Search clinical trials for: Poly(ADP ribose) polymerases
Total 998 results
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Memorial Sloan Kettering Cancer CenterActive, not recruitingKidney Cancer | Renal Cell Carcinoma | Metastatic Renal Cell Carcinoma | Unresectable Renal Cell CarcinomaUnited States
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Walid Shaib, MDGlaxoSmithKline; Emory UniversityWithdrawnMetastatic Cancer | Cholangiocarcinoma | HRD
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AstraZenecaMerck Sharp & Dohme LLC; GOG Foundation; Myriad Genetic Laboratories, Inc.Active, not recruitingAdvanced Ovarian Cancer | Newly Diagnosed | FIGO Stage III-IV | Partial Response | Complete Response | BRCA Mutation | First Line Platinum ChemotherapyKorea, Republic of, France, Italy, United States, Israel, Canada, China, Brazil, United Kingdom, Poland, Australia, Japan, Netherlands, Russian Federation, Spain
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AstraZenecaMerck Sharp & Dohme LLC; Myriad Genetic Laboratories, Inc.CompletedMetastatic Adenocarcinoma of the Pancreas | Germline BRCA1/2 Mutations andUnited States, France, Italy, Spain, United Kingdom, Belgium, Canada, Germany, Korea, Republic of, Australia, Israel, Netherlands
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National Institute of Allergy and Infectious Diseases...Not yet recruitingCongenital Cytomegalovirus Infection
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Tesaro, Inc.CompletedNeoplasms, BreastUnited States
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AstraZenecaMerck Sharp & Dohme LLC; Myriad Genetic Laboratories, Inc.Active, not recruitingBreast Cancer Metastatic | BRCA 1 Gene Mutation | BRCA 2 Gene MutationItaly, Spain, United States, Czechia, Romania, France, Korea, Republic of, United Kingdom, Hungary, Japan, Peru, Poland, Russian Federation, Turkey, China, Taiwan, Bulgaria, Switzerland, Mexico
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Fox Chase Cancer CenterRecruitingPrimary Myelofibrosis | Polycythemia Vera | Chronic Myelomonocytic Leukemia | Essential Thrombocytosis | Post-polycythemia Vera Myelofibrosis | Post-essential Thrombocythemia MyelofibrosisUnited States
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Guangxi Medical UniversityNot yet recruitingOvarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Carcinoma | High Grade Serous Adenocarcinoma of OvaryChina
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M.D. Anderson Cancer CenterRecruiting
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AGO Research GmbHGlaxoSmithKlineNot yet recruitingPrimary Peritoneal Cancer | Recurrent Ovarian Cancer | Recurrent Fallopian Tube Cancer
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University of OklahomaTesaro, Inc.RecruitingRecurrent Cervix Cancer | Progressive Cervix CancerUnited States
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MedSIRPfizerActive, not recruitingMetastatic Prostate CancerSpain
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Brown UniversityPfizer; LifespanTerminatedOvarian Cancer | Fallopian Tube Cancer | BRCA1 Mutation | BRCA2 Mutation | High Grade Serous CarcinomaUnited States
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BeiGeneCompletedAdvanced or Inoperable Gastric CancerUnited States, Hungary, Spain, China, Hong Kong, Japan, Australia, Taiwan, Belgium, Czechia, Singapore, France, Poland, United Kingdom, Romania, Russian Federation, Georgia
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David Liebner, MDWithdrawnLocally Advanced Leiomyosarcoma | Metastatic Leiomyosarcoma | Unresectable Leiomyosarcoma | Stage III Retroperitoneal Sarcoma AJCC v8 | Stage IIIA Retroperitoneal Sarcoma AJCC v8 | Stage IIIB Retroperitoneal Sarcoma AJCC v8 | Stage IV Retroperitoneal Sarcoma AJCC v8United States
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Massachusetts General HospitalTesaro, Inc.CompletedPancreatic Cancer | Metastatic Pancreatic CancerUnited States
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zr Pharma & GmbHCompletedNeoplasmsUnited Kingdom, Poland, Slovakia
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Zai Lab (Shanghai) Co., Ltd.Completed
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AbbVieCompletedAdvanced Solid TumorsJapan
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University Health Network, TorontoActive, not recruitingOvarian Cancer | Fallopian Tube Cancer | Neoadjuvant Treatment | Debulking Surgical ProceduresCanada, United Kingdom, Spain, New Zealand
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Sichuan UniversityRecruitingLung Cancer | Extensive-stage Small-cell Lung CancerChina
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Haider MahdiGlaxoSmithKline; Zenith EpigeneticsRecruitingOvarian Cancer | Recurrent Solid TumorsUnited States
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Jin LiNot yet recruitingRelapsed Ovarian Cancer
