Search clinical trials for: Donor specific Antibody

Total 12976 results

Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Alemtuzumab, Fludarabine Phosphate, and Total-Body Irradiation Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer

Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell... and other conditions

United States, Italy
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Fludarabine and Total-Body Irradiation Followed By Donor Stem Cell Transplant and Cyclosporine and Mycophenolate Mofetil in Treating HIV-Positive Patients With or Without Cancer

HIV Infection | Unspecified Childhood Solid Tumor, Protocol Specific | Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal... and other conditions

United States
University of Louisville
Penn State University

Completed

Vaccine Therapy in Treating Patients Who Have Undergone a Donor Stem Cell Transplant and Have Cytomegalovirus Infection That Has Not Responded to Therapy

Cancer

United States
University of Roma La Sapienza

Completed

Safety, Immunogenicity And Efficacy Of Vaccination In Military Personnel

Vaccination Failure | Vaccination Adverse Events | Specific Antibody Response

Italy
Xijing Hospital of Digestive Diseases
Shanghai Tongji Hospital, Tongji University School of Medicine; First Affiliated...

Unknown

Mesalazine With Hydrocortisone Sodium Succinate Enema for 4-Week Treatment in Patients With Ulcerative Colitis

Ulcerative Colitis, Unspecified

China
David Rizzieri, MD

Completed

Safety Trial of NK DLI From 6/6 HLA Matched Family Member Following Nonmyeloablative ASCT

Lymphoma

United States
Ningbo Cancer Hospital

Unknown

PD-1 Antibody Expressing CAR T Cells for Mesothelin Positive Advanced Malignancies

Advanced Cancer | Solid Tumor, Adult

China
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Withdrawn

Donor White Blood Cell Infusion in Treating Patients With Metastatic or Unresectable Cancer

Unspecified Childhood Solid Tumor, Protocol Specific | Unspecified Adult Solid Tumor, Protocol Specific
Cedars-Sinai Medical Center

Completed

A Safety Study of Tocilizumab to Improve Transplant Rates in Highly Sensitized Patients Awaiting Kidney Transplantation

End Stage Renal Disease (ESRD)

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Interleukin-2 Plus Monoclonal Antibody Therapy in Treating Patients With Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific

United States
Baylor College of Medicine
M.D. Anderson Cancer Center; Massachusetts General Hospital; National Heart,... and other collaborators

Completed

Most Closely HLA Matched Allogeneic Virus Specific Cytotoxic T-Lymphocytes (CTL) (CHALLAH)

EBV Infection | Adenovirus Infection

United States
Radboud University Medical Center
Gilead Sciences

Completed

Imaging Colo-rectal Cancer Using a Two Step Antibody Technique in Nuclear Imaging

Colonic Neoplasms

Netherlands
Novo Nordisk A/S

Completed

Special Survey of Production of Insulin Aspart Specific Antibody

Diabetes Mellitus, Type 2 | Diabetes | Diabetes Mellitus, Type 1

Japan
Hoffmann-La Roche

Completed

A Prospective Study to Evaluate the Specificity of the Cobas TaqScreen MPX Test for Use on the Cobas s 201 System for Screening Plasma Pools From Source Plasma Donors for the Presence of HBV DNA, HCV RNA, and HIV-1 RNA

Healthy Volunteer

United States
Seoul National University Hospital

Unknown

Immunotherapy in Intractable Cryptogenic Epilepsy Patients With Autoimmune Antibody

Epilepsy, Unspecified, Intractable

Korea, Republic of
Japan Blood Products Organization

Completed

The Desensitization Therapy With GB-0998 for Anti-donor Antibody-positive Recipients.

End Stage Renal Disease

Japan
Morphotek
National Cancer Institute (NCI); Children's Oncology Group

Completed

MORAb-004 in Treating Young Patients With Recurrent or Refractory Solid Tumors or Lymphoma

Unspecified Childhood Solid Tumor, Protocol Specific | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma and other conditions

United States
Mark Stegall
Millennium Pharmaceuticals, Inc.

Terminated

Impact of Proteasome Inhibition on Anti-Donor HLA Antibody Production After Kidney Transplantation

Disorder of Transplanted Kidney

United States
Novartis Pharmaceuticals
PRINTO / PRCSG

Withdrawn

An Open-label, Multi-arm, Non-comparative Safety and Tolerability Study of Canakinumab (ACZ885) in Patients With Active Systemic Juvenile Idiopathic Arthritis (SJIA) (β-SPECIFIC 4Pa)

Systemic Juvenile Idiopathic Arthritis
Universitaire Ziekenhuizen KU Leuven
KU Leuven

Unknown

Polysaccharide Antibody Response Study (PARS)

Specific Polysaccharide Antibody Deficiency

Belgium
Mayo Clinic
Alexion Pharmaceuticals

Terminated

Eculizumab to Prevent Antibody-mediated Rejection in ABO Blood Group Incompatible Living Donor Kidney Transplantation (ABOi)

Kidney Transplant

United States
International Maternal Pediatric Adolescent AIDS...
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

IMPAACT P1085: Human Papilloma Virus (HPV) Type-Specific Antibody (HPV)

Papilloma Virus, Human

United States, Puerto Rico
Medical University of Vienna

Completed

6-year Antibody Check After Third Vaccination Against Japanese Encephalitis

Post Other Specified Vaccination Encephalitis

Austria
Instituto Mexicano del Seguro Social

Completed

Anti-inflammatory Effect of Atorvastatin on Graft Donor Kidney

Renal Insufficiency

Mexico
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Completed

Giving Epstein-Barr Virus (EBV) Specific Killer T Lymphocytes to Patients Who Have Had Donor Marrow Grafts (ETNA)

Epstein-Barr Virus Infections

United States
Yonsei University
Astellas Pharma Korea, Inc.

