous Vancomycin in Primary Total Hip Arthroplasty - Designing a Protocol

Joint Diseases | Prosthetic Joint Infection | Vancomycin

United States
The Netherlands Cancer Institute
AstraZeneca

Active, not recruiting

Monalizumab and Trastuzumab In Metastatic HER2-pOSitive breAst Cancer: MIMOSA-trial (MIMOSA)

Breast Cancer

Netherlands
The Methodist Hospital Research Institute

Completed

Deep Brain Stimulation in Patients With LUTS

Neurogenic Bladder | Bladder Dysfunction

United States
The Methodist Hospital Research Institute

Unknown

Single Dose rATG for Renal Allograft Rejection

Acute (Cellular) Renal Allograft Rejection

United States
The Methodist Hospital Research Institute

Completed

Motion Capture: Baseball Swing

Elbow Force

United States
The Methodist Hospital Research Institute

Unknown

Clazakizumab vs. Placebo - COVID-19 Infection

COVID-19 Infection

United States
The Netherlands Cancer Institute
AstraZeneca

Unknown

Assess the Safety of Immunotherapy Induction With Tremelimumab and Durvalumab Prior to Chemoradiotherapy and/or Resection in the Treatment (Induction)

Stage III NSCLC

Netherlands
The Methodist Hospital Research Institute

Unknown

Intraperitoneal and Extraperitoneal Uterosacral Ligament Suspensions for Post-Hysterectomy Vaginal Vault Prolapse

Vaginal Vault Prolapse | Post-Hysterectomy Vaginal Vault Prolapse | Prolapse, Vaginal

United States
The Methodist Hospital Research Institute

Completed

Ciprofloxacin for Prevention of BK Infection

BK Virus Infection

United States
The Methodist Hospital Research Institute

Unknown

Multi-scale Modeling of Breast Conserving Therapy (BCT)

Breast Cancer

United States
The Netherlands Cancer Institute
GlaxoSmithKline

Unknown

Lapatinib Plus Trametinib in KRAS Mutant NSCLC (M14LTK)

Colorectal Cancer

Netherlands
The Methodist Hospital Research Institute

Withdrawn

Phase II Trial of Chemotherapy With Temodar With Topotecan for CNS Metastasis of Solid Tumors

Brain Metastases | Central Nervous System (CNS) Metastases

United States
The Netherlands Cancer Institute
GlaxoSmithKline

Completed

Combined Modality Treatment of Sarcomas of the Extremities (PASART-1)

Sarcoma,Soft Tissue

Netherlands
The Methodist Hospital Research Institute

Terminated

Adrenal Insufficiency in Septic Shock

Septic Shock | Acute Adrenal Insufficiency

United States
Rockefeller University
The Rogosin Institute

Terminated

The Effect of Nighttime Dialysis on the Inflammation of Kidney Failure

End-Stage Renal Disease

United States
The George Institute
Peking University

Completed

China Plant Sterol Trial

Cardiovascular Diseases | Hypercholesterolemia

China
The Bionics Institute of Australia

Not yet recruiting

EarGenie MVP Performance Evaluation

Hearing Impaired Children

Australia
The Bionics Institute of Australia

Recruiting

The Development of a System for the Measurement of Tremor

Tremor

Australia
The Methodist Hospital Research Institute

Recruiting

Effect of BFR Rehab After Achilles Tendon Rupture

Achilles Tendon Rupture

United States
The Methodist Hospital Research Institute

Recruiting

rTMS in Overactive Bladder (TMS_OAB)

Overactive Bladder | Urinary Incontinence | Urge Incontinence | Urinary Incontinence, Urge | Overactive Bladder Syndrome | Urgency-frequency Syndrome

United States
The Methodist Hospital Research Institute

Recruiting

Neuromodulating Cortical Regions Involved in Neurogenic Bladder in MS (MSBLADDER)

Multiple Sclerosis | Overactive Bladder | Neurogenic Bladder

United States
The Methodist Hospital Research Institute

Recruiting

IO vs IV Vancomycin in Tourniquetless TKA

Infection, Surgical Site

United States
The Netherlands Cancer Institute
AstraZeneca

Recruiting

Osimertinib Resistance in Patients With Non-small-cell Lung Carcinoma That Have Progressed. (OSIRIS)

Non-small-cell Lung Carcinoma

Netherlands
The Methodist Hospital Research Institute

Recruiting

Limb Occlusion Pressure Tourniquets to Decrease Pain After Surgery (LOP)

