Search clinical trials for: EGFR uncommon/ single mutation Phase 2, Phase 2b, Phase II Exon 20

Total 98715 results

Icahn School of Medicine at Mount Sinai
Eiger BioPharmaceuticals

Withdrawn

Interferon Lambda Therapy for COVID-19

SARS-CoV-2
Hunan Province Tumor Hospital

Recruiting

Survival Outcome of EGFR-TKI in Uncommon EGFR Mutant Advanced NSCLC

Non-small Cell Lung Cancer

China
Dana-Farber Cancer Institute
Genentech, Inc.

Recruiting

A Single Arm Phase II Study of ADjuvant Endocrine Therapy, Pertuzumab, and Trastuzumab for Patients With Anatomic Stage I Hormone Receptor-positive, HER2-positive Breast Cancer (ADEPT)

Breast Cancer | HER2-positive Breast Cancer | Hormone Receptor Positive Breast Cancer | Invasive Carcinoma of the Breast | Node Negative Breast Cancer | Micrometastasis Breast Cancer

United States
Yooyoung Pharmaceutical Co., Ltd.

Completed

Clinical Trial to Assess the Efficacy and Safety of YYD601 in NERD Patients

Non-erosive Reflux Disease

Korea, Republic of
Allist Pharmaceuticals, Inc.

Withdrawn

Phase Ib Study of FURMONERTINIB in Patients With NSCLC Having Exon 20 Insertion Mutation

NSCLC

China
ArriVent BioPharma, Inc.
Allist Pharmaceuticals, Inc.

Recruiting

Study to Compare Furmonertinib to Platinum-Based Chemotherapy for Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) With Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion Mutations (FURVENT)

Advanced Non-Small Cell Lung Cancer | Metastatic Non-Small Cell Lung Cancer | EGFR Exon 20 Mutations

United States, Australia, Spain, France, Italy, China, Japan, Korea, Republic of, Malaysia, Netherlands, Philippines, Singapore, Taiwan, Thailand, Brazil, Israel, United Kingdom, Mexico
Unity Health Toronto

Not yet recruiting

Optimal Resection Technique for Medium-sized (10-20mm) Colorectal Polyps

10-20mm Colorectal Polyp
Urovant Sciences GmbH
Ion Channel Innovations

Completed

Phase 1 Study With OAB Assessing the Safety and Activity of hMaxi-K Gene Transfer (OAB)

Overactive Bladder

United States
Indiana University

Completed

Interactions of Fronto-Parietal High Frequency rTMS on Anterior Cingulate Cortex Activation in Schizophrenia (rTMS-FPCC)

Schizophrenia

United States
Yonsei University

Unknown

The Influence of Head and Neck Position on the Cuff Pressure Using Nasotracheal Tube

Adult Patients Over 20 Years of Age Who Require Intubation of the Nasotracheal Tube to Undergo Oral and Maxillofacial Surgery Under General Anesthesia

Korea, Republic of
Chengdu Kanghong Pharmaceutical Group Co., Ltd.

Recruiting

Phase 1 Study of KH607 Tablets

Healthy

China
Leiden University Medical Center
Novo Nordisk A/S

Completed

Effect of Liraglutide on Cardiovascular Endpoints in Diabetes Mellitus Type 2 Patients of South Asian Descent (MAGNA VICTORIA)

Cardiovascular Disease | Fatty Liver | Metabolic Syndrome | Diabetes Mellitus Type 2 | Diastolic Dysfunction

Netherlands
Groupe Français de Pneumo-Cancérologie

Recruiting

Mechanisms of Resistance to Amivantamab in Patients With NSCLC With EGFR Exon 20 Insertion (RESAMEX)

Non-small Cell Lung Cancer | EGFR Exon 20 Insertion Mutation

France
EyePoint Pharmaceuticals, Inc.
Medical Technology Enterprise Consortium (MTEC)

Terminated

Evaluation of the Safety and Efficacy of Razuprotafib in Hospitalized Subjects With Coronavirus Disease 2019 (RESCUE)

COVID-19 | Acute Respiratory Distress Syndrome (ARDS)

United States
University of New Mexico

Completed

Study of Aerosolized Liposomal 9-Nitro-20 (S)- Camptothecin (L9NC)

Lung Diseases | Cancer

United States
Chugai Pharmaceutical
Japan Lung Cancer Society

Completed

The Biomarker Exploratory Study in Prospective Multicenter Observational Study of Atezolizumab Combination Therapy in Lung Cancer (J-TAIL-2)

Non-small Cell Lung Cancer | Extensive Disease Small Cell Lung Cancer

Japan
Zeno Alpha Inc.