Completed

Graft Rejection or Tolerance Affected by Serial Change of Anti-donor Lymphocyte Antibody After Liver Transplantation

Liver Transplant Rejection

Korea, Republic of
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Completed

Safety, Toxicity and MTD of One Intravenous IV Injection of Donor CTLs Specific for CMV and Adenovirus (ACT-CAT)

Cytomegalovirus Infection | Adenovirus Infection

United States
University of Minnesota

Completed

A Structured Walking Program or Standard Therapy in Cancer Patients Undergoing a Donor Bone Marrow Transplant

Cancer
Novartis
Novartis Vaccines

Withdrawn

Antibody Levels Associated With Reduced Risk of Invasive Group B Streptococcus Disease in Infants Aged Less Than 90 Days

Invasive Group B Streptococcus Disease

South Africa
National Cancer Institute (NCI)

Completed

IMC-A12 in Treating Young Patients With Relapsed or Refractory Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor or Other Solid Tumor

Unspecified Childhood Solid Tumor, Protocol Specific | Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor

United States
National Cancer Institute (NCI)

Completed

Selumetinib and Cetuximab in Treating Patients With Refractory Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific | Recurrent Colon Cancer | Recurrent Rectal Cancer | Stage IVA Colon Cancer | Stage IVA Rectal Cancer | Stage IVB Colon Cancer | Stage IVB Rectal Cancer

United States
University of Southern California

Completed

Novel Adjuvants for Peptide-Based Melanoma Vaccines

Melanoma

United States
University of Wisconsin, Madison
Novartis Pharmaceuticals

Terminated

Mycophenolic Acid (MPA) Monotherapy in Liver Transplantation

Liver Transplant

United States
National Cancer Institute (NCI)

Completed

Cixutumumab and Temsirolimus in Treating Younger Patients With Solid Tumors That Have Recurred or Not Responded to Treatment

Unspecified Childhood Solid Tumor, Protocol Specific

United States, Canada
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); Seagen Inc.

Withdrawn

Brentuximab Vedotin After Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Hematopoietic/Lymphoid Cancer

United States
National Cancer Institute (NCI)

Completed

Sunitinib Malate and Bevacizumab in Treating Patients With Kidney Cancer or Advanced Solid Malignancies

Clear Cell Renal Cell Carcinoma | Unspecified Adult Solid Tumor, Protocol Specific | Stage III Renal Cell Cancer | Stage IV Renal Cell Cancer | Recurrent Renal Cell Cancer | Stage I Renal Cell Cancer | Stage II Renal Cell Cancer

United States
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Withdrawn

Donor T Cells, Low-Dose Aldesleukin, and Low-Dose GM-CSF After Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma

Lymphoma
Josep M Grinyo
Carlos III Health Institute

Completed

Selection of Immunosuppression in Kidney Transplant Recipients Depending on Pre-transplant Donor-specific T-cell Reactivity. (SIRES)

Disorder Related to Renal Transplantation

Spain
National Cancer Institute (NCI)

Completed

Bevacizumab and Sunitinib in Treating Patients With Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific

United States
National Cancer Institute (NCI)

Completed

Bevacizumab and Cediranib Maleate in Treating Patients With Metastatic or Unresectable Solid Tumor, Lymphoma, Intracranial Glioblastoma, Gliosarcoma or Anaplastic Astrocytoma

Unspecified Childhood Solid Tumor, Protocol Specific | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma and other conditions

United States
Chulalongkorn University

Unknown

Hepatitis B Antigen Kidney Graft Into Protective Level Hepatitis B Antibody Recipients

HBsAg(+) Donor Kidney Allograft | HBsAg(-) Donor Kidney Allograft

Thailand
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Withdrawn

Monoclonal Antibody Therapy in Treating Patients With Advanced Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific
Favrille

Suspended

GM-CSF With or Without Vaccine Therapy After Combination Chemotherapy and Rituximab as First-Line Therapy in Treating Patients With Stage II, Stage III, or Stage IV Diffuse Large B-Cell Lymphoma

Lymphoma

United States
Milton S. Hershey Medical Center
National Cancer Institute (NCI)

Unknown

Emergency Use of Donor Lymphocytes in Treating Patients Who Have Undergone Donor Stem Cell Transplant and Have Cytomegalovirus Infections

Cancer

United States
Progenics Pharmaceuticals, Inc.

Completed

Extended Study of Prostate-specific Membrane Antigen Antibody-Drug Conjugate in Subjects With Prostate Cancer

Prostate Cancer

United States
St. Vincent Medical Center - Los Angeles

Unknown

Monoclonal Antibody Plus Cyclophosphamide in Treating Patients With Metastatic Cancer

Unspecified Adult Solid Tumor, Protocol Specific

United States
Progenics Pharmaceuticals, Inc.

Completed

Prostate-specific Membrane Antigen Antibody-Drug Conjugate in Subjects With Prostate Cancer

Prostate Cancer

United States
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI)

Unknown

Carbendazim in Treating Patients With Advanced Solid Tumors or Lymphoma

Lymphoma | Unspecified Adult Solid Tumor, Protocol Specific
Milton S. Hershey Medical Center

Completed

Donor Stem Cell Transplant in Treating Young Patients With Relapsed or Refractory Solid Tumors

Sarcoma | Unspecified Childhood Solid Tumor, Protocol Specific | Neuroblastoma

United States
National Cancer Institute (NCI)

Completed

Bevacizumab in Treating Young Patients With Refractory Solid Tumors

Unspecified Childhood Solid Tumor, Protocol Specific

United States

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