Limb Occlusion Pressure

United States
The Methodist Hospital Research Institute

Recruiting

HSV-tk and XRT and Chemotherapy for Newly Diagnosed GBM

Glioblastoma | Anaplastic Astrocytoma

United States
The Methodist Hospital Research Institute

Completed

Sleep & Stress in Healthcare Providers After Defined Music Intervention Measure by 7-Tesla fMRI & Actigraphy

Burnout, Professional | Stress, Psychological | Sleep Deprivation | Music Therapy

United States
The Methodist Hospital Research Institute

Completed

Neuromuscular Training in Female Youth Soccer (NMT)

Injury;Sports

United States
The Netherlands Cancer Institute
4SC

Active, not recruiting

Multicenter Phase 1b Trial Testing the Neoadjuvant Combination of Domatinostat, Nivolumab and Ipilimumab in IFN-gamma Signature-low and IFN-gamma Signature-high RECIST 1.1-measurable Stage III Cutaneous or Unknown Primary Melanoma (DONIMI)

Malignant Melanoma Stage III

Netherlands
The Netherlands Cancer Institute
AstraZeneca

Active, not recruiting

Olaparib and Radiotherapy in Head and Neck Cancer

Head and Neck Neoplasms | Carcinoma, Squamous Cell | Laryngeal Cancer Stage II | Laryngeal Cancer Stage III

Netherlands
The Methodist Hospital Research Institute

Completed

Olive Oil for High Risk Breast Cancer Prevention in Women

Breast Cancer

United States
The Netherlands Cancer Institute
Amgen

Active, not recruiting

Neo-adjuvant T-VEC + Nivolumab Combination Therapy for Resectable Early Metastatic (Stage IIIB/C/D-IV M1a) Melanoma With Injectable Disease (NIVEC)

Melanoma Stage IV | Melanoma Stage III

Netherlands
The Netherlands Cancer Institute
Bayer

Completed

Treatment Outcomes in a Non-study Population of Symptomatic mCRPC Patients Treated With Radium-223 (ROTOR)

Bone Metastases | Prostate Cancer Metastatic

Netherlands
The Methodist Hospital Research Institute

Enrolling by invitation

Cryoablation of Intercostal Nerves for Post-Operative Pain Management in Opioid-Tolerant Patients

Pain | Pain, Postoperative

United States
The Methodist Hospital Research Institute

Active, not recruiting

Mapping of the Human Brainstem During Continence and Micturition: Noninvasive 7-T fMRI Study

Healthy

United States
The Methodist Hospital Research Institute

Completed

Chloroquine With Taxane Chemotherapy for Advanced or Metastatic Breast Cancer After Anthracycline Failure (CAT) (CAT)

Breast Cancer | Breast Neoplasms

United States
The Methodist Hospital Research Institute

Completed

Educating Women About Pelvic Floor Disorders During Pregnancy

Pelvic Organ Prolapse | Stress Urinary Incontinence | Pelvic Floor Disorders

United States
The Netherlands Cancer Institute
UNICANCER

Active, not recruiting

Radiation Dose Intensity Study in Breast Cancer in Young Women

Breast Cancer

France, Netherlands
The Methodist Hospital Research Institute

Completed

Intraosseous Morphine in Primary TKA

Pain, Acute | Arthritis Knee | Knee Disease

United States
The Methodist Hospital Research Institute

Unknown

Convalescent Plasma for the Treatment of COVID-19 (Coronavirus Disease 2019)

Covid19

United States
The Methodist Hospital Research Institute

Completed

Blood Flow Restriction Training for The Shoulder

Healthy

United States
The Methodist Hospital Research Institute

Unknown

Clinical Effectiveness of Pre-operative Methadone in Single Level Lateral Transpsoas Interbody Fusions

Degenerative Disc Disease | Spondylolisthesis, Lumbar Region
The Methodist Hospital Research Institute

Terminated

The Use of CoSeal (Sealant Agent) in Patients During Left Ventricular Assist Device Surgery

Heart Failure | Ventricular Dysfunction

United States
The Methodist Hospital Research Institute

Completed

A Trial of Esophageal and Gastric Stenting for Leak or Perforation (ESO-stent)

Esophageal or Gastric Perforations | Esophageal or Gastric Leaks

United States
The Institute for Family Health

Unknown

IFH Depression Registry 2013

Depression

United States
The Methodist Hospital Research Institute

Completed

Hyperlipidemia and Statin Therapy in Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis

United States
The George Institute
The University of New South Wales

Recruiting

Trial of Enhanced Neurostimulation for Anorexia (TRENA)

Anorexia Nervosa

Australia

Clinical Trials Sponsored by The Crown Institute

Sponsors and Collaborators

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Drug Interventions

CROs by country

CROs in Congo, DR of

Conditions

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