Search clinical trials for: Digestive enzymes

Total 54436 results

Novartis Pharmaceuticals

Completed

Imatinib Mesylate in Patients With Various Types of Malignancies Involving Activated Tyrosine Kinase Enzymes

Chronic Myelomonocytic Leukemia | Hypereosinophilic Syndrome | Systemic Mastocytosis | Dermatofibrosarcoma

Australia
Yonsei University

Completed

Weight Loss Effect on Circulating Liver Enzymes

Liver Dysfunction | Visceral Fat

Korea, Republic of
University of Helsinki

Completed

Randomised Open-label Multicenter Study Evaluating Ciprofloxacin in Severe Alcoholic Hepatitis

Alcoholic Hepatitis | Alcoholic Cirrhosis

Finland
Xijing Hospital of Digestive Diseases

Completed

Helicobacter Pylori Eradication With Berberine Quadruple Therapy Versus Clarithromycin Quadruple Therapy

Gastritis | Dyspepsia | Peptic Ulcer

China
Korea University
Kyungpook National University Hospital; Soon Chun Hyang University; Sungkyunkwan...

Completed

Norfloxacin Versus Ciprofloxacin for Spontaneous Bacterial Peritonitis (SBP) Prevention

Adverse Reaction to Other Drugs and Medicines

Korea, Republic of
University Hospital, Lille
Ministry of Health, France

Terminated

Effect of Fluconazole on the Levels of ASCA After Surgical Resection for Crohn's Disease. (AscaMC)

Crohn's Disease Aggravated

France
University of Miami

Completed

Fluconazole in Preventing Mucositis in Patients Undergoing Radiation Therapy for Head and Neck Cancer

Head and Neck Cancer | Infection | Oral Complications

United States
AbbVie

Completed

Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir Co-Administered With Sofosbuvir With and Without Ribavirin in Treatment-Naive HCV Genotype 1-Infected Adults

Chronic Hepatitis C Virus (HCV Infection Genotype 1)
Unity Health Toronto
University of Toronto

Completed

A Pilot Study of Norfloxacin for Hepatopulmonary Syndrome

Hepatopulmonary Syndrome

Canada
AbbVie

Withdrawn

Study of Ombitasvir/Paritaprevir/Ritonavir in Japanese Adults With Genotype 1b Chronic Hepatitis C Virus (HCV) Infection With End Stage Renal Disease (ESRD) on Hemodialysis (HD) (GIFT-R)

Chronic Hepatitis C Virus
Uniformed Services University of the Health Sciences
Naval Medical Research Center; Navy Bureau of Medicine and Surgery; Ministry... and other collaborators

Terminated

Trial Evaluating Ambulatory Treatment of Travelers' Diarrhea (TrEAT TD)

Acute Watery Diarrhea | Dysentery/Febrile Diarrhea

Afghanistan, Djibouti, Honduras, Kenya, Thailand
Hoffmann-La Roche

Completed

Exploratory Study to Assess the Short Term Effect on Liver Enzymes and the Safety of TRO19622 in Patients With Non-Alcoholic Steatohepatitis (NASH)

Non-Alcoholic Steatohepatitis (NASH)

France
Hoffmann-La Roche

Completed

A Study of RO5024048 in Combination With Ritonavir-Boosted Danoprevir With or Without Copegus (Ribavirin) in Interferon-Naïve Patients With Chronic Hepatitis C Genotype 1 (INFORM-SVR)

Hepatitis C, Chronic

France, Germany, United States, New Zealand
Hoffmann-La Roche

Completed

A Study of Danoprevir/Ritonavir and Copegus With RO5024048 and/or Pegasys in Patients With Chronic Hepatitis C

Hepatitis C, Chronic

United States, Spain, France, Canada, Germany, Austria, Australia, Brazil, United Kingdom, Italy, Mexico, Poland, Puerto Rico
Hoffmann-La Roche

Completed

ANNAPURNA: A Study of The Combination of RO5466731, RO5190591, Ritonavir and Copegus (Ribavirin) With or Without RO5024048 in Patients With Chronic Hepatitis C Who Are Either Treatment-Naïve or Have Previously Experienced a Null Response to Interferon-Based Treatment

Hepatitis C, Chronic

United States, New Zealand, Germany, Australia, Poland
Hoffmann-La Roche

Completed

A Study of Ritonavir-Boosted Danoprevir in Combination With Pegasys (Peginterferon Alfa-2a) and Copegus (Ribavirin) in Patients of Asian Origin With Chronic Hepatitis C Genotype 1 With or Without Cirrhosis

