Search clinical trials for: CD4 Count

Total 9361 results

American Gene Technologies International Inc.

Enrolling by invitation

An Antiretroviral Treatment Interruption (ATI) Study to Evaluate the Impact of Genetically Modified Autologous Cells (AGT103-T) to Suppress Human Immunodeficiency Virus Replication in the Absence of Antiretroviral Therapy

HIV

United States
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; Immuno-US

Completed

A Phase I/II Double-Blind Controlled Trial to Determine the Safety and Immunogenicity of HIV-1 MN rgp160 Immuno AG Vaccine Therapy in HIV-Infected Individuals With Greater Than or Equal to 500/mm3 CD4+ T Cells and 200-400/mm3 CD4+ T Cells

HIV Infections

United States
Huda Salman
The Leukemia and Lymphoma Society; iCell Gene Therapeutics

Recruiting

Chimeric Antigen Receptor T Cell Therapy Redirected to CD4 (CD4CAR)as a Second Line Treatment for Chronic Myelomonocytic Leukemia, CMML.

Chronic Myelomonocytic Leukemia

United States
National Center for Research Resources (NCRR)
Stanford University

Completed

A Maintenance Extension of Phase I Pilot Study of Chimeric Anti-CD4 Antibody M-T412 in Patients With Multiple Sclerosis

Multiple Sclerosis
National Institute of Allergy and Infectious Diseases...
Boehringer Ingelheim

Completed

An Open-Label, Pilot Study to Evaluate the Development of Resistance to Nevirapine (BI-RG-587) in HIV-Infected Patients With CD4 Cell Count >= 500/mm3

HIV Infections

United States
University of Pennsylvania
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

A Phase I Study of T-Cells Genetically Modified at the CCR5 Gene by Zinc Finger Nucleases SB-728mR in HIV-Infected Patients

Human Immunodeficiency Virus (HIV)

United States
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; Glaxo Wellcome

Completed

A Randomized, Double-Blind Phase II/III Trial of Monotherapy vs. Combination Therapy With Nucleoside Analogs in HIV-Infected Persons With CD4 Cells of 200-500/mm3

HIV Infections

United States, Puerto Rico, Tanzania
Medical University of Graz

Completed

HHV-6-specific T-cell Reconstitution Among Children and Adolescents After Allogeneic Stem. (CIRAST HHV-6)

Allogeneic Stem Cell Transplantation
University of Modena and Reggio Emilia

Completed

A Prospective, Open-label Trial of Two ABC/3TC Based Regimens in Late Presenter naïve Patients (CD4 <200 Cells/µL)

HIV Infection

Italy
Therapeutic Concepts

Completed

Nucleoside Switch Pilot for Virologically Controlled HIV Subjects With Decreasing CD4 Cells Who Have Received TDF-based ARV Therapy (EPZSwitch)

HiV1- Positive

United States
Chiron Corporation

Unknown

Safety and Effectiveness of L2-7001 (Interleukin-2) in HIV-Positive Patients Receiving Anti-HIV Therapy

HIV Infections

United States
University College Dublin
St Vincent's University Hospital, Ireland; University of Dublin, Trinity College

Completed

Dose-related Effects of Vitamin D3 on Immune Responses in Patients With Clinically Isolated Syndrome (CISAVID)

Multiple Sclerosis | Clinically Isolated Syndrome

Ireland
National Institute of Allergy and Infectious Diseases...

Completed

A Multicenter, Double Blind, Comparative Study of Zidovudine Alone Versus Zidovudine and Acyclovir as Treatment for HIV-Infected Patients With CD4+ Counts Less Than 200 Cells/mm3

HIV Infections

United States
Ventrus Biosciences, Inc

Completed

Efficacy and Safety Study With Diltiazem Hydrochloride Cream to Treat Anal Fissures

Chronic Anal Fissures

United States
The HIV Netherlands Australia Thailand Research...
National Health Security Office, Thailand; Ministry of Education, Thailand

Completed

Third Line Highly Active Antiretroviral Therapy (HAART) in HIV-infected Children

This Study is Designed to Collect Treatment Data of Thai Children on Third Line ARV Therapy

