Clinical Trials Sponsored by TwinStrand Biosciences

Total 1866 results

Calithera Biosciences, Inc

Terminated

Study of Mivavotinib (CB-659) in Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)

Non-GCB/ABC Diffuse Large B-Cell Lymphoma | With and Without MyD88 and/or CD79B Mutations

United States
Pardes Biosciences, Inc.

Active, not recruiting

PBI-0451 (Pomotrelvir) Phase 2 Study in Nonhospitalized Symptomatic Adults With COVID-19

COVID-19

United States
Cortice Biosciences, Inc.

Suspended

Dose-Escalation Study of TPI 287 + Avastin Followed by Randomized Study of the Same Versus Avastin for Glioblastoma

Glioblastoma Multiforme

United States
Evopoint Biosciences Inc.

Completed

Pharmacokinetics of XNW4107 in Subjects With Various Degrees of Renal Function

Bacterial Infections

United States
Evopoint Biosciences Inc.

Completed

Study to Evaluate Safety, Tolerability, and Pharmacokinetics of XNW4107 Alone or in Combination With Imipenem/Cilastatin

Bacterial Infections

United States
Chipscreen Biosciences, Ltd.

Active, not recruiting

Trial of Chidamide in Combination With Envafolimab in Patients With PD-1 Inhibitor Resistant Advanced NSCLC.

Non Small Cell Lung Cancer

China
Calithera Biosciences, Inc

Completed

Safety and Efficacy Study of Sapanisertib in Combination With Exemestane or Fulvestrant in Postmenopausal Women With Estrogen Receptor Positive/Human Epidermal Growth Factor Receptor 2 Negative (ER+/HER2-) Metastatic Breast Cancer

Breast Cancer

United States, Belgium, France
Calithera Biosciences, Inc

Withdrawn

A Study to Assess Mass Balance, Pharmacokinetics (PK), and Metabolism of Orally Administered [14 C]-TAK-659 in Participants With Advanced Solid Tumor and/or Lymphoma Malignancies

Advanced Solid Neoplasms | Lymphoma Neoplasms
Precision BioSciences, Inc.

Completed

Dose-escalation Study of Safety of PBCAR20A in Subjects With r/r NHL or r/r CLL/SLL

Lymphoma, Non-Hodgkin | Chronic Lymphocytic Leukemia | B-cell Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma | B-cell Non Hodgkin Lymphoma | Leukemia, Lymphocytic, Chronic | Non-Hodgkin's Lymphoma, Relapsed | Non-Hodgkin's Lymphoma Refractory | Chronic Lymphoid Leukemia in Relapse

United States
Calithera Biosciences, Inc

Completed

Effect of Sapanisertib (MLN0128) on the QTc Interval in Participants With Advanced Solid Tumors

Advanced Solid Tumors

United States
Pulse Biosciences, Inc.

Completed

CellFX Treat & Resect Low-Risk BCC Feasibility Study

BCC | BCC - Basal Cell Carcinoma | Excision Margin

United States
Evelo Biosciences, Inc.

Terminated

Safety and Efficacy of EDP1815 in the Treatment of Patients Hospitalized With COVID-19 Infection

Covid19

United States, Turkey
IGM Biosciences, Inc.

Terminated

Evaluation of IGM-6268 in Healthy Volunteers

Healthy Volunteers

United States
Aptose Biosciences Inc.

Terminated

A Study of APTO-253 in Patients With Relapsed or Refractory AML or MDS

Acute Myelogenous Leukemia | Acute Myelogenous Leukemia in Relapse | Acute Myelogenous Leukemia, Relapsed, Adult | Acute Myelogenous Leukemia, Adult | High Risk Myelodysplasia

United States
Liminal BioSciences Ltd.

Terminated

A Healthy Volunteer Study to Compare Fezagepras (PBI-4050) With Sodium Phenylbutyrate

Hyperammonemia

United Kingdom
Presage Biosciences
Takeda

Completed

Intratumoral Microdosing of TAK-981 in Head and Neck Cancer

Head and Neck Cancer

United States
Cellectar Biosciences, Inc.