Hepatitis C, Chronic

Taiwan, Korea, Republic of, Thailand
Hoffmann-La Roche

Completed

A Study of Danoprevir Boosted With Low Dose Ritonavir in Combination With Pegasys and Copegus in Treatment-Naive Patients With Chronic Hepatitis C Virus Infection

Hepatitis C, Chronic

France, Germany, United States, Spain, Canada, Austria, United Kingdom, Puerto Rico, Italy, Brazil, Mexico
Hoffmann-La Roche

Withdrawn

A Study of RO5024048 in Combination With Ritonavir-Boosted Danoprevir and Pegasys/Copegus in Patients With Chronic Hepatitis C Genotype 1 Who Have Failed Prior HCV Protease Inhibitor Treatment

Hepatitis C, Chronic
Hoffmann-La Roche

Completed

A Study of Ritonavir-Boosted Danoprevir (RO5190591) in Combination With Pegasys and Ribavirin in Patients With Chronic Hepatitis C Genotype 1

Hepatitis C, Chronic

New Zealand, Poland, France
University of Modena and Reggio Emilia

Unknown

Efficacy Study to Evaluate the Effect of New Antiviral Drugs on HCV Infection.

Chronic Hepatitis, C Virus

Italy
National Taiwan University Hospital

Unknown

Symptom Assessment for Patients With Gastro-esophageal Reflux Disease Receiving Helicobacter Pylori Eradication

Gastroesophageal Reflux Disease

Taiwan
University of Pittsburgh
National Institute of Mental Health (NIMH)

Completed

PET Imaging Study of Recovered Anorexics

Anorexia Nervosa

United States
McGill University Health Centre/Research Institute...
Merck Sharp & Dohme LLC; CIHR Canadian HIV Trials Network

Completed

Raltegravir Switch Study to Reduce Liver Fibrosis Progression in HIV-Hepatitis C Co-infection

Hepatitis C | HIV | Liver Fibrosis

Canada
King Faisal Specialist Hospital & Research Center

Completed

Levofloxacin-Doxycycline for Helicobacter Pylori Eradication in Saudi Arabia

GASTRITIS
Hoffmann-La Roche

Completed

A Study of Ritonavir-Boosted Danoprevir and RO5024048 in Different Combinations in Null Responder or Treatment-Naïve Patients With Chronic Hepatitis C and Compensated Cirrhosis

Hepatitis C, Chronic

United States, Canada, Slovakia, Poland, New Zealand, France, Australia
Taizhou Hospital
First Affiliated Hospital of Zhejiang University; Taizhou First People's Hospital and other collaborators

Unknown

A Multi-center Study for Eradication of Refractory Helicobacter Pylori

Gastritis

China
AbbVie (prior sponsor, Abbott)

Completed

A Study to Evaluate Paritaprevir With Ritonavir (ABT-450/r) When Given Together With Ombitasvir and With and Without Ribavirin (RBV) in Treatment-Naïve Participants With Genotype 1, 2 or 3 Chronic Hepatitis C Virus (HCV) (Navigator)

Hepatitis C Virus
AbbVie

Completed

A Study to Evaluate Chronic Hepatitis C Virus (HCV) Infection in Cirrhotic Adults With Genotype 1b (GT1b) Infection (Turquoise-IV)

Chronic Hepatitis C Virus (HCV) Infection
First Affiliated Hospital Xi'an Jiaotong University
Second Affiliated Hospital of Xi'an Jiaotong University; 3201 Hospital in Hanzhong

Unknown

Clinical Trial Comparing ERAT vs Antibiotic Therapy vs Appendectomy for Treatment of Uncomplicated Acute Appendicitis

Acute Appendicitis

China
University of Pittsburgh
Solvay Pharmaceuticals

Completed

Pancreatic Enzymes to Restore Digestive Function in Malnourished Gastric Bypass Patients

Obesity

United States
Emory University

Completed

Paroxetine for the Treatment of Interferon Related Side Effects for Hepatitis C

Depression | Hepatitis C | Interferon-alpha Associated Side Effects
Asofarma de México S.A de C.V.
Hospital Ángeles, Clínica Londres, Mexico City; Centro InmunoQ, Mexico City; Torre... and other collaborators

Completed

Triple Therapy Versus Levofloxacin-based Therapy for Helicobacter Pylori Eradication in Mexico.