Thailand
University of North Carolina, Chapel Hill
National Institute of Allergy and Infectious Diseases (NIAID); Merck Sharp... and other collaborators

Completed

The Effect of Vorinostat on HIV RNA Expression in the Resting CD4+ T Cells of HIV+ Pts on Stable ART

HIV-1 Infection

United States
Cytheris SA

Completed

Safety Study of IL-7 in HIV-infected Patients (Inspire)

HIV Infections | Lymphopenia

United States, France, Canada, Italy
Centre Hospitalier Universitaire de Saint Etienne

Completed

Impact of Pre-ART Blood CD4+ T Cell Level on the Rectal Reservoir in Long-term HIV-1 Treated Men (VIRECT)

Human Immunodeficiency Virus

France
Tehran University of Medical Sciences

Unknown

The Study of the Effects of Vitamin A on Immune System in Patients With Atherosclerosis

Atherosclerosis

Iran, Islamic Republic of
Bristol-Myers Squibb

Completed

A Comparison of Epivir Plus Crixivan Combined With Zerit or Retrovir in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs

HIV Infections

United States, Puerto Rico
Merck Sharp & Dohme LLC

Unknown

Safety and Effectiveness of Giving Indinavir, Ritonavir, Stavudine, and Lamivudine to HIV-Infected Patients Who Have Never Received Anti-HIV Drugs

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Study to Evaluate the Effects of Interleukin-12 (rhIL-12) in HIV-Positive Patients With CD4 Cell Counts Less Than 50 Cells/mm3 or 300-500 Cells/mm3

HIV Infections

United States
Kirby Institute

Completed

Antiretroviral Therapy Intensification With Raltegravir or Addition of Hyper-immune Bovine Colostrum in HIV-1 Infected Patients With Suboptimal CD4+ T Cell Response (CORAL)

HIV Infections
Agouron Pharmaceuticals

Unknown

Effectiveness of Treating HIV-Positive Patients With an HIV Vaccine (Remune)

HIV Infections

United States
Elizabeth Glaser Pediatric AIDS Foundation
Ministry of Health, Mozambique

Completed

Evaluating the Effectiveness of Point-of-care Diagnostic Technologies in MCH Services in Mozambique

HIV | Syphilis | Anemia During Pregnancy
Copenhagen University Hospital at Herlev
University Hospital, Gentofte, Copenhagen

Unknown

Can Methylprednisoloneacetate Prevent Seroma After Mastectomy for Primary Breast Cancer

Breast Cancer

Denmark
National Institute of Allergy and Infectious Diseases...

Completed

A Study of Immune System Activity in Healthy Adults

HIV Infections | HIV Seronegativity

United States
National Institute of Allergy and Infectious Diseases...
Chiron Corporation

Completed

An International Study to Evaluate Recombinant Interleukin-2 in HIV Positive Patients Taking Anti-retroviral Therapy (ESPRIT)

HIV Infections

United States, Brazil, Australia, Argentina, Austria, Belgium, Canada, Denmark, France, Germany, Ireland, Israel, Italy, Japan, Morocco, Netherlands, Norway, Poland, Portugal, Singapore, Spain, Sweden, Switzerland, Thailand, United Kingdom
Bristol-Myers Squibb

Completed

A Comparison of Two Anti-HIV Triple-Drug Combinations in HIV-Infected Patients

HIV Infections

United States, Puerto Rico
Glaxo Wellcome

Completed

The Safety and Effectiveness of Lamivudine Plus Zidovudine, Used With and Without 1592U89, in HIV-1 Infected Patients Who Have Never Taken Anti-HIV Drugs

HIV Infections

United States, Canada, Puerto Rico
National Institute of Allergy and Infectious Diseases...

Completed

Effect of Leflunomide on T Cell Proliferation in HIV-Infected Patients

HIV Infections

United States
University of California, San Francisco
Merck Sharp & Dohme LLC

Completed

Raltegravir Intensification in HIV-infected Patients

HIV Infections

United States
Affini-T Therapeutics, Inc.

