Search clinical trials for: CD122-Biased Agonist

Total 14371 results

Imperial College London

Recruiting

PsilOCD: A Pharmacological-Challenge Feasibility Study

Obsessive-Compulsive Disorder

United Kingdom
The Affiliated Hospital of Xuzhou Medical University

Recruiting

Association of Gene Polymorphism With Susceptibility to T2DM and the Therapeutic Responses to Exenatide in Chinese Patients With T2DM

Type 2 Diabetes Mellitus | Susceptibility, Genetic

China
Hongmeng Yu

Recruiting

Efficacy and Safety of Induction Chemotherapy for Olfactory Neuroblastoma (ESICON) (ESICON)

Olfactory Neuroblastoma

China
Shanxi Bethune Hospital

Recruiting

Clinical Study of Reduced-dose Pomalidomide and Cyclophosphamide Combined With Dexamethasone in the Treatment of Patients With Debilitating RRMM

Multiple Myeloma in Relapse

China
United States Naval Medical Center, Portsmouth

Not yet recruiting

Liposomal Bupivacaine vs Bupivacaine With Dexmedetomidine in Erector Spinae Plane Blocks for Mastectomies

Breast Cancer
Maastricht University Medical Center

Recruiting

Real-world Evaluation of Diagnostic and Treatment Strategies in Low-Risk Basal Cell Carcinoma (REDT-BCC)

Basal Cell Carcinoma

Netherlands
Christopher D. Verrico

Recruiting

Exenatide For Reducing the Reinforcing Effects of Cocaine

Cocaine Use Disorder

United States
Nantes University Hospital

Not yet recruiting

Study Testing Two Conditioning Regimen With a Single Prophylaxis of GVHD by Cyclophosphamide and Methotrexate Post-transplant in Patients Eligible for Matched-donor Allograft Transplantation (CY-MET-RIC)

Hematologic Malignancy | Graft Versus Host Disease
National Cancer Institute (NCI)

Recruiting

Autologous T-cells Genetically Engineered to Express Receptors Reactive Against KRAS Mutations in Conjunction With a Vaccine Directed Against These Antigens in Participants With Metastatic Cancer

Breast Cancer | Colorectal Cancer | Ovarian Cancer | Non-Small Cell Lung Cancer | Gastrointestinal Cancer | Genitourinary Cancer | Metastatic Solid Cancers

United States
National Institute of Respiratory Diseases, Mexico

Recruiting

Effectiveness of Combined Tobacco Treatment in Hospitalized Subjects

Tobacco Smoking | Nicotine Addiction | Nicotine Withdrawal | Nicotine Replacement Therapy | Tobacco Withdrawal

Mexico
Kite, A Gilead Company

Recruiting

Study of KTE-X19 in Adult Japanese Participants With Relapsed/Refractory Mantle Cell Lymphoma or Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia (JKART-1)

Relapsed/Refractory Mantle Cell Lymphoma | Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia

Japan
Insel Gruppe AG, University Hospital Bern
Psychiatric University Hospital, Zurich

Recruiting

Molecular Imaging Study of Harmine/DMT: a Basic Research Approach (HaD-PET)

Neuropharmacological Investigation of Ayahuasca Constituents DMT and Harmine

Switzerland
St. Joseph's Healthcare Hamilton

Not yet recruiting

Early Sedation With Dexmedetomidine vs. Placebo in Older Ventilated Critically Ill Patients (SPICEIV)

Respiratory Insufficiency
Jimma University

Recruiting

Bromocriptine in Dilated Cardiomyopathy Among Women of Reproductive Age

Dilated Cardiomyopathy

Ethiopia
Guangzhou Lupeng Pharmaceutical Company LTD.