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Xiaoxiang ChenRecruitingNeoplasms | Neoplasms by Histologic Type | Urogenital Neoplasms | Neoplasms by Site | Carcinoma | Neoplasms, Glandular and Epithelial | Genital Neoplasms, Female | Ovarian Diseases | Adnexal Diseases | Carcinoma, Ovarian Epithelial | Ovarian Cancer | Angiogenesis | Genital Diseases, Female | Antineoplastic Agents | BRCA1... and other conditionsChina
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University of PennsylvaniaAstraZeneca; Myriad Genetics, Inc.RecruitingHigh Grade Serous CarcinomaUnited States
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University College, LondonGlaxoSmithKlineWithdrawnRecurrent Glioblastoma
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Sidney Kimmel Comprehensive Cancer Center at Johns...Clovis Oncology, Inc.Active, not recruitingProstate Cancer MetastaticUnited States
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Tesaro, Inc.European Network of Gynaecological Oncological Trial Groups (ENGOT); US Oncology... and other collaboratorsCompletedA Maintenance Study With Niraparib Versus Placebo in Patients With Platinum Sensitive Ovarian CancerOvarian Neoplasms | Platinum Sensitive Ovarian CancerUnited States, Belgium, Sweden, Germany, Israel, Austria, Canada, Denmark, Spain, Italy, United Kingdom, Poland, France, Hungary, Norway
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Melinda TelliPfizer; BioMarin PharmaceuticalCompletedAdvanced Breast Cancer | HER2/Neu Negative | Triple-Negative Breast CancerUnited States
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Zai Lab (Shanghai) Co., Ltd.TerminatedGastric Cancer | Triple Negative Breast Cancer | Endometrial Carcinoma | Biliary Tract CarcinomaChina
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University Health Network, TorontoAstraZenecaCompleted
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AstraZenecaCompletedHead and Neck Squamous Cell CarcinomaTaiwan, United States, France
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Tesaro, Inc.CompletedNeoplasms | Ovarian Neoplasms | Solid Tumor | Hepatic ImpairmentUnited States
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Lisette NixonAstraZenecaUnknownNon-small Cell Lung CancerUnited Kingdom
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Poveda, Andrés, M.D.AstraZeneca; PharmaMarUnknownBreast Cancer | Ovarian Cancer | Endometrial Cancer | Advanced CancerSpain
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National Institutes of Health Clinical Center (CC)National Cancer Institute (NCI)CompletedLymphoma | Leukemia | Unspecified Adult Solid Tumor, Protocol SpecificUnited States
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Shandong UniversitySun Yat-sen University; Zai Lab (Shanghai) Co., Ltd.; Tongji Hospital; Women's...RecruitingEndometrial Carcinoma | Serous CarcinomaChina
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University of Kansas Medical CenterTesaro, Inc.Active, not recruitingPancreatic CancerUnited States
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Assistance Publique - Hôpitaux de ParisCompletedPregnant Women Undergoing TOP | TOP - Failed Attempted Termination of PregnancyFrance
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AstraZenecaActive, not recruitingRelapsed Ovarian Cancer | Following Complete or Partial Response to Platinum Based Chemotherapy | Platinum SensitiveChina, Malaysia
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Tufts Medical CenterMerck Sharp & Dohme LLCActive, not recruitingNeutropenia | Cytomegalovirus Infections | Cytomegalovirus Disease | Heart Transplant Infection | Antiviral ToxicityUnited States
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Tufts Medical CenterRecruitingNeutropenia | Cytomegalovirus Infections | Infection in Solid Organ Transplant Recipients | Antiviral ToxicityUnited States
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Tesaro, Inc.Gynecologic Oncology Group; European Network of Gynaecological Oncological... and other collaboratorsActive, not recruitingOvarian NeoplasmsUnited States, Spain, Finland, Czechia, Italy, Denmark, Germany, Belgium, Israel, Canada, Russian Federation, Sweden, United Kingdom, Poland, Ireland, Ukraine, France, Norway, Switzerland, Hungary
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Spanish Oncology Genito-Urinary GroupAstraZeneca; Apices Soluciones S.L.; Sistemas GenómicosCompleted
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SanofiCompletedAdvanced Solid TumorsUnited States
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University of Michigan Rogel Cancer CenterAstraZeneca; Janssen Scientific Affairs, LLCActive, not recruitingSarcoma | Sarcoma MetastaticUnited States
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EMD Serono Research & Development Institute, Inc.Merck KGaA, Darmstadt, GermanyWithdrawnBreast Cancer | Advanced Solid Tumor
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Institut du Cancer de Montpellier - Val d'AurelleTerminated
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)CompletedInvasive Breast Carcinoma | HER2/Neu Negative | Breast Adenocarcinoma | Deleterious BRCA1 Gene Mutation | Deleterious BRCA2 Gene MutationUnited States