Helicobacter Pylori Gastritis
National Health Research Institutes, Taiwan
National Taiwan University Hospital; China Medical University Hospital; Chang... and other collaborators

Completed

Prospective Study of First-line Antibiotic Therapy for Early-stage Gastric MALT Lymphoma for Treatment Outcome

Gastric MALT Lymphoma

Taiwan
King Saud University

Completed

Prophylaxis for Aspiration of Gastric Contents.

Pulmonary Aspiration of Gastric Contents
AstraZeneca

Completed

High Dose Esomeprazole Na for Prevention of Rebleeding After Successful Endoscopic Therapy of a Bleeding Peptic Ulcer

Bleeding Peptic Ulcer

China
Kaiser Permanente

Completed

A Pilot Study on the Use of Prophylactic Antibiotics for EUS-guided Pancreatic Cyst Aspiration

Pancreatic Cysts

United States
Abbott

Completed

A Double-blind, Randomized, Multicenter, Cross-over Study to Compare the Effect of Creon N and Creon® on Fat Digestion in Subjects ≥ 12 Years of Age With Pancreatic Exocrine Insufficiency Due to Cystic Fibrosis

Pancreatic Exocrine Insufficiency Due to Cystic Fibrosis

Hungary, Spain
Merck Sharp & Dohme LLC

Completed

To Evaluate the Effect of Ritonavir or Omeprazole on the Pharmacokinetics of Samatasvir (IDX719) in Healthy Participants (MK-1894-006)

Chronic Hepatitis C Infection
Janssen R&D Ireland

Completed

A Study to Evaluate the Safety, Tolerability, and Effectiveness of a 12-Week Combination Therapy of TMC647055 and TMC435 With and Without GSK23336805 With a Pharmacokinetic Enhancer With and Without Ribavirin in Patients Infected With Chronic Genotype 1 Hepatitis C Virus

Chronic Hepatitis C

Belgium, Germany
Assistance Publique - Hôpitaux de Paris

Terminated

Norfloxacin Therapy for Patients With Cirrhosis and Severe Liver Failure (NORFLOCIR)

Cirrhosis

France
University of Alberta
Canadian Institutes of Health Research (CIHR); Gilead Sciences; Abbott

Completed

Highly Active Antiretroviral Therapy for Patients With Primary Biliary Cirrhosis (HAART)

Primary Biliary Cirrhosis

Canada
Bristol-Myers Squibb

Completed

Study Assessing the Effects of Darunavir/Ritonavir or Lopinavir/Ritonavir on the Pharmacokinetics of Daclatasvir in Healthy Participants

Hepatitis C

United States
Tang-Du Hospital

Unknown

Deep Brain Stimulation of Nucleus Accumbens to Treat Severe Anorexia Nervosa

Anorexia Nervosa

China
Seattle Children's Hospital
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Cystic...

Completed

Baby Observational and Nutritional Study (BONUS)

Cystic Fibrosis | Growth Failure | Exocrine Pancreatic Insufficiency

United States
Canadian Network for Observational Drug Effect...
Canadian Institutes of Health Research (CIHR); Drug Safety and Effectiveness...

Completed

Proton Pump Inhibitors and Risk of Community-acquired Pneumonia

Gastroesophageal Reflux Disease (GERD) | Community-acquired Pneumonia

Canada
Xijing Hospital of Digestive Diseases

Completed

Helicobacter Pylori Eradication With Berberine Quadruple Therapy Versus Bismuth-containing Quadruple Therapy

Gastritis | Dyspepsia | Peptic Ulcer

China
National Nutrition and Food Technology Institute

Unknown

The Effect of Synbiotics Supplement on Lipid Profile, Liver Enzymes, Inflammatory Factors and Hepatic Fibrosis in Lean and Normal Weight Patients With Nonalcoholic Fatty Liver

Non Alcoholic Steatohepatitis

Iran, Islamic Republic of
University Hospital, Bonn
Dr. Axel Baumgarten, Berlin; Dr. Christoph Stephan, Frankfurt/M; Dr. Stefan Esser... and other collaborators

Withdrawn

Safety Study of Raltegravir in HIV/HCV Co-infected Patients

Hepatitis C | HIV

Germany
IRCCS Burlo Garofolo

Completed

A Randomized Controlled Trial on Antibiotic Prophylaxis in Children With Vesico-Ureteral Reflux

Pyelonephritis | Renal Scars

Italy
Merck Sharp & Dohme LLC
Janssen Research & Development, LLC

Completed

Samatasvir (IDX719) in Combinations With Simeprevir and/or TMC647055/Ritonavir With or Without Ribavirin for 12 Weeks in Participants With Chronic Hepatitis C Infection (MK-1894-005)

Chronic Hepatitis C Virus

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