Recruiting

Phase Ib Study of Rocbrutinib in Combination With R-CHOP in Patients With Newly Diagnosed B-cell Non-Hodgkin Lymphoma

B-cell Non-Hodgkin Lymphoma

China
Jagiellonian University
University Hospital in Krakow

Not yet recruiting

Beta-blockade in Unruptured Intracranial Aneurysm (BBLURAN)

Intracranial Aneurysm

Poland
Bio-innova Co., Ltd

Not yet recruiting

Nebivolol Tablets 5 mg Relative to Nebilet Tablets 5 mg

Healthy Subjects
Hassan II University

Not yet recruiting

Continuous Infusion of Norepinephrine vs Phenylephrine During Spinal Anesthesia for Cesarean Section (INPEACE) (INPEACE)

Cesarean Section Complications | Hypotension

Morocco
Ruijin Hospital

Recruiting

Evaluate the Efficacy and Safety of Allogeneic Haematopoietic Stem Cell Transplantation With FBM Conditioning for MDS

Myelodysplastic Syndromes | Myelodysplastic Syndrome With Excess Blasts-2 | Myelodysplastic Syndrome With Excess Blasts-1

China
OHSU Knight Cancer Institute
Genentech, Inc.; Oregon Health and Science University

Not yet recruiting

Mosunetuzumab With Chemotherapy for the Treatment of Patients With Untreated C-Myc Rearrangement Positive High Grade B Cell Lymphoma or Diffuse Large B Cell Lymphoma

Diffuse Large B-Cell Lymphoma | High Grade B-Cell Lymphoma

United States
Ohio State University Comprehensive Cancer Center
National Institute on Drug Abuse (NIDA)

Not yet recruiting

Effects of Tobacco Cut and Nicotine Form on the Abuse Liability of Moist Snuff

Tobacco-Related Carcinoma

United States
Uppsala University
Dalarna County Council, Sweden; Uppsala County Council, Sweden

Not yet recruiting

Bortezomib-bendamustine-melphalan vs Melphalan for Multiple Myeloma

Myeloma Multiple
Beijing Friendship Hospital

Recruiting

the Effects of Different Treatment Schemes on Cognitive Function of Patients With Idiopathic Membranous Nephropathy

Mild Cognitive Impairment | Idiopathic Membranous Nephropathy

China
Anavex Life Sciences Corp.
Cognitive Research Corporation; COGNISION; Hassman Research Institute

Recruiting

A Study of ANAVEX3-71 in Adults With Schizophrenia (SZ-001)

Schizophrenia

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...

Recruiting

PET Dynamics to Response-Adapted Neoadjuvant Therapy in TNBC (NeoADAPT)

Triple Negative Breast Cancer

United States
German Heart Institute
GE Healthcare

Not yet recruiting

Use of Stress-CMR Using Regadenoson and GE-267 in Adult Patients With Known or Suspected Coronary Artery Disease

Coronary Artery Disease

Germany
AstraZeneca

Recruiting

A Study to Investigate the Effects of PT027 (Budesonide/Albuterol Sulfate) Metered-dose Inhaler Compared With Placebo on Exercise-Induced Bronchoconstriction in Adult Patients With Asthma (BREATH)

Asthma, Exercise-Induced

Russian Federation
Aalborg University

Not yet recruiting

Effect of Ketamine, Amitriptyline and Their Combination on Histaminergic and Non-histaminergic Itch

Itch

Denmark
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Evaluation of Low-dose Albumin and Midodrine Versus Midodrine Alone in Outcome of Recurrent Ascites in Patients With Decompensated Cirrhosis.

Decompensated Cirrhosis

India
Beijing Union Pharmaceutical Factory Ltd
R&G Pharma Studies Co.,Ltd.

Recruiting

Phase Ⅲ Clinical Trial of Buagafuran Capsules in the Treatment of GAD (BGFN-2022-01)

Generalized Anxiety Disorder

China
Shanxi Bethune Hospital

Not yet recruiting

JY231(Internal Clinical Drug Code) Injection for the Treatment of Refractory Autoimmune Diseases (JY231、ADs)

Autoimmune Diseases

China
The First Affiliated Hospital with Nanjing Medical...

Recruiting

Chinese Medicine Treatment of Adolescent Sleep Disorders and Sleeping Pills Withdrawal

Sleep Disorder | Traditional Chinese Medicine

China
Fate Therapeutics

Recruiting

FT825/ONO-8250, an Off-the-Shelf, HER2 CAR-T, With or Without Monoclonal Antibodies in Advanced Solid Tumors

Advanced Solid Tumor

United States
Sawanpracharak hospital

Not yet recruiting

Dexmedetomidine vs Control on Attenuation Hemodynamic Response to Noxious Stimuli in CABG Surgical Patients (CABG)

CABG

Thailand
Beijing 302 Hospital

Not yet recruiting

Combination of ATG-based Conditioning Regimen and PTCy for GVHD Prevention in Allo-HSCT After PD-1 Blockade

Hematological Malignancies | Graft-versus-host Disease
Mỹ Đức Hospital

Recruiting

Artificial Cycle With or Without GnRH Agonist Pre-treatment for Frozen Embryo Transfer in Adenomyosis Patients (FET-ADE)

Adenomyosis | Frozen Embryo Transfer | IVF

Vietnam
M.D. Anderson Cancer Center
KSQ Therapeutics, Inc.