Recruiting

Phase I Study of Autologous CD8+ and CD4+ Engineered T Cell Receptor T Cells in Subjects With Advanced or Metastatic Solid Tumor

Colorectal Cancer | Non-Small Cell Lung Cancer | Solid Tumor | Pancreatic Ductal Adenocarcinoma | KRAS G12V

United States
Centre Leon Berard
Ministry of Health, France; Cytheris, Inc.

Completed

Study Evaluating Impact of IL-7 on CD4 Lymphopenia, Risks of Severe Haematological Toxicity and Tumor Progression in Metastatic Breast Cancer Patients

Metastatic Breast Cancer

France
National Institute of Allergy and Infectious Diseases...

Completed

A Multicenter, Prospective, Randomized, Double-Blind, Placebo-Controlled Trial of Three Preparations of Low-Dose Oral Alpha Interferon in HIV-Infected Patients With CD4+ Counts >= 50 and <= 350 Cells/mm3

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

Evaluation of the Safety and Tolerance of Immunotherapy With Autologous, Ex-Vivo Expanded, HIV-Specific Cytotoxic T-Cells in HIV-Infected Patients With CD4+ Counts Between 100-400/mm3

HIV Infections

United States
Pharmacia and Upjohn

Completed

A Double-Blind, Randomized, Comparative Study of Delavirdine Mesylate (U-90152S) in Combination With Didanosine (ddI) Versus ddI Alone in HIV-1 Infected Individuals With CD4 Counts of <= 300/mm3

HIV Infections

United States, Puerto Rico
National University, Rwanda
University of Pittsburgh; Brown University; Centers for Disease Control and Prevention and other collaborators

Unknown

Evaluation of Clinical Impacts and Costs of eHealth in Rwanda

Clinical Decision Support System | HIV/AIDS and Infections | Electronic Medical Records

Rwanda
National Institute of Allergy and Infectious Diseases...

Completed

A Phase II Study of Intermittent Recombinant Human Interleukin-2 (rhIL-2) by Intravenous or Subcutaneous Administration in Subjects With HIV Infection on Highly Active Antiretroviral Therapy (HAART) Compared to HAART Alone

HIV Infections

United States
Pharmacia and Upjohn

Completed

A Study to Find the Best Dosing Schedule for Delavirdine, Zidovudine, and Indinavir in HIV-Positive Patients

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

Active Immunization of HIV-1 Infected, Pregnant Women With CD4 Lymphocyte Counts >= 400/mm3: A Phase I Study of Safety and Immunogenicity of VaxSyn Recombinant gp160 (NOTE: Some Patients Receive Placebo)

HIV Infections | Pregnancy | HIV Seronegativity

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Study of the Long-Term Outcomes of HIV-Positive Patients

HIV Infections

United States
University of California, San Francisco

Completed

Trial Embedded in an Electronic Personal Medical Health Records

HIV Infections | Health Literacy

United States
Otsuka America Pharmaceutical

Completed

A Phase I Study of Three Doses of OPC-8212 (Vesnarinone) in HIV-Infected Persons With CD4+ Cell Number > 300 Cells/mm3

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Multicenter Study To Determine Foscarnet Dose Response in HIV Infected Patients With PGL and/or Constitutional Disease

HIV Infections

United States
Aaron Diamond AIDS Research Center

Unknown

A Study of Tucaresol in HIV-Infected Patients Who Are Taking Other Anti-HIV Drugs

HIV Infections

United States
Institute for Interdisciplinary Infectiology
Hoffmann-La Roche

Unknown

Cohort Study for Patients Using Fuzeon (Enfuvirtide)

HIV Infections | Antiretroviral Treatment

Germany
Beijing Tongren Hospital

Completed

Distinct Response of CD4+CD25+Foxp3+ and IL-10-secreting Type I T Regulatory Cells to Cluster Specific Immunotherapy in Allergic Rhinitis Children

Allergic Rhinitis | Effects of Immunotherapy

China
CytoDyn, Inc.

Completed

Observational Study of Blood Treated With Cytolin

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Glaxo Wellcome

Completed

Pilot Study to Evaluate the Efficacy of Zidovudine in Preventing CD4+ Lymphocyte Decline in Patients With Primary HIV Infection. (One Treatment Arm Receives Placebo)

HIV Infections

United States

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