Completed

A Study of ZN-c5 in Subjects With Breast Cancer

Breast Cancer

United States, Belarus, Bosnia and Herzegovina, Czechia, Hungary, Lithuania, Russian Federation, Serbia, Ukraine
Black Diamond Therapeutics, Inc.

Recruiting

Phase 1/2 Study of BDTX-1535 in Patients With Glioblastoma or Non-Small Cell Lung Cancer With EGFR Mutations

Non-Small Cell Lung Cancer | NSCLC | Metastatic Lung Cancer | Metastatic Lung Non-Small Cell Carcinoma | EGF-R Positive Non-Small Cell Lung Cancer | Advanced Lung Carcinoma | EGFR-TKI Resistant Mutation | Advanced Non-Small Cell Squamous Lung Cancer | Epidermal Growth Factor Receptor C797S | Epidermal...

United States
Kyuzi Kamoi

Not yet recruiting

20 Years Results by HBP and DBP in Patients With Type 2 Diabetes Mellitus After Following-up

Diabetes Mellitus
University Hospital Freiburg
Essex Pharma GmbH

Completed

Effect of Ezetimibe or Simvastatin or Both on Low Densitiy Lipoprotein -Subfractions in Patients With Type 2 Diabetes (EZE)

Hypercholesterolemia | Diabetes Mellitus Type 2

Germany
University of Texas Southwestern Medical Center

Withdrawn

Vitamin C for Severe Thermal Injuries

Severe Thermal Injury, Greater Than 20% TBSA

United States
Organ, Tissue, Regeneration, Repair and Replacement
Assistance Publique - Hôpitaux de Paris

Completed

Randomized Double Blinded Study Evaluating CACICOL20 Efficiency Versus Placebo Corneal Chronic Ulcers Healing (UNICOL)

Corneal Ulcer

France
Rio de Janeiro State University

Completed

Study About High Fat Meal and Postprandial Lipemia

Obesity

Brazil
Coloplast A/S

Completed

Assessement of the Peal Force Needed to Peel New Adhesives From the Skin

Ileostomy - Stoma

Denmark
Jiangsu Alphamab Biopharmaceuticals Co., Ltd

Completed

KN026 in Patients With HER2 Expressing Gastric/Gastroesophageal Junction Cancer

Gastric/Gastroesophageal Junction Cancer

China
Institute of Oncology Ljubljana

Unknown

Preoperative Radiotherapy With Capecitabine and Bevacizumab in Locally Advanced Rectal Cancer: CRAB Phase II Study (CRAB)

Locally Advanced Rectal Cancer

Slovenia
Dose Biosystems Inc.

Completed

Effect of a Probiotic Water on Oral Health in Adults

Halitosis | Oral Bacteria

United States
Medical University Innsbruck
TNI Medical AG

Unknown

STIT-2: Evaluation of Safety and Efficacy of Short-time TNI® Treatment in Patients With COPD and Hypercapnia (STIT-2)

COPD | Hypercapnia

Austria, Germany, Switzerland
Q2i, LLC
National Institute on Drug Abuse (NIDA); University of California, Los Angeles

Enrolling by invitation

Technology for MAT in Primary Care - Phase 2

Opioid-use Disorder

United States
AstraZeneca

Completed

A Phase I/III Study of D961H 10 mg and 20 mg in Japanese Paediatric Patients With Gastrointestinal Acid Related Diseases

Zollinger-Ellison Syndrome | Reflux Esophagitis (RE) | Gastric Ulcer (GU) | Duodenal Ulcer (DU) | Anastomotic Ulcer (AU) | Non-erosive Reflux Esophagitis Disease (NERD)

Japan
Advanz Pharma
Astellas Pharma US, Inc.

Completed

Phase III Tolerance and Efficacy Study of RSD1235 in Patients With Atrial Fibrillation (ACT I)

Atrial Fibrillation

United States, Canada, Sweden, Denmark
GlaxoSmithKline

Completed

An Investigation of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GSK2245035 in Healthy Volunteers and Allergic Rhinitics.

Rhinitis, Allergic, Seasonal

Netherlands
Bond Avillion 2 Development LP
Parexel

Active, not recruiting

A Comparison of PT027 vs PT007 Used as Needed in Participants With Asthma

Asthma

United States
LEO Pharma

Completed

A Plaque Test Study With LEO 35299 in Psoriasis Vulgaris

Psoriasis Vulgaris

France
GlaxoSmithKline

Completed

A Bioequivalence Study of Idiazole 20mg DR Tabs and PARIET® 20 mg DR Tabs After a Single Oral Dose Administration Under Fasting Conditions in Healthy Adults

Gastrointestinal Diseases

Egypt
Takeda

Active, not recruiting

TAK-788 as First-Line Treatment Versus Platinum-Based Chemotherapy for Non-Small Cell Lung Cancer (NSCLC) With EGFR Exon 20 Insertion Mutations

Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)

United States, Spain, France, Korea, Republic of, Hong Kong, Australia, Taiwan, United Kingdom, Canada, Turkey, Italy, China, Germany, Japan, Austria, Belgium, Greece, Israel, Netherlands, Portugal, Russian Federation, Singapore, Sw... and more
GlaxoSmithKline
Eisai Inc.