Completed

A Trial of NOV-205 in Hepatitis C Patients Who Failed Standard Therapy (NOV-205)

Hepatitis C

United States
Genocea Biosciences, Inc.

Terminated

TiTAN-1: Safety, Proliferation and Persistence of GEN-011 Autologous Cell Therapy

Melanoma | Renal Cell Carcinoma | Squamous Cell Carcinoma of Head and Neck | Non-small Cell Lung Cancer | Small-cell Lung Cancer | Urothelial Carcinoma | Anal Squamous Cell Carcinoma | Merkel Cell Carcinoma | Cutaneous Squamous Cell Carcinoma

United States
Keymed Biosciences Co.Ltd

Completed

Subcutaneously CM310/Placebo in Patients With Chronic Rhinosinusitis With Nasal Polyposis (CROWNS-1)

Chronic Rhinosinusitis (Diagnosis) | Nasal Polyps

China
Calithera Biosciences, Inc

Terminated

Study of CB-839 (Telaglenastat) in Combination With Talazoparib in Patients With Solid Tumors

Clear Cell Renal Cell Carcinoma | Colorectal Cancer | Solid Tumor | CRC | TNBC - Triple-Negative Breast Cancer | ccRCC | RCC

United States
Chipscreen Biosciences, Ltd.

Completed

Trial of Chidamide in Combination With Exemestane in Patients With Advanced Breast Cancer

Breast Cancer

China
Sagimet Biosciences Inc.

Completed

Study of TVB 2640 in Subjects With Non-Alcoholic Steatohepatitis (NASH)

Non-Alcoholic Fatty Liver Disease

China, United States
Senhwa Biosciences, Inc.

Completed

Study of CX-4945 in Combination With Gemcitabine and Cisplatin for Frontline Treatment of Cholangiocarcinoma

Cholangiocarcinoma

Korea, Republic of, United States, Taiwan
Castle Biosciences Incorporated

Terminated

Five Year Study to Track Use of DecisionDX-Melanoma Test in Patients With Cutaneous Melanoma and Associated Patient Outcomes (EXPAND)

Cutaneous Melanoma

United States
Knopp Biosciences
Biogen

Completed

Dexpramipexole Japanese PK Study

Amyotrophic Lateral Sclerosis

United Kingdom
Neurocrine Biosciences
Takeda

Completed

Study to Determine D-amino Acid Oxidase Brain Enzyme Occupancy of TAK-831 After Single-dose Oral Administration

Healthy

United Kingdom
Neurocrine Biosciences
Takeda

Completed

Efficacy, Tolerability, and Pharmacokinetics of Multiple Doses of Oral TAK-831 in Adults With Friedreich Ataxia

Friedreich Ataxia

United States
Neurocrine Biosciences
Takeda

Terminated

A TAK-831-1001, Single and Multiple Rising Dose Study in Healthy Participants

Schizophrenia, Cerebellar Ataxia

United Kingdom
Neurocrine Biosciences
Takeda

Completed

Phase 1 Study of TAK-831 in Healthy Adult Asian Subjects

Healthy Volunteers

Japan
Ark Biosciences Inc.

Completed

A Study of AK0529 to Evaluate Pharmacokinetics and Safety in Chinese Healthy Volunteers

Healthy

China
Keymed Biosciences Co.Ltd

Completed

Dose Escalation Trial of CM310 in Patients With Moderate-to-Severe Atopic Dermatitis (AD)

Moderate-to-severe Atopic Dermatitis

China
Neurocrine Biosciences
Takeda

Completed

A Study to Evaluate Central Nervous System (CNS) Pharmacodynamic Activity of TAK-653 in Healthy Participants Using Transcranial Magnetic Stimulation (TMS)

Healthy Volunteers

Netherlands
Chipscreen Biosciences, Ltd.