Recruiting

A Phase 1/2 Study of KSQ-001EX, Autologous Tumor Infiltrating Lymphocytes Engineered to Inactivate the SOCS1 Gene, in Patients With Select Advanced Solid Tumors

Melanoma | Head and Neck Neoplasms | Lung Neoplasms | Advanced Solid Tumor

United States
Fred Hutchinson Cancer Center
PromiCell Therapeutics, Inc.

Not yet recruiting

Cell Therapy (STEAP1 CART) With Enzalutamide for the Treatment of Patients With Metastatic Castration-Resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma | Stage IVB Prostate Cancer AJCC v8 | Metastatic Prostate Adenocarcinoma

United States
H. Lee Moffitt Cancer Center and Research Institute
Turnstone Biologics, Corp.

Recruiting

TBio-4101 and Pembro wi/ or w/o Chemo in Recurrent/Metastatic HNSCC

Squamous Cell Carcinoma of Head and Neck | Metastatic Squamous Cell Carcinoma

United States
University of Wisconsin, Madison

Not yet recruiting

High Confusion: Cannabis & Driving

Impairment, Cognitive | Impairment of Attention | Impairment, Psychomotor
All India Institute of Medical Sciences, Bhubaneswar

Recruiting

Atypical Antipsychotic-induced Mitochondrial Dysfunction in Patients With Schizophrenia

Schizophrenia

India
The University of Hong Kong

Recruiting

Liposomal Bupivacaine With Standard Bupivacaine Versus Dexmedetomidine With Standard Bupivacaine

Acute Pain

Hong Kong
Hvidovre University Hospital

Recruiting

Semaglutide and Physical Activity for Obesity and Multimorbidity

Obesity | Multimorbidity | Obesity Morbid

Denmark
Eurofarma Laboratorios S.A.

Not yet recruiting

Study of Fluticasone/Formoterol/Glycopyrronium for the Treatment Chronic Obstructive Pulmonary Disease (TRIPLAR) (TRIPLAR)

Chronic Obstructive Pulmonary Disease

Brazil
Poznan University of Medical Sciences

Recruiting

Dexamethasone vs. Dexmedetomidine for Popliteal Nerve Block in Pain Management After Pediatric Ankle and Foot Surgery

Foot Injuries and Disorders | Ankle Injuries and Disorders

Poland
Poznan University of Medical Sciences

Recruiting

Dexamethasone vs. Dexmedetomidine for ESPB in Pain Management After Hip Arthroplasty

Hip Pain Chronic | Hip Osteoarthritis | Hip Arthropathy

Poland
Poznan University of Medical Sciences

Recruiting

Dexamethasone vs. Dexmedetomidine for ESPB in Pain Management After Spine Surgery

Spinal Stenosis | Erector Spinae Plane Block | Spinal Fusion | Spine Disease

Poland
Mikhail N Koffarnus
National Institute on Drug Abuse (NIDA)

Not yet recruiting

Modeling Tobacco Regulatory Impacts in Appalachia Using the Experimental Tobacco Marketplace

Tobacco Use | Cigarette Use
King's College Hospital NHS Trust
European Society of Intensive Care Medicine; Royal Centre for Defence Medicine

Not yet recruiting

The Effect of Vasopressor Therapy on Renal Perfusion in Septic Shock (REPERFUSE)

Septic Shock | Acute Kidney Injury

United Kingdom
Assiut University

Recruiting

Could Ephedrine Replace Dexmedetomidine Fordexmedetomidine Prevention of Shivering in Women Undergoing Cesarean Section Under Spinal Anaesthesia

Prevention of Shivering With Spinal Anaesthesia

Egypt

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