Completed

Single Dose Escalation Trial to Evaluate the Safety, Tolerability Pharmacokinetics and Pharmacodynamics of GSK3050002

Colitis, Ulcerative

United Kingdom
Eleven Biotherapeutics

Completed

Phase 3 Study of EBI-005 in Dry Eye Disease (EBI-005)

Dry Eye Disease (DED)

United States
Hanmi Pharmaceutical Company Limited

Terminated

Phase II Trial of HM61713 for the Treatment of ≥2nd Line T790M Mutation Positive Adenocarcinoma of the Lung

Non Small Cell Lung Cancer

United States, Australia, Italy, Korea, Republic of, Spain, Germany, Malaysia, Taiwan, Canada, Philippines
University Hospital, Bordeaux
Fondation Syndrome de Rubinstein-Taybi

Completed

Rubinstein-Taybi Syndrome: Functional Imaging and Therapeutic Trial (RUBIVAL)

Rubinstein-Taybi Syndrome

France
National Cancer Institute (NCI)

Completed

Sorafenib in Treating Patients With Advanced or Metastatic Cancer of the Urinary Tract

Metastatic Transitional Cell Cancer of the Renal Pelvis and Ureter | Recurrent Bladder Cancer | Recurrent Transitional Cell Cancer of the Renal Pelvis and Ureter | Regional Transitional Cell Cancer of the Renal Pelvis and Ureter | Stage III Bladder Cancer | Stage IV Bladder Cancer | Transitional...

Canada
National Cancer Institute (NCI)

Completed

GTI-2040 and Docetaxel in Treating Patients With Recurrent, Metastatic, or Unresectable Locally Advanced Non-Small Cell Lung Cancer, Prostate Cancer, or Other Solid Tumors

Recurrent Prostate Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Stage IIIA Non-small Cell Lung Cancer | Stage IIIB Non-small Cell Lung Cancer | Stage III Prostate Cancer | Stage IV Prostate Cancer | Recurrent Non-small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer

Canada
University Hospital, Clermont-Ferrand

Unknown

Evaluation of the Protein Intake of the Pregnant Woman According to the Weight Status and in Pregnant Women Operated on Bariatric Surgery (BariaProG)

Pregnant Women From 20 Amenorrhea Weeks

France
University of New Mexico
Baylor College of Medicine

Completed

Phase II Study of Aerosolized Liposomal 9-Nitro-20 (S)- Camptothecin (L9NC)

Endometrial Cancer | Corpus Uteri

United States
Pusan National University Hospital
Pusan National University Yangsan Hospital

Unknown

Nasogastric Tube Insertion Using Cook Airway Exchange Catheter in Anesthetized Patients

Elective Surgery of Gastrointestinal Tract | 100 Adults Aged Between 20 and 70 Years Old | ASA Physical Status of I or II

Korea, Republic of
Hunan Province Tumor Hospital

Completed

Efficacy and Safety of Immunotherapy in Non-small Cell Lung Cancer With Uncommon Histological Type (Esporta)

Uncommon Pathological Types of Lung Cancer

China
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Withdrawn

TK216 and Decitabine in Treating Patients With Relapsed and Refractory Acute Myeloid Leukemia

Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia
Blueprint Medicines Corporation

Active, not recruiting

(Concerto) Study of BLU-451 in Advanced Cancers With EGFR Exon 20 Insertion Mutations

Neoplasms | Neoplasms by Histologic Type | Lung Diseases | Neoplasms by Site | Adenocarcinoma | Carcinoma | Carcinoma, Non-Small-Cell Lung | Respiratory Tract Neoplasms | Carcinoma, Bronchogenic | Bronchial Neoplasms | Metastatic Lung Cancer | Antineoplastic Agents | Brain Metastases | Lung Neoplasm Malignant | EGFR... and other conditions

United States, Canada, Korea, Republic of, Japan, Taiwan
Sanol GmbH

Completed

A Double-blind, Double-dummy, Parallel, Active-controlled, Randomized Trial to Evaluate Efficacy & Safety in Anemia Subjects

Iron Deficiency Anemia

China
Takeda

Withdrawn

A Study to Learn About the Tests Looking for a Gene Mutation in Adults With Lung Cancer in China (ELEGANT) (ELEGANT)

Non-small Cell Lung Cancer (NSCLC)

China

Search clinical trials for: EGFR uncommon/ single mutation Phase 2, Phase 2b, Phase II Exon 20

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