Completed

Chiauranib in Combination With Chemotherapy in Patients With Ovarian Cancer

Ovarian Cancer

China
Neurocrine Biosciences
Takeda

Completed

A Single-Dose Positron Emission Tomography (PET) Study to Determine the Effect of TAK-041 on Amphetamine-Induced Dopamine Release in the Central Nervous System (CNS)

Healthy Volunteers

United Kingdom
Nanospectra Biosciences, Inc.

Completed

MRI/US Fusion Imaging and Biopsy in Combination With Nanoparticle Directed Focal Therapy for Ablation of Prostate Tissue

Neoplasms of the Prostate

United States
Liminal BioSciences Ltd.

Terminated

Study to Evaluate Safety, Efficacy of PBI-4050 & Its Effect on Relevant Biomarkers in T2DM Patients With Metabolic Syndrome

Type 2 Diabetes Mellitus | Metabolic Syndrome

Canada
Piper Biosciences, Inc.

Unknown

Impact of a Chewable Plant Sterol Supplement on LDL-C in A Real-World Setting

Hyperlipidemia

United States
CeloNova BioSciences, Inc.

Unknown

Randomized Trial of COBRA PzF Stenting to Reduce Duration of Triple Therapy (COBRA-REDUCE)

Angina, Stable | Angina, Unstable | Anticoagulants

United States, Denmark, France, Germany, Belgium, Italy, Latvia, Switzerland
Coherus Biosciences, Inc.

Completed

Comparison of CHS-1420 Versus Humira in Subjects With Chronic Plaque Psoriasis (PsOsim)

Plaque Psoriasis

United States, Canada, Bulgaria, Chile, Croatia, Estonia, Georgia, Israel, Italy, Latvia, Moldova, Republic of, Poland, Russian Federation, Slovakia, South Africa, Ukraine
Cogent Biosciences, Inc.

Terminated

Study of ACTR T Cell Product in Combination With Trastuzumab in Subjects With HER2-Positive Advanced Solid Tumor Cancers

Solid Tumor | HER-2 Protein Overexpression

United States
LegoChem Biosciences, Inc

Completed

A Phase II Clinical Study of LCB01-0371 to Evaluate the EBA, Safety and PK

Pulmonary Tuberculosis

Korea, Republic of
Chipscreen Biosciences, Ltd.

Completed

Study of Chiglitazar Compare With Placebo in Type 2 Diabetes Patients (CMAP)

Type 2 Diabetes

China
Proclara Biosciences, Inc.

Terminated

Multiple Ascending Dose Study in Healthy Subjects

Amyloidosis

Netherlands
Chipscreen Biosciences, Ltd.

Completed

Clinical Trial of Chidamide Combined With CHOP in Peripheral T-cell Lymphoma Patients

Peripheral T-cell Lymphoma

China
Nielsen BioSciences, Inc.

Completed

Safety and Efficacy of Varying Regimens of CANDIN for Treatment of Common Warts (Verruca Vulgaris)

Warts

United States
Liminal BioSciences Ltd.

Completed

A Phase 2 Study to Evaluate the Safety and Tolerability of PBI-4050 in Patients With Idiopathic Pulmonary Fibrosis (IPF)

Idiopathic Pulmonary Fibrosis (IPF)

Canada
Prothena Biosciences Ltd.

Terminated

Study in Subjects With Light Chain (AL) Amyloidosis

AL Amyloidosis

United States, Spain, Australia, Italy, Germany, Austria, Greece, France, Israel, United Kingdom
Ardea Biosciences, Inc.

Completed

Lesinurad/Allopurinol 200/300 Fixed-Dose Combination (FDC) Tablets Bioequivalence.

Gout

Brazil
Genocea Biosciences, Inc.

Completed

Safety and Immunogenicity Study of Therapeutic HSV-2 Vaccine

Genital Herpes Simplex Type 2

United States
Ardea Biosciences, Inc.

Completed

RDEA3170 and Allopurinol Combination Study in Gout Subjects

Gout

United States

Clinical Trials Sponsored by TwinStrand Biosciences

Sponsors and Collaborators

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CROs